Research/art/teacher profile of a person

Name and surname:	MUDr. Zuzana Országhová, PhD.
Document type:	Research/art/teacher profile of a person
The name of the university:	Comenius University Bratislava
The seat of the university:	Šafárikovo námestie 6, 818 06 Bratislava

I. - Basic information

I.1 - Surname

Országhová

I.2 - Name

Zuzana

I.3 - Degrees

M.D.

I.4 - Year of birth

1996

I.5 - Name of the workplace

2nd Department of Oncology, Faculty of Medicine, Comenius University and National Cancer Institute, Bratislava

I.6 - Address of the workplace

Klenova 1, 833 10 Bratislava

I.7 - Position

PhD student, full-time

I.8 - E-mail address

orszaghova9@uniba.sk

I.10 - Name of the study field in which a person works at the university

Oncology

I.11 - ORCID iD

0000-0002-6517-0380

II. - Higher education and further qualification growth

II.1 - First degree of higher education

II.2 - Second degree of higher education

II.a - Name of the university or institution

Faculty of Medicine, Comenius University in Bratislava

II.b - Year

2020

II.c - Study field and programme

General Medicine

II.3 - Third degree of higher education

II.4 - Associate professor

II.5 - Professor

II.6 - Doctor of Science (DrSc.)

III. - Current and previous employment

III.a - Occupation-position	III.b - Institution	III.c - Duration
Physician in training (Clinical Oncology)	2nd Department of Oncology, Faculty of Medicine, Comenius University and National Cancer Institute, Bratislava	2020 - present

IV. - Development of pedagogical, professional, language, digital and other skills

IV.a - Activity description, course name, other	IV.b - Name of the institution	IV.c - Year
Salzburg MSKCC Seminar in Oncology B: Uro-Oncology	Open Medical Institute	2022
Summer Data School - programming and statistical analysis of data	Data Science Academy	2023

V. - Overview of activities within the teaching career at the university

V.1 - Overview of the profile courses taught in the current academic year according to study programmes

V.2 - Overview of the responsibility for the delivery, development and quality assurance of the study programme or its part at the university in the current academic year

V.3 - Overview of the responsibility for the development and quality of the field of habilitation procedure and inaugural procedure in the current academic year

V.4 - Overview of supervised final theses

V.4.1 - Number of currently supervised theses

V.4.2 - Number of defended theses

V.5 - Overview of other courses taught in the current academic year according to study programmes

VI. - Overview of the research/artistic/other outputs

VI.1 - Overview of the research/artistic/other outputs and the corresponding citations

VI.1.1 - Number of the research/artistic/other outputs

VI.1.a - Overall

25 (Academic library FMED CU)

VI.1.b - Over the last six years

25

VI.1.2 - Number of the research/artistic/other outputs registered in the Web of Science or Scopus databases

VI.1.a - Overall

9 (Web of Science and SCOPUS)

VI.1.b - Over the last six years

9

VI.1.3 - Number of citations corresponding to the research/artistic/other outputs

VI.1.a - Overall

58 (Academic library FMED CU)

VI.1.b - Over the last six years

58

VI.1.4 - Number of citations registered in the Web of Science or Scopus databases

VI.1.a - Overall

61 (Web of Science) / 67 (SCOPUS)

VI.1.b - Over the last six years

61 (Web of Science) / 67 (SCOPUS)

VI.1.5 - Number of invited lectures at the international, national level

VI.1.a - Overall

4

VI.1.b - Over the last six years

4

VI.2 - The most significant research/artistic/other outputs

1

Országhová Z, Mego M, Chovanec M. Long-Term Cognitive Dysfunction in Cancer Survivors. Front Mol Biosci. 2021;8:770413. Published 2021 Dec 14. doi:10.3389/fmolb.2021.770413

2

Országhová Z, Kalavska K, Mego M, Chovanec M. Overcoming Chemotherapy Resistance in Germ Cell Tumors. Biomedicines. 2022;10(5):972. Published 2022 Apr 22. doi:10.3390/biomedicines10050972

3

Zuzana Orszaghova et al., Longitudinal assessment of cognitive functioning in testicular germ cell tumor survivors. JCO 42, 514-514(2024). DOI:10.1200/JCO.2024.42.4_suppl.514. Poster ASCO GU 2024, Abstract 514.

