Research/art/teacher profile of a person
Name and surname:
MUDr. RNDr. Ľudovít Paulis, PhD.
Document type:
Research/art/teacher profile of a person
The name of the university:
Comenius University Bratislava
The seat of the university:
Šafárikovo námestie 6, 818 06 Bratislava

I. - Basic information

I.1 - Surname
Paulis, Ľudovít, MUDr. RNDr. PhD.
I.2 - Name
Ľudovít
I.3 - Degrees
MUDr. RNDr. MPH. PhD.
I.4 - Year of birth
1981
I.5 - Name of the workplace
Comenius University Bratislava, Faculty of Medicine, Institute of Pathological Physiology
I.6 - Address of the workplace
Špitálska ulica 24, 813 72 Bratislava, Slovakia
I.7 - Position
University Teacher - Assistant Professor
I.8 - E-mail address
ludovit.paulis@gmail.com
I.9 - Hyperlink to the entry of a person in the Register of university staff
https://www.portalvs.sk/regzam/detail/5359
I.10 - Name of the study field in which a person works at the university
Normal and Pathological Physiology
I.11 - ORCID iD
0000-0003-3834-7395

II. - Higher education and further qualification growth

II.1 - First degree of higher education
II.2 - Second degree of higher education
II.a - Name of the university or institution
Comenius University Bratislava, Faculty of Medicine
II.b - Year
2006
II.c - Study field and programme
General Medicine
II.3 - Third degree of higher education
II.a - Name of the university or institution
Comenius University Bratislava, Faculty of Medicine
II.b - Year
2008
II.c - Study field and programme
Normal and Pathological Physiology
II.4 - Associate professor
II.5 - Professor
II.6 - Doctor of Science (DrSc.)

III. - Current and previous employment

III.a - Occupation-position III.b - Institution III.c - Duration
University Teacher - Assistant Professor Comenius University Bratislava, Faculty of Medicine, Institute of Pathological Physiology 2007 - ongoing
Researcher Slovak Academy of Sciences, Center for Experimental Medicine, Bratislava 2004 - ongoing
CEO Alterras Therapeutics GmbH, Wien 2017 - 2020
Guest Researcher Center for Cardiovascular Medicine, Charite - University Medicine, Berlin 2011 - 2014
EU Researcher, MSCA Fellow Center for Cardiovascular Medicine, Charite - University Medicine, Berlin 2009-2011
Post-doc INSERM U637, Montpellier 2008 - 2009
Researcher Academy of Sciences of the Czech Republic, Institute of Physiology, Prague 2004 - 2005
Project Manager Comenius University Bratislava, Faculty of Medicine, Center for Project Support 2007 - 2008

IV. - Development of pedagogical, professional, language, digital and other skills

IV.a - Activity description, course name, other IV.b - Name of the institution IV.c - Year
Welfare for Animals in Science and Education Institute for Veterinary Medicine Education, Košice 2014, 2018, 2022
Master in Public Health (MPH) Slovak Medical University, Bratislava 2014 - 2017
Qualification degree IIa. Slovak Academy of Sciences Bratislava 2010
RNDr. in Biology Pavol Jozef Safarik University Kosice, Faculty of Natural Sciences 2010
Francúzsky jazyk B2: Certifikát Agropolis, Montpellier 2008
Project management course Institute of Advanced Studies, Bratislava 2007
Master in Physics, specialization Biomedical Physics Comenius University Bratislava, Faculty of Mathematics, Physics and Informatics 1999 - 2004
German C1/C2: General State Exam State Language School, Nitra 2001
Anglický jazyk C1: First Certificate in English British Council, Bratislava 1998

V. - Overview of activities within the teaching career at the university

V.1 - Overview of the profile courses taught in the current academic year according to study programmes
V.1.a - Name of the profile course V.1.b - Study programme V.1.c - Degree V.1.d - Field of study
Pathological Physiology 1 a Pathological Physiology 2 (in Slovak and English language) General Medicine II General Medicine
Pathological Physiology 1 a Pathological Physiology 2 (in Slovak and English language) Dentistry II Dentistry
Dissertation thessis I. a II., Dissertation Exam, Dissertation Defense Normal and Pathological Physiology III General Medicine
V.2 - Overview of the responsibility for the delivery, development and quality assurance of the study programme or its part at the university in the current academic year
V.3 - Overview of the responsibility for the development and quality of the field of habilitation procedure and inaugural procedure in the current academic year
V.4 - Overview of supervised final theses
V.4.1 - Number of currently supervised theses
V.4.a - Bachelor's (first degree)
0
V.4.b - Diploma (second degree)
0
V.4.c - Dissertation (third degree)
1
V.4.2 - Number of defended theses
V.4.a - Bachelor's (first degree)
1
V.4.b - Diploma (second degree)
14
V.4.c - Dissertation (third degree)
1
V.5 - Overview of other courses taught in the current academic year according to study programmes

