Name and surname:
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doc. Mgr. Ľuboš Molčan, PhD.
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Document type:
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Research/art/teacher profile of a person
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The name of the university:
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Comenius University Bratislava
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The seat of the university:
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Šafárikovo námestie 6, 818 06 Bratislava
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III.a - Occupation-position | III.b - Institution | III.c - Duration |
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associate professor | Comenius University in Bratislava, Faculty of Natural Science | 2021 – present |
assistant professor | Comenius University in Bratislava, Faculty of Natural Science | 2014 – 2021 |
IV.a - Activity description, course name, other | IV.b - Name of the institution | IV.c - Year |
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Training: "Protection of animals used for scientific or educational purposes" | Institute of veterinary training, Košice, Slovakia | 2019 |
Udacity Android Beginner Scholarship (Online internship paid by Google) | Udacity, Emeryville, California, United States | 2017 |
Accredited training of the training program "Protection of animals used for scientific or educational purposes" according to Directive 2010/63 / EU | Institute of veterinary training, Košice, Slovakia | 2015 |
V.1.a - Name of the profile course | V.1.b - Study programme | V.1.c - Degree | V.1.d - Field of study |
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Cell biology | Biology | I. | Biology |
Cell biology | Medical Biology | I. | Biology |
Cell Biology | Biological Chemistry | I. | Biology |
Animal and Human Physiology | Biology | I. | Biology |
Animal and Human Physiology | Medical Biology | I. | Biology |
V.5.a - Name of the course | V.5.b - Study programme | V.5.c - Degree | V.5.d - Field of study |
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Bachelor Thesis in Animal Physiology and Ethology | Biology, Medical Biology | I. | Biology |
Bachelor Dissertation Seminar in Animal Physiology and Ethology (1) | Biology, Medical Biology | I. | Biology |
Bachelor Dissertation Seminar in Animal Physiology and Ethology (2) | Biology, Medical Biology | I. | Biology |
Cell biology | Biology, Systematic biology | I. | Biology |
Animal and Human Physiology | Biology, Systematic biology | I. | Biology |
Human Functional Morphology | Medical biology | I. | Biology |
Integrative Physiology | Animal Physiology and ethology | II. | Biology |
Master Thesis (1) – (4) | Animal Physiology and Ethology | II. | Biology |
Diploma practice | Animal Physiology and Ethology | II. | Biology |
Special seminar (3) | Animal Physiology and Ethology | II. | Biology |
Cardiovascular Physiology | Animal Physiology and Ethology | II. | Biology |
Basics in Pathophysiology | Animal Physiology and Ethology | II. | Biology |
Special Diploma Work Seminar (1) and (2) | Animal Physiology and Ethology | II. | Biology |
Evaluation of Biological Experiments | Animal Physiology and Ethology | II. | Biology |
Cell Signalling | Animal Physiology | III. | Biology |
Molcan, L., Sutovska, H., Okuliarova, M., Senko, T., Krskova, L., & Zeman, M. (2019). Dim light at night attenuates circadian rhythms in the cardiovascular system and suppresses melatonin in rats. Life sciences, 231, 116568.
Svitok, P., Molcan, L., Stebelova, K., Vesela, A., Sedlackova, N., Ujhazy, E., ... & Zeman, M. (2016). Prenatal hypoxia in rats increased blood pressure and sympathetic drive of the adult offspring. Hypertension Research, 39(7), 501-505.
Schepelmann, M., Molcan, L., Uhrova, H., Zeman, M., & Ellinger, I. (2011). The presence and localization of melatonin receptors in the rat aorta. Cellular and molecular neurobiology, 31(8), 1257-1265.
Molcan, L., Babarikova, K., Cvikova, D., Kincelova, N., Kubincova, L., & Mauer Sutovska, H. (2024). Artificial light at night suppresses the day-night cardiovascular variability: evidence from humans and rats. Pflügers Archiv-European Journal of Physiology, 476(3), 295-306.
Sutovska, H., Miklovic, M., & Molcan, L. (2021). Artificial light at night suppresses the expression of Sarco/endoplasmic reticulum Ca2+‐ATPase in the left ventricle of the heart in normotensive and hypertensive rats. Experimental physiology, 106(8), 1762-1771.
Molcan, L., Sutovska, H., Okuliarova, M., Senko, T., Krskova, L., & Zeman, M. (2019). Dim light at night attenuates circadian rhythms in the cardiovascular system and suppresses melatonin in rats. Life sciences, 231, 116568.
Molcan, L., Babarikova, K., Cvikova, D., Kincelova, N., Kubincova, L., & Mauer Sutovska, H. (2024). Artificial light at night suppresses the day-night cardiovascular variability: evidence from humans and rats. Pflügers Archiv-European Journal of Physiology, 476(3), 295-306.
Mauer Sutovska, H., Obermajer, V., Zeman, M., & Molcan, L. (2024). Artificial light at night affects the daily profile of pulse pressure and protein expression in the thoracic aorta of rats. Hypertension Research, 47(7), 1897-1907.
Sutovska, H., Molcan, L., Koprdova, R., Piesova, M., Mach, M., & Zeman, M. (2021). Prenatal hypoxia increases blood pressure in male rat offspring and affects their response to artificial light at night. Journal of developmental origins of health and disease, 12(4), 587-594.
