Research/art/teacher profile of a person
Name and surname:
Ing. Martina Neboháčová, PhD.
Document type:
Research/art/teacher profile of a person
The name of the university:
Comenius University Bratislava
The seat of the university:
Šafárikovo námestie 6, 818 06 Bratislava

I. - Basic information

I.1 - Surname
Neboháčová
I.2 - Name
Martina
I.3 - Degrees
Ing., PhD.
I.4 - Year of birth
1968
I.5 - Name of the workplace
Department of Biochemistry, Faculty of Natural Sciences Comenius university in Bratislava
I.6 - Address of the workplace
Mlynská dolina, Ilkovičova 6, 842 15 Bratislava 4
I.7 - Position
assistant professor
I.8 - E-mail address
martina.nebohacova@uniba.sk
I.9 - Hyperlink to the entry of a person in the Register of university staff
https://www.portalvs.sk/regzam/detail/5234
I.10 - Name of the study field in which a person works at the university
Chemistry
I.11 - ORCID iD
0000-0003-4486-2713

II. - Higher education and further qualification growth

II.1 - First degree of higher education
II.2 - Second degree of higher education
II.a - Name of the university or institution
Faculty of Chemical Technologies, Slovak Technical University in Bratislava
II.b - Year
1992
II.c - Study field and programme
Yeast Technologies and Bioengineering
II.3 - Third degree of higher education
II.a - Name of the university or institution
Faculty of Natural Sciences, Comenius University in Bratislava
II.b - Year
2000
II.c - Study field and programme
Biochemistry
II.4 - Associate professor
II.5 - Professor
II.6 - Doctor of Science (DrSc.)

III. - Current and previous employment

III.a - Occupation-position III.b - Institution III.c - Duration
assistant professor Faculty of Natural Sciences, Comenius University in Bratislava 2007-today
visiting assistant researcher University of California Los Angeles, USA 2005-2007
research associate Howard Hughes Research Institute at University of California Los Angeles, USA 2002-2005
postdoctoral fellow University of California Los Angeles, USA 2001-2002
postdoctoral fellow University of California Riverside, USA 2000-2001

IV. - Development of pedagogical, professional, language, digital and other skills

IV.a - Activity description, course name, other IV.b - Name of the institution IV.c - Year
Scientific qualification level IIa Slovak Academy of Sciences, SAS Commission for Assessment of Scientific Qualification of Employees 2016
Certificate of completion of an accredited training program on professional competence to work with very toxic substances and mixtures and with toxic substances and mixtures, certificate registration number: 3706/2021/11/3 Axelum, s.r.o., Rovniankova 15, 85102 Bratislava 2022
Certificate of professional competence to work with toxic substances and mixtures and very toxic substances and mixtures, certificate registration number: OOD/14180/2012 Regional Public Health Office, Bratislava 2012

V. - Overview of activities within the teaching career at the university

V.1 - Overview of the profile courses taught in the current academic year according to study programmes
V.1.a - Name of the profile course V.1.b - Study programme V.1.c - Degree V.1.d - Field of study
Methods in Molecular and Cellular Biology Biochemistry I. Chemistry
Bachelor Thesis in Biochemistry (2) Biochemistry I. Chemistry
Advanced Practical in Biochemistry and Cell Biology Biochemistry II. Chemistry
Molecular biology of the cell (1) Biochemistry II. Chemistry
Genomics Biochemistry II. Chemistry
Biochemistry (2) Biochemistry I. Chemistry
V.2 - Overview of the responsibility for the delivery, development and quality assurance of the study programme or its part at the university in the current academic year
V.3 - Overview of the responsibility for the development and quality of the field of habilitation procedure and inaugural procedure in the current academic year
V.4 - Overview of supervised final theses
V.4.1 - Number of currently supervised theses
V.4.a - Bachelor's (first degree)
3
V.4.b - Diploma (second degree)
2
V.4.c - Dissertation (third degree)
0
V.4.2 - Number of defended theses
V.4.a - Bachelor's (first degree)
21
V.4.b - Diploma (second degree)
14
V.4.c - Dissertation (third degree)
1
V.5 - Overview of other courses taught in the current academic year according to study programmes
V.5.a - Name of the course V.5.b - Study programme V.5.c - Degree V.5.d - Field of study
Practical in Biochemistry and Cell Biology Biochemistry I. Chemistry
Advanced Practical in Biochemistry Biological Chemistry I. Biology
Structure and Function of Biomolecules Biological Chemistry I. Biology
Perspectives of Biochemistry Biochemistry I. Chemistry
Seminar from molecular biology of the cell (1) Biochemistry II. Chemistry
Advanced genetics (2) - Mutagenesis and genotoxicology Genetics II. Biology

