Rumanova VS, Okuliarova M, Zeman M: Differential effects of constant light and dim light at night on the circadian control of metabolism and behavior. International Journal of Molecular Sciences, 21: 5478, 2020.

Okuliarova M, Molcan L, Zeman M: Decreased emotional reactivity of rats exposed to repeated phase shifts of light–dark cycle. Physiology & Behavior, 156: 16-23, 2016.

Okuliarova M, Groothuis TGG, Skrobanek P, Zeman M: Experimental evidence for genetic heritability of maternal hormone transfer to offspring. American Naturalist, 177 (6): 824-834, 2011.

Okuliarova M, Sarnikova B, Rettenbacher S, Skrobanek P, Zeman M: Yolk testosterone and corticosterone in hierarchical follicles and laid eggs of Japanese quail exposed to long-term restraint stress. General and Comparative Endocrinology, 165 (1): 91-96, 2010.

Okuliarova M, Skrobanek P, Zeman M: Effect of increasing yolk testosterone levels on early behaviour in Japanese quail hatchlings. Acta Veterinaria Brno, 76 (3): 325-331, 2007.

Okuliarova M, Mazgutova N, Majzunova M, Rumanova VS, Zeman M: Dim light at night impairs daily variation of circulating immune cells and renal immune homeostasis. Frontiers in Immunology, 11: 614960, 2021.

Okuliarova M, Dzirbikova Z, Rumanova VS, Foppen E, Kalsbeek A, Zeman M: Disrupted circadian control of hormonal rhythms and anticipatory thirst by dim light at night. Neuroendocrinology, 112: 1116–1128, 2022.

Jerigova V, Zeman M, Okuliarova M: Circadian disruption and consequences on innate immunity and inflammatory response. International Journal of Molecular Sciences, 23: 13722, 2022.

Jerigova V, Zeman M, Okuliarova M: Chronodisruption of the acute inflammatory response by night lighting in rats. Scientific Reports, 13: 14109, 2023.

Okuliarova M, Rumanova VS, Stebelova K, Zeman M: Dim light at night disturbs molecular pathways of lipid metabolism. International Journal of Molecular Sciences, 21: 6919, 2020.

Jerigova V, Zeman M, Okuliarova M: Circadian disruption and consequences on innate immunity and inflammatory response. International Journal of Molecular Sciences, 23: 13722, 2022. Cited in: 1.Zielinska-Dabkowska KM, Schernhammer ES, Hanifin JP, Brainard GC: Reducing nighttime light exposure in the urban environment to benefit human health and society. Science, 380: 1130-1135, 2023.

Okuliarova M, Rumanova VS, Stebelova K, Zeman M: Dim light at night disturbs molecular pathways of lipid metabolism. International Journal of Molecular Sciences, 21: 6919, 2020. Cited in: 1.Guan Q, Wang Z, Cao J, Dong Y, Tang S, Chen Y: Melatonin restores hepatic lipid metabolic homeostasis disrupted by blue light at night in high-fat diet-fed mice. Journal of Pineal Research, 76: 2024.

Okuliarova M, Mazgutova N, Majzunova M, Rumanova VS, Zeman M: Dim light at night impairs daily variation of circulating immune cells and renal immune homeostasis. Frontiers in Immunology, 11: 614960, 2021. Cited in: 1.de Toledo LHS, Moraes MN, Poletini MDO, Neto JC, Baron J, Mota T: Modeling the influence of nighttime light on melatonin suppression in humans: Milestones and perspectives. Journal of Photochemistry and Photobiology, 16: 2023.

Okuliarova M, Groothuis TGG, Skrobanek P, Zeman M: Experimental evidence for genetic heritability of maternal hormone transfer to offspring. American Naturalist, 177 (6): 824-834, 2011. Cited in: Pick JL, Ebneter C, Hutter P, Tschirren B: Disentangling genetic and prenatal maternal effects on offspring size and survival. American Naturalist, 188: 628-639, 2016.

