I. - Basic information

I.1 - Surname

Polák

I.2 - Name

Štefan

I.3 - Degrees

Prof., MUDr., CSc.

I.4 - Year of birth

1955

I.5 - Name of the workplace

Institute of Anatomy LFUK

I.6 - Address of the workplace

Sasinkova 2, 1st floor 811 08 Bratislava

I.7 - Position

Head of the Institute

I.8 - E-mail address

stefan.polak@fmed.uniba.sk

I.9 - Hyperlink to the entry of a person in the Register of university staff

https://www.portalvs.sk/regzam/detail/3345?do=filterForm-submit&name=%C5%A0tefan&surname=Pol%C3%A1k&university=701000000&faculty=701010000&employment_state=yes&filter=Vyh%C4%BEada%C5%A5

I.10 - Name of the study field in which a person works at the university

Anatomy, Histology and Embryology

I.11 - ORCID iD

https://orcid.org/0000-0001-7489-1510

II. - Higher education and further qualification growth

II.1 - First degree of higher education

II.2 - Second degree of higher education

II.a - Name of the university or institution

LF UK in Bratislava

II.b - Year

1980

II.c - Study field and programme

General Medicine

II.3 - Third degree of higher education

II.a - Name of the university or institution

LFUK in Bratislava

II.b - Year

1993

II.c - Study field and programme

Pathological anatomy and forensic medicine

II.4 - Associate professor

II.a - Name of the university or institution

LFUK in Bratislava

II.b - Year

2006

II.c - Study field and programme

Anatomy, histology and embryology

II.5 - Professor

II.a - Name of the university or institution

LFUK in Bratislava

II.b - Year

2015

II.c - Study field and programme

Pathological anatomy and forensic medicine

II.6 - Doctor of Science (DrSc.)

III. - Current and previous employment

III.a - Occupation-position	III.b - Institution	III.c - Duration
Assistant professor	Institute of pathology of the faculty hospital of Comenius University in Bratislava	1980 - 1998
Assistant professor	Institute of histology and embryology of Comenius University in Bratislava	1998 - 2005
Associate professor, head of institute	Institute of histology and embryology of Comenius University in Bratislava	2005 - 2015
Full professor, head of institute	Institute of histology and embryology of Comenius University in Bratislava	2015 - 2023
Full professor, head of institute	Institute of anatomy of Comenius University in Bratislava	2023 - present

IV. - Development of pedagogical, professional, language, digital and other skills

IV.a - Activity description, course name, other	IV.b - Name of the institution	IV.c - Year
Board certificate in anatomical pathology 1st. level	National health institute in Bratislava	1985
Board certificate in anatomical pathology	Slovak medical university in Bratislava	2010

V. - Overview of activities within the teaching career at the university

V.1 - Overview of the profile courses taught in the current academic year according to study programmes

V.1.a - Name of the profile course	V.1.b - Study programme	V.1.c - Degree	V.1.d - Field of study
Histology and embryology I, II	General medicine	I.+II.	General medicine
Histology and embryology I, II	Dentistry	I.+II.	Dentistry
Histology and Embryology I, II	General medicine	I.+II.	General medicine
Histology and Embryology I, II	Dentistry	I.+II.	Dentistry
Histology I, II	Biomedical physics	I.	General medicine
Experimental methods in medical physics II	Biomedical physics	II.	General medicine
Anatomy I, II and III	General medicine	I.+II.	General medicine
Anatomy I, II	Dentistry	I.+II.	Dentistiry
Anatomy I, II and III	General medicine	I.+II.	General medicine
Anatomy I, II	Dentistry	I.+II.	Dentistry

V.2 - Overview of the responsibility for the delivery, development and quality assurance of the study programme or its part at the university in the current academic year

V.2.a - Name of the study programme	V.2.b - Degree	V.2.c - Field of study
Supervisor of PhD students in Anatomy, histology and embryology	III.	General medicine
Supervisor of PhD students in pathological anatomy and forensic medicine	III.	General medicine
Garant of histology and embryology	I.+II.	General medicine
Garant of biomedical physics	I.	General medicine
Garant of biomedical physics	II.	General medicine

V.3 - Overview of the responsibility for the development and quality of the field of habilitation procedure and inaugural procedure in the current academic year

V.4 - Overview of supervised final theses

V.4.1 - Number of currently supervised theses

V.4.2 - Number of defended theses

V.4.a - Bachelor's (first degree)

