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Name and surname:
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prof. RNDr. Vanda Repiská, PhD., MPH
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Document type:
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Research/art/teacher profile of a person
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The name of the university:
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Comenius University Bratislava
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The seat of the university:
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Šafárikovo námestie 6, 818 06 Bratislava
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| III.a - Occupation-position | III.b - Institution | III.c - Duration |
|---|---|---|
| university teacher - Full Professor and Deputy Head of the Institute | Institute of Medical Biology, Genetics and Clinical Genetics, faculty of Medicine, Comenius University in Bratislava | 2005 - until now |
| university teacher - Assistant Professor | Institute of Medical Biology, Genetics and Clinical Genetics, Faculty of Medicine, Comenius University in Bratislava | 1998 - 2005 |
| researcher | Institute of Medical Biology, Genetics and Clinical Genetics, Faculty of Medicine, Comenius University in Bratislava | 1993 - 1998 |
| maternity leave | maternity leave | 1991 - 1993 |
| researcher | Department of Molecular Biology and Genetics, Faculty of Natural Sciences, Comenius University in Bratislava | 1990-1991 |
| IV.a - Activity description, course name, other | IV.b - Name of the institution | IV.c - Year |
|---|---|---|
| Hybrid capture | Bratislava, Medirex group academy | 2003 |
| Multiplex PCR Course | TATAA Biocenter AB, Göteborg, Sweden | 2015 |
| MPH | European Business & Management Institute | 2023 |
| V.1.a - Name of the profile course | V.1.b - Study programme | V.1.c - Degree | V.1.d - Field of study |
|---|---|---|---|
| Biology and Human Genetics I | General Medicine | I.+II. | General Medicine |
| Biology and Human Genetics II | General Medicine | I.+II. | General Medicine |
| Biology and Human Genetics I | Dentistry | I.+II. | General Medicine |
| Biology and Human Genetics II | Dentistry | I.+II. | General Medicine |
| Medical Biology | Biomedical Physics | I.+II. | Physics |
| Molecular Biology | Biomedical Physics | I.+II. | Physics |
| New trends in medical biology and clinical genetics | medical biology and clinical genetics | III. | General Medicine |
| V.2.a - Name of the study programme | V.2.b - Degree | V.2.c - Field of study |
|---|---|---|
| General Medicine | III. | Medical biology and clinical genetics-Garant |
| General Medicine | III. | Tutor of PhD. Students in Anatomy, Histology and Embryology |
| General Medicine | III. | Tutor of PhD. Students in Patological Anatomy and Forensic Medicine |
| General Medicine | III. | Tutor of PhD. Students in Normal and Pathological Physiology |
| Biology and Human Genetics I | I.+II. | Dentistry- garant |
| Biology and Human Genetics II | I.+II. | Dentistry- garant |
| V.5.a - Name of the course | V.5.b - Study programme | V.5.c - Degree | V.5.d - Field of study |
|---|---|---|---|
| Biology and human genetics 1-garant | dentistry | I.+II. | general medicine |
| Biology and human genetics 2-garant | dentistry | I.+II. | general medicine |
| New trends in medical biology and clinical genetics-Garant | Medical biology and clinical genetics | III. | General medicine |
Wang CM, Dixon PH, Decordova S, Hodges MD, Sebire NJ, Ozalp S, Fallahian M, Sensi A, Ashrafi F, Repiska V, Zhao J, Xiang Y, Savage PM, Seckl MJ, Fisher RA. Identification of 13 novel NLRP7 mutations in 20 families with recurrent hydatidiform mole; missense mutations cluster in the leucine-rich region. J Med Genet. 2009 Aug;46(8):569-75. doi: 10.1136/jmg.2008.064196.
Fridrichova I, Smolkova B, Kajabova V, Zmetakova I, Krivulcik T, Mego M, Cierna Z, Karaba M, Benca J, Pindak D, Bohac M, Repiska V, Danihel L. CXCL12 and ADAM23 hypermethylation are associated with advanced breast cancers. Transl Res. 2015 Jun;165(6):717-30. doi: 10.1016/j.trsl.2014.12.006
Altanerova U, Jakubechova J, Benejova K, Priscakova P, Pesta M, Pitule P, Topolcan O, Kausitz J, Zduriencikova M, Repiska V, Altaner C. Prodrug suicide gene therapy for cancer targeted intracellular by mesenchymal stem cell exosomes. Int J Cancer. 2019 Feb 15;144(4):897-908. doi: 10.1002/ijc.31792.