VI. - Overview of the research/artistic/other outputs

VI.1 - Overview of the research/artistic/other outputs and the corresponding citations
VI.1.1 - Number of the research/artistic/other outputs
VI.1.a - Overall
271
VI.1.b - Over the last six years
40
VI.1.2 - Number of the research/artistic/other outputs registered in the Web of Science or Scopus databases
VI.1.a - Overall
132 WoS
VI.1.b - Over the last six years
22 WoS
VI.1.3 - Number of citations corresponding to the research/artistic/other outputs
VI.1.a - Overall
2736
VI.1.b - Over the last six years
1291
VI.1.4 - Number of citations registered in the Web of Science or Scopus databases
VI.1.a - Overall
2495 WoS / 2736 SCOPUS
VI.1.b - Over the last six years
175 WoS / 1291 SCOPUS
VI.1.5 - Number of invited lectures at the international, national level
VI.1.a - Overall
10
VI.1.b - Over the last six years
0
VI.2 - The most significant research/artistic/other outputs
1
Paulis L, Steckelings UM, Unger T. Key advances in antihypertensive treatment. Nature Rev Cardiol. 2012; 9(5):276-85. IF=10.4
2
Paulis L, Becker ST, Lucht K, Schwengel K, Slavic S, Kaschina E, Thöne-Reineke C, Dahlöf B, Baulmann J, Unger T, Steckelings UM. Direct angiotensin II type 2 receptor stimulation in Nω-nitro-L-arginine-methyl ester-induced hypertension: the effect on pulse wave velocity and aortic remodeling. Hypertension. 2012; 59(2):485-92. IF=6.9
3
Paulis L, Matuskova J, Adamcova M, Pelouch V, Simko J, Krajcirovicova K, Potacova A, Hulin I, Janega P, Pechanova O, Simko F. Regression of left ventricular hypertrophy and aortic remodelling in NO-deficient hypertensive rats: effect of L-arginine and spironolactone. Acta Physiol (Oxf) 2008; 194(1):45-55. IF=2.5
4
Paulis L, Simko F. LA419, a novel nitric oxide donor, prevents cardiac remodeling via the endothelial nitric oxide synthase pathway: NO donors as a means of antiremodeling. Hypertension 2007; 50(6):1009-1111. IF=7.2
5
Simko F, Paulis L. Melatonin as a potential antihypertensive treatment. J Pineal Res 2007; 42(4):319-322. IF=4.1
VI.3 - The most significant research/artistic/other outputs over the last six years
1

Jasenovec T, Radosinska D, Kollarova M, Vrbjar N, Balis P, Trubacova S, Paulis L, Tothova L, Shawkatova I, Radosinska J. Monocrotaline-Induced Pulmonary Arterial Hypertension and Bosentan Treatment in Rats: Focus on Plasma and Erythrocyte Parameters. Pharmaceuticals (Basel) 2022; 15(10):1227. IF=4.6 


2

Simko F, Baka T, Stanko P, Repova K, Krajcirovicova K, Aziriova S, Domenig O, Zorad S, Adamcova M, Paulis L. Sacubitril/Valsartan and Ivabradine Attenuate Left Ventricular Remodelling and Dysfunction in Spontaneously Hypertensive Rats: Different Interactions with the Renin-Angiotensin-Aldosterone System. Biomedicines 2022; 10(8):1844. IF=4.7


3

Kmecova Z, Veteskova J, Lelkova-Zirova K, Bies Pivackova L, Doka G, Malikova E, Paulis L, Krenek P, Klimas J. Disease severity-related alterations of cardiac microRNAs in experimental pulmonary hypertension. J Cell Mol Med. 2020; 24(12):6943-6951. IF=5.3



4

Simko F, Baka T, Poglitsch M, Repova K, Aziriova S, Krajcirovicova K, Zorad S, Adamcova M, Paulis L. Effect of Ivabradine on a Hypertensive Heart and the Renin-Angiotensin-Aldosterone System in L-NAME-Induced Hypertension. Int J Mol Sci 2018; 19(10):3017. IF=5.6

5

Simko F, Baka T, Krajcirovicova K, Repova K, Aziriova S, Zorad S, Poglitsch M, Adamcova M, Reiter RJ, Paulis L. Effect of Melatonin on the Renin-Angiotensin-Aldosterone System in l-NAME-Induced Hypertension. Molecules 2018; 23(2):265. IF=4.6

VI.4 - The most significant citations corresponding to the research/artistic/other outputs
1

Ruilope, LM Current challenges in the clinical management of hypertension. NATURE REVIEWS CARDIOLOGY 9 (5) , pp.267-275 

citing: Paulis L, Unger T. Novel therapeutic targets for hypertension. Nat Rev Cardiol. 2010 Aug;7(8):431-41.

2

Opie, LH and Lecour, S Melatonin has multiorgan effects. EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY 2 (4), pp.258-265 

citing: Simko F, Paulis L. Melatonin as a potential antihypertensive treatment. J Pineal Res. 2007 Apr;42(4):319-22.

3

Cipolla-Neto, J and do Amaral, FG. Melatonin as a Hormone: New Physiological and Clinical Insights. ENDOCRINE REVIEWS 39 (6) , pp.990-1028 

citing: Paulis L, Simko F. Blood pressure modulation and cardiovascular protection by melatonin: potential mechanisms behind. Physiol Res. 2007;56(6):671-684.