4

Orszaghova Z, Galikova D, Lesko P, et al. Chemotherapy-Induced Peripheral Neuropathy (CIPN) as a Predictor of Decreased Quality of Life in Testicular Germ Cell Tumor Survivors. Clin Genitourin Cancer. doi:10.1016/j.clgc.2024.102067

5

Országhová, Zuzana, Mária Rečková, Magdaléna Jablonická, and Beata Mladosievičová. 2019. “Kardiotoxicita vyvolaná inhibítormi imunitných kontrolných bodov používanými v imunoterapii nádorov: Cardiotoxicity induced by immune checkpoint inhibitors used in cancer immunotherapy”. Cardiology letters 28 (6): 210-217.

6

Országhová, Zuzana, Ľubica Harvanová, and Beata Mladosievičová. 2020. “Farmakologické a nefarmakologické možnosti zníženia rizika kardiotoxicity antracyklínov a trastuzumabu: Pharmacological and non-pharmacological possibilities of antracycline and trastuzumab cardiotoxicity risk reduction”. Onkológia 15 (4): 262-267.

VI.3 - The most significant research/artistic/other outputs over the last six years

1

Országhová Z, Mego M, Chovanec M. Long-Term Cognitive Dysfunction in Cancer Survivors. Front Mol Biosci. 2021;8:770413. Published 2021 Dec 14. doi:10.3389/fmolb.2021.770413

2

Országhová Z, Kalavska K, Mego M, Chovanec M. Overcoming Chemotherapy Resistance in Germ Cell Tumors. Biomedicines. 2022;10(5):972. Published 2022 Apr 22. doi:10.3390/biomedicines10050972

3

Zuzana Orszaghova et al., Longitudinal assessment of cognitive functioning in testicular germ cell tumor survivors. JCO 42, 514-514(2024). DOI:10.1200/JCO.2024.42.4_suppl.514. Poster ASCO GU 2024, Abstract 514.

4

Orszaghova Z, Galikova D, Lesko P, et al. Chemotherapy-Induced Peripheral Neuropathy (CIPN) as a Predictor of Decreased Quality of Life in Testicular Germ Cell Tumor Survivors. Clin Genitourin Cancer. doi:10.1016/j.clgc.2024.102067

5

Országhová, Zuzana, Mária Rečková, Magdaléna Jablonická, and Beata Mladosievičová. 2019. “Kardiotoxicita vyvolaná inhibítormi imunitných kontrolných bodov používanými v imunoterapii nádorov: Cardiotoxicity induced by immune checkpoint inhibitors used in cancer immunotherapy”. Cardiology letters 28 (6): 210-217.

6

Országhová, Zuzana, Ľubica Harvanová, and Beata Mladosievičová. 2020. “Farmakologické a nefarmakologické možnosti zníženia rizika kardiotoxicity antracyklínov a trastuzumabu: Pharmacological and non-pharmacological possibilities of antracycline and trastuzumab cardiotoxicity risk reduction”. Onkológia 15 (4): 262-267.

VI.4 - The most significant citations corresponding to the research/artistic/other outputs

1

Országhová Z, Mego M, Chovanec M. Long-Term Cognitive Dysfunction in Cancer Survivors. Front Mol Biosci. 2021;8:770413

Citation: Fleming, B. - Edison, P. - Kenny, L.: Cognitive impairment after cancer treatment: mechanisms, clinical characterization, and management. In: BMJ, vol. 380, 2023, art. no. e071726

2

Országhová Z, Kalavska K, Mego M, Chovanec M. Overcoming Chemotherapy Resistance in Germ Cell Tumors. Biomedicines. 2022;10(5):972.