Altanerova U, Jakubechova J, Benejova K, Priscakova P, Repiska V, Babelova A, Smolkova B, Altaner C. Intracellular prodrug gene therapy for cancer mediated by tumor cell suicide gene exosomes. Int J Cancer. 2021 Jan 1;148(1):128-139. doi: 10.1002/ijc.33188.
Bľandová G, Janoštiaková N, Kodada D, Pastorek M, Lipták R, Hodosy J, Šebeková K, Celec P, Krasňanská G, Eliaš V, Wachsmannová L, Konečný M, Repiská V, Baldovič M. Mitochondrial DNA variability and Covid-19 in the Slovak population. Mitochondrion. 2024 Mar;75:101827. doi: 10.1016/j.mito.2023.101827.
Klimova D, Jakubechova J, Altanerova U, Nicodemou A, Styk J, Szemes T, Repiska V, Altaner C. Extracellular vesicles derived from dental mesenchymal stem/stromal cells with gemcitabine as a cargo have an inhibitory effect on the growth of pancreatic carcinoma cell lines in vitro. Mol Cell Probes. 2023 Feb;67:101894. doi: 10.1016/j.mcp.2023.101894.
Altanerova U, Jakubechova J, Benejova K, Priscakova P, Repiska V, Babelova A, Smolkova B, Altaner C. Intracellular prodrug gene therapy for cancer mediated by tumor cell suicide gene exosomes. Int J Cancer. 2021 Jan 1;148(1):128-139. doi: 10.1002/ijc.33188.
Priščáková P, Svoboda M, Feketová Z, Hutník J, Repiská V, Gbelcová H, Gergely L. Syncytin-1, syncytin-2 and suppressyn in human health and disease. J Mol Med (Berl). 2023 Dec;101(12):1527-1542. doi: 10.1007/s00109-023-02385-6.
Bľandová G, Janoštiaková N, Kodada D, Pastorek M, Lipták R, Hodosy J, Šebeková K, Celec P, Krasňanská G, Eliaš V, Wachsmannová L, Konečný M, Repiská V, Baldovič M. Mitochondrial DNA variability and Covid-19 in the Slovak population. Mitochondrion. 2024 Mar;75:101827. doi: 10.1016/j.mito.2023.101827.
Kodada D, Hadžega D, Krumpolec P, Janoštiaková N, Bľandová G, Janega P, Ballová Z, Dosedla E, Minárik G, Repiská V. Differential gene expression in uterine endometrioid cancer cells and adjusted normal tissue. Mol Cell Probes. 2025 Jun;81:102027. doi: 10.1016/j.mcp.2025.102027.
Zheng D, Liwinski T, Elinav E. Inflammasome activation and regulation: toward a better understanding of complex mechanisms. Cell Discov. 2020 Jun 9;6:36. doi: 10.1038/s41421-020-0167-x. – references a paper: Wang CM, Dixon PH, Decordova S, Hodges MD, Sebire NJ, Ozalp S, Fallahian M, Sensi A, Ashrafi F, Repiska V, Zhao J, Xiang Y, Savage PM, Seckl MJ, Fisher RA. Identification of 13 novel NLRP7 mutations in 20 families with recurrent hydatidiform mole; missense mutations cluster in the leucine-rich region. J Med Genet. 2009 Aug;46(8):569-75. doi: 10.1136/jmg.2008.064196.
Kim SY, Khanal D, Kalionis B, Chrzanowski W. High-fidelity probing of the structure and heterogeneity of extracellular vesicles by resonance-enhanced atomic force microscopy infrared spectroscopy. Nat Protoc. 2019 Feb;14(2):576-593. doi: 10.1038/s41596-018-0109-3. - references a paper: Stanko P, Altanerova U, Jakubechova J, Repiska V, Altaner C. Dental Mesenchymal Stem/Stromal Cells and Their Exosomes. Stem Cells Int. 2018 Apr 15;2018:8973613. doi: 10.1155/2018/8973613
Docherty LE, Rezwan FI, Poole RL, Turner CL, Kivuva E, Maher ER, Smithson SF, Hamilton-Shield JP, Patalan M, Gizewska M, Peregud-Pogorzelski J, Beygo J, Buiting K, Horsthemke B, Soellner L, Begemann M, Eggermann T, Baple E, Mansour S, Temple IK, Mackay DJ. Mutations in NLRP5 are associated with reproductive wastage and multilocus imprinting disorders in humans. Nat Commun. 2015 Sep 1;6:8086. doi: 10.1038/ncomms9086. – references a paper: Wang CM, Dixon PH, Decordova S, Hodges MD, Sebire NJ, Ozalp S, Fallahian M, Sensi A, Ashrafi F, Repiska V, Zhao J, Xiang Y, Savage PM, Seckl MJ, Fisher RA. Identification of 13 novel NLRP7 mutations in 20 families with recurrent hydatidiform mole; missense mutations cluster in the leucine-rich region. J Med Genet. 2009 Aug;46(8):569-75. doi: 10.1136/jmg.2008.064196.