Okuliarova M, Sarnikova B, Rettenbacher S, Skrobanek P, Zeman M: Yolk testosterone and corticosterone in hierarchical follicles and laid eggs of Japanese quail exposed to long-term restraint stress. General and Comparative Endocrinology, 165 (1): 91-96, 2010. Cited in: Carsia RV: Chapter 26 - Adrenals. In: Scanes CG (Ed.) Sturkie's avian physiology, sixth edition. San Diego, USA: Elsevier Inc., s. 577-611, 2015.

VEGA 1/0565/22 (2022 - 2025) Consequences of circadian disruption on metabolic reprogramming during inflammation (Principal investigator), Annotation: Metabolic pathways are important in the control of the immune system, and both metabolism and immunity are regulated by the circadian clock. Mutual crosstalk between these three systems may therefore be important for understanding the causal mechanisms leading from circadian disruption to chronic inflammatory diseases. In this project, we will analyse the metabolic response following immune stimulation as a function of time of day, both at the systemic and cellular level in a Wistar rat model. We focus one metabolic reprogramming in inflammatory macrophages to investigate the extent to which the adaptation of metabolic demands in the inflammatory response is impaired by circadian disruption induced by dim light at night.

VEGA 1/0501/19 (2019 - 2021) The role of prenatal environment in the modulation of physiological and behavioural phenotype in poultry (Principal investigator), Annotation: The project aimed to study maternal (maternal androgens, nutritional factors and immune substances deposited in eggs) and exogenous factors (lighting regime during the egg incubation) that form the embryonic environment in the egg and have a high potential to influence the developmental program of an individual. This can lead to significant long-term consequences that we addressed in the terms of postnatal performance, health and welfare as the dominant determinants of poultry productivity.

APVV-21-0164 (2022 - 2026) Healthy aging: effects of lifelong and time-specific exercise on functional, structural, metabolic and immune parameters in circadian context (Principal investigator for the faculty), Annotation: The aim of the project is to investigate the effect of lifelong endurance training on the stability of the circadian system in ageing and to assess the benefits of regular physical activity in improving the circadian regulation of physiological processes. We will focus on sleep/wake rhythms, sleep quality, melatonin production, immune and hormonal parameters, as well as cardiorespiratory function, body composition and skeletal muscle quality. Another aim is to experimentally verify the effect of combined strength and endurance training on the above parameters in a group of physically inactive older adults and to demonstrate the importance of a time-of-day specific exercise intervention on parameters of circadian regulation, immune function, fitness, body composition and metabolic health in a healthy elderly population.

APVV-21-0223 (2022 - 2026) Reinforcement of attenuated circadian control of vital functions as a prevention of civilization diseases (Member of research team), Annotation: Artificial light at night (ALAN) is detrimental to biodiversity and very likely to human well-being and health. However, the underlying physiological mechanisms have not been studied in detail and therefore light pollution control measures are still inadequate. The aim of this project is to investigate the functional consequences of ALAN-induced disrupted daily rhythms in metabolic, cardiovascular, immune and behavioural parameters using a complex methodological approach from the molecular, cellular to the systemic level. In parallel, we will investigate the possibility of reinforcing the impaired circadian organisation by non-pharmacological (time-restricted feeding and regular physical activity) and pharmacological interventions.

APVV-17-0178 (2018 - 2022) Impact of circadian disruption induced by artificial light at night on physiological and behavioural processes (Member of research team), Annotation: Artificial light at night is probably the most visible human intervention to the external environment and its impact on ecology and human health is not clear. Disruption of a natural light-dark cycle can negatively affect entrainment of circadian rhythms with periodic changes in outside world. Mechanisms how disturbed circadian rhythms may lead to the development of chronic diseases are poorly understood. In our project, we explore the impact of artificial light at night on circadian rhythms in the cardiovascular system, an activity of the immune system, metabolism and behaviour.