Research/art/teacher profile of a person
Name and surname:
doc. PharmDr. Zdenko Pirník, PhD.
Document type:
Research/art/teacher profile of a person
The name of the university:
Comenius University Bratislava
The seat of the university:
Šafárikovo námestie 6, 818 06 Bratislava

I. - Basic information

I.1 - Surname
Pirník
I.2 - Name
Zdenko
I.3 - Degrees
Assoc. prof., PharmD., PhD
I.4 - Year of birth
1976
I.5 - Name of the workplace
Comenius University in Bratislava, Faculty of Medicine, Institute of Physiology
I.6 - Address of the workplace
Dekanát LF UK, Špitálska 24, 813 72 Bratislava
I.7 - Position
assistant professor
I.8 - E-mail address
zdenko.pirnik@fmed.uniba.sk
I.9 - Hyperlink to the entry of a person in the Register of university staff
https://www.portalvs.sk/regzam/detail/6151
I.10 - Name of the study field in which a person works at the university
Normal and pathological physiology
I.11 - ORCID iD
0000-0002-0130-7405

II. - Higher education and further qualification growth

II.1 - First degree of higher education
II.2 - Second degree of higher education
II.a - Name of the university or institution
Comenius University in Bratislava, Faculty of Pharmacy
II.b - Year
2000
II.c - Study field and programme
Pharmacy / pharmacy
II.3 - Third degree of higher education
II.a - Name of the university or institution
Comenius University in Bratislava, Faculty of Pharmacy
II.b - Year
2005
II.c - Study field and programme
Pharmacology
II.4 - Associate professor
II.a - Name of the university or institution
Pavol Jozef Šafárik University in Košice, Faculty of Medicine
II.b - Year
2015
II.c - Study field and programme
Pharmacology
II.5 - Professor
II.6 - Doctor of Science (DrSc.)

III. - Current and previous employment

III.a - Occupation-position III.b - Institution III.c - Duration
researcher Institute of Experimental Endocrinology SAS, Bratislava 2000-2009
assistant professor University of Veterinary Medicine and Pharmacy in Košice 2009-2015
associate professor University of Veterinary Medicine and Pharmacy in Košice 2015-2018
assistant professor Comenius University in Bratislava, Faculty of Medicine since 2018

IV. - Development of pedagogical, professional, language, digital and other skills

IV.a - Activity description, course name, other IV.b - Name of the institution IV.c - Year
Rigorosum proceeding in Pharmacy Comenius University in Bratislava, Faculty of Pharmacy 2009
Scientific-qualification degree Iia Slovak Academy of Sciences, Bratislava 2011

V. - Overview of activities within the teaching career at the university

V.1 - Overview of the profile courses taught in the current academic year according to study programmes
V.1.a - Name of the profile course V.1.b - Study programme V.1.c - Degree V.1.d - Field of study
Medical Physiology Dentistry I+II Dentistry
Medical Physiology General Medicine I+II General Medicine
V.2 - Overview of the responsibility for the delivery, development and quality assurance of the study programme or its part at the university in the current academic year
V.3 - Overview of the responsibility for the development and quality of the field of habilitation procedure and inaugural procedure in the current academic year
V.4 - Overview of supervised final theses
V.4.1 - Number of currently supervised theses
V.4.a - Bachelor's (first degree)
0
V.4.b - Diploma (second degree)
1
V.4.c - Dissertation (third degree)
0
V.4.2 - Number of defended theses
V.4.a - Bachelor's (first degree)
1
V.4.b - Diploma (second degree)
25
V.4.c - Dissertation (third degree)
1
V.5 - Overview of other courses taught in the current academic year according to study programmes

VI. - Overview of the research/artistic/other outputs

VI.1 - Overview of the research/artistic/other outputs and the corresponding citations
VI.1.1 - Number of the research/artistic/other outputs
VI.1.a - Overall
160
VI.1.b - Over the last six years
26
VI.1.2 - Number of the research/artistic/other outputs registered in the Web of Science or Scopus databases
VI.1.a - Overall
43 (WoS) / 53 (Scopus)
VI.1.b - Over the last six years
8 (WoS) / 9 (Scopus)
VI.1.3 - Number of citations corresponding to the research/artistic/other outputs
VI.1.a - Overall
637 (WoS) / 557 (Scopus)
VI.1.b - Over the last six years
197 (Scopus)
VI.1.4 - Number of citations registered in the Web of Science or Scopus databases
VI.1.a - Overall
637 (WoS) / 557 (Scopus)
VI.1.b - Over the last six years
197 (Scopus)
VI.1.5 - Number of invited lectures at the international, national level
VI.1.a - Overall
0
VI.1.b - Over the last six years
0
VI.2 - The most significant research/artistic/other outputs
1