VI. - Overview of the research/artistic/other outputs

VI.1 - Overview of the research/artistic/other outputs and the corresponding citations
VI.1.1 - Number of the research/artistic/other outputs
VI.1.a - Overall
24
VI.1.b - Over the last six years
6
VI.1.2 - Number of the research/artistic/other outputs registered in the Web of Science or Scopus databases
VI.1.a - Overall
24
VI.1.b - Over the last six years
6
VI.1.3 - Number of citations corresponding to the research/artistic/other outputs
VI.1.a - Overall
284
VI.1.b - Over the last six years
114
VI.1.4 - Number of citations registered in the Web of Science or Scopus databases
VI.1.a - Overall
284
VI.1.b - Over the last six years
114
VI.1.5 - Number of invited lectures at the international, national level
VI.1.a - Overall
1
VI.1.b - Over the last six years
0
VI.2 - The most significant research/artistic/other outputs
1

Vrzoňová R, Tóth R, Siváková B, Moťovská A, Gaplovská-Kyselá K, Baráth P, Tomáška Ľ, Gácser A, Gabaldón T, Nosek J, Neboháčová M.: OCT1-a yeast mitochondrial thiolase involved in the 3-oxoadipate pathway. FEMS Yeast Research [elektronický dokument]. - Roč. 21, č. 5 (2021), s. [1-12], art. no. foab034 [print]. ISSN 1567-1356

2

Lang BF, Jakubkova M, Hegedusova E, Daoud R, Forget L, Brejova B, Vinar T, Kosa P, Fricova D, Nebohacova M, Griac P, Tomaska L, Burger G, Nosek J.: Massive programmed translational jumping in mitochondria, In: Proceedings of the National Academy of Sciences of the United States of America. - Vol. 111, No. 16 (2014), s. 5926-5931.

3

Neboháčová, Martina [UKOPRCBI] (40%) - Kim, Christine E. (10%) - Simpson, Larry (10%) - Maslov, Dmitri A. (40%): RNA editing and mitochondrial activity in promastigotes and amastigotes of Leishmania donovani. In: International Journal for Parasitology. - Vol. 39, No. 6 (2009), s. 635-644. - ISSN 0020-7519

4

Mehrabian, M. (15%) - Schulthess, F. T. (15%) - Neboháčová, Martina [UKOPRCBI] (15%) - Castellani, L. W. (2,5%) - Zhou, Z. (2,5%) - Hartiala, J. (2,5%) - Oberholzer, J. (2,5%) - Lusis, A. J. (15%) - Maedler, K. (15%) - Allayee, H. (15%):Identification of ALOX5 as a gene regulating adiposity and pancreatic function, In: Diabetologia. - Vol. 51, No. 6 (2008), s. 978-988. - ISSN 0012-186X

5

Neboháčová, Martina [UKOPRCBI] - Maslov, Dmitri A. - Falick, Arnold M. - Simpson, Larry: The effect of RNA interference down-regulation of RNA editing 3 '-terminal uridylyl transferase (TUTase) 1 on mitochondrial de novo protein synthesis andstability of respiratory complexes in Trypanosoma brucei. In: Journal of Biological Chemistry. - Vol. 279, No. 9 (2004), s. 7819-7825. - ISSN 0021-9258

VI.3 - The most significant research/artistic/other outputs over the last six years
1

Vrzoňová R, Tóth R, Siváková B, Moťovská A, Gaplovská-Kyselá K, Baráth P, Tomáška Ľ, Gácser A, Gabaldón T, Nosek J, Neboháčová M.: OCT1-a yeast mitochondrial thiolase involved in the 3-oxoadipate pathway. FEMS Yeast Research [elektronický dokument]. - Roč. 21, č. 5 (2021), s. [1-12], art. no. foab034 [print]. ISSN 1567-1356

2

Cillingová A, Tóth R, Mojáková A, Zeman I, Vrzoňová R, Siváková B, Baráth P, Neboháčová M, Klepcová Z, Brázdovič F, Lichancová H, Hodorová V, Brejová B, Vinař T, Mutalová S, Vozáriková V, Mutti G, Tomáška Ľ, Gácser A, Gabaldón T, Nosek J.: Transcriptome and proteome profiling reveals complex adaptations of Candida parapsilosis cells assimilating hydroxyaromatic carbon sources. PLoS Genetics 2022 Mar 7;18(3):e1009815. doi: 10.1371/journal.pgen.1009815

