Name and surname:
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Mgr. Natalia Lucia Miklášová, PhD.
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Document type:
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Research/art/teacher profile of a person
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The name of the university:
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Comenius University Bratislava
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The seat of the university:
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Šafárikovo námestie 6, 818 06 Bratislava
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III.a - Occupation-position | III.b - Institution | III.c - Duration |
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Scientist - reseracher | Faculty of Natural Sciences, Department of Organic Chemistry, UK | 2006-2008 |
Assistant professor | Faculty of Pharmacy, Department of Chemical Theory of Drugs, UK | 2008-present |
IV.a - Activity description, course name, other | IV.b - Name of the institution | IV.c - Year |
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Protection of animals used for scientific or educational purposes | Institute of Postgraduate Education of Veterinary | 2015 |
V.5.a - Name of the course | V.5.b - Study programme | V.5.c - Degree | V.5.d - Field of study |
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Selected topics in organic chemistry | Pharmacy | MSc | Pharmacy |
Organic Chemistry I | Pharmacy | MSc | Pharmacy |
Organic Chemistry II | Pharmacy | MSc | Pharmacy |
The CellScan Technology for In Vitro Studies on Novel Platinum Complexes with Organoarsenic Ligands”, Eva Fischer Fodor, Natalia Moldovan, Piroska Virag, Olga Soritau, Ioana Brie, Peter Lönnecke, Evamarie Hey-Hawkins, Luminita Silaghi-Dumitrescu, Dalton Transactions, 2008, pp. 6393-6400.
Antiproliferative effect of novel platinum(II) and palladium(II) complexes on hepatic tumor stem cells in vitro, Miklášová, N., Fischer-Fodor, E., Lönnecke, P., Tomuleasa, C.I., Virag, P., Perde Schrepler, M., Mikláš, R., Silaghi Dumitrescu, L., Hey-Hawkins, E., European Journal of Medicinal Chemistry 49, 2012, pp. 41-47.
Novel palladium(II) complexes that influence prominin-1/CD133 expression and stem cell factor release in tumor cells, Fischer-Fodor, E., Mikláš R., Rišiaňová L., Cenariu M., Gşrosu I.-G., Virag P., Perde Schrepler M., Tomuleasa C., Berindan-Neagoe I., Devínsky, F., Miklášová, N., Molecules, 22(561), 2017, doi;10.3390/molecules22040561
Synthesis, structural characterization and biological activity of novel Knoevenagel condensates on DLD-1 human colon carcinoma, Rišiaňová L., Fischer-Fodor, E., Valentová J., Tatomir C., Decea N.C., Virag P., Pechová I., Devínsky, F., Miklášová, N., Bioorganic & Medicinal Chemistry Letters, 27, 2017, pp. 2345-2349.
Evaluation of antiproliferative palladium(II) complexes of synthetic bisdemethoxycurcumin towards in vitro cytotoxicity and molecular docking on DNA sequence. Miklášová, Natalia; Herich, Peter; Dávila-Becerril, Juan Carlos; Barroso-Flores, Joaquín; Fischer-Fodor, Eva; Valentová, Jindra; Leskovská, Janka; Kožíšek, Jozef; Takáč, Peter; Mojžiš, Ján. Molecules, Open Access, 26(142) 2021 Article number 4369.
Novel palladium(II) complexes that influence prominin-1/CD133 expression and stem cell factor release in tumor cells, Fischer-Fodor, E., Mikláš, R., Rišiaňová L., Cenariu M., Gşrosu I.-G., Virag P., Perde Schrepler M., Tomuleasa C., Berindan-Neagoe I., Devínsky, F., Miklášová, N., Molecules, 22(561), 2017, doi;10.3390/molecules22040561.
Synthesis, structural characterization and biological activity of novel Knoevenagel condensates on DLD-1 human colon carcinoma, Rišiaňová L., Fischer-Fodor, E., Valentová J., Tatomir C., Decea N.C., Virag P., Pechová I., Devínsky, F., Miklášová, N., Bioorganic & Medicinal Chemistry Letters, 27, 2017, pp. 2345-2349.