Sutovska, H., Miklovic, M., & Molcan, L. (2021). Artificial light at night suppresses the expression of Sarco/endoplasmic reticulum Ca2+‐ATPase in the left ventricle of the heart in normotensive and hypertensive rats. Experimental physiology, 106(8), 1762-1771.
Svitok, P., Molcan, L., Stebelova, K., Vesela, A., Sedlackova, N., Ujhazy, E., ... & Zeman, M. (2016). Prenatal hypoxia in rats increased blood pressure and sympathetic drive of the adult offspring. Hypertension Research, 39(7), 501-505.
CITATION: Skeffington, K. L., Beck, C., Itani, N., Niu, Y., Shaw, C. J., & Giussani, D. A. (2020). Hypertension programmed in adult hens by isolated effects of developmental hypoxia in ovo. Hypertension, 76(2), 533-544.
Molcan, L., Sutovska, H., Okuliarova, M., Senko, T., Krskova, L., & Zeman, M. (2019). Dim light at night attenuates circadian rhythms in the cardiovascular system and suppresses melatonin in rats. Life sciences, 231, 116568.
CITATION: Fleury, G., Masís‑Vargas, A., & Kalsbeek, A. Metabolic implications of exposure to light at night: lessons from animal and human studies. Obesity. 2020; 28 (1): S18–28.
Molcan, L., Sutovska, H., Okuliarova, M., Senko, T., Krskova, L., & Zeman, M. (2019). Dim light at night attenuates circadian rhythms in the cardiovascular system and suppresses melatonin in rats. Life sciences, 231, 116568.
CITATION: Cardinali, D. P., Brown, G. M., & Pandi-Perumal, S. R. (2021). Chronotherapy. Handbook of clinical neurology, 179, 357-370.
Molcan, L., Sutovska, H., Okuliarova, M., Senko, T., Krskova, L., & Zeman, M. (2019). Dim light at night attenuates circadian rhythms in the cardiovascular system and suppresses melatonin in rats. Life sciences, 231, 116568.
CITATION: Bumgarner, J. R., Walker, W. H., Quintana, D. D., White, R. C., Richmond, A. A., Meléndez-Fernández, O. H., ... & Nelson, R. J. (2023). Acute exposure to artificial light at night alters hippocampal vascular structure in mice. Iscience, 26(7).
Schepelmann, M., Molcan, L., Uhrova, H., Zeman, M., & Ellinger, I. (2011). The presence and localization of melatonin receptors in the rat aorta. Cellular and molecular neurobiology, 31, 1257-1265.
CITATION: Campos, L. A., Cipolla‐Neto, J., & Michelini, L. C. (2013). Melatonin modulates baroreflex control via area postrema. Brain and behavior, 3(2), 171-177.
VEGA 1/0327/24, 2024 - 2027 (principal investigator) Effect of prenatal application of ergothioneine on the heart, blood vessels and kidneys of offspring exposed to hypoxia during intrauterine development. In the project, we are testing the effects of prenatal hypoxia in the later phase of pregnancy on adult offspring, with the experimental groups also testing the antioxidant ergothioneine, which should minimize the action of free oxygen radicals at the level of the fetus. In the project, we focus on both male and female effects.
APVV-21-0223, 2022 - 2026 (co-investigator) Strengthening weakened circadian control of vital functions to prevent civilization diseases (co-investigator). The project investigates more deeply the adverse effects of dimmed light at night on several systems in the body, including the cardiovascular system. An essential part of the project is pharmacological and non-pharmacological time-of-day interventions to strengthen circadian variability and mitigate the adverse effects of dim light at night.
APVV - 17-0178, 2018 –2022 - Consequences of the circadian disruption by artificial light at night on physiological and behavioral processes (co-investigator). The project addresses the negative effects of light contamination on physiological processes regulating the cardiovascular and immune systems in laboratory mammals and analyzes melatonin levels as a suitable indicator of light pollution
VEGA 1/0492/19, 2019 –2022 Desynchronization of circadian rhythms in selected animal models of diseases of civilization (co-investigator). The project addresses the consequences of disruption of circadian rhythms at the central and peripheral level, especially in terms of metabolic disorders such as diabetes and obesity.
/ APVV-18-0174. Výskum cirkadiánneho potenciálu fasádnych systémov budov (co-investigator). The proposed research will pave the way for the introduction of a completely new evaluation parameter for building facade systems. Criteria of the circadian potential of facade systems exclude unsuitable solutions, especially in areas intended for long-term residence of people, especially in medical and school buildings. The submitted project will thus contribute to the prevention of diseases and the protection of public health.
VII.a - Activity, position | VII.b - Name of the institution, board | VII.c - Duration |
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Member of Slovak Physiological Society and Slovak Medical Association | Slovak Medical Association, Bratislava, Slovakia | since 2013 |
VIII.a - Name of the institution | VIII.b - Address of the institution | VIII.c - Duration (indicate the duration of stay) | VIII.d - Mobility scheme, employment contract, other (describe) |
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Institute for Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University Vienna | Medical University Vienna, Austria | 1.10.2011-31.1.2012 | Ernst-Mach scholarship |
I have created a free web application for students and researchers to analyze oscillating data. It is available at https://cosinor.online. A preprint is also published for the application: "Molcan, L. (2019) Time distributed data analysis by Cosinor. Online application. bioRxiv, 805960, https://doi.org/10.1101/805960".