Name and surname:
|
RNDr. Jaroslav Blaško, PhD.
|
Document type:
|
Research/art/teacher profile of a person
|
The name of the university:
|
Comenius University Bratislava
|
The seat of the university:
|
Šafárikovo námestie 6, 818 06 Bratislava
|
III.a - Occupation-position | III.b - Institution | III.c - Duration |
---|---|---|
researcher | Comenius University, Faculty of Natural Sciences | 01.10.2007 - 31.08.2022 |
researcher | Comenius University in Bratislava | 01.06.2016 - 30.06.2017 |
assistant professor | Comenius University, Faculty of Natural Sciences | 01.09.2022 - current |
IV.a - Activity description, course name, other | IV.b - Name of the institution | IV.c - Year |
---|---|---|
European Computer Driving Licence | The Slovak society for informatics | 2006 |
training cycle for the preparation of European Union projects | Slovak Academic Information Agency | 2006 |
workshop of comprehensive separation methods | Charles University, Faculty of Science | 2012 |
V.1.a - Name of the profile course | V.1.b - Study programme | V.1.c - Degree | V.1.d - Field of study |
---|---|---|---|
Mass spectrometry in analytical chemistry | Analytical Chemistry | II. | Chemistry |
Gas chromatography | Analytical Chemistry | II. | Chemistry |
Advanced methods on chemometry | Analytical Chemistry | II. | Chemistry |
V.5.a - Name of the course | V.5.b - Study programme | V.5.c - Degree | V.5.d - Field of study |
---|---|---|---|
Seminar in Analytical Chemistry for Biologists | Biology, Medical Biology | I. | Biology |
Analytical Chemistry Practicals for Biologists | Biology, Medical Biology | I. | Biology |
Seminar in Separation Methods | Chemistry | I. | Chemistry |
Chemistry of Atmosphere | Analytical chemistry | II. | Chemistry |
Diploma thesis 1, 2 | Analytical chemistry | II. | Chemistry |
Advanced Seminar in Analytical Chemistry 1, 2 | Analytical chemistry | II. | Chemistry |
Molecular Spectroscopy | Chemistry | I. | Chemistry |
Separation Methods | Chemistry | I. | Chemistry |
Seasonal variations in fatty acid composition of pasture forage plants and CLA content in ewe milk fat. Meľuchová B.; Blaško J.; Kubinec R.; Górová R.; Dúbravská J.; Margetín M.; Soják L., Small Ruminant Research 2008, 78 (1-3), 56-65. (2007: 2,106 - IF; Q2 - JCR, Q2 - SJR), citácie/citations: 73
Determination of phthalate sum in fatty food by gas chromatography. Ostrovský, I.; Čabala R.; Kubinec R.; Górová R.; Blaško J.; Kubincová J.; Řimnáčová L.; Lorenz W. Food Chemistry 2011, 124, 392-395. (2010: 3.458 - IF; Q1 – JCR, Q1 – SJR), citácie/citations: 44
Gas chromatography analysis of benzene, toluene, ethylbenzene and xylenes using newly designed needle trap device in aqueous samples. Jurdáková H.; Kubinec R.; Jurčišinová M.; Krkošová Z.; Blaško J.; Ostrovský I.; Soják L.; Berezkin V.G. Journal of Chromatography A 2008, 1194 (2), 161 – 164. (2007: 3,641 - IF; Q1 – JCR, Q1 – SJR), citácie/citations: 64
The complex mechanism of antimycobacterial action of 5-fluorouracil. Singh V.; Brecík M.; Mukherjee R.; Evans J.C.; Svetlíková Z.; Blaško J.; Surade S.; Blackburn J.; Warner D.F.; Mikušová K.; Mizrahi V. Chemistry and Biology 2015, 22 (1), 63-75. (2014: 6,645 - IF; Q1 – JCR, - - SJR), citácie/citations: 60
Chemometric deconvolution of gas chromatographic unresolved conjugated linoleic acid isomers triplet in milk samples. Blaško J.; Kubinec R.; Ostrovský I.; Pavlíková E.; Krupčík J.; Soják L. Journal of Chromatography A 2009, 1216 (14), 2757-2761. (2008: 3,756 - IF; Q1 – JCR, Q1 – SJR), citácie/citations: 18
Analysis of volatile organic compounds in the breath of patients with stable or acute exacerbation of chronic obstructive pulmonary disease. Pizzini A.; Filipiak W.; Wille, J.; Ager, C.; Wiesenhofer, H.; Kubinec, R.; Blaško, J.; Tschurtschenthaler, C.; Mayhew, C.A.; Weiss, G.; Bellmann-Weiler, R. Journal of Breath Research 2018, 12 (3), 036002. (2017: 3.489 – IF; Q2 - JCR, Q1 - SJR ), citácie/citations: 49
