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Name and surname:
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prof. RNDr. Jana Muchová, PhD.
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Document type:
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Research/art/teacher profile of a person
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The name of the university:
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Comenius University Bratislava
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The seat of the university:
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Šafárikovo námestie 6, 818 06 Bratislava
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| III.a - Occupation-position | III.b - Institution | III.c - Duration |
|---|---|---|
| University teacher - assistant | Comenius University, Medical Faculty | 1992 - 1996 |
| University teacher - assistant professor | Comenius University, Medical Faculty | 1996 - 2008 |
| University teacher - associate professor | Comenius University, Medical Faculty | 2008 - 2023 |
| University teacher - professor | Comenius University, Medical Faculty | 2023 until now |
| IV.a - Activity description, course name, other | IV.b - Name of the institution | IV.c - Year |
|---|---|---|
| Methods of molecular biology | Institute of Molecular Biology Slovak Academy of Sciences | 1992 |
| University lectures "Free radicals in biology and medicine" | Comenius University, Medical Faculty | 1996 |
| Biomedical statistics | Comenius University, Medical Faculty | 2006 |
| V.1.a - Name of the profile course | V.1.b - Study programme | V.1.c - Degree | V.1.d - Field of study |
|---|---|---|---|
| Lekárska chémia, Medical Chemistry (two subjects - education in slovak and english languages) | General medicine | I.+II. | General medicine |
| Lekárska chémia pre zubné lekárstvo / Medical Chemistry for Dentistry (two subjects - education in slovak and english languages) | Dentistry | I.+II. | Dentistry |
| Lekárska biochémia 1+2/Medical Biochemistry 1+2 (education in slovak and english languages) | General medicine | I.+II. | General medicine |
| Lekárska biochémia pre zubné lekárstvo 1+2 / Medical Biochemistry for dentistry 1+2 (education in slovak and english languages) | Dentistry | I.+II. | Dentistry |
| Klinická biochémia / Clinical Biochemistry | General Medicine | I.+II. | General Medicine |
| V.2.a - Name of the study programme | V.2.b - Degree | V.2.c - Field of study |
|---|---|---|
| Medical, Clinical and Pharmaceutical biochemistry | III. | General medicine |
| V.5.a - Name of the course | V.5.b - Study programme | V.5.c - Degree | V.5.d - Field of study |
|---|---|---|---|
| Biochemistry of physiological functions 1 | Biochemistry | II. | Chemistry |
| New Trends in Medical, Clinical and Pharmaceutical Biochemistry | Accredited Programs for General Medicine and Dentistry | III. | General Medicine |
| Basics of chemistry of living systems | Biomedical Physics / General Medicine, Faculty of Mathematics, Physics and Informatics, Comenius University | I. | Physics |
Muchová, Jana - Liptáková, Anna - Országhová, Zuzana - Garaiová, Iveta - Tisoň, Pavol - Čársky, Jozef - Ďuračková, Zdeňka: Antioxidant systems in polymorphonuclear leucocytes of Type 2 diabetes mellitus
In: Diabetic Medicine. - Vol. 16, No. 1 (1999), s. 74-78. - ISSN 0742-3071
Journal Indicator: IF (JCR) 1999=2,170; Q2
Reviews (86)
Muchová, Jana - Šustrová, Mária - Garaiová, Iveta - Liptáková, Anna - Blažíček, Pavol - Kvasnička, Peter - Pueschel, Siegfried - Ďuračková, Zdeňka: Influence of age on activities of antioxidant enzymes and lipid peroxidation products in erythrocytes and neutrophils of Down syndrome patients
