I. - Basic information

I.1 - Surname

Melikishvili

I.2 - Name

Sopio

I.3 - Degrees

Mgr, PhD

I.4 - Year of birth

1983

I.5 - Name of the workplace

Institute of medical physics and biophysics, MF CU

I.6 - Address of the workplace

Sasinkova 2, III. floor, 813 72 Bratislava

I.7 - Position

Assistant professor

I.8 - E-mail address

sopio.melikishvili.fmed.uniba.sk

I.9 - Hyperlink to the entry of a person in the Register of university staff

https://www.portalvs.sk/regzam/detail/26278?mode=full&do=filterForm-submit&surname=Melikishvili&sort=surname&employment_state=yes&filter=Vyh%C4%BEada%C5%A5

I.10 - Name of the study field in which a person works at the university

General Medicine

I.11 - ORCID iD

56483287800

II. - Higher education and further qualification growth

II.1 - First degree of higher education

II.a - Name of the university or institution

Ivane Javakhishvili Tbilisi State University

II.b - Year

2008

II.c - Study field and programme

Physics

II.2 - Second degree of higher education

II.a - Name of the university or institution

Comenius University

II.b - Year

2012

II.c - Study field and programme

Biophysics and chemical physics

II.3 - Third degree of higher education

II.a - Name of the university or institution

Comenius University

II.b - Year

2016

II.c - Study field and programme

Biophysics

II.4 - Associate professor

II.5 - Professor

II.6 - Doctor of Science (DrSc.)

III. - Current and previous employment

III.a - Occupation-position	III.b - Institution	III.c - Duration
Assistant professor	Institute of medical physics and biophysics, MF CU	2024- up to now
Scientific researcher	Department of nuclear physics and biophysics, Faculty of Mathematics, Physics and Informatics CU	2016-2023

IV. - Development of pedagogical, professional, language, digital and other skills

V. - Overview of activities within the teaching career at the university

V.1 - Overview of the profile courses taught in the current academic year according to study programmes

V.1.a - Name of the profile course	V.1.b - Study programme	V.1.c - Degree	V.1.d - Field of study
Medical biophysics	General medicine, Dentistry	I.+II.	General medicine

V.2 - Overview of the responsibility for the delivery, development and quality assurance of the study programme or its part at the university in the current academic year

V.3 - Overview of the responsibility for the development and quality of the field of habilitation procedure and inaugural procedure in the current academic year

V.4 - Overview of supervised final theses

V.4.1 - Number of currently supervised theses

V.4.2 - Number of defended theses

V.5 - Overview of other courses taught in the current academic year according to study programmes

VI. - Overview of the research/artistic/other outputs

VI.1 - Overview of the research/artistic/other outputs and the corresponding citations

VI.1.1 - Number of the research/artistic/other outputs

VI.1.a - Overall

VI.1.b - Over the last six years

VI.1.2 - Number of the research/artistic/other outputs registered in the Web of Science or Scopus databases

VI.1.a - Overall

VI.1.b - Over the last six years

VI.1.3 - Number of citations corresponding to the research/artistic/other outputs

VI.1.a - Overall

VI.1.b - Over the last six years

VI.1.4 - Number of citations registered in the Web of Science or Scopus databases

VI.1.a - Overall

VI.1.b - Over the last six years

VI.1.5 - Number of invited lectures at the international, national level

VI.2 - The most significant research/artistic/other outputs

Vasil G. Bregadze, Eteri S. Gelagutashvili, Ketevan J. Tsakadze, Sophie Z. Melikishvili, Metal- Induced Point defects in DNA: Model and Mechanisms, Chem. Biodivers. 2008, 5, 1980-1989

Maxim Ionov, Karol Ciepluch, Zuzana Garaiova, Sophie Melikishvili, Sylwia Michlewska, Łucja Balcerzak, Sława Glińska, Katarzyna Miłowska, Rafael Gomez-Ramirez, Francisco Javier de la Mata, Dzmitry Shcharbin, Iveta Waczulikova, Maria Bryszewska, Tibor Hianik, Dendrimers Complexed with HIV-1 Peptides interact with liposomes and lipid monolayers, Biochim. Biophys. Acta -Biomembranes 2015, 1848, 907-915