PIRNÍK Z, KOLESÁROVÁ M, ŽELEZNÁ B, MALETÍNSKÁ L.: Repeated peripheral administration of lipidized prolactin-releasing peptide analog induces c-fos and FosB expression in neurons of dorsomedial hypothalamic nucleus in male C57 mice. Neurochem Int. 116:77-84, 2018, IF = 3.262

2

FEDOROVÁ M, PERDUKOVÁ D, PIRNÍK Z, FEDÁK V, SUKEL O, SANJEEVIKUMAR P.: Fuzzy System as a Promising Tool for Drugs Selection in Medical Practice. IEEE Access. 6:27294-27301, 2018, IF = 3.557

3

MALETÍNSKÁ L, NAGELOVÁ V, TICHÁ A, ZEMENOVÁ J, PIRNÍK Z, HOLUBOVÁ M, ŠPOLCOVÁ A, MIKULÁŠKOVÁ B, BLECHOVÁ M, SÝKORA D, LACINOVÁ Z, HALUZÍK M, ŽELEZNÁ B, KUNEŠ J.: Novel lipidized analogs of prolactin-releasing peptide have prolonged half-lives and exert anti-obesity effects after peripheral administration. Int J Obes (Lond). 39(6):986-93, 2015, IF = 5.004

4

ŠPOLCOVÁ A, MIKULÁŠKOVÁ B, HOLUBOVÁ M, NAGELOVÁ V, PIRNIK Z, ZEMENOVÁ J, HALUZÍK M, ŽELEZNÁ B, GALAS MC, MALETÍNSKÁ L.: Anorexigenic lipopeptides ameliorate central insulin signaling and attenuate tau phosphorylation in hippocampi of mice with monosodium glutamate-induced obesity. J Alzheimers Dis. 45(3):823-35, 2015, IF = 4.151

5

PIRNÍK Z, SZADVÁRI I, BORBÉLYOVÁ V, TOMOVÁ A: Atered sex differences related to food intake, hedonic preference, and FosB/deltaFosB expression within central neural circuit involved in homeostatic and hedonic food intake regulation in Shank3B mouse model of autism spectrum disorder. Neurochem Int, 181:105895, 2024, IF = 4.4

VI.3 - The most significant research/artistic/other outputs over the last six years
1

PIRNÍK Z, KOŘÍNKOVÁ L, OSACKÁ J, ŽELEZNÁ B, KUNEŠ J, MALETÍNSKÁ L.: Cholecystokinin system is involved in the anorexigenic effect of peripherally applied palmitoylated prolactin-releasing peptide in fasted mice. Physiol Res. 70(4):579-590, 2021, IF = 2.139

2

PRAŽIENKOVÁ V, FUNDA J, PIRNÍK Z, KARNOŠOVÁ A, HRUBÁ L, KOŘÍNKOVÁ L, NEPRAŠOVÁ B, JANOVSKÁ P, BENZCE M, KADLECOVÁ M, BLAHOŠ J, KOPECKÝ J, ŽELEZNÁ B, KUNEŠ J, BARDOVÁ K, MALETÍNSKÁ L.: GPR10 gene deletion in mice increases basal neuronal activity, disturbs insulin sensitivity and alters lipid homeostasis. Gene. 774:145427, 2021, IF = 3.913

3

PIRNÍK Z, SZADVÁRI I, BORBÉLYOVÁ V, TOMOVÁ A: Atered sex differences related to food intake, hedonic preference, and FosB/deltaFosB expression within central neural circuit involved in homeostatic and hedonic food intake regulation in Shank3B mouse model of autism spectrum disorder. Neurochem Int, 181:105895, 2024, IF = 4.4

4

MORGAN A, SHEKHAR N, STRNADOVÁ V, PIRNÍK Z, HAASOVÁ E., KOPECKÝ J., PAČESOVÁ A., ŽELEZNÁ B., KUNEŠ J., BARDOVÁ K., MALETÍNSKÁ L.: Deficiency of GPR10 and NPFFR2 receptors leads to sex-specific prediabetic syndrome and late-onset obesity in mice. Biosci Rep. 44(10): BSR20241103, 2024, IF = 3.8

5

MIHALJ D, BORBELYOVA V, PIRNIK Z, BACOVA Z, OSTATNIKOVA D, BAKOS J. Shank3 Deficiency Results in a Reduction in GABAergic Postsynaptic Puncta in the Olfactory Brain Areas. Neurochem Res. 49(4):1008-1016, 2024, IF = 3.7

VI.4 - The most significant citations corresponding to the research/artistic/other outputs
1

