Name and surname:
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doc. MUDr. RNDr. Lukáš Varga, PhD.
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Document type:
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Research/art/teacher profile of a person
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The name of the university:
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Comenius University Bratislava
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The seat of the university:
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Šafárikovo námestie 6, 818 06 Bratislava
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III.a - Occupation-position | III.b - Institution | III.c - Duration |
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associate professor | Comenius University, Faculty of Medicine | 2022 - until now |
researcher | Slovak Academy of Sciences, Biomedical Research Center | 2011 - until now |
physician, ENT specialist | University Hospital Bratislava | 2009 - until now |
assistant professor | Comenius University, Faculty of Medicine | 2009-2022 |
assistant | Comenius University, Faculty of Natural Sciences | 2007-2009 |
IV.a - Activity description, course name, other | IV.b - Name of the institution | IV.c - Year |
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Politzer Society certified Human Temporal Bone Dissection Course | Graduate School of Medicine, Kyoto University, Japan | 2014 |
Bioinformatics Workshop | Welcome Trust Sanger Institute, Hinxton, Cambridge, UK | 2011 |
Observership | Ear Institute, Royal National Throat, Nose and Ear Hospital, University College London, UK | 2017 |
Instructor for international TBL and hearing implant courses | MED-EL, Innsbruck, Austria; Faculty of Medicine, Comenius University, Bratislava, Slovakia | 2019 - until now |
V.1.a - Name of the profile course | V.1.b - Study programme | V.1.c - Degree | V.1.d - Field of study |
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Otorhinolaryngology | General medicine | I.+II. | General Medicine |
Otorhinolaryngology | Dentistry | I.+II. | Dentistry, Dental Medicine |
V.2.a - Name of the study programme | V.2.b - Degree | V.2.c - Field of study |
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Otorhinolaryngology | III. | General Medicine |
Medical Neuroscience | III. | General Medicine |
Balaz M, Becker AS, Balazova L, Straub L, Müller J, Gashi G, Maushart CI, Sun W, Dong H, Moser C, Horvath C, Efthymiou V, Rachamin Y, Modica S, Zellweger C, Bacanovic S, Stefanicka P, Varga L, Ukropcova B, Profant M, Opitz L, Amri EZ, Akula MK, Bergo M, Ukropec J, Falk C, Zamboni N, Betz MJ, Burger IA, Wolfrum C. Inhibition of Mevalonate Pathway Prevents Adipocyte Browning in Mice and Men by Affecting Protein Prenylation. Cell Metab. 2019;29(4):901-916.
Mašindová I, Šoltýsová A, Varga L, Mátyás P, Ficek A, Hučková M, Sůrová M, Šafka-Brožková D, Anwar S, Bene J, Straka S, Janicsek I, Ahmed ZM, Seeman P, Melegh B, Profant M, Klimeš I, Riazuddin S, Kádasi Ľ, Gašperíková D. MARVELD2 (DFNB49) mutations in the hearing impaired Central European Roma population--prevalence, clinical impact and the common origin. PLoS One. 2015;10(4):e0124232.
Nayak G, Varga L, Trincot C, Shahzad M, Friedman PL, Klimes I, Greinwald JH Jr, Riazuddin SA, Masindova I, Profant M, Khan SN, Friedman TB, Ahmed ZM, Gasperikova D, Riazuddin S, Riazuddin S. Molecular genetics of MARVELD2 and clinical phenotype in Pakistani and Slovak families segregating DFNB49 hearing loss. Hum Genet. 2015 Apr;134(4):423-37.
Varga L, Mašindová I, Hučková M, Kabátová Z, Gašperíková D, Klimeš I, Profant M. Prevalence of DFNB1 mutations among cochlear implant users in Slovakia and its clinical implications. Eur Arch Otorhinolaryngol. 2014;271(6):1401-7
Perdikari A, Leparc GG, Balaz M, Pires ND, Lidell ME, Sun W, Fernandez-Albert F, Müller S, Akchiche N, Dong H, Balazova L, Opitz L, Röder E, Klein H, Stefanicka P, Varga L, Nuutila P, Virtanen KA, Niemi T, Taittonen M, Rudofsky G, Ukropec J, Enerbäck S, Stupka E, Neubauer H, Wolfrum C. BATLAS: Deconvoluting Brown Adipose Tissue. Cell Rep. 2018 Oct 16;25(3):784-797.e4. doi: 10.1016/j.celrep.2018.09.044.
