Research/art/teacher profile of a person
Name and surname:
doc. Mgr. Andrej Ficek, PhD.
Document type:
Research/art/teacher profile of a person
The name of the university:
Comenius University Bratislava
The seat of the university:
Šafárikovo námestie 6, 818 06 Bratislava

I. - Basic information

I.1 - Surname
Ficek
I.2 - Name
Andrej
I.3 - Degrees
Mgr., PhD.
I.4 - Year of birth
1977
I.5 - Name of the workplace
Department of Molecular Biology, Faculty of Natural Sciences, Comenius University in Bratislava
I.6 - Address of the workplace
Ilkovičova 6, 842 15 Bratislava
I.7 - Position
associate professor
I.8 - E-mail address
andrej.ficek@uniba.sk
I.9 - Hyperlink to the entry of a person in the Register of university staff
https://www.portalvs.sk/regzam/detail/4227
I.10 - Name of the study field in which a person works at the university
Biology
I.11 - ORCID iD
0000-0001-7526-2361

II. - Higher education and further qualification growth

II.1 - First degree of higher education
II.2 - Second degree of higher education
II.a - Name of the university or institution
Comenius University in Bratislava, Faculty of Natural Sciences
II.b - Year
2000
II.c - Study field and programme
Biology, Molecular Biolology
II.3 - Third degree of higher education
II.a - Name of the university or institution
Comenius University in Bratislava, Faculty of Natural Sciences
II.b - Year
2008
II.c - Study field and programme
Molecular Biology
II.4 - Associate professor
II.a - Name of the university or institution
Comenius University in Bratislava, Faculty of Natural Sciences
II.b - Year
2022
II.c - Study field and programme
Molecular biology
II.5 - Professor
II.6 - Doctor of Science (DrSc.)

III. - Current and previous employment

III.a - Occupation-position III.b - Institution III.c - Duration
associate professor Comenius University in Bratislava, Faculty of Natural Sciences 2022-present
assistant professor Comenius University in Bratislava, Faculty of Natural Sciences 2003 - 2021

IV. - Development of pedagogical, professional, language, digital and other skills

V. - Overview of activities within the teaching career at the university

V.1 - Overview of the profile courses taught in the current academic year according to study programmes
V.1.a - Name of the profile course V.1.b - Study programme V.1.c - Degree V.1.d - Field of study
Human Genetics Biológia/Medicínska biológia I. Biology
Human Molecular Genetics Molecular Biology II. Biology
Advanced DNA Analysis Methods in the Identification and Typisation of Organisms Molecular Biology II. Biology
Biotechnology and Biomedicine Molecular Biology II. Biotechnology
V.2 - Overview of the responsibility for the delivery, development and quality assurance of the study programme or its part at the university in the current academic year
V.2.a - Name of the study programme V.2.b - Degree V.2.c - Field of study
Molecular biology II. Biology
Molecular biology III. Biology
V.3 - Overview of the responsibility for the development and quality of the field of habilitation procedure and inaugural procedure in the current academic year
V.3.a - Name of the field of habilitation procedure and inaugural procedure V.3.b - Study field to which it is assigned
Molecular biology Molecular biology
V.4 - Overview of supervised final theses
V.4.1 - Number of currently supervised theses
V.4.a - Bachelor's (first degree)
4
V.4.b - Diploma (second degree)
4
V.4.c - Dissertation (third degree)
1
V.4.2 - Number of defended theses
V.4.a - Bachelor's (first degree)
26
V.4.b - Diploma (second degree)
17
V.4.c - Dissertation (third degree)
0
V.5 - Overview of other courses taught in the current academic year according to study programmes
V.5.a - Name of the course V.5.b - Study programme V.5.c - Degree V.5.d - Field of study
Seminar on human genetics Molecular Biology II. Biology
Human Genomics Molecular Biology II. Biology
Practical course in human genetics Biology I. Biology

VI. - Overview of the research/artistic/other outputs

VI.1 - Overview of the research/artistic/other outputs and the corresponding citations
VI.1.1 - Number of the research/artistic/other outputs
VI.1.a - Overall
40
VI.1.b - Over the last six years
12
VI.1.2 - Number of the research/artistic/other outputs registered in the Web of Science or Scopus databases
VI.1.a - Overall
40
VI.1.b - Over the last six years
12
VI.1.3 - Number of citations corresponding to the research/artistic/other outputs
VI.1.a - Overall
756
VI.1.b - Over the last six years
316
VI.1.4 - Number of citations registered in the Web of Science or Scopus databases
VI.1.a - Overall
756
VI.1.b - Over the last six years
316
VI.1.5 - Number of invited lectures at the international, national level
VI.1.a - Overall
0
VI.1.b - Over the last six years
0
VI.2 - The most significant research/artistic/other outputs
1