V.4.b - Diploma (second degree)

V.4.c - Dissertation (third degree)

V.5 - Overview of other courses taught in the current academic year according to study programmes

VI. - Overview of the research/artistic/other outputs

VI.1 - Overview of the research/artistic/other outputs and the corresponding citations

VI.1.1 - Number of the research/artistic/other outputs

VI.1.a - Overall

530

VI.1.b - Over the last six years

VI.1.2 - Number of the research/artistic/other outputs registered in the Web of Science or Scopus databases

VI.1.a - Overall

142

VI.1.b - Over the last six years

VI.1.3 - Number of citations corresponding to the research/artistic/other outputs

VI.1.a - Overall

1856

VI.1.b - Over the last six years

347

VI.1.4 - Number of citations registered in the Web of Science or Scopus databases

VI.1.a - Overall

1722

VI.1.b - Over the last six years

346

VI.1.5 - Number of invited lectures at the international, national level

VI.2 - The most significant research/artistic/other outputs

Juríková, M., Danihel, Ľ., Polák, Š., & Varga, I. (2016). Ki67, PCNA, and MCM proteins: Markers of proliferation in the diagnosis of breast cancer. Acta histochemica, 118(5), 544-552.

Danišovič, Ľ., Varga, I., & Polák, Š. (2012). Growth factors and chondrogenic differentiation of mesenchymal stem cells. Tissue and Cell, 44(2), 69-73.

Varga, I., Galfiova, P., Adamkov, M., Danisovic, L., Polak, S., Kubikova, E., & Galbavy, S. (2009). Congenital anomalies of the spleen from an embryological point of view. Med Sci Monit, 15(12), 269-276.

Kucerova, L., Kovacovicova, M., Polak, S., Bohac, M., Fedeles, J., Palencar, D., & Matuskova, M. (2011). Interaction of human adipose tissue-derived mesenchymal stromal cells with breast cancer cells. Neoplasma, 58(5), 361.

Csobonyeiova, M., Polak, S., Zamborsky, R., & Danisovic, L. (2019). Recent progress in the regeneration of spinal cord injuries by induced pluripotent stem cells. International Journal of Molecular Sciences, 20(15), 3838.

VI.3 - The most significant research/artistic/other outputs over the last six years

Thurzo, A., Gálfiová, P., Nováková, Z. V., Polák, Š., Varga, I., Strunga, M., ... & Danišovič, Ľ. (2022). Fabrication and in vitro characterization of novel hydroxyapatite scaffolds 3D printed using polyvinyl alcohol as a thermoplastic binder. International Journal of Molecular Sciences, 23(23), 14870.

Kopani, M., Mikula, M., Kosnac, D., Kovac, J., Trnka, M., Gregus, J.,Jerigova, M, Jergel, M., Vavrinsky, E., Bacova, S., Zitto, P, Polak, S., Pincik, E. (2020). Effect of etching time in hydrofluoric acid on the structure and morphology of n-type porous silicon. Applied Surface Science, 532, 147463.

Hollý, D., Klein, M., Mazreku, M., Zamborský, R., Polák, Š., Danišovič, Ľ., & Csöbönyeiová, M. (2021). Stem Cells and Their Derivatives—Implications for Alveolar Bone Regeneration: A Comprehensive Review. International journal of molecular sciences, 22(21), 11746.

Gaburjáková, M., Gaburjáková, J., Krejčíová, E., Kosnáč, D., Kosnáčová, H., Nagy, Š., ... & Kopáni, M. (2021). Blocking effect of ferritin on the ryanodine receptor-isoform 2. Archives of Biochemistry and Biophysics, 712, 109031.

Csobonyeiova, M., Polak, S., Nicodemou, A., Zamborsky, R., & Danisovic, L. (2021). iPSCs in Modeling and Therapy of Osteoarthritis. Biomedicines, 9(2), 186.

VI.4 - The most significant citations corresponding to the research/artistic/other outputs

Mikušová R, Mešťanová V, Polák Š, Varga I. What do we know about the structure of human thymic

Hassall's corpuscles? A histochemical, immunohistochemical, and electron microscopic study. Annals of

Anatomy. 2017; 211: 140-148.

Cited i:

Yayon N, Kedlian VR, Boehme L, Suo C, Wachter BT, Beuschel RT, Amsalem O, Polanski K, et al. A spatial

human thymus cell atlas mapped to a continuous tissue axis. Nature. 2024 ; 635(8039): 708-718.