4

Ferri, C and Grassi, D. Antioxidants and Beneficial Microvascular Effects Is This the Remedy? HYPERTENSION 55 (6) , pp.1310-1311 

citing: Paulis L, Simko F. Blood pressure modulation and cardiovascular protection by melatonin: potential mechanisms behind. Physiol Res. 2007;56(6):671-684.

5

Foulquier, S; Steckelings, UM and Unger, T. PERSPECTIVE A tale of two receptors. NATURE 493 (7434) , pp.S9-S9 

citing: Paulis L, Becker ST, Lucht K, Schwengel K, Slavic S, Kaschina E, Thöne-Reineke C, Dahlöf B, Baulmann J, Unger T, Steckelings UM. Direct angiotensin II type 2 receptor stimulation in Nomega-nitro-L-arginine-methyl ester-induced hypertension: the effect on pulse wave velocity and aortic remodeling. Hypertension. 2012 Feb;59(2):485-92.

VI.5 - Participation in conducting (leading) the most important research projects or art projects over the last six years
1

APVV-19-0521 Olga Pechanova 2020-2024 The effect of AP/ACE inhibitors associated with nanoparticles on the experimental model of the failing heart

2

VEGA 2/0112/19 Fedor Šimko/Olga Pechanova 2019-2022 Experimental myocardial infarction: the contribution of hypertension and obesity, the effect of toll-like receptor inhibition

3

VEGA 1/0035/19 Fedor Šimko 2019-2022 Protection of the cardiovascular system in experimental hypertension and heart failure by dual inhibition of neprilysin and AT1 receptor for angiotensin II: The comparison with ACE-inhibition and melatonin

4

VEGA 1/0127/17 Ludovit Paulis 2017-2020 Proof of concept of RAS activity modulation by dual aminopeptidase/angiotensin converting enzyme inhibition and the effect on target organ damage in hemodynamic overload

5

VEGA 1/0227/12 Fedor Simko 2012-2016 New model of hypertension, left ventricle remodeling and heart failure induced by NF-kB inhibition: protection by melatonin and captopril

VII. - Overview of organizational experience related to higher education and research/artistic/other activities

VII.a - Activity, position VII.b - Name of the institution, board VII.c - Duration
Scientific council member Slovak Medical University Bratislava 2020 - 2022
Management council member Slovak Technical University 2021 - 2022
Management council member Technical University Kosice 2021 - 2022
Management council member Technical University Zilina 2021 - 2022
Industrial council member Slovak Technical University Bratislava, Faculty of Electronics and Informatics 2022 - ongoing
Fellow European Society of Cardiology 2014 - ongoing
Executive Committee member Slovak Society of Cardiology, Working group on Experimental Cardiology 2018
Executive Committee member European Council on Cardiovascular Research 2010 - 2014, 2016 - 2020
Chair LuPa, o.z. 2011 - ongoing

VIII. - Overview of international mobilities and visits oriented on education and research/artistic/other activities in the given field of study

VIII.a - Name of the institution VIII.b - Address of the institution VIII.c - Duration (indicate the duration of stay) VIII.d - Mobility scheme, employment contract, other (describe)
Center for Cardiovascular Research / Institute for Pharmacology, Charité-University Medicine Berlin, Germany 08/2009-02/2011 Marie Curie Individual Fellowship
INSERM U637 Montpellier, France 03/2007-05/2007 French government stipend
Max-Delbrueck-Centrum for Molecular Medicine Berlin, Germany 06/2005-08/2005 DAAD fellowship

IX. - Other relevant facts

IX.a - If relevant, other activities related to higher education or research/artistic/other activities are mentioned

03/2012 Guothova cena, Slovenská lekárska spoločnosť

05/2011 Čestné uznanie vo výbere vedec roka 2010

12/2010 Najlepší poster v sekcii: Fibrose/Inflammation na 34th Congress of the German Hypertension League (DHL), Berlín

06/2010 Ocenenie pre najlepšieho mladého výskumníka v oblasti Life Science, Slovenská akadémia vied, Bratislava

09/2009 Najlepšia publikácia v oblasti experimentálnej hypertenzie (Paulis et al, Hypertens Res, 2008), o.z. Blood Pressure, Praha

09/2006 Cena Ľudovej banky za vzdelanosť, Bratislava

06/2006 Cena Jiřího Widimského pre mladých vedeckých pracovníkov v oblasti hypertenzie 16th European Society for Hypertension Meeting, Madrid

Managing Editor Frontiers of Bioscience

Oponentúra pre karentované časopisy: Expert Opinion on Investigational Drugs, Hypertension, Journal of Hypertension, Expert Opinion on Drug delivery, Expert Opinion on Pharmacology, Hypertension research, Cardiol Lett, Bratisl. Lek. Listy, Journal of American Society of Hypertension, Physiological research

Oponentúra grantových projektov VEGA

Oponentúra dizertačných prác Lekárska fakulta UK, Macquarie University, Sydney

Date of last update
2024-04-26