In: Free Radical Biology & Medicine. - Vol. 31, No. 4 (2001), s. 499-508. - ISSN 0891-5849
Journal Indicator: IF (JCR) 2001=5.082; Q1
Reviews (102)
ESCODD - Gedik, C. M.- Collins, Andrew R. - Dubois, Jacques - Duez, Pierre - Kouegnigan, L. - Rees, Jean-Francois - Loft, Steffen - Moller, Peter - Jensen, A. - Poulsen, Henrik - Riss, B. - Weimann, A. - Cadet, Jean - Douki, Thierry - Ravanat, Jean-Luc - Sauvaigo, Sylvie - Faure, Henry - Morel, Isabelle - Morin, Bénédicte - Epe, Bernd - Eckert, I. - Hartwig, Andrea - Schwerdtle, Tanja - Dolara, Piero - Giovannelli, Lisa - Lodovici, Maura - Guglielmi, F. - Olinski, Ryszard - Bialkowski, Karol - Foksinski, Marek - Gackowski, Daniel - Ďuračková, Zdeňka - Muchová, Jana - Korytár, Peter - Sivoňová, Monika - Dušinská, Mária - Mišľanová, Csilla - Petrovská, Helena - Smolková, Božena - Viňa, José - Lloret, Ana - Saez, G.- Möller, Lennart - Hofer,Thomas - Eriksson, H. - Gremaud, Eric - Herbert, Karl - Wild, Chris - Kelly, Frank - Dunster, Chrisi - White, Ann - Wood, Sharon - Vaughan, Nicholas: Establishing the background level of base oxidation in human lymphocyte DNA: results of an interlaboratory validation study
In: FASEB Journal. - Vol. 19, No. 1 (2005), s. 82-84. - ISSN 0892-6638
Journal Indicator: IF (JCR) 2005=7.064; Q1
NOTE: Also published - FASEB Journal. - Vol. 18, No. 14 (2004), pp. [1-23]
Reviews (367)
Grimm, Tanja - Paduchová, Zuzana - Muchová, Jana - Sumegová, Katarína - Liptáková, Anna - Ďuračková, Zdeňka - Högger, Petra: Inhibition of NF-kappaB activation and MMP-9 secretion by plasma of human volunteers after ingestion of maritime pine bark extract (Pycnogenol)
In: Journal of Inflammation. - Vol. 3, No. 1 (2006), s. 1-6. - ISSN 1476-9255 (Electronic)
Ohlasy (136)
ADC14 Garaiová, Iveta - Muchová, Jana - Nagyová, Zuzana - Wang, Duolao - Li, J.V - Országhová, Zuzana - Daryn Michael R - Plummer, Sue F. - Ďuračková, Zdeňka: Probiotics and vitamin C for the prevention of respiratory tract infections in children attending preschool: a randomised controlled pilot study.
Iveta Garaiová and Jana Muchová: Equal contributors
In: The European Journal of Clinical Nutrition. - Vol. 69, No. 3 (2015), [7 p.]. - ISSN 0954-3007
Journal indicator: IF (JCR) 2015=2.935; Q2
Reviews (60)
Paduchová, Zuzana - Gajdošová, Lívia - Katrenčíková, Barbora - Horváthová, Martina - Országhová, Zuzana - Andrezálová, Lucia - Muchová, Jana: Synergistic Effects of Omega-3 Fatty Acids and Physical Activity on Oxidative Stress Markers and Antioxidant Mechanisms in Aged Rats.
In: Nutrients – Vol. 17, No. 1 (2025), pp. 1 - 14 (online); ISSN (online) 2072-6643; DOI 10.33549/physiolres.935245.
Journal Indicator: IF (JCR) 2024=5.0; Q1
Reviews (0)
Žitňanová, Ingrid - Oravec, Stanislav - Janubová, Mária - Koňariková, Katarína - Dvořáková, Monika - Laubertová, Lucia - Králová, Mária - Šimko, Martin - Muchová, Jana: Gender differences in LDL and HDL subfractions in atherogenic and nonatherogenic phenotypes
In: Clinical Biochemistry. - Roč. 79 (2020), s. 9-13. - ISSN (print) 0009-9120
Journal Indicator: IF (JCR) 2019=2,573; Q2
Reviews (14)
Michael Daryn. R. - Jack, A. A. - Masetti, G. - Davies, T. S. - Loxley, K.E. - Kerry-Smith, J. - Plummer, J. F. - Marchesi, J. R. - Mullish, B. H. - McDonald, J. A. K. - Hughes, T. R. - Wang, D. - Garaiová, Iveta - Paduchová, Zuzana - Muchová, Jana - Good, M. A. - Plummer, S. F.: A randomised controlled study shows supplementation of overweight and obese adults with lactobacilli and bifidobacteria reduces bodyweight and improves well-being
In: Scientific reports [elektronický dokument]. - Roč. 10, č. 6 (2020), s. [1-12], Art. no. 4183 [online]. - ISSN (online) 2045-2322