Medova V, Hulinkova I, Laiferova N, Urdova V, Ciznar P, Dolnikova D, Krasnanova V, Fabri O, Ficek A, Soltysova A. The importance of defining the age-specific TREC/KREC levels for detection of various inborn errors of immunity in pediatric and adult patients. Clin Immunol. 2022 Dec;245:109155. doi: 10.1016/j.clim.2022.109155. Epub 2022 Oct 13. PMID: 36243346.

2

Krivoňáková N, Šoltýsová A, Tamáš M, Takáč Z, Krahulec J, Ficek A, Gál M, Gall M, Fehér M, Krivjanská A, Horáková I, Belišová N, Bímová P, Škulcová AB, Mackuľak T. Mathematical modeling based on RT-qPCR analysis of SARS-CoV-2 in wastewater as a tool for epidemiology. Sci Rep. 2021 Sep 30;11(1):19456. doi: 10.1038/s41598-021-98653-x. PMID: 34593871; PMCID: PMC8484274.

3

Etzler J, Peyrl A, Zatkova A, Schildhaus HU, Ficek A, Merkelbach-Bruse S, Kratz CP, Attarbaschi A, Hainfellner JA, Yao S, Messiaen L, Slavc I, Wimmer K. RNA-based mutation analysis identifies an unusual MSH6 splicing defect and circumvents PMS2 pseudogene interference. Hum Mutat. 2008 Feb;29(2):299-305. doi: 10.1002/humu.20657. PMID: 18030674.

4

Minárik G, Ferák V, Feráková E, Ficek A, Poláková H, Kádasi L. High frequency of GJB2 mutation W24X among Slovak Romany (Gypsy) patients with non-syndromic hearing loss (NSHL). Gen Physiol Biophys. 2003 Dec;22(4):549-56. PMID: 15113126.

5

Dusinská M, Ficek A, Horská A, Raslová K, Petrovská H, Vallová B, Drlicková M, Wood SG, Stupáková A, Gasparovic J, Bobek P, Nagyová A, Kováciková Z, Blazícek P, Liegebel U, Collins AR. Glutathione S-transferase polymorphisms influence the level of oxidative DNA damage and antioxidant protection in humans. Mutat Res. 2001 Oct 1;482(1-2):47-55. doi: 10.1016/s0027-5107(01)00209-3. PMID: 11535248.

VI.3 - The most significant research/artistic/other outputs over the last six years
1

Medova V, Hulinkova I, Laiferova N, Urdova V, Ciznar P, Dolnikova D, Krasnanova V, Fabri O, Ficek A, Soltysova A. The importance of defining the age-specific TREC/KREC levels for detection of various inborn errors of immunity in pediatric and adult patients. Clin Immunol. 2022 Dec;245:109155. doi: 10.1016/j.clim.2022.109155. Epub 2022 Oct 13. PMID: 36243346.

2

Lundy L, Fatta-Kassinos D, Slobodnik J, Karaolia P, Cirka L, Kreuzinger N, Castiglioni S, Bijlsma L, Dulio V, Deviller G, Lai FY, Alygizakis N, Barneo M, Baz-Lomba JA, Béen F, Cíchová M, Conde-Pérez K, Covaci A, Donner E, Ficek A, Hassard F, Hedström A, Hernandez F, Janská V, Jellison K, Hofman J, Hill K, Hong PY, Kasprzyk-Hordern B, Kolarević S, Krahulec J, Lambropoulou D, de Llanos R, Mackuľak T, Martinez-García L, Martínez F, Medema G, Micsinai A, Myrmel M, Nasser M, Niederstätter H, Nozal L, Oberacher H, Očenášková V, Ogorzaly L, Papadopoulos D, Peinado B, Pitkänen T, Poza M, Rumbo-Feal S, Sánchez MB, Székely AJ, Soltysova A, Thomaidis NS, Vallejo J, van Nuijs A, Ware V, Viklander M. Making Waves: Collaboration in the time of SARS-CoV-2 - rapid development of an international co-operation and wastewater surveillance database to support public health decision-making. Water Res. 2021 Jul 1;199:117167. doi: 10.1016/j.watres.2021.117167. Epub 2021 Apr 22. PMID: 34015748; PMCID: PMC8060897.

