Name and surname:
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prof. RNDr. Jana Muchová, PhD.
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Document type:
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Research/art/teacher profile of a person
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The name of the university:
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Comenius University Bratislava
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The seat of the university:
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Šafárikovo námestie 6, 818 06 Bratislava
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III.a - Occupation-position | III.b - Institution | III.c - Duration |
---|---|---|
University teacher - assistant | Comenius University, Medical Faculty | 1992 - 1996 |
University teacher - assistant professor | Comenius University, Medical Faculty | 1996 - 2008 |
University teacher - associate professor | Comenius University, Medical Faculty | 2008 - 2023 |
University teacher - professor | Comenius University, Medical Faculty | 2023 until now |
IV.a - Activity description, course name, other | IV.b - Name of the institution | IV.c - Year |
---|---|---|
Methods of molecular biology | Institute of Molecular Biology Slovak Academy of Sciences | 1992 |
University lectures "Free radicals in biology and medicine" | Comenius University, Medical Faculty | 1996 |
Biomedical statistics | Comenius University, Medical Faculty | 2006 |
V.1.a - Name of the profile course | V.1.b - Study programme | V.1.c - Degree | V.1.d - Field of study |
---|---|---|---|
Lekárska chémia, Medical Chemistry (two subjects - education in slovak and english languages) | General medicine | I.+II. | General medicine |
Lekárska chémia pre zubné lekárstvo / Medical Chemistry for Dentistry (two subjects - education in slovak and english languages) | Dentistry | I.+II. | Dentistry |
Lekárska biochémia 1/Medical Biochemistry 1 (two subjects - education in slovak and english languages) | General medicine | I.+II. | General medicine |
Lekárska biochémia pre zubné lekárstvo 1 / Medical Biochemistry for dentistry 1 (two subjects - education in slovak and english languages) | Dentistry | I.+II. | Dentistry |
V.2.a - Name of the study programme | V.2.b - Degree | V.2.c - Field of study |
---|---|---|
Lekárska chémia / Medical Chemistry (two subjects - education in slovak and english languages) | I.+II. | General medicine |
Lekárska chémia pre zubné lekárstvo / Medical Chemistry for Dentistry (two subjects - education in slovak and english languages) | I.+II. | Dentistry |
Medical, clinical and pharmaceutical biochemistry | III. | General medicine |
V.5.a - Name of the course | V.5.b - Study programme | V.5.c - Degree | V.5.d - Field of study |
---|---|---|---|
Biochemistry of physiological functions 1 | Biochemistry | II. | Chemistry |
New trends in medical, clinical and pharmaceutical biochemistry | Accredited Programs for General Medicine and Dentistry | III. | General Medicine |
Basics of chemistry of living systems | Biomedical Physics / General Medicine, Faculty of Mathematics, Physics and Informatics, Comenius University | I. | Physics |
Muchová, Jana - Liptáková, Anna - Országhová, Zuzana - Garaiová, Iveta - Tisoň, Pavol - Čársky, Jozef - Ďuračková, Zdeňka: Antioxidant systems in polymorphonuclear leucocytes of Type 2 diabetes mellitus
In: Diabetic Medicine. - Vol. 16, No. 1 (1999), s. 74-78. - ISSN 0742-3071
Indikátor časopisu: IF (JCR) 1999=2,170; Q2