URL: https://www.nature.com/articles/s41598-020-60991-7.pdf
Journal Indicator: IF (JCR) 2020=4.380; Q1
Reviews (63)
Garaiová, Iveta - Paduchová, Zuzana - Nagyová, Zuzana - Wang, D. - Michael, D. R. - Plummer, S. F. - Marchesi, J. R. - Ďuračková, Zdeňka - Muchová, Jana: Probiotics with vitamin C for the prevention of upper respiratory tract symptoms in children aged 3-10 years: Randomised controlled trial
In: Beneficial Microbes. - Roč. 12, č. 5 (2021), s. 431-440. - ISSN (print) 1876-2883
URL: https://www.wageningenacademic.com/doi/epdf/10.3920/BM2020.0185
Journal Indicator: IF (JCR) 2020=4,205; Q2
Reviews (12)
Katrenčíková, Barbora - Vaváková, Magdaléna - Paduchová, Zuzana - Nagyová, Zuzana - Garaiová, Iveta - Muchová, Jana - Ďuračková, Zdeňka - Trebatická, Jana: Oxidative stress markers and antioxidant enzymes in children and adolescents with depressive disorder and impact of omega-3 fatty acids in randomised clinical trial
In: Antioxidants. - Roč. 10, č. 8 (2021), s. [1-16], art. no. 1256. - ISSN (online) 2076-3921
URL: https://www.mdpi.com/2076-3921/10/8/1256/pdf
Journal Indicator: IF (JCR) 2021=7.675; Q1
Reviews (33)
ADC01 Muchová a kol.; In: Diabetic Medicine - Vol. 16, No. 1 (1999) - ISSN 0742-3071; IF (JCR) 1999=2,170; Ohlasy (80)
[o1] 2003 Barringer, T.A. - Kirk, J.K. - Santaniello, A.C. - Foley, K.L. - Michielutte, R.: Ann. Intern. Med., vol. 138, no. 5, 2003, s. 365-371 - SCI ; SCOPUS
Muchová a kol.; In: Diabetic Medicine - Vol. 16, No. 1 (1999) - ISSN 0742-3071; IF (JCR) 1999=2,170; Ohlasy (80)
[o1] 2020 Tikhonova, I.V. - Grinevich, A.A. - Guseva, I.E. - Safronova, V.G.: Free Radical Biology and Medicine, vol. 159, 1 November 2020, s. 76-86
Muchová a kol; In: Free Radical Biology & Medicine. - Vol. 31, No. 4 (2001) - ISSN 0891-5849; IF (JCR) 2001=5,082; Ohlasy (94)
[o1] 2009 Cabelof, D.C. - Patel, H.V. - Chen, Q. - Van Remmen, H. - Matherly, L.H. - Ge, Y. - Taub, J.W.: Blood, vol. 114, no. 13, 2009, 2753-2763 - SCI; SCOPUS
ESCODD - Gedik a kol.; In: FASEB Journal. - Vol. 19, No. 1 (2005) - ISSN 0892-6638; Indikátor časopisu: IF (JCR) 2005=7,064; Ohlasy (192)
[o1] 2007 David, S.S. - O'Shea, V.L. - Kundu, S.: Nature, vol. 447, no. 7147, 2007, s. 941-950 - SCI
ESCODD - Gedik a kol.; In: FASEB Journal. - Vol. 19, No. 1 (2005) - ISSN 0892-6638; Indikátor časopisu: IF (JCR) 2005=7,064; Ohlasy (192)
[o1] 2019 Barciszewska, A.M. - Giel-Pietraszuk, M. - Perrigue, P.M. - Naskret-Barciszewska, M.: Cells, vol. 8, no. 9, 2019, art. no. 1065 - SCI
EU project from the Cross-border Cooperation Program SR-AT - Interreg, Nutriaging V-014: Nutrition and Healthy Aging (2016-2021);
principal investigator in SR
The aim of the project is to search for markers of "healthy aging" in experimental conditions at the cellular and animal level (Bratislava) and in a human study with seniors placed in facilities for the elderly (Vienna), which would assess the impact of lifestyle - dietary habits (consumption of omega-3 fatty acid, vitamins and other nutrients) and physical activity on the mental and physical condition of the elderly.
VEGA 1/0665/19: Influence of selected nutrients (proteins and vitamin D) and exercise on molecular mechanisms of sarcopenia (2019-2022);
principal investigator
The aim of the project is to study the effects of combined intervention (supplementation with selected nutrients (vitamin D and proteins) and exercise) on molecular mechanisms of sarcopenia in experimental models (animal experiment, cell cultures) through analysis of biochemical and inflammatory parameters, markers of oxidative stress and selected signaling molecules. in muscles that could play an important role in the pathophysiology of sarcopenia.