Kadouri N, Nevo S, Goldfarb Y, Abramson J. Thymic epithelial cell heterogeneity: TEC by TEC.N ature

Reviews Immunolology. 2020; 20(4): 239-253.

Heimli M, Flåm ST, Hjorthaug HS, Trinh D, Frisk M, Dumont KA, Ribarska T, Tekpli X, Saare M, Lie BA.

Multimodal human thymic profiling reveals trajectories and cellular milieu for T agonist selection. Frontiers

in Immunology. 2023 ; 13: 1092028.

Cited in:

Mills SE (Ed). Histology for Pathologists. Fifth Edition. Wolters Kluwer, Philadelphia. 2020.

Franke D, Anupindi SA, Barnewolt CE, Green TG, Greer MC, et al. Contrast-enhanced ultrasound of the

spleen, pancreas and gallbladder in children. Pediatric Radiology. 2021 ; 51(12): 2229-2252.

Xiao M, Liang J, Ren J, Zheng R, Wu L. The imaging features of ectopic spleen: which modality is more

consistent? A cases series report and literature reviews. Frontiers in Oncology. 2024 ; 14: 1310394.

Cited in:

2024 - Xu, Gang - Ge, Rui - Zhang, Chunli - Zhao, Ziteng - Han, Liwei - Zhang, Wanhao - Yue, Wen Jie - Zhang, Jing - Zhao, Yantao - Hou, Shuxun - Li, Li - Wang, Peng. Promotion of nerve regeneration and motor function recovery in SCI rats using LOCAS-iPSCs-NSCs. DOI 10.1186/s13287-024-03999-4 In: Stem cell research & therapy. Londýn: Springer Nature. BioMed Central, 2024, Roč. 15, č. 1, art. no. 376 [online]. ISSN (online) 1757-6512. - SCO ; WOS CC ; SCIE, s. art. no. 376

2024 - Abbas, Azar - Huang, Xiaosheng - Ullah, Aftab - Luo, Lishi - Xi, Wenqun - Qiao, Yuanjiao - Zeng, Kun. Enhanced spinal cord repair using bioengineered induced pluripotent stem cell-derived exosomes loaded with miRNA. DOI 10.1186/s10020-024-00940-6 In: Molecular Medicine. New York: Springer Nature. Springer Gabler, 2024, Roč. 30, č. 1, art. no. 168 [tlačená forma] [online]. ISSN 1076-1551. ISSN (online) 1528-3658. - SCO ; CCC ; WOS CC ; SCIE, s. art. no. 168

2023 - Marei, Hany E. - Khan, Muhammad Umar Aslam - Hasan, Anwarul. Potential use of iPSCs for disease modeling, drug screening, and cell-based therapy for Alzheimer's disease [elektronický dokument]. DOI 10.1186/s11658-023-00504-2 In: Cellular & Molecular Biology Letters: an international journal. Bazilej: Springer Nature, 2023, Roč. 28, č. 1, art. no. 98, s.. ISSN 1425-8153. ISSN (online) 1689-1392. - WOS CC ; SCO, s. art. no. 98

Svobodová, H., Kosnáč, D., Balázsiová, Z., Tanila, H., Miettinen, P. O., Sierra, A., ... & Kopáni, M. (2019). Elevated Age-Related Cortical Iron, Ferritin and Amyloid Plaques in APPswe/PS1ΔE9 Transgenic Mouse Model of Alzheimer's Disease. Physiological Research, 68, S445-S451.

Cited in:

2024 - Faraji, Parisa - Parandavar, Elham - Kuhn, Hartmut - Habibi-Rezaei, Mehran - Borchert, Astrid - Zahedi, Elham - Ahmadian, Shahin. Oral administration of butylated hydroxytoluene induces neuroprotection in a streptozotocin-induced rat Alzheimer’s disease model via inhibition of neuronal ferroptosis [elektronický dokument]. DOI 10.1186/s10020-024-00980-y In: Molecular Medicine. New York: Springer Nature. Springer Gabler, 2024, Roč. 30, č. 1, art. no. 204 [online]. ISSN 1076-1551. ISSN (online) 1528-3658. - SCO ; CCC ; WOS CC ; SCIE, s. art. no. 204