Ohlasy (84)
Muchová, Jana - Šustrová, Mária - Garaiová, Iveta - Liptáková, Anna - Blažíček, Pavol - Kvasnička, Peter - Pueschel, Siegfried - Ďuračková, Zdeňka: Influence of age on activities of antioxidant enzymes and lipid peroxidation products in erythrocytes and neutrophils of Down syndrome patients
In: Free Radical Biology & Medicine. - Vol. 31, No. 4 (2001), s. 499-508. - ISSN 0891-5849
Indikátor časopisu: IF (JCR) 2001=5,082; Q1
Ohlasy (98)
ESCODD - Gedik, C. M.- Collins, Andrew R. - Dubois, Jacques - Duez, Pierre - Kouegnigan, L. - Rees, Jean-Francois - Loft, Steffen - Moller, Peter - Jensen, A. - Poulsen, Henrik - Riss, B. - Weimann, A. - Cadet, Jean - Douki, Thierry - Ravanat, Jean-Luc - Sauvaigo, Sylvie - Faure, Henry - Morel, Isabelle - Morin, Bénédicte - Epe, Bernd - Eckert, I. - Hartwig, Andrea - Schwerdtle, Tanja - Dolara, Piero - Giovannelli, Lisa - Lodovici, Maura - Guglielmi, F. - Olinski, Ryszard - Bialkowski, Karol - Foksinski, Marek - Gackowski, Daniel - Ďuračková, Zdeňka - Muchová, Jana - Korytár, Peter - Sivoňová, Monika - Dušinská, Mária - Mišľanová, Csilla - Petrovská, Helena - Smolková, Božena - Viňa, José - Lloret, Ana - Saez, G.- Möller, Lennart - Hofer,Thomas - Eriksson, H. - Gremaud, Eric - Herbert, Karl - Wild, Chris - Kelly, Frank - Dunster, Chrisi - White, Ann - Wood, Sharon - Vaughan, Nicholas: Establishing the background level of base oxidation in human lymphocyte DNA: results of an interlaboratory validation study
In: FASEB Journal. - Vol. 19, No. 1 (2005), s. 82-84. - ISSN 0892-6638
Indikátor časopisu: IF (JCR) 2005=7,064; Q1
POZNÁMKA: Vyšlo aj - FASEB Journal. - Vol. 18, No. 14 (2004), s. [1-23]
Ohlasy (343)
Grimm, Tanja - Paduchová, Zuzana - Muchová, Jana - Sumegová, Katarína - Liptáková, Anna - Ďuračková, Zdeňka - Högger, Petra: Inhibition of NF-kappaB activation and MMP-9 secretion by plasma of human volunteers after ingestion of maritime pine bark extract (Pycnogenol)
In: Journal of Inflammation. - Vol. 3, No. 1 (2006), s. 1-6. - ISSN 1476-9255 (Electronic)
Ohlasy (133)
Garaiová, Iveta - Muchová, Jana - Nagyová, Zuzana - Mišľanová, Csilla - Oravec, Stanislav - Dukát, Andrej - Wang, Duolao - Plummer, Sue F. - Ďuračková, Zdeňka: Effect of a plant sterol, fish oil and B vitamin combination on cardiovascular risk factors in hypercholesterolemic children and adolescent: a pilot study
Iveta Garaiová and Jana Muchová: Equal contributors
In: Nutrition Journal. - Vol. 12, No. January (2013), Art. No. 7 [8 s.]. - ISSN 1475-2891
Indikátor časopisu: IF (JCR) 2013=2,635; Q2
Ohlasy (32)
Gajdošová, Lívia - Katrenčíková, Barbora - Borbélyová, Veronika - Muchová, Jana : The effect of omega-3 fatty acid supplementation and exercise on locomotor activity, exploratory activity, and anxiety-like behavior in adult and aged rats.
In: Physiological research – Roč. 73, č. 3 (2024), s. 461-480; ISSN 0862-8408. – ISSN (online) 1802-9973; DOI 10.33549/physiolres.935245.
Indikátor časopisu: IF (JCR) 2023=1,94; Q3
Ohlasy (0)
Žitňanová, Ingrid - Oravec, Stanislav - Janubová, Mária - Koňariková, Katarína - Dvořáková, Monika - Laubertová, Lucia - Králová, Mária - Šimko, Martin - Muchová, Jana: Gender differences in LDL and HDL subfractions in atherogenic and nonatherogenic phenotypes
In: Clinical Biochemistry. - Roč. 79 (2020), s. 9-13. - ISSN (print) 0009-9120
Indikátor časopisu: IF (JCR) 2019=2,573; Q2
Ohlasy (14)