Simultaneous analysis of carbohydrates, polyols and amines in urine samples using chemical ionization gas chromatography with tandem mass spectrometry. Kubinec R.; Kotora P.; Ferenczy V.; Blaško J.; Podolec P.; Hengerics Szabó A.; Behúlová D.; Bierhanzl, V.; Čabala R.; Stuchlík S.; Filipiak W.; Thang N.M. Journal of Separation Science 2018, 41 (2), 449-458. (2017: 2.415 - IF; Q2 - JCR, Q2 - SJR ), citácie/citations: 12
The antifungal activity of vapour phase of odourless thymol derivate. Kubinec R.; Blaško J.; Galbavá P.; Jurdaková H.; Sadecká J.; Pangallo D.; Bučková M.; Puškarová A. PeerJ 2000, 8 an 9601. (2019: 2.379 - IF; Q2 - JCR, Q1 - SJR ), citácie/citations: 1
Catalytic hydroprocessing of camelina oil/AGO mixtures over NiMoP/γ-Al2O3 catalysts. Slezáčková, M., Peller, A., Mikulec, J., Banič, M., Blaško, J., Hájeková, E. Catalysis Today, 2023, 423, no. 113953 (2022: 5.3 - IF; Q1 - JCR, Q1 - SJR ), citácie/citations: 0
Newly Synthesized Thymol Derivative and Its Effect on Colorectal Cancer Cells. Blazickova, M.; Blasko, J.; Kubinec, R.; Kozics, K. Molecules 2022, 27 (9), 2622 (2021: 4.927 - IF; Q2 - JCR, Q1 - SJR), citácie/citations: 5
Blaško J., Kubinec R., Ostrovský I., Pavlíková E., Krupčík J., Soják L.. Chemometric deconvolution of gas chromatographic unresolved conjugated linoleic acid isomers triplet in milk samples. Journal of Chromatography A 2009, 1216 (14), 2757-2761. Citácia/citation: De La Fuente M.A., Juárez M. - Conjugated linoleic acid ( Book Chapter), Handbook of Analysis of Active Compounds in Functional Foods 2012 pp. 747-767.
Singh V., Brecik M., Mukherjee R., Evans J.C., Svetlikova Z., Blasko J., Surade S., (...), Mizrahi V. The complex mechanism of antimycobacterial action of 5-fluorouracil Chemistry and Biology, 2015 1 63-75. Citácia/citation: Johnson E.O., LaVerriere E., Office E., Stanley M., Meyer E., Kawate T., Gomez J.E., Audette R.E., Bandyopadhyay N., Betancourt N., Delano K., Da Silva I. Nature 2019, 571 (7763), 72-78.
Ostrovský I., Čabala R., Kubinec R., Górová R., Blaško J., Kubincová J., Řimnáčová L., Lorenz W. Determination of phthalate sum in fatty food by gas chromatography. Food Chemistry 2011, 124, 392-395. Citácia/citation: Yang J., Li Y., Wang Y., Ruan J., Zhang J., Sun C. Recent advances in analysis of phthalate esters in foods. TrAC - Trends in Analytical Chemistry 2015, 72, 10-26.
Mori G., Chiarelli L.R., Esposito M., Makarov V., Bellinzoni M., Hartkoorn R.C., Degiacomi G., Boldrin F., Ekins S., De jesus lopes ribeiro A.L., Marino L.B., Centarova I., Svetlikova Z., Blasko J., Kazakova E., Lepioshkin A., Barilone N., Zanoni G., Porta A., Fondi M, Fani R., Baulard A.R., Mikusova K., Alzari P.M., Manganelli R., De carvalho L.P.S., Riccardi G., Cole S.T., Pasca M.R. Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG. Chemistry and Biology 2015, 7, 917-927. Citácia/citation: Coll F., Phelan J., Hill-Cawthorne G.A., Nair M.B., Mallard K., Ali S., Abdallah A.M., Alghamdi S., Alsomali M., Ahmed A.O., Portelli S., Oppong Y. Nature Genetics 2018, 50 (2), 307-316.
Pizzini A.; Filipiak W.; Wille, J.; Ager, C.; Wiesenhofer, H.; Kubinec, R.; Blaško, J.; Tschurtschenthaler, C.; Mayhew, C.A.; Weiss, G.; Bellmann-Weiler, R. Analysis of volatile organic compounds in the breath of patients with stable or acute exacerbation of chronic obstructive pulmonary disease. Journal of Breath Research 2018, 12 (3), 036002. Citácia/citation: Trivedi D.K., Sinclair E., Xu Y., Sarkar D., Walton-Doyle C., Liscio C., Banks P., Milne J., Silverdale M., Kunath T., Goodacre R., Barran P. Discovery of Volatile Biomarkers of Parkinson's Disease from Sebum. ACS Central Science 2019, 5 (4), 599 - 606.