Citation: Funke, K. - Einsfelder, U. - Hansen, A. - Arévalo, L. - Schneider, S. - Nettersheim, D. - Stein, V. - Schorle, H.: Genome-scale CRISPR screen reveals neddylation to contribute to cisplatin resistance of testicular germ celltumours. In: British Journal of Cancer, vol. 128, no. 12, 2023, s. 2270-2282

3

Országhová Z, Mego M, Chovanec M. Long-Term Cognitive Dysfunction in Cancer Survivors. Front Mol Biosci. 2021;8:770413

Citation: Zeng, H. - Hendriks, L.E.L. - Witlox, W.J.A. - Groen, H.J.M. - Dingemans, A.-M.C. - Praag, J. - Belderbos, J. - Houben, R. - van der Noort, V. - De Ruysscher, D.K.M.: Risk factors for cognitive impairment in radically treatedstage III NSCLC: Secondary findings of the NVALT-11 study. In: Radiotherapy and Oncology, vol. 183, 2023, art. no. 109627

4

Országhová Z, Mego M, Chovanec M. Long-Term Cognitive Dysfunction in Cancer Survivors. Front Mol Biosci. 2021;8:770413

Citation: Kuil, L.E. - Varkevisser, T.M.C.K. - Huisman, M.H. - Jansen, M. - Bunt, J. - Compter, A. - Ket, H. - Schagen, S.B. - Meeteren, A.Y.N.S.V. - Partanen, M. : Artificial and natural interventions for chemotherapy- and / or radiotherapy-induced cognitive impairment: A systematic review of animal studies. In: Neuroscience and Biobehavioral Reviews, vol. 157, 2024, art. no. 105514

5

Országhová Z, Kalavska K, Mego M, Chovanec M. Overcoming Chemotherapy Resistance in Germ Cell Tumors. Biomedicines. 2022;10(5):972.

Citation: Cuevas-Estrada, B. - Montalvo-Casimiro, M. - Herrera, L.A.: Breaking the Mold: Epigenetics and Genomics Approaches Addressing Novel Treatments and Chemoresponse in TGCT Patients. In: International Journal of Molecular Sciences,vol. 24, no. 9, 2023, art. no. 7873

VI.5 - Participation in conducting (leading) the most important research projects or art projects over the last six years

1

Principal investigator: UK/251/2021. Project title: SCFAs as a potential biomarker of cognitive impairment in long-term GCT survivors.

2

Principal investigator: UK/259/2023. Project title: Circulating miRNA-206, miRNA-132 and miRNA-134 as potential biomarkers of cognitive impairment in long-term GCT survivors.

3

Co-investigator: APVV-15-0086 - Identification of biomarkers associated with late chemotherapy toxicity in germ cell testicular tumors.

4

Co-investigator: APVV-19-0411 - Identification and validation of biomarkers and responsible molecular pathways of late toxicity of curative treatment in testicular germ cell tumors

5

Co-investigator: VEGA 1/0327/19. Identification of the role of microbiome and immune molecular mechanisms of cognitive dysfunctions due to late toxicity of testicular germ cell cancer treatment.

VII. - Overview of organizational experience related to higher education and research/artistic/other activities

VIII. - Overview of international mobilities and visits oriented on education and research/artistic/other activities in the given field of study

VIII.a - Name of the institution	VIII.b - Address of the institution	VIII.c - Duration (indicate the duration of stay)	VIII.d - Mobility scheme, employment contract, other (describe)
Indiana University Simon Comprehensive Cancer Center - Division of Hematology/Oncology	535 Barnhill Drive, 46202, Indianapolis, Indiana, USA	april - june 2023 (3 months)	clinical observership, tutelage: Assoc. Prof. Nabil Adra, MD

IX. - Other relevant facts

IX.a - If relevant, other activities related to higher education or research/artistic/other activities are mentioned

January 2024 - Merit Award recipient at ASCO Genitourinary Cancers Symposium 2024 (San Francisco) with the abstract „Longitudinal assessment of cognitive functioning in testicular germ cell tumor survivors.“

September 2023 - participation at the Falling Walls Lab Slovakia 2023 with the project „Breaking the wall of cognitive dysfunction“

March 2024 - participation at the Competition of Young Oncologists 2024 with the abstract "Chemotherapy-Induced Peripheral Neuropathy (CIPN) as a Predictor of Decreased Quality of Life in Testicular Germ Cell Tumor Survivors." Organizer: Cancer Research Foundation (SVK)

Date of last update

2024-04-29