Michael Daryn. R. - Jack, A. A. - Masetti, G. - Davies, T. S. - Loxley, K.E. - Kerry-Smith, J. - Plummer, J. F. - Marchesi, J. R. - Mullish, B. H. - McDonald, J. A. K. - Hughes, T. R. - Wang, D. - Garaiová, Iveta - Paduchová, Zuzana - Muchová, Jana - Good, M. A. - Plummer, S. F.: A randomised controlled study shows supplementation of overweight and obese adults with lactobacilli and bifidobacteria reduces bodyweight and improves well-being
In: Scientific reports [elektronický dokument]. - Roč. 10, č. 6 (2020), s. [1-12], Art. no. 4183 [online]. - ISSN (online) 2045-2322
URL: https://www.nature.com/articles/s41598-020-60991-7.pdf
Indikátor časopisu: IF (JCR) 2020=4.380; Q1
Ohlasy (63)
Garaiová, Iveta - Paduchová, Zuzana - Nagyová, Zuzana - Wang, D. - Michael, D. R. - Plummer, S. F. - Marchesi, J. R. - Ďuračková, Zdeňka - Muchová, Jana: Probiotics with vitamin C for the prevention of upper respiratory tract symptoms in children aged 3-10 years: Randomised controlled trial
In: Beneficial Microbes. - Roč. 12, č. 5 (2021), s. 431-440. - ISSN (print) 1876-2883
URL: https://www.wageningenacademic.com/doi/epdf/10.3920/BM2020.0185
Indikátor časopisu: IF (JCR) 2020=4,205; Q2
Ohlasy (12)
Katrenčíková, Barbora - Vaváková, Magdaléna - Paduchová, Zuzana - Nagyová, Zuzana - Garaiová, Iveta - Muchová, Jana - Ďuračková, Zdeňka - Trebatická, Jana: Oxidative stress markers and antioxidant enzymes in children and adolescents with depressive disorder and impact of omega-3 fatty acids in randomised clinical trial
In: Antioxidants. - Roč. 10, č. 8 (2021), s. [1-16], art. no. 1256. - ISSN (online) 2076-3921
URL: https://www.mdpi.com/2076-3921/10/8/1256/pdf
Indikátor časopisu: IF (JCR) 2021=7.675; Q1
Ohlasy (33)
ADC01 Muchová a kol.; In: Diabetic Medicine - Vol. 16, No. 1 (1999) - ISSN 0742-3071; IF (JCR) 1999=2,170; Ohlasy (80)
[o1] 2003 Barringer, T.A. - Kirk, J.K. - Santaniello, A.C. - Foley, K.L. - Michielutte, R.: Ann. Intern. Med., vol. 138, no. 5, 2003, s. 365-371 - SCI ; SCOPUS
Muchová a kol.; In: Diabetic Medicine - Vol. 16, No. 1 (1999) - ISSN 0742-3071; IF (JCR) 1999=2,170; Ohlasy (80)
[o1] 2020 Tikhonova, I.V. - Grinevich, A.A. - Guseva, I.E. - Safronova, V.G.: Free Radical Biology and Medicine, vol. 159, 1 November 2020, s. 76-86
Muchová a kol; In: Free Radical Biology & Medicine. - Vol. 31, No. 4 (2001) - ISSN 0891-5849; IF (JCR) 2001=5,082; Ohlasy (94)
[o1] 2009 Cabelof, D.C. - Patel, H.V. - Chen, Q. - Van Remmen, H. - Matherly, L.H. - Ge, Y. - Taub, J.W.: Blood, vol. 114, no. 13, 2009, 2753-2763 - SCI; SCOPUS
ESCODD - Gedik a kol.; In: FASEB Journal. - Vol. 19, No. 1 (2005) - ISSN 0892-6638; Indikátor časopisu: IF (JCR) 2005=7,064; Ohlasy (192)
[o1] 2007 David, S.S. - O'Shea, V.L. - Kundu, S.: Nature, vol. 447, no. 7147, 2007, s. 941-950 - SCI
ESCODD - Gedik a kol.; In: FASEB Journal. - Vol. 19, No. 1 (2005) - ISSN 0892-6638; Indikátor časopisu: IF (JCR) 2005=7,064; Ohlasy (192)
[o1] 2019 Barciszewska, A.M. - Giel-Pietraszuk, M. - Perrigue, P.M. - Naskret-Barciszewska, M.: Cells, vol. 8, no. 9, 2019, art. no. 1065 - SCI
EU project from the Cross-border Cooperation Program SR-AT - Interreg, Nutriaging V-014: Nutrition and Healthy Aging (2016-2021);
principal investigator in SR
The aim of the project is to search for markers of "healthy aging" in experimental conditions at the cellular and animal level (Bratislava) and in a human study with seniors placed in facilities for the elderly (Vienna), which would assess the impact of lifestyle - dietary habits (consumption of omega-3 fatty acid, vitamins and other nutrients) and physical activity on the mental and physical condition of the elderly.
