I. - Basic information

I.1 - Surname

Kyselovič

I.2 - Name

Ján

I.3 - Degrees

Prof. PharmDr. CSc. FESC FIACS

I.4 - Year of birth

1963

I.5 - Name of the workplace

Clinical Research Unit. 5th Department of Internal Medicine, Faculty of Medicine and University Hospital, Comenius University Bratislava

I.6 - Address of the workplace

Ružinovská 6, 826 06 Bratislava

I.7 - Position

Researcher

I.8 - E-mail address

Kyselovic@uniba.sk

I.9 - Hyperlink to the entry of a person in the Register of university staff

https://www.portalvs.sk/regzam/detail/3738

I.10 - Name of the study field in which a person works at the university

Pharmacology

I.11 - ORCID iD

0000-0001-9208-5352

II. - Higher education and further qualification growth

II.1 - First degree of higher education

II.a - Name of the university or institution

Faculty of Pharmacy, Comenius University Bratislava

II.b - Year

1987

II.c - Study field and programme

Clinical pharmacy

II.2 - Second degree of higher education

II.c - Study field and programme

Pharmacology

II.3 - Third degree of higher education

II.a - Name of the university or institution

Faculty of Medicine, Comenius University Bratislava

II.b - Year

1993

II.c - Study field and programme

Pharmacology

II.4 - Associate professor

II.a - Name of the university or institution

Faculty of Pharmacy, Comenius University Bratislava

II.b - Year

2003

II.c - Study field and programme

Pharmacology

II.5 - Professor

II.a - Name of the university or institution

Faculty of Pharmacy, Comenius University Bratislava

II.b - Year

2009

II.c - Study field and programme

Pharmacology

II.6 - Doctor of Science (DrSc.)

III. - Current and previous employment

III.a - Occupation-position	III.b - Institution	III.c - Duration
Head of CRU	Clinical Research Unit. 5th Department of Internal Medicine, Faculty of Medicine and University Hospital, Comenius University Bratislava	2017
Clinical Research Unit. 5th Department of Internal Medicine, Faculty of Medicine and University Hospital, Comenius University Bratislava	Faculty of Medicine, Comenius University Bratislava	2013-2015
Professor	Faculty of Pharmacy, Comenius University Bratislava	2009-2017
employee	Comenius Unveristy Bratislava	1987-2009

IV. - Development of pedagogical, professional, language, digital and other skills

V. - Overview of activities within the teaching career at the university

V.1 - Overview of the profile courses taught in the current academic year according to study programmes

V.2 - Overview of the responsibility for the delivery, development and quality assurance of the study programme or its part at the university in the current academic year

V.3 - Overview of the responsibility for the development and quality of the field of habilitation procedure and inaugural procedure in the current academic year

V.4 - Overview of supervised final theses

V.4.1 - Number of currently supervised theses

V.4.a - Bachelor's (first degree)

V.4.b - Diploma (second degree)

101

V.4.c - Dissertation (third degree)

V.4.2 - Number of defended theses

V.4.a - Bachelor's (first degree)

V.4.b - Diploma (second degree)

101

V.4.c - Dissertation (third degree)

V.5 - Overview of other courses taught in the current academic year according to study programmes

V.5.a - Name of the course	V.5.b - Study programme	V.5.c - Degree	V.5.d - Field of study
Physiological principles of pharmacology	Animal Physiology	II	Animal Physiology and ethology

VI. - Overview of the research/artistic/other outputs

VI.1 - Overview of the research/artistic/other outputs and the corresponding citations

VI.1.1 - Number of the research/artistic/other outputs

VI.1.a - Overall

945

VI.1.b - Over the last six years

187

VI.1.2 - Number of the research/artistic/other outputs registered in the Web of Science or Scopus databases

VI.1.a - Overall

WoS/SCOPUS 170/165

VI.1.b - Over the last six years

WoS/SCOPUS 53/69

VI.1.3 - Number of citations corresponding to the research/artistic/other outputs

VI.1.a - Overall

WoS/SCOPUS 1858/2051

VI.1.b - Over the last six years

WoS/SCOPUS 1216/1320

VI.1.4 - Number of citations registered in the Web of Science or Scopus databases