3

Kluckova D, Kolnikova M, Lacinova L, Jurkovicova-Tarabova B, Foltan T, Demko V, Kadasi L, Ficek A, Soltysova A. A Study among the Genotype, Functional Alternations, and Phenotype of 9 SCN1A Mutations in Epilepsy Patients. Sci Rep. 2020 Jun 24;10(1):10288. doi: 10.1038/s41598-020-67215-y. PMID: 32581296; PMCID: PMC7314844.

4

Zahradníková, E., Ficek, A., Brejová, B., Vinař, T., & Mičieta, K. (2020). Mosaicism in old trees and its patterns. Trees, 34(2), 357-370.

5

Budiš J, Kucharík M, Ďuriš F, Gazdarica J, Zrubcová M, Ficek A, Szemes T, Brejová B, Radvanszky J. Dante: genotyping of known complex and expanded short tandem repeats. Bioinformatics. 2019 Apr 15;35(8):1310-1317. doi: 10.1093/bioinformatics/bty791. PMID: 30203023.

VI.4 - The most significant citations corresponding to the research/artistic/other outputs
1

Polak, E., Ficek, A., Radvanszky, J., Soltysova, A., Urge, O., Cmelova, E., ... & Kadasi, L. (2013). Phenylalanine hydroxylase deficiency in the Slovak population: Genotype–phenotype correlations and genotype-based predictions of BH4-responsiveness. Gene, 526(2), 347-355. : Blau, N. Genetics of Phenylketonuria: Then and Now (2016) Human Mutation, 37 (6), pp. 508-515. 

2

Radvansky, J., Ficek, A., & Kadasi, L. (2011). Upgrading molecular diagnostics of myotonic dystrophies: multiplexing for simultaneous characterization of the DMPK and ZNF9 repeat motifs. Molecular and Cellular Probes, 25(4), 182-185. Yum, K., Wang, E.T., Kalsotra, A. Myotonic dystrophy: disease repeat range, penetrance, age of onset, and relationship between repeat size and phenotypes (2017) Current Opinion in Genetics and Development, 44, pp. 30-37. 

3

Etzler, J., Peyrl, A., Zatkova, A., Schildhaus, H. U., Ficek, A., Merkelbach‐Bruse, S., ... & Wimmer, K. (2008). RNA‐based mutation analysis identifies an unusual MSH6 splicing defect and circumvents PMS2 pseudogene interference. Human mutation, 29(2), 299-305.: Ripperger, T., Schlegelberger, B. Acute lymphoblastic leukemia and lymphoma in the context of constitutional mismatch repair deficiency syndrome (2016) European Journal of Medical Genetics, 59 (3), pp. 133-142. 

4

Kluckova, D., Kolnikova, M., Lacinova, L., Jurkovicova-Tarabova, B., Foltan, T., Demko, V., ... & Soltysova, A. (2020). A study among the genotype, functional alternations, and phenotype of 9 SCN1A mutations in epilepsy patients. Scientific Reports, 10(1), 1-13.: Meisler, M.H., Hill, S.F., Yu, W. Sodium channelopathies in neurodevelopmental disorders (2021) Nature Reviews Neuroscience, 22 (3), pp. 152-166. 

5

Soltysova, A., Tothova Tarova, E., Ficek, A., Baldovic, M., Polakova, H., Kayserova, H., & Kadasi, L. (2018). Comprehensive genetic study of cystic fibrosis in Slovak patients in 25 years of genetic diagnostics. The Clinical Respiratory Journal, 12(3), 1197-1206.: Scotet, V., L’hostis, C., Férec, C. The changing epidemiology of cystic fibrosis: Incidence, survival and impact of the CFTRGene discovery (2020) Genes, 11 (6), art. no. 589, .

VI.5 - Participation in conducting (leading) the most important research projects or art projects over the last six years
1

VEGA 1/0190/19 Identifikácia genetických determinantov vrodených porúch imunity. Principal investigator

2

VEGA 1/0434/24 Možnosti epigenetickej modulácie pomocou CRISPR/Cas9 pri štúdiu génov s významnou úlohou v získanej chemorezistencii.

3

APVV-23-0294 Cielená modulácia chromatínovej štruktúry v liečbe malígneho melanómu uvey so zlou prognózou.

4

APVV-21-0197 Preprogramovanie mikroprostredia duktálneho adenokarcinómu pankreasu voči imunoterapii.

VII. - Overview of organizational experience related to higher education and research/artistic/other activities

VIII. - Overview of international mobilities and visits oriented on education and research/artistic/other activities in the given field of study

IX. - Other relevant facts

Date of last update
2022-02-27