Pavlenkova Z, Varga L, Borecka S, Karhanek M, Huckova M, Skopkova M, Profant M, Gasperikova D. Comprehensive molecular-genetic analysis of mid-frequency sensorineural hearing loss. Sci Rep. 2021 Nov 18;11(1):22488. doi: 10.1038/s41598-021-01876-1.
Varga L, Danis D, Drsata J, Masindova I, Skopkova M, Slobodova Z, Chrobok V, Profant M, Gasperikova D. Novel variants in EDNRB gene in Waardenburg syndrome type II and SOX10 gene in PCWH syndrome. Int J Pediatr Otorhinolaryngol. 2021 Jan;140:110499. doi: 10.1016/j.ijporl.2020.110499.
Safka Brozkova D, Varga L, Uhrova Meszarosova A, Slobodova Z, Skopkova M, Soltysova A, Ficek A, Jencik J, Lastuvkova J, Gasperikova D, Seeman P. Variant c.2158-2A>G in MANBA is an important and frequent cause of hereditary hearing loss and beta-mannosidosis among the Czech and Slovak Roma population- evidence for a new ethnic-specific variant. Orphanet J Rare Dis. 2020 Aug 26;15(1):222. doi: 10.1186/s13023-020-01508-3.
Kovaničová Z, Kurdiová T, Baláž M, Štefanička P, Varga L, Kulterer OC, Betz MJ, Haug AR, Burger IA, Kiefer FW, Wolfrum C, Ukropcová B, Ukropec J. Cold Exposure Distinctively Modulates Parathyroid and Thyroid Hormones in Cold-Acclimatized and Non-Acclimatized Humans. Endocrinology. 2020 Jul 1;161(7):bqaa051. doi: 10.1210/endocr/bqaa051.
Safka Brozkova D, Uhrova Meszarosova A, Lassuthova P, Varga L, Staněk D, Borecká S, Laštůvková J, Čejnová V, Rašková D, Lhota F, Gašperíková D, Seeman P. The Cause of Hereditary Hearing Loss in GJB2 Heterozygotes-A Comprehensive Study of the GJB2/DFNB1 Region. Genes (Basel). 2021 May 1;12(5):684. doi: 10.3390/genes12050684.
Varga L et al . Is deafness etiology important for prediction of functional outcomes in pediatric cochlear implantation? Acta Otolaryngol. 2014, cited by: .Abdurehim Y et al. State the output and Predictive Value of GJB2 Mutation Status for Hearing Outcomes of Pediatric Cochlear Implantation. Otolaryngol Head Neck Surg. 2017;157(1):16-24
Perdikari A et al. BATLAS: Deconvoluting Brown Adipose Tissue. Cell Rep. 2018, cited by: Kutyavin VI, Chawla A. BCL6 regulates brown adipocyte dormancy to maintain thermogenic reserve and fitness. Proc Natl Acad Sci U S A. 2019;116(34):17071-17080.
Varga L et al . Novel EYA4 variant in Slovak family with late onset autosomal dominant hearing loss: a case report. BMC Med Genet. 2019, cited by: Putscher E et al . Principles and Practical Considerations for the Analysis of Disease-Associated Alternative Splicing Events Using the Gateway Cloning-Based Minigene Vectors pDESTsplice and pSpliceExpress. Int J Mol Sci. 2021;22(10):5154.
Balaz M et al. Inhibition of Mevalonate Pathway Prevents Adipocyte Browning in Mice and Men by Affecting Protein Prenylation. Cell Metab. 2019, cited by: Sveidahl Johansen O et al. : Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis. Cell. 2021;184(13):3502-3518.e33.
Mašindová I, Šoltýsová A, Varga L et al .: MARVELD2 (DFNB49) mutations in the hearing impaired Central European Roma population--prevalence, clinical impactand the common origin. PLoS One. 2015;10(4):e0124232,cited by: Naz S. Molecular genetic landscape of hereditary hearing loss in Pakistan. Hum Genet. 2021; doi: 10.1007/s00439-021-02320-0
VII.a - Activity, position | VII.b - Name of the institution, board | VII.c - Duration |
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Academic Senate Member | Comenius University, Faculty of Medicine | 2015 - until now |
Faculty member for Board exam in ENT | Comenius University, Faculty of Medicine | 2018 - until now |
Faculty member for Board exam in Phoniatry | Comenius University, Faculty of Medicine | 2021 - until now |
Honorary Member | Danube Society of the Otorhinolaryngology - Head and Neck Surgery | 2019 |
member | European Academy of Otology & Neuro - Otology (EAONO) | 2021 - until now |