EU project from the Cross-border Cooperation Programme Interreg V -A SR-AT: Strengthening cross-border cooperation in the field of prevention of neurodegenerative diseases (NDD) with a focus on nutrition and exercise (BrainHealth) (2025-2027);
responsible researcher for SR
The main objective of the project is to comprehensively focus on the issue of brain aging and the increasing incidence of NDD in seniors through the development of innovative preventive and diagnostic approaches. The project aims to identify early functional, biochemical and molecular markers of the development of neurodegenerative processes, clarify the mechanisms leading to damage and repair of aging cells of the nervous system and verify the effectiveness of targeted nutritional intervention and physical activity as prevention tools.
The main objective also includes the development and implementation of a cross-border NDD prevention strategy and the preparation of specific action plans aimed at healthcare professionals, seniors and the future aging population. The project will thus contribute to strengthening early diagnosis, reducing the health and economic burden associated with NCDs, and supporting healthy aging of the population in the participating regions.
Contract project with Horphag Research (Europe) Ltd., Limassol, Cyprus (QR2019-01); Effect of French oak wood extract (Robuvit®) on muscle mass in seniors (RobuSar project) (2024-2026);
principal investigator
The aim of the project is to determine the effect of 6 weeks of Robuvit administration at a dose of 300 mg/day and the subsequent combination of Robuvit with strength-endurance training (12 weeks) on muscle mass, muscle strength, muscle performance, metabolic and mitochondrial parameters in seniors in a randomized double-blind, placebo-controlled study. The project aims to evaluate physical, biochemical and molecular markers of muscle growth, energy homeostasis and mitochondrial function to determine the extent to which Robuvit and its combination with exercise support skeletal muscle health and functional capacity in older people.
APVV-15-0308: Molecular-pharmacological approaches to innovative therapy of rheumatoid arthritis evaluated in experimental conditions in vivo and in vitro (2016-2020); principal investigator for CU MF
The aim of the project is to obtain information about the therapeutic potential of substances with immunomodulatory and antioxidant properties for RA therapy, especially combination therapy with MTX and to find out the mechanisms of action of substances regulating redox balance in biochemical and immunological processes accompanying arthritis at intra- and extracellular level.
| VII.a - Activity, position | VII.b - Name of the institution, board | VII.c - Duration |
|---|---|---|
| Guarantor of the subjects Medicinal Chemistry; Medical Biochemistry 1; Medical Biochemistry 2; Clinical Biochemistry for General Medicine medicine in Slovak and English | Comenius University, Medical Faculty | Medicinal Chemistry (2008 - present); other subjects from 2025 - present |
| Guarantor of the subjects Medicinal Chemistry for Dentistry; Medical Biochemistry 1 and 2 for Dentistry in Slovak and English | Comenius University, Medical Faculty | Medicinal Chemistry (2008 - present); other subjects from 2025 - present |
| Member of the company | Slovak Society of Biochemistry and Molecular Biology | 1991 - until now |
| Member of the company | Society for redox biology and medicine | 2010 - until now |
| Member of the company | Society for free radical research europe | 2010 - until now |
| VIII.a - Name of the institution | VIII.b - Address of the institution | VIII.c - Duration (indicate the duration of stay) | VIII.d - Mobility scheme, employment contract, other (describe) |
|---|---|---|---|
| Child Development Center, Rhode Island Hospital (Prof. Pueschel) | Providence, USA | May - July 1998 | US-Slovac Science and Technology programme 005/12-96 (1996 - 2002) |
| Department of Haemostatis and Haemostatic disorders Medical University (Prof. Watala) | Lodz, Poland | October 2004 | NATO collaborative linkage grant LST.CLG.980106 (2003-2005) |
| Department of Haemostatis and Haemostatic disorders Medical University (Prof. Watala) | Lodz, Poland | February-March 2005 | NATO collaborative linkage grant LST.CLG.980106 (2003-2005) |
Member of examination commissions for state examinations:
- Commission for bachelor degree studies at Faculty of Natural Sciences, Comenius University in
Bratislava
- Commission for Master's Degree Studies and Rigorous Proceedings at Faculty of Natural
Sciences, Comenius University in Bratislava
- Commission for doctoral studies in the field of Normal and Pathological Physiology, Faculty of
Medicine, Comenius University in Bratislava
- Commission for doctoral studies in the field of Medical, Clinical and Pharmaceutical Biochemistry
at Jessenius Faculty of Medicine, Comenius University in Martin
- Supervisor and expert authorized to take state examinations for doctoral studies (Chemistry
Section and Physics Program) at Faculty of Natural Sciences, Comenius University in Bratislava
- Committee Member and Opponent in the Field of Habilitation and Inauguration Proceedings in
Clinical Biochemistry (Faculty of Medicine, P.J. Šafárik University)