VI.1.a - Overall

WoS/SCOPUS 1858/2051

VI.1.b - Over the last six years

WoS/SCOPUS 1216/1320

VI.1.5 - Number of invited lectures at the international, national level

VI.1.a - Overall

VI.1.b - Over the last six years

VI.2 - The most significant research/artistic/other outputs

2006-2010 6. Frame Programm EU- STREP 034256 Deep-Vein Thrombosis – Impedimetric Microanalysis Systém

Jan Kyselovic, Peter Krenek, Maurice Wibo, Théophile Godfraind. Effects of amlodipine and lacidipine on cardiac remodelling and renin production in salt-loaded stroke-prone hypertensive rats Br J Pharmacol. 2001 IF (JCR) 2001=3,502, SCI cit.55

A Samakova, A Gazova, N Sabova, S Valaskova, M Jurikova, J KyselovicThe pi3k/Akt Pathway Is Associated With Angiogenesis, Oxidative Stress and Survival of Mesenchymal Stem Cells in Pathophysiologic Condition in Ischemia. 2019 PHYSIOLOGICAL RESEARCH, 68 , pp.S131-S138, IF (JCR) 2016=2,226, SCI cit.136

Feng Gao, Masaharu Kataoka, Ning Liu, Tian Liang, Zhan-Peng Huang, Fei Gu, Jian Ding, Jianming Liu, Feng Zhang, Qing Ma, Yingchao Wang, Mingming Zhang, Xiaoyun Hu, Jan Kyselovic, Xinyang Hu, William T Pu, Jian’an Wang, Jinghai Chen, Da-Zhi Wang: Therapeutic role of miR-19a/19b in cardiac regeneration and protection from myocardial infarction, Nature commun 2019, 10 (1), 1802, IF (JCR) 2019=12,121, SCI cit.251

Krenek P, Kmecova J, Kucerova D, Bajuszova Z, Musil P, Gazova A, Ochodnicky P, Klimas J, Kyselovic J. Isoproterenol-induced heart failure in the rat is associated with nitric oxide-dependent functional alterations of cardiac function. Eur J Heart Fail. 2009 Feb;11(2):140-6. IF (JCR) 2009=3,9 Q1, SCI cit.85

VI.3 - The most significant research/artistic/other outputs over the last six years

Haipeng Guo, Yao Wei Lu, Zhiqiang Lin, Zhan-Peng Huang, Jianming Liu, Yi Wang, Hee Young Seok, Xiaoyun Hu, Qing Ma, Kathryn Li, Jan Kyselovic, Qingchuan Wang, Jenny L-C Lin, Jim J-C Lin, Douglas B Cowan, Francisco Naya, Yuguo Chen, William T Pu, Da-Zhi WangIntercalated disc protein Xinβ is required for Hippo-YAP signaling in the heart. Nature commun, 2020,11, 4666, IF (JCR) 2020=14,919Q1 SCI cit.16

Adamičková A, Chomaničová N, Gažová A, Maďarič J, Červenák Z, Valášková S, Adamička M, Kyselovic J. Effect of Atorvastatin on Angiogenesis-Related Genes VEGF-A, HGF and IGF-1 and the Modulation of PI3K/AKT/mTOR Transcripts in Bone-Marrow-Derived Mesenchymal Stem Cells. Curr Issues Mol Biol. 2023 Mar 10;45(3):2326-2337 IF (JCR) 2023=2,919Q1 SCI cit.9

Kyselovic J, Adamičková A, Gažová A, Valášková S, Chomaničová N, Červenák Z, Madaric J. Atorvastatin Treatment Significantly Increased the Concentration of Bone Marrow-Derived Mononuclear Cells and Transcutaneous Oxygen Pressure and Lowered the Pain Scale after Bone Marrow Cells Treatment in Patients with "No-Option" Critical Limb Ischaemia. Biomedicines. 2024 Apr 22;12(4):922 IF (JCR) 2023=4,9 Q1 SCI cit.9

Samakova A, Gazova A, Sabova N, Valaskova S, Jurikova M, Kyselovic J. The PI3k/Akt pathway is associated with angiogenesis, oxidative stress and survival of mesenchymal stem cells in pathophysiologic condition in ischemia. Physiol Res. 2019 Nov 30;68(Suppl 2):S131-S138. doi: 10.33549/physiolres.934345. PMID: 31842576.