3

Broňa Brejová, Kristína Boršová, Viktória Hodorová, Viktória Čabanová, Askar Gafurov, Dominika Fričová, Martina Neboháčová, Tomáš Vinař, Boris Klempa, Jozef Nosek: Nanopore sequencing of SARS-CoV-2: Comparison of short and long PCR-tiling amplicon protocols. PLoS One [elektronický dokument]. - Roč. 16, č. 10 (2021), s. [1-17], art. no. e0259277 [online], ISSN 1932-6203

4

Brejová B, Lichancová H, Brázdovič F, Hegedűsová E, Forgáčová Jakúbková M, Hodorová V, Džugasová V, Baláž A, Zeiselová L, Cillingová A, Neboháčová M, Raclavský V, Tomáška Ľ, Lang BF, Vinař T, Nosek J.: Genome sequence of the opportunistic human pathogen, Magnusiomyces capitatus. In: Current Genetics. - Roč. 65, č. 2 (2019), s. 539-560. - ISSN (print) 0172-8083

5

Brejová B, Lichancová H, Hodorová V, Neboháčová M, Tomáška Ľ, Vinař T, Nosek J.: Genome Sequence of an Arthroconidial Yeast, Saprochaete fungicola CBS 625.85. Microbiology Resource Announcements 2019 Apr 11;8(15):e00092-19. doi: 10.1128/MRA.00092-19

VI.4 - The most significant citations corresponding to the research/artistic/other outputs
1

Lang BF, Jakubkova M, Hegedusova E, Daoud R, Forget L, Brejova B, Vinar T, Kosa P, Fricova D, Nebohacova M, Griac P, Tomaska L, Burger G, Nosek J.: Massive programmed translational jumping in mitochondria, In: Proceedings of the National Academy of Sciences of the United States of America. - Vol. 111, No. 16 (2014), s. 5926-5931.

Citation [n1] 2022 Hao, W.: From Genome Variation to Molecular Mechanisms: What we Have Learned From Yeast Mitochondrial Genomes?. In: Frontiers in Microbiology, Vol. 13, January, 2022, Art. No. 806575 -- SCOPUS ; SCI


2

Neboháčová, Martina [UKOPRCBI] (40%) - Kim, Christine E. (10%) - Simpson, Larry (10%) - Maslov, Dmitri A. (40%): RNA editing and mitochondrial activity in promastigotes and amastigotes of Leishmania donovani. In: International Journal for Parasitology. - Vol. 39, No. 6 (2009), s. 635-644. - ISSN 0020-7519

Citation [o1] 2011 Lukes, J. - Hashimi, H. - Verner, Z. - Cicova, Z.: The Remarkable Mitochondrion of Trypanosomes and Related Flagellates. In: Structures and Organelles in Pathogenic Protists. Book Series: Microbiology Monographs, Vol. 17. New York :Springer, 2011, S. 227-252 - BKCI-S

3

Gérecová G, Neboháčová M, Zeman I, Pryszcz LP, Tomáška Ľ, Gabaldón T, Nosek J.: Metabolic gene clusters encoding the enzymes of two branches of the 3-oxoadipate pathway in the pathogenic yeast Candida albicans. FEMS Yeast Res. 2015 May;15(3):fov006. doi: 10.1093/femsyr/fov006

Citation [n1] 2021 Lubbers, R.J.M. - de, Vries R.P.: Degradation of homocyclic aromatic compounds by Fungi. In: Encyclopedia of Mycology. Amsterdam : Elsevier, 2021, S. 477-488 -- SCOPUS

4

Mehrabian, M. (15%) - Schulthess, F. T. (15%) - Neboháčová, Martina [UKOPRCBI] (15%) - Castellani, L. W. (2,5%) - Zhou, Z. (2,5%) - Hartiala, J. (2,5%) - Oberholzer, J. (2,5%) - Lusis, A. J. (15%) - Maedler, K. (15%) - Allayee, H. (15%):Identification of ALOX5 as a gene regulating adiposity and pancreatic function, In: Diabetologia. - Vol. 51, No. 6 (2008), s. 978-988. - ISSN 0012-186X.