APVV-18-0282 - Development of preparative chromatography new configurations for 2-deoxysaccharides preparation (2019 - 2023, principal investigator). The proposed project concerned on to development of new procedures for reaction mixtures purification and optimization of synthesis of fluoro- and azido- derivatives of 2-deoxysacharides. A new separation system consists of tandem elution and displacement preparative chromatography will be developed, which will minimize the necessary isolation costs and allows to obtain pure isomers of selected 2-deoxysaccharides in the high purity and with a significantly higher effectivity. The solution of the problem could be optimization of reaction conditions in attempt to obtain more preferable ratio of epimers which have appropriate properties for effective separation using new developed preparative chromatographic systems. Expected project results strengthen the international position of chemical research and production of chemical specialties in Slovakia.
APVV-15-0466 - Preparation of natural flavors by biotransformation using the comprehensive analytical methods. (2019 - 2023, investigator). As part of the project solution, comprehensive analytical methods were developed that enable the analysis of all relevant parameters needed to monitor the process of natural flavours biotransformation. New technologies have also been developed, enabling the extraction of natural flavours from the medium after biotransformation with significant energy savings and at lower temperatures than previously used technologies. The utility model has been assigned to these technologies and a patent application has been filed. Biotransfor- mations of acetophenone to 1-phenylethanol were performed in a two-enzyme system. Using newly developed comprehensive analytical methods, the results of biotransformation were determined, at 87% conversion, the final product represented up to 99.9% of the desired S-isomer of 1-phenylethanol, which confirms the high enantiospecific bioconversion.
APVV-18-0255 - Catalytic depolymerization of lignin from raw materials for the production of advanced biofuels (2019-2022, investigator). Advanced biofuels are utilizing biomass feedstock that has no high economic value except being utilized as biofuel. This fact ensures high greenhouse gas (GHG) savings with only little risk of changing indirect land-use. They do not compete directly with any agricultural land intended for food and feed markets. The main objective of the project is to develop a profitable and economically efficient technological process of processing the secondary stream from the production of bioethanol from cellulosic biomass of lignin by the process of combining the process of solvolysis, hydrocracking and hydrotreating in the presence of mixed oxide catalysts. Lignin decomposition to bio-aromatics and/or high-octane components in fuels. Testing properties of prepared bio-components and determining the emission profile of fuels.
APVV-15-0515 - Topological aspects of mycobacterial arabinogalactan biosynthesis (2016-2020, investigator). The cell envelope of Mycobacterium tuberculosis serves as a primary protective barrier of the pathogen, which claims more than a million lives each year. Its basis, the unique mycobacterial cell wall core, branched heteropolysaccharide arabinogalactan and mycolic acids. Based on our data
we proposed a model for coupled synthesis and export of the galactan polymer precursor in mycobacteria providing an important new insight into biogenesis of a structure critical for the pathogen survival. Novel methodologies developed during this project will be applied in our further efforts to elucidate aspects of mycobacterial cell wall biogenesis.
APVV-20-0317 - Research and development of new recovery processes of volatile aroma compounds from biotechnological broth (2021-2025), investigator). The goal of this project is the development of a profitable and environmentally friendly process in line with green chemistry guidelines allowing the production and isolation of aromatic substances from biotechnological broth. To achieve this goal a combination of industrially established and emerging separation techniques will be used. The chosen techniques are selective, compatible and their combination ensures both high purity and maximal recovery of aromatic substances. This combination minimises the use of distillation techniques, what brings about reduced energy consumption and elimination of thermal load, thus preventing product decomposition. The separation process is mainly built around colloidal milling, nanofiltration and adsorption. In parallel, comprehensive analytical techniques will be developed to decipher complex matrices and enable reliable identification and quantification of natural aroma compounds at every step of the process. During the initial phase laboratory research will be conducted. The findings will then be implemented on production scale. An adjustable device will be created to facilitate the isolation of aroma molecules from highly complex biotechnological broth, which is extremely challenging and at times outright impossible by standard techniques. This device will not only allow monitoring at every stage of the process, but also permit quick adjustments of parameters when and where it is necessary.
VII.a - Activity, position | VII.b - Name of the institution, board | VII.c - Duration |
---|---|---|
member of Slovak chemical society | Slovak chemical society | since 2008 |
VIII.a - Name of the institution | VIII.b - Address of the institution | VIII.c - Duration (indicate the duration of stay) | VIII.d - Mobility scheme, employment contract, other (describe) |
---|---|---|---|
Department of Analytical Chemistry, Charles University in Prague, Faculty of Science, Prag, Czech Republic | Hlavova 2030/8, CZ-128 43 Prague 2 | 1 month/ 2013 | Erasmus |
Institute for Analytics and Environmental Chemistry , Faculty of Natural Sciences, Martin-Luther-Universität Halle-Wittenberg | Kurt-Mothes 3, DE-06120 Halle (Saale) | 1 month/ 2006 | recenzent pre časopisy Scientific Reports, European Journal of Lipid Science and Technology, Small Ruminat Research, Chemical Papers / reviewer for the journals: Scientific Reports, European Journal of Lipid Science and Technology, Small Ruminat Research, Chemical Papers project 54/04-I/32-DP, ITMS: 13120110048 |
reviewer for the journals: Scientific Reports, European Journal of Lipid Science and Technology, Small Ruminat Research, Chemical Papers