Sophie Melikishvili, Alexandra Poturnayova, Maksim Ionov, Maria Bryszewska, Tomáš Vary, Julius Cirak, María Ángeles Muñoz-Fernández, Rafael Gomez-Ramirez, Francisco Javier de la Mata, Tibor Hianik, The effect of polyethylene glycol-modified lipids on the interaction of HIV-1derived peptide-dendrimer complexes with lipid membranes, Biochim. Biophys. Acta -Biomembranes 2016, 1858, 3005-3016

Habib Baghirov, Sopio Melikishvili, Yrr Mørch, Einar Sulheim, Andreas K.O. Åslund, Tibor Hianik, Catharina de Lange Davies, The effect of poly(ethylene glycol) coating and monomer typeon poly(alkyl cyanoacrylate) nanoparticle interactions with lipid monolayers and cells, Colloids Surf. B: Biointerfaces. 2017, 150, 373-383

VI.3 - The most significant research/artistic/other outputs over the last six years

Sopio Melikishvili., Mark Dizon, Tibor Hianik, Application of high-resolution ultrasonic spectroscopy for real-time monitoring of trypsin activity in β-casein solution, Food Chem. 2021, 337.

Ivan Piovarci, Sopio Melikishvili, Marek Tatarko, Tibor Hianik, Michael Thompson, Detection of Sub-Nanomolar Concentration of Trypsin by Thickness-Shear Mode Acoustic Biosensor and Spectrophotometry. Biosensors 2021, 11, 117.

Zuzana Garaiova, Sopio Melikishvili, Sylwia Michlewska ,Maksim Ionov, Elzbieta Pedziwiatr-Werbicka, Iveta Waczulikova, Tibor Hianik, Rafael Gomez-Ramirez, Francisco Javier de la Mata, Maria Bryszewska, Dendronized Gold Nanoparticles as Carriers forgp160 (HIV-1) Peptides: Biophysical Insight into Complex Formation. Langmuir. 2021, 37.

Katarzyna Milowska, Andrea Rodacka, Sopio Melikishvili, Adam Buczkowski, Bartlomiej Pałecz, Iveta Waczulikova, Tibor Hianik, Jean pierre Majoral, Maksim Ionov, Maria Bryszewska, Dendrimeric HIV-peptide delivery nanosystem affects lipid membranes structure. Sci Rep. 2021, 11, 16810.

Sopio Melikishvili, Ivan Piovarci, Tibor Hianik, Advances in Colorimetric Assay Based on AuNPs Modified by Proteins and Nucleic Acid Aptamers. Chemosensors 2021, 9, 281.

VI.4 - The most significant citations corresponding to the research/artistic/other outputs

Buckin, V.: High-resolution ultrasonic spectroscopy. In: Journal of Sensors and Sensor Systems, Vol. 7, No. 1, 2018, p. 207-217 -- SCI ; SCOPUS

~ Qiao, L. - Chen, M. - Li, S. - Hu, J. - Gong, C. - Zhang, Z. - Cao, X.: A peptide-based subunit candidate vaccine against SARS-CoV-2 delivered by biodegradable mesoporous silica nanoparticles induced high humoral and cellularimmunity in mice. In: Biomaterials Science, Vol. 9, No. 21, 2021, p. 7287-7296.

Jampílek, J. - Kráľová, K.: Nanotechnology: New frontiers in anti-HIV therapy. In: Nanotechnological Applications in Virology. London : Academic Press, 2022, p. 129-171.

Deng, G. - Zha, H. - Luo, H. - Zhou, Y.: Aptamer-conjugated gold nanoparticles and their diagnostic and therapeutic roles in cancer. In: Frontiers in Bioengineering and Biotechnology, No. 11, 2023, art. no. 1118546.

VI.5 - Participation in conducting (leading) the most important research projects or art projects over the last six years

H2020-MSCA-RISE-2020, project number 10100729, design of biosensors for the detection of bacteria in the frame of project SAFEMILK.

VEGA 1/0419/20 The study of interaction of nanomotors modified with aptamers and biomembranes

VII. - Overview of organizational experience related to higher education and research/artistic/other activities

VIII. - Overview of international mobilities and visits oriented on education and research/artistic/other activities in the given field of study

IX. - Other relevant facts

Date of last update

2025-02-25

Name and surname:	Mgr. Sopio Melikishvili, PhD.
Document type:	Research/art/teacher profile of a person
The name of the university:	Comenius University Bratislava
The seat of the university:	Šafárikovo námestie 6, 818 06 Bratislava