APVV-15-0308: Molecular-pharmacological approaches to innovative therapy of rheumatoid arthritis evaluated in experimental conditions in vivo and in vitro (2016-2020); principal investigator for CU MF
The aim of the project is to obtain information about the therapeutic potential of substances with immunomodulatory and antioxidant properties for RA therapy, especially combination therapy with MTX and to find out the mechanisms of action of substances regulating redox balance in biochemical and immunological processes accompanying arthritis at intra- and extracellular level.
VEGA 1/0665/19: Influence of selected nutrients (proteins and vitamin D) and exercise on molecular mechanisms of sarcopenia (2019-2022);
principal investigator
The aim of the project is to study the effects of combined intervention (supplementation with selected nutrients (vitamin D and proteins) and exercise) on molecular mechanisms of sarcopenia in experimental models (animal experiment, cell cultures) through analysis of biochemical and inflammatory parameters, markers of oxidative stress and selected signaling molecules. in muscles that could play an important role in the pathophysiology of sarcopenia.
VEGA 1/0183/24: Suicidality in children and adolescents, neurobiological parameters, and their mutual association (2024-2027);
deputy principal investigator
The project focuses on determining the relationship between the incidence of suicidal ideation and attempts in children aged 15-19 years and psychiatric diagnosis, on investigating neurobiological correlates with a focus on direct and indirect inflammatory markers, anti-inflammatory cytokines, lipid profile, markers of oxidative and nitrosylation stress, the rate of the limiting enzyme of GSH synthesis (glutamylcysteinyl ligase) and the Nrf2/Keap1/ARE signaling pathway compared to the control group of healthy children.
Contract project with Horphag Research (Europe) Ltd., Limassol, Cyprus (QR2023-03); RobuFaL Study: Effects of Robuvit on the healing process of non-alcoholic fatty liver disease (2024-2025);
principal investigator
The aim of the project is to determine, in a randomized double-blind and placebo-controlled study, the effect of 12-week administration of Robuvit at a dose of 300 mg/day on the symptoms of the disease, the progression of tissue fibrosis, the mechanisms involved in the liver regeneration process and the quality of life of patients with non-alcoholic fatty liver disease (NAFLD) or metabolically linked non-alcoholic fatty liver disease (MAFLD).
VII.a - Activity, position | VII.b - Name of the institution, board | VII.c - Duration |
---|---|---|
Guarantor of the subject Lekárska chémia pre Zubné lekárstvo (education in slovak language) | Comenius University, Medical Faculty | 2008 - until now |
Guarantor of the subject Medical Chemistry for Dentistry (education in english language) | Comenius University, Medical Faculty | 2008 - until now |
Member of the company | Slovak Society of Biochemistry and Molecular Biology | 1991 - until now |
Member of the company | Society for redox biology and medicine | 2010 - until now |
Member of the company | Society for free radical research europe | 2010 - until now |
VIII.a - Name of the institution | VIII.b - Address of the institution | VIII.c - Duration (indicate the duration of stay) | VIII.d - Mobility scheme, employment contract, other (describe) |
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Child Development Center, Rhode Island Hospital (Prof. Pueschel) | Providence, USA | May - July 1998 | US-Slovac Science and Technology programme 005/12-96 (1996 - 2002) |
Department of Haemostatis and Haemostatic disorders Medical University (Prof. Watala) | Lodz, Poland | October 2004 | NATO collaborative linkage grant LST.CLG.980106 (2003-2005) |
Department of Haemostatis and Haemostatic disorders Medical University (Prof. Watala) | Lodz, Poland | February-March 2005 | NATO collaborative linkage grant LST.CLG.980106 (2003-2005) |
Member of examination commissions for state examinations:
- Commission for bachelor degree studies at Faculty of Natural Sciences, Comenius University in
Bratislava
- Commission for Master's Degree Studies and Rigorous Proceedings at Faculty of Natural
Sciences, Comenius University in Bratislava
- Commission for doctoral studies in the field of Normal and Pathological Physiology, Faculty of
Medicine, Comenius University in Bratislava
- Commission for doctoral studies in the field of Medical, Clinical and Pharmaceutical Biochemistry
at Jessenius Faculty of Medicine, Comenius University in Martin
- Supervisor and expert authorized to take state examinations for doctoral studies (Chemistry
Section and Physics Program) at Faculty of Natural Sciences, Comenius University in Bratislava
- Committee Member and Opponent in the Field of Habilitation and Inauguration Proceedings in
Clinical Biochemistry (Faculty of Medicine, P.J. Šafárik University)