Name and surname:
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Mgr. Mária Mrvová Garajová, PhD.
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Document type:
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Research/art/teacher profile of a person
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The name of the university:
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Comenius University Bratislava
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The seat of the university:
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Šafárikovo námestie 6, 818 06 Bratislava
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III.a - Occupation-position | III.b - Institution | III.c - Duration |
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researcher | Faculty of Natural Sciences, Comenius University in Bratislava | since 2016 |
researcher | Science Park, Comenius University in Bratislava | 2014 - 2015 |
IV.a - Activity description, course name, other | IV.b - Name of the institution | IV.c - Year |
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English - State Language Exam, C1 | 1SJS Language School in Bratislava | 2017 |
V.1.a - Name of the profile course | V.1.b - Study programme | V.1.c - Degree | V.1.d - Field of study |
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Anatomy and morphology of animals | Systematic Biology | I. | Biology |
Phylogeny and system of invertebrates 1 | Systematic Biology | I. | Biology |
V.5.a - Name of the course | V.5.b - Study programme | V.5.c - Degree | V.5.d - Field of study |
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Parasitic Protists | Biology, Systematic Biology | I. | Biology |
Bachelor Thesis in Zoology 1, 2 | Biology, Systematic Biology | I. | Biology |
Diploma Thesis 1–4 | Zoology | II. | Biology |
Anatomy and morphology of animals | Biology | I. | Biology |
Basics of anatomy and morphology of animals | Teacher Training for Biology in Combination | I. | Teacher Training and Education Science |
ADC: Mrva, M., Garajová, M., Lukáč, M., Ondriska, F. 2011. Weak cytotoxic activity of miltefosine against clinical isolates of Acanthamoeba spp. Journal of Parasitology 97: 538-540.
ADC: Lukáč, M., M. Garajová, M. Mrva, M.Bukovský, F. Ondriska, E. Máriássy, F. Devínsky & I. Lacko. 2012. Relationship between aggregation properties and antimicrobial activities of alkylphosphocholines with branched alkyl chains. International Journal of Pharmaceutics 423: 247-256.
ADC: Garajová, M., Mrva, M., Timko, L., Lukáč, M., Ondriska, F. 2014: Cytomorphological changes and susceptibility of clinical isolates of Acanthamoeba spp. to heterocyclic alkylphosphocholines. Experimental Parasitology 145: S102-S110.
ADC: Lukáč, M., Mrva, M., Garajová, M., Mojžišová, G., Varinská, L., Mojžiš, J., Sabol, M., Kubincová, J., Haragová, H., Ondriska, F., Devínsky, F. 2013: Synthesis, self-aggregation and biological properties of alkylphosphocholine and alkylphosphohomocholine derivatives of cetyltrimethylammonium bromide, cetylpyridinium bromide, benzalkonium bromide (C16) and benzethonium chloride. European Journal of Medicinal Chemistry 66: 46-55.
ADC: Garajová, M., Mrva, M., Vaškovicová, N., Martinka, M., Melicherová, J., Valigurová A. 2019: Cellulose fibrils formation and organisation of cytoskeleton during encystment are essential for Acanthamoeba cyst wall architecture. Scientific Reports 9:4466. doi.org/10.1038/s41598-019-41084-6.
ADC: Mrva M., Malíková L., Garajová M. 2024: Plants of family Lamiaceae as a source of therapeutic agents against Acanthamoeba infections. Memórias do Instituto Oswaldo Cruz 119: e240171. doi:10.1590/0074-02760240171.
ADC: Borovičková, T., Mrva, M., Garajová, M. 2019: Thecamoeba quadrilineata (Amoebozoa, Lobosa) as a new member of amphizoic amoebae – first isolation from endozoic conditions. Parasitology Research 118: 1019-1023.
ADC: Bittner Fialová, S., Kello, M., Čoma, M., Slobodníková, L., Drobná, E., Holková, I., Garajová, M., Mrva, M., Zachar, V., Lukáč, M. 2019: Derivatization of rosmarinic acid enhances its in vitro antitumor, antimicrobial and antiprotozoal properties. Molecules 24, 1078. doi:10.3390/molecules24061078.
ADC: Garajová, M., Mrva, M., Vaškovicová, N., Martinka, M., Melicherová, J., Valigurová A. 2019: Cellulose fibrils formation and organisation of cytoskeleton during encystment are essential for Acanthamoeba cyst wall architecture. Scientific Reports 9:4466. doi.org/10.1038/s41598-019-41084-6.
