Name and surname:
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prof. Mgr. Radovan Šebesta, DrSc.
|
Document type:
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Research/art/teacher profile of a person
|
The name of the university:
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Comenius University Bratislava
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The seat of the university:
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Šafárikovo námestie 6, 818 06 Bratislava
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III.a - Occupation-position | III.b - Institution | III.c - Duration |
---|---|---|
Postdoc | ETH Zurich, Švajčiarsko | 2003-2004 |
Postdoc | Univerzita v Groningene, Holandsko | 2004-2005 |
Assistant Professor | Comenius University in Bratislava, Faculty of Natural Sciences | 2005-2008 |
Associate Professor | Comeniucs University in Bratislava, Faculty of Natural Sciences | 2008-2015 |
Professor | Comeniucs University in Bratislava, Faculty of Natural Sciences | 2015-present |
V.1.a - Name of the profile course | V.1.b - Study programme | V.1.c - Degree | V.1.d - Field of study |
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Mechanisms of organic reactions | Organic and bioorganic chemistry | II. | Chemistry |
Chemistry of organometallic compounds | Organic and bioorganic chemistry | II. | Chemistry |
Determining the structure of organic compounds | Organic and bioorganic chemistry | II. | Chemistry |
Organic Chemistry | Biological chemistry | I. | Chemistry |
Organic chemistry for advanced students | Organic chemistry | III. | Chemistry |
V.2.a - Name of the study programme | V.2.b - Degree | V.2.c - Field of study |
---|---|---|
Organic and bioorganic chemistry | II. | chemistry |
Organic Chemistry | III. | chemistry |
Biological chemistry | I. | chemistry |
V.3.a - Name of the field of habilitation procedure and inaugural procedure | V.3.b - Study field to which it is assigned |
---|---|
Organic chemistry | chemistry |
V.5.a - Name of the course | V.5.b - Study programme | V.5.c - Degree | V.5.d - Field of study |
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Molecular spectroscopy | chemistry | I. | chemistry |
Bachelor thesis in organic and bioorganic chemistry | chemistry | I. | chemistry |
Asymmetric catalysis | Organic and bioorganic chemistry | II. | chemistry |
Mechanochemical Pd-Catalyzed Amino- and Oxycarbonylations using FeBr2(CO)4 as a CO Source. T. Čarný, P. Kisszékelyi, M. Markovič, T. Gracza, P. Koóš, R. Šebesta, Org. Lett. 2023, 25, 8617–8621. (https://doi.org/10.1021/acs.orglett.3c03440)
Mechanochemically Activated Asymmetric Organocatalytic Domino Mannich Reaction-Fluorination. D. Krištofíková, M. Mečiarová, E. Rakovský, R. Šebesta, ACS Sust. Chem. Eng. 2020, 8, 14417–14424. (https://pubs.acs.org/doi/full/10.1021/acssuschemeng.0c04260)
Trapping of chiral enolates generated by Lewis acid promoted conjugate addition of Grignard reagents to unreactive Michael acceptors by various electrophiles. D. Vargová, J. M. Perez, S. R. Harutyunyan, R. Šebesta, Chem. Commun. 2019, 55, 11766-11769. (https://doi.org/10.1039/C9CC05041H)
Asymmetric one-pot conjugate addition of Grignard reagents to α,β-unsaturated compounds followed by reaction with carbenium ions. M. Drusan, E. Rakovský, J. Marek, R. Šebesta, Adv. Synth. Catal. 2015, 357, 1493-1498. ( https://doi.org/10.1002/adsc.201500074)
Catalysts with ionic tags and their use in ionic liquids. Šebesta, R.; Kmentová, I.; Toma, Š. Green Chem. 2008, 10, 484-496. (https://doi.org/10.1039/B801456F)
Mechanochemical Pd-Catalyzed Amino- and Oxycarbonylations using FeBr2(CO)4 as a CO Source. T. Čarný, P. Kisszékelyi, M. Markovič, T. Gracza, P. Koóš, R. Šebesta, Org. Lett. 2023, 25, 8617–8621. (https://doi.org/10.1021/acs.orglett.3c03440)