2024 - Levi, Sonia - Ripamonti, Maddalena - Moro, Andrea Stefano - Cozzi, Anna. Iron imbalance in neurodegeneration . DOI 10.1038/s41380-023-02399-z In: Molecular psychiatry. Houndmills: Springer Nature. Nature Publishing Group, 2024, Roč. 29, č. 4, s. 1139-1152 [online]. ISSN 1359-4184. ISSN (online) 1476-5578. - SCO ; CCC ; WOS CC ; SCIE, s. 1139 - 1152

2023 - Qiu, Z. - Zhang, H. - Xia, M. - Gu, J. - Guo, K. - Wang, H. - Miao, Changhong. Programmed Death of Microglia in Alzheimer’s Disease: Autophagy, Ferroptosis, and Pyroptosis [elektronický dokument]. DOI 10.14283/jpad.2023.3 In: The journal of prevention of Alzheimer's disease. Cham: Springer Nature. Springer International Publishing AG, 2023, Roč. 10, č. 1, s. 95-103 [online]. ISSN 2274-5807. ISSN (online) 2426-0266. - SCO ; WOS CC, s. 95 - 103

Cited in:

2015 Zhang, Tao - Kolonin, Mikhail G. Role of Adipose Cells in Tumor Microenvironment . DOI 10.1007/8415_2013_171 In: The Mechanobiology of Obesity and Related Diseases. Cham: Springer, 2015, s. 271-294 [online]. ISBN 978-3-319-09335-2. ISBN 978-3-319-37626-4. ISBN (online) 978-3-319-09336-9. - SCO, s. 271 - 294

VI.5 - Participation in conducting (leading) the most important research projects or art projects over the last six years

APVV - 18 - 0499 Histomorphological basis of idiopathic tubal sterility. The relation between acquired immunity, lymphatic drainage and telocytes with fallopian tube function. 2019 - 2023 (team member)

KEGA 074UK-4/2019 Scanning electron microscopy atlas of the organ-specific ultrastructure morphology. 2019 - 2022 (team leader)

VEGA 1/0256/24 Clinicopathological correlation of markers of the microenvironment in breast cancer with potential use in target therapy. 2024 - 2027 ( team leader)

VII. - Overview of organizational experience related to higher education and research/artistic/other activities

VII.a - Activity, position	VII.b - Name of the institution, board	VII.c - Duration
Establishing of scanning electron microscopy laboratory in the Institute of pathological anatomy LFUK and UNB	Institute of pathological anatomy LFUK and UNB	1986 - 2010
Creating an educational database of macroscopic autopsy findings in the Institute of pathological anatomy LFUK and UNB	Institute of pathological anatomy LFUK and UNB	1988 - 1998
Establishing a modern centre of electronmicroscopic laboratory techniques in the Institute of histology and embryology LFUK	Institute of histology and embryology LFUK	2015 - present
Modernization of educational methods in the Institute of histology and embryology LFUK	Institute of histology and embryology LFUK	2005 - 2023
Establishing a modern centre of transmission electron microscopy in the Institute of anatomy LFUK	Institute of anatomy LFUK	2024 - present

VIII. - Overview of international mobilities and visits oriented on education and research/artistic/other activities in the given field of study

VIII.a - Name of the institution	VIII.b - Address of the institution	VIII.c - Duration (indicate the duration of stay)	VIII.d - Mobility scheme, employment contract, other (describe)
Opton (Zeiss) Oberkochen	Oberkochen, NSR	1986	mobilities within a research and educational cooperation
IVF centrum	Praha, Brno	Multiple times	Mobilities within a long-term research and educational cooperation

IX. - Other relevant facts

IX.a - If relevant, other activities related to higher education or research/artistic/other activities are mentioned

Member of the scientific senate of the Faculty of Medicine, Comenius University in Bratislava

1985 – Jesennius award of the Slovak Medical Society

1991 – Award of the Slovak Society of Gastroeneterology for best publication

1998 – present: Member of the Scientific Board of the Faculty of Medicine, Comenius University in Bratislava

2010 – The bronze medal of the Comenius University

2015 – The silver medal of the Comenius University

2011 – Award of the Slovak Anatomical Society for best publication

2022 – Award of the Slovak Anatomical Society for best publication

2022 – Medal of the foundation of the Slavic Medical Society

2025 – The gold medal of the Comenius University

Date of last update

2025-04-30

Name and surname:	prof. MUDr. Štefan Polák, CSc.
Document type:	Research/art/teacher profile of a person
The name of the university:	Comenius University Bratislava
The seat of the university:	Šafárikovo námestie 6, 818 06 Bratislava