ADC: Dušeková, A., Garajová, M., Lukáč, M., Mrva, M. 2021: Derivatisation of metronidazole enhances cytotoxic effect against Acanthamoeba genotype T4 isolates and leads to cytomorphological changes in trophozoites. Acta Tropica 2016:105830. doi.org/10.1016/j.actatropica.2021.105830.
Output: Garajová, M., Mrva, M., Vaškovicová, N., Martinka, M., Melicherová, J., Valigurová A. 2019: Cellulose fibrils formation and organisation of cytoskeleton during encystment are essential for Acanthamoeba cyst wall architecture. Scientific Reports 9:4466. citation: [o1] 2019 Anwar, A. - Khan, N.A. - Siddiqui, R.: Plos Neglected Tropical Diseases, Vol. 13, No. 7, 2019, Art. No. e0007385 - SCI
Output: Garajová, M., Mrva, M., Vaškovicová, N., Martinka, M., Melicherová, J., Valigurová A. 2019: Cellulose fibrils formation and organisation of cytoskeleton during encystment are essential for Acanthamoeba cyst wall architecture. Scientific Reports 9:4466. citation: [o1] 2019 Siddiqui, R. - Roberts, S.K. - Ong, T.Y.Y. - Mungroo, M.R. - Anwar, A. - Khan, N.A.: Parasites and Vectors, Vol.12, No. 1, 2019, Art. No. 538 - SCI
Output Mrva, M., Garajová, M. 2018: The efficiency of cultivation media in recovering naked lobose amoebae from freshwater environments. Zoological Studies 57: 9. citation: [o1] 2019 Samba-Louaka, A. - Delafont, V. - Rodier, M.H. - Cateau, E. - Hechard, Y.: FEMS Microbiology Reviews, Vol. 43, No. 4, 2019, s. 415-434 - SCI
Output: Timko, L., Fischer-Fodor, E., Garajová, M., Mrva, M., Chereches, G., Ondriska, F., Bukovský, M., Lukáč, M., Karlovská, J., Kubincová, J., Devínsky, F. 2015: Synthesis of structural analogues of hexadecylphosphocholine and their antineoplastic, antimicrobial and amoebicidal activity. European Journal of Medicinal Chemistry 93: 263-273. citation: [o1] 2017 Stewardson, A. - Johnson, D.: Miltefosine. In: Kucers the Use of Antibiotics: A Clinical Review of Antibacterial, Antifungal, Antiparasitic, and Antiviral Drugs, Seventh Edition. New York : CRC Press, 2017, S. 3292-3309
Output: Timko, L., Fischer-Fodor, E., Garajová, M., Mrva, M., Chereches, G., Ondriska, F., Bukovský, M., Lukáč, M., Karlovská, J., Kubincová, J., Devínsky, F. 2015: Synthesis of structural analogues of hexadecylphosphocholine and their antineoplastic, antimicrobial and amoebicidal activity. European Journal of Medicinal Chemistry 93: 263-273. citation: [o1] 2018 Jeffries, B. - Wang, Z. - Graton, J. - Holland, S.D. - Brind, T. - Greenwood, R.D.R. - Le Questel, J.-Y. - Scott, J.S. - Chiarparin, E. - Linclau, B.: Journal of Medicinal Chemistry, Vol. 61, No. 23, 2018, s. 10602-10618 - SCI
Parasitologically important amphizoic amoebae and new strategies for their elimination. APVV-19-0056. Years of realization: 2020-2024. Co-investigator.
Parasitologically Significant Soil Amoebae: Identification of Host Relationships, Phenotypic Plasticity, Cytomorphological Variability and New Strategies for their Elimination. VEGA 1/0389/19. Years of realization: 2019-2022. Principal investigator.
Medically important amphizoic amoebae and new strategies for their elimination. APVV-15-123. Years of realization: 2016-2020. Co-investigator.
Cytotoxic effect of potentially amoebicidal compounds on parasitologically important soil amphizoic amoebae - causative agents of serious animal infections. VEGA 1/0365/16. Years of realization: 2016-2019. Co-investigator.
VII.a - Activity, position | VII.b - Name of the institution, board | VII.c - Duration |
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member of scientific society | Slovak Society for Parasitology |
VIII.a - Name of the institution | VIII.b - Address of the institution | VIII.c - Duration (indicate the duration of stay) | VIII.d - Mobility scheme, employment contract, other (describe) |
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Department of parasitology, Institute of Botany and Zoology, Faculty of Natural Sciences Masaryk University in Brno | Department of parasitology, Institute of Botany and Zoology, Faculty of Natural Sciences Masaryk University in Brno | June-July 2014 and September 2015 | research stay |