VI.4 - The most significant citations corresponding to the research/artistic/other outputs

2024 Awarded with title:: Fellow of European Cardiology Society

2025 Awarded with title 2025 Fellow of International Academy of Cardiovascular Society

Celkový počet ohlasov WoS/SCOPUS 1858/2051

Collaboration: 33.3% International collaboration during the last 10 years 458 co-authors with researchers in other countries/regions

24.7% (20 documents/ last 10 years) Documents in top 25% journals by CiteScore percentile

VI.5 - Participation in conducting (leading) the most important research projects or art projects over the last six years

BIOFORD_Systemic public research infrastructure – biobank for cancer and rare diseases EU, state budget: 313011AGF5 18 mil. EUR 2020 - 2023 Key researcher of partner of the project

USCCCORD: Increasing the capacities and competences of the Comenius University in research, development and innovation EU, state budget: 313021BUZ3 5,8 mil. EUR 2022 - 2023 Key researcher of partner of the project

PROMEGA_Research and development in medical sciences - the way to personalized treatment of serious neurological, cardiovascular and tumor diseases EU, state budget: 313011T431 13,1 mil. EUR 2016 - 2019 Principal investigator of partner of the project

BIOMIN_Strategic industrial research and development of human medicines based on calcium biopreparations aimed at the prevention and treatment of osteological civilization diseases EU, state budget: 313012Q751 2,0 mil. EUR 2019 - 2022 Principal investigator of partner of the project

Regenerative potential of pharmacological intervetion to the GATA4, HAND2, MEF2C and TBX5 signal pathways in cell based therapy of cardiovascular diseases. State budget: APVV-14-0416 250 000€ 2015-2019 Principal investigator

VII. - Overview of organizational experience related to higher education and research/artistic/other activities

VII.a - Activity, position	VII.b - Name of the institution, board	VII.c - Duration
Vice-Chairman of the Doctoral Study Committee 7.1.30 Pharmacology	Faculty of Pharmacy, Comenius University Bratislava	2005-2011
Member of the doctoral study committee No. 51-22-99 Toxicology	Jessenius Faculty of Medicine in Martin	2005- doteraz
Member of Research Board, Charles University, Praha, Czech Republic	Charles University, Praha, Czech Republic	2010-
Chairman of the doctoral study committee 7.1.30 Pharmacology	Faculty of Pharmacy, Comenius University Bratislava	2010-2017
EU expert for Inovative Medicíne EMA, London	European Medicines Agency	2012- 2018

VIII. - Overview of international mobilities and visits oriented on education and research/artistic/other activities in the given field of study

VIII.a - Name of the institution	VIII.b - Address of the institution	VIII.c - Duration (indicate the duration of stay)	VIII.d - Mobility scheme, employment contract, other (describe)
Faculty of Medicine, Department Pharmacology, University of Ottawa, Canada	Ottawa, Canada	1992	4 months travel grant MRC of Canada
Faculty of Medicine, Department Pharmacology, University of Ottawa, Canada	Ottawa, Canada	1993-1994	MDAC post-gradual stay
Department Pharmacology and toxicology, Catholic University Louvain	Brusselles, Belgium	1996-2021	visiting scientist
Sainte Justine Hospital Motreal	Montreal, Canada	2004	visiting scientist

IX. - Other relevant facts

IX.a - If relevant, other activities related to higher education or research/artistic/other activities are mentioned

985: Slovak Academy of Sciences Award: "Best Student Scientific Paper"

1987: Rector of Comenius University Award for excellent academic results Cum Laudum

1989-1992: Member of the Academic Senate of the Faculty of Medicine, Comenius University

1995-1996: Member of the Academic Senate of the Faculty of Pharmacy, Comenius University – Senate Secretary

2003-2009: Member of the Academic Senate of Comenius University 2006-2009: Member of the Council of Higher Education Institutions 2013: Slovak Pharmaceutical Society Award

2013: Faculty of Pharmacy, Comenius University, Hradec Králové Award

2015-2017: Member of the Men's Health EU Advisory Board

2023: Zuffa Medal, Slovak Pharmaceutical Medal

2023: Bronze Medal, Faculty of Medicine, Comenius University Bratislava

2023: Silver Medal, Slovak Medical Society

Date of last update

2025-03-05

Name and surname:	prof. PharmDr. Ján Kyselovič, CSc.
Document type:	Research/art/teacher profile of a person
The name of the university:	Comenius University Bratislava
The seat of the university:	Šafárikovo námestie 6, 818 06 Bratislava