Modulatory effect of curcumin analogs on the activation of metalloproteinases in human periodontal stem cells, Boşca A.B., Ilea A., Sorițău O., Tatomir C., Miklášová N., Pȃrvu A. E., Mihu C. M., Melnicovici C.S., Fischer-Fodor E., European Journal of Oral Sciences, 2019, 1-9.
Evaluation of antiproliferative palladium(II) complexes of synthetic bisdemethoxycurcumin towards in vitro cytotoxicity and molecular docking on DNA sequence. Miklášová, Natalia; Herich, Peter; Dávila-Becerril, Juan Carlos; Barroso-Flores, Joaquín; Fischer-Fodor, Eva; Valentová, Jindra; Leskovská, Janka; Kožíšek, Jozef; Takáč, Peter; Mojžiš, Ján. Molecules, Open Access, 26(142) 2021 Article number 4369.
Antiproliferative Ruthenium Complexes Containing Curcuminoid Ligands Tested In Vitro on Human Ovarian Tumor Cell Line A2780, towards Their Capability to Modulate the NF-κBTranscription Factor, FGF-2 Growth Factor, and MMP-9 Pathway. Leskovská, Janka;Miklášová, Natalia; Kubelac, Paul Milan; Achimaş-Cadariu, Patriciu; Valentová, Jindra; Markuliak, Mário;Fischer-Fodor, Eva. Molecules (Basel, Switzerland) Open Access Volume 27, Issue 1418 July 2022
Tuning the coordination properties of phenothiazine by regioselective introduction of diphenylphosphanyl groups, Filip, I.H.,Gál, E., Lupan, I., Perde-Schrepler, M., Lönnecke, P., Surducan, M., Gəinə, L.I., Hey-Hawkins, E., Silaghi-Dumitrescu, L., 2015, Dalton Trans, 44(2), pp. 615-629.
Cyclometalated Palladium(II) N-Heterocyclic Carbene Complexes: Anticancer Agents for Potent In Vitro Cytotoxicity and In Vivo Tumor Growth Suppression, Fong, T.T.-H., Lok, C.-N., Chung, C.Y.-S., Fung, Y.-M.E., Chow, P.-K., Wan, P.-K., Che, C.-M., 2016, Angewandte Chemie - International Edition, 55(39), pp. 11935-11939.
Non-platinum complexes containing releasable biologically active ligands, Štarha, Pavel; Trávníček, Zdeněk, 2019, Coordination Chemistry Reviews, Volume 395, Pp. 130 – 14515
Curcumin analogues and their hybrid molecules as multifunctional drugs (Review), Noureddin, S.A., El-Shishtawy, R.M., Al-Footy, K.O., European Journal of Medicinal Chemistry, 2019, 182, article no. 111631.
New palladium(II) and platinum(II) complexes with an ONS donor azo-thioether pincer ligand: synthesis, characterization, protein binding study and in vitro cytotoxicity, Das, Akash; Saha, Moumita; Mandal, Subrata; Das, Sanjib; Das Saha, Krishna; Mondal, Tapan K, 2023, New Journal of Chemistry, Volume 47, Issue 10, Pages 4931 – 49436.
VEGA project 1/0145/20
Novel antineoplastic metal-based complexes with mitochondrial activity
Director:Jindra Valentová, doc. PhD.
Vice-director: Natalia Miklášová, PhD.
VIII.a - Name of the institution | VIII.b - Address of the institution | VIII.c - Duration (indicate the duration of stay) | VIII.d - Mobility scheme, employment contract, other (describe) |
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Univerzita Komenského v Bratislave, Prírodovedecká fakulta, Katedra organickej chémie | Bratislava, Slovakia | 2 months (2000) | CEEPUS štipendium |
University of Bath, Department of Chemistry | Bath, Veľká Británia | 1 month (2002) | Študijný pobyt |
Univerzita v Pecs, Lekárska fakulta, Katedra Biochémie a Medicinálnej chémie | Pecs, Maďarsko | 1 month (2002) | CEEPUS štipendium |
Univerzita v Lipsku, Fakulta chémie a mineralógie, Katedra anorganickej chémie | Leipzig, Germany | 1 year (2003-2004) | Marie Curie štipendium |
Laboratory Techniques and Syntheses in Organic Chemistry, Natalia Miklášová, Ladislav Habala Lucia Lintnerová, prvé vydanie 2022