Organocatalytic Diastereodivergent Enantioselective Formal oxa-Diels-Alder Reaction of Unsaturated Ketones with Enoates Under Liquid-Assisted Grinding Conditions. T. Peňaška, V. Modrocká, K. Stankovianska, M. Mečiarová, E. Rakovský, R. Šebesta, ChemSusChem 2022, e202200028. (https://doi.org/10.1002/cssc.202200028)
Hybrid Peptide–Thiourea Catalyst for Asymmetric Michael Additions of Aldehydes to Heterocyclic Nitroalkenes, P. Čmelová, D. Vargová, R. Šebesta, J. Org. Chem. 2021, 86, 581-592. (https://doi.org/10.1021/acs.joc.0c02251)
Mechanochemically Activated Asymmetric Organocatalytic Domino Mannich Reaction-Fluorination. D. Krištofíková, M. Mečiarová, E. Rakovský, R. Šebesta, ACS Sust. Chem. Eng. 2020, 8, 14417–14424. (https://doi.org/10.1002/cssc.202000137)
Trapping of chiral enolates generated by Lewis acid promoted conjugate addition of Grignard reagents to unreactive Michael acceptors by various electrophiles. D. Vargová, J. M. Perez, S. R. Harutyunyan, R. Šebesta, Chem. Commun. 2019, 55, 11766-11769. (https://doi.org/10.1039/C9CC05041H)
Org. Lett. 2023, 25, 8617: Xiang, K., Shou, H., Hu, C., Su, W., Yu, J.; Mechanochemical aerobic oxidative Heck coupling by polymer-assisted grinding: cyclodextrin additive facilitating regioselectivity control. Green Chem., 2024, 26, 5890-5899.
ACS Sust. Chem. Eng. 2020, 8, 14417: Williams, M.T.J., Morrill, L.C., Browne, D.L. Mechanochemical Organocatalysis: Do High Enantioselectivities Contradict What We Might Expect? ChemSusChem, 2022, 15, e202102157.
Chem. Commun. 2019, 55, 11766: Feng, S., Dong, Y., Buchwald, S.L.; Enantioselective Hydrocarbamoylation of Alkenes. Angew. Chem. Int. Ed., 2022, 61, e202206692.
Adv. Synth. Catal. 2015, 357, 1493: Wang, J.Y.J., Palacin, T., Fletcher, S.P.; β-Chloroaldehydes from Trapping Zirconium Enolates Produced in Asymmetric 1,4-Additions (2019) Organic Letters, 21 (2), pp. 378-381.
Green Chem. 2008, 10, 484: Limberger, J., Leal, B.C., Monteiro, A.L., Dupont, J. Charge-tagged ligands: Useful tools for immobilising complexes and detecting reaction species during catalysis. Chem. Sci. 2015, 6 , 77-94.
Fine organometallic compounds for green synthesis and catalysis; 2023-2027; APVV-22-0167
Preparation of new drugs and their intermediates based on chiral pyrrolidines; 2016-2019; APVV-15-0039
Assisted mechanical milling for catalytic synthesis; 2024-2027; VEGA 1/0445/24
Asymmetric multicatalysis for efficient synthesis of chiral carbocyclic and heterocyclic compounds; 2019-2023; APVV-18-0242
New antiviral drugs: Design, synthesis and activity testing of novel specific inhibitors of SARS-CoV-2 viral coronavirus proteases; 2020-2021; APVV-PP-COVID-20-0010
VII.a - Activity, position | VII.b - Name of the institution, board | VII.c - Duration |
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Member of the Scientific Council of PriF UK | Comenius University in Bratislava, Faculty of Natural Sciences | 2020-present |
Member of the Scientific Council of the PF UPJŠ | Pavel Jozef Šafárik University in Košice, Faculty of Science | 2019-present |
Member of the Scientific Council, Institute of Polymers of the Slovak Academy of Sciences | Institute of Polymers of the Slovak Academy of Sciences | 2018-2022 |
Editor and member of the editorial board of Chemical Papers | Chemical Papers (Springer) | 2016-present |
VIII.a - Name of the institution | VIII.b - Address of the institution | VIII.c - Duration (indicate the duration of stay) | VIII.d - Mobility scheme, employment contract, other (describe) |
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ETH Zurich (research group of Prof. Dieter Seebach) | Zurich, Switzerland | 2003-2004 (19 months) | Postdoc (work contract) |
University of Groningen (Prof. Ben Feringa's research group) | Groningen, Netherlands | 2004-2005 (12 months) | Postdoc (work contract) |
1. Chairman of the Expert Group for Organic Chemistry in the Slovak Chemical Society.
2. Guest editor of two thematic issues of the Beilstein Journal of Organic Chemistry devoted to asymmetric organocatalysis (2022, 2024).