PRAŽIENKOVÁ V, HOLUBOVÁ M, PELANTOVÁ H, BUGÁŇOVÁ M, PIRNÍK Z, MIKULÁŠKOVÁ B, POPELOVÁ A, BLECHOVÁ M, HALUZÍK M, ŽELEZNÁ B, KUZMA M, KUNEŠ J, MALETÍNSKÁ L.: Impact of novel palmitoylated prolactin-releasing peptide analogs on metabolic changes in mice with diet-induced obesity. PLoS One. 12(8):e0183449, 2017, IF = 2.806 / Citation by Alexopoulou F et al: Lipidated PrRP31 metabolites are long acting dual GPR10 and NPFF2 receptor agonists with potent body weight lowering effect, Scientific Reports 12(1)1696, 2022, SCOPUS

2

NAGELOVÁ V, PIRNÍK Z, ZELEZNÁ B, MALETÍNSKÁ L: CART (cocaine- and amphetamine-regulated transcript) peptide specific binding sites in PC12 cells have characteristics of CART peptide receptors. Brain Res. 1547: 16-24, 2014, IF = 2.843 / Citation by JobMO and Kuhar MJ: CART peptide in the nucleus accumbens regulates psychostimulants: Correlations between psychostimulant and CART peptide effects, Neuroscience 348:135-142, 2017, SCOPUS

3

PIRNIK Z, BUNDZIKOVÁ J, HOLUBOVÁ M, PÝCHOVÁ M, FEHRENTZ JA, MARTINEZ J, ZELEZNÁ B, MALETÍNSKÁ L, KISS A.: Ghrelin agonists impact on Fos protein expression in brain areas related to food intake regulation in male C57BL/6 mice. Neurochem Int. 59(6):889-95, 2011, IF = 2.857 / Citation by Kern A et al: Hippocampal Dopamine/DRD1 Signaling Dependent on the Ghrelin Receptor, Cell 163(5):1176-1190, 2015, SCOPUS

4

KISS A., BUNDZIKOVA J., PIRNIK Z., MIKKELSEN J.D.: Different antipsychotics elicit different effects on magnocellular oxytocinergic and vasopressinergic neurons as revealed by Fos immunohistochemistry. J Neurosci Res. 88(3):677-85, 2010, IF = 2.958 / Citation by Romano et al: From autism to eating disorders and more: The role of oxytocin in neuropsychiatric disorders, Frontiers in Neuroscience 9:497, 2016, SCOPUS

5

MATYSKOVÁ R., MALETÍNSKÁ L., MAIXNEROVÁ J., PIRNÍK Z., KISS A., ZELEZNÁ B.: Comparison of the obesity phenotypes related to monosodium glutamate effect on arcuate nucleus and/or the high fat diet feeding in C57BL/6 and NMRI mice. Physiol Res. 57(5):727-34, 2008, IF = 1.653 / Citation by Lopes FNC et al: Antioxidant therapy reverses sympathetic dysfunction, oxidative stress, and hypertension in male hyperadipose rats, Life Sciences 295:120405, 2022, SCOPUS

VI.5 - Participation in conducting (leading) the most important research projects or art projects over the last six years
1

Vplyv aripiprazolu a obohateného prostredia na morfologicko-funkčné zmeny v hipokampe a správanie v animálnom modeli posttraumatickej stresovej poruchy. Spoluriešiteľ, VEGA 2/0050/23, 2023-2025

2

Sex-specific microbiome and genome interactions in the pathogenesis of behavioral and gastrointestinal symptoms in the animal model of autism spectrum disorder. Spoluriešiteľ, APVV-20-0114, 2021-2025

3

Vplyv črevnej mikrobioty získanej od detí s poruchami autistického spektra na správanie v animálnom modeli. Spoluriešiteľ, VEGA 1/0062/21, 2021-2024

4

Vplyv haloperidolu a olanzapínu na neurogenézu a apoptózu v schizofrenickom modeli, Spoluriešiteľ, VEGA 2/0037/19, 2019-2021

5

Úloha urokortínu 2 v regulácii stresovej reakcie, Spoluriešiteľ, VEGA 2/0015/19, 2019-2021

VII. - Overview of organizational experience related to higher education and research/artistic/other activities

VII.a - Activity, position VII.b - Name of the institution, board VII.c - Duration
member of Endocrine Regulations journal board Biomedical Research Center SAS v.v.i., Bratislava since 2021
member of Folia Pharmaceutica Cassoviensia journal board University of Veterinary Medicine and Pharmacy in Košice since 2019
member of Czech Neuropsychopharmacological Society Czech Neuropsychopharmacological Society since 2003
member of Lekarnicke listy journal board Slovac Chamber of Pharmacy, Bratislava 2020-2023

VIII. - Overview of international mobilities and visits oriented on education and research/artistic/other activities in the given field of study

VIII.a - Name of the institution VIII.b - Address of the institution VIII.c - Duration (indicate the duration of stay) VIII.d - Mobility scheme, employment contract, other (describe)
Institute of Organic Chemistry and Biochemistry of the CAS, Prague Flemingovo námestí 542/2, 160 00 Praha 2014-2015 postdoctoral fellowship

IX. - Other relevant facts

Date of last update
2025-01-24