Bibby JA, Purvis HA, Hayday T, Chandra A, Okkenhaug K, Rosenzweig S, Aksentijevich I, Wood M, Lachmann HJ, Kemper C, Cope AP, Perucha E. Cholesterol metabolism drives regulatory B cell IL-10 through provision of geranylgeranyl pyrophosphate. Nat Commun. 2020 Jul 8;11(1):3412. doi: 10.1038/s41467-020-17179-4. – references a paper: Gbelcová H, Rimpelová S, Knejzlík Z, Šáchová J, Kolář M, Strnad H, Repiská V, D'Acunto WC, Ruml T, Vítek L. Isoprenoids responsible for protein prenylation modulate the biological effects of statins on pancreatic cancer cells. Lipids Health Dis. 2017 Dec 20;16(1):250. doi: 10.1186/s12944-017-0641-0.
Shek J, Sun C, Wilson EM, Moadab F, Hastie KM, Rajamanickam RR, Penalosa PJ, Harkins SS, Parekh D, Hariharan C, Zyla DS, Yu C, Shaffer KCL, Lewis VI, Avalos RD, Mustelin T, Saphire EO. Human endogenous retrovirus K (HERV-K) envelope structures in pre- and postfusion by cryo-EM. Sci Adv. 2025 Aug 29;11(35):eady8168. doi: 10.1126/sciadv.ady8168. – references a paper: Priščáková P, Svoboda M, Feketová Z, Hutník J, Repiská V, Gbelcová H, Gergely L. Syncytin-1, syncytin-2 and suppressyn in human health and disease. J Mol Med (Berl). 2023 Dec;101(12):1527-1542. doi: 10.1007/s00109-023-02385-6.
APVV-17-0382 -2022) Interaction of cold plasma with water, the effects of plasma activated water to biological, systems and their uses in medicine and agriculture (2018 - 2022)
OP Integrated Infrastructure for the project: Long term strategic research and development focused on the occurrence of Lynch syndrome in the Slovak population and possibilities of prevention of tumors associated with this syndrome, ITMS: 313011V578, co-financed by the European Regional Development Fund. 01/2020 - 12/2023
MZSR 2018/40-LKUK-14 - SYNCYTÍN-1 as a new marker for pre-eclampsia, the second leading cause of death in pregnant women (2018 –2021)
VEGA 1/0198/24 Genetic causes of intrauterine fetal death 1/2024-12/2027
EATRIS - coordinator LFUK 1/2025
| VII.a - Activity, position | VII.b - Name of the institution, board | VII.c - Duration |
|---|---|---|
| Creation of questions for admissions | Faculty of medicine | 2024 |
| Innovation in biology teaching | Faculty of medicine | 2024 |
| Preparatory course | Faculty of medicine | 2007-2025 |
| Translational mitochondrial medicine. | Bratislava, Herba | 2024 |
| Biology booklet for entrance examination. | UK Bratislava | 2024, 2025, 2026 |
| Formation of biomacromolecules and their role in the transmission of genetic information | Faculty of medicine LF UK | 207-2011 |
| Genetic aspects of diabetic retinopathy | Faculty of medicine LF UK | 2016 |
| Genetic basis of orofacial clefts | SAP Bratislava | 2017 |
| Prospective New Technologies of mtDNA Diagnosis | Springer | 2024 |
| New trends in medical biology and clinical genetics | Faculty of medicine LF UK | 2024 |
1.Prize of the Slovak Society of Pathologists for a set of publication about Gestational trophoblastic disease published in 2003
2. Academic commendation and the rector's prize as the leader of an awarded diploma thesis in the academic year 2004/2005 at LFUK
3. Prize of Incheba and the international scientific conference: Current forms and means of education of health workers in the EU following the conclusions of the international conference AMEE 2006. 2nd place in the field of Genetics and Genomics. 2007
4. LFUK dean's prize for 1st place for a set of poster presentations Genetics and Genomics within the IOC Incheba EXPO and international scientific conference, 2007
5. Multiple winner - the most popular LFUK teacher "Guru"
6. Slovak Woman of the Year 2010 in the Science and Education category
7. Academic commendation and the rector's prize as the leader of an awarded diploma thesis in the academic year 2004/2005 at LFUK
8. Academic commendation and rector's prize in the academic year 2012/2013 at LFUK
9. Bronze medal UK 2014
10. Silver medal UK 2017
11. Gold medal on the occasion of 100 years of LFUK