Citation [n1] 2021 Ganteil, A. - Rodriguez-Ramilo, S.T. - Ligonesche, B. - Larzul, C.: Characterization of Autozygosity in Pigs in Three-Way Crossbreeding. In: Frontiers in Genetics, Vol. 11, January, 2021, Art. No. 584556 -- SCOPUS ; SCI


5

Neboháčová, Martina [UKOPRCBI] - Maslov, Dmitri A. - Falick, Arnold M. - Simpson, Larry: The effect of RNA interference down-regulation of RNA editing 3 '-terminal uridylyl transferase (TUTase) 1 on mitochondrial de novo protein synthesis andstability of respiratory complexes in Trypanosoma brucei. In: Journal of Biological Chemistry. - Vol. 279, No. 9 (2004), s. 7819-7825. - ISSN 0021-9258:

Citation [n1] 2021 Duarte, M. - Ferreira, C. - Khandpur, G.K. - Flohr, T. - Zimmermann, J. - Castro, H. - Herrmann, J. M. - Morgan, B. - Tomás, A.M.: Leishmania type II dehydrogenase is essential for parasite viability irrespective of thepresence of an active complex I. In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, No. 42, 2021, Art. No. e2103803118 -- SCOPUS ; SCIC

VI.5 - Participation in conducting (leading) the most important research projects or art projects over the last six years
1

Principal investigator

Peroxisomal biogenesis and metabolism in pathogenic yeasts. The project is focused on comparative and functional analysis of biogenesis and metabolism of peroxisomes in order to elucidate the role of these organelles in the physiology of pathogenic yeasts.

VEGA 1/0136/20 (2020-2023)

2

Team member 

Comparative transcriptomics as a window into the world of fundamental biological processes. The project is focused on the comparative analysis of transcriptomes of unconventional yeast species.

APVV 22-0144 (2023-2027)

3

Team member

Exploring yeast biodiversity for uncovering novel mechanisms of telomere maintenance of eukaryotic chromosomes. The project is aimed at finding new ways of maintaining chromosome ends.

APVV 19-0068  (2020-2024)

4

Team member

Non-conventional applications of emerging sequencing technologies in comparative and functional genomics. The project is focused on new experimental and bioinformatics methods that in combination with the third-generation sequencing technologies allow determination of highly-contiguous sequences of non-conventional yeast species. 

APVV-18-0239 (2019-2023)

5

Team member

Functional analysis of metabolic gene clusters coding for the enzymes of catabolic degradation of hydroxyaromatic

compounds. The project is focused on the analysis of biochemical pathways involved in the degradation of hydroxyaromatic compounds and their integration with the central metabolism of eukaryotic cells.

VEGA 1/0027/19 (2019-2022)

VII. - Overview of organizational experience related to higher education and research/artistic/other activities

VII.a - Activity, position VII.b - Name of the institution, board VII.c - Duration
Member of the examination commission for state bachelor's degree exams Faculty of Natural Sciences, Comenius University in Bratislava, Department of Biochemistry 2011-today
Member of the examination commission for state master's degree exams Faculty of Natural Sciences, Comenius University in Bratislava, Department of Biochemistry 2015-today
member of Academic senate of Faculty of Natural Sciences, Comenius University Faculty of Natural Sciences, Comenius University in Bratislava 2010-2011

VIII. - Overview of international mobilities and visits oriented on education and research/artistic/other activities in the given field of study

VIII.a - Name of the institution VIII.b - Address of the institution VIII.c - Duration (indicate the duration of stay) VIII.d - Mobility scheme, employment contract, other (describe)
Institute of Physiology Czech Academy of Sciences Vídeňská 1083, 142 00 Praha 4, Czech Republic 09/2007, 04/06/11/2009, 07/11/2010 business travel
University of South Bohemia in České Budějovice Branišovská 31, České Budějovice, Czech Republic 09/2007 business travel/invited speaker
University of California, Los Angeles Division of Cardiology, Geffen School of Medicine, UCLA, Los Angeles, USA 2005-2007 employment contract
Howard Hughes Medical Institute, UCLA University of California, Los Angeles, USA 2002-2005 employment contract
University of California, Los Angeles Department of Microbiology, Immunology and Molecular Genetics, University of California Los Angeles, USA 2001-2002 employment contract
University of California, Riverside Department of Biology, University of California Riverside, USA 2000-2001 employment contract
Leiden University Laboratory of Yeast Genetics, Institute of Molecular Plant Science, Leiden University, the Netherlands 1994-1995 program TEMPUS (Trans-European Mobility Programme for University Studies)
Queen’s University Belfast Queen’s University, Belfast, Northern Ireland 03-09/1991 programme IAESTE (The International Association for the Exchange of Students for Technical Experience)

IX. - Other relevant facts

IX.a - If relevant, other activities related to higher education or research/artistic/other activities are mentioned

Theoretical and practical preparation of high school students for the International Biology Olympiad, 2012-2023 (https://www.iuventa.sk/sk/Olympiady/olympiady/BiO.alej)

Supervision of the practical project of high school student in the Secondary School Professional Activity (SOČ), 2019-2021

Date of last update
2025-02-17