Name and surname:
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Mgr. Alexandra Gaál Kovalčíková, PhD.
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Document type:
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Research/art/teacher profile of a person
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The name of the university:
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Comenius University Bratislava
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The seat of the university:
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Šafárikovo námestie 6, 818 06 Bratislava
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III.a - Occupation-position | III.b - Institution | III.c - Duration |
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Researcher | Department of Pediatrics, National Institute of Children’s diseases and Faculty of Medicine, Comenius University in Bratislava | 1.10.2018 - present |
IV.a - Activity description, course name, other | IV.b - Name of the institution | IV.c - Year |
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English language examination within PhD. study | Faculty of Medicine, Comenius University | 2015 |
Scientific degree IIA | Faculty of Medicine, Comenius University | 2022 |
V.1.a - Name of the profile course | V.1.b - Study programme | V.1.c - Degree | V.1.d - Field of study |
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Basics of theoretical and experimental medicine | Medical Biology | Bachelor | Biology |
Gyuraszova M, Kovalcikova A, Gardlik R. Association between oxidative status and the composition of intestinal microbiota along the gastrointestinal tract. Med Hypotheses. 2017;103:81-85. doi: 10.1016/j.mehy.2017.04.011.
Kovalčíková A, Gyurászová M, Vavrincová-Yaghi D, Vavrinec P, Tóthová Ľ, Boor P, Šebeková K, Celec P. Oxidative stress in the brain caused by acute kidney injury. Metab Brain Dis. 2018;33(3):961-967. doi: 10.1007/s11011-018-0204-8.
Gaál Kovalčíková A, Pančíková A, Konečná B, Klamárová T, Novák B, Kovaľová E, Podracká Ľ, Celec P, Tóthová Ľ. Urea and creatinine levels in saliva of patients with and without periodontitis. Eur J Oral Sci. 2019;127(5):417-424. doi: 10.1111/eos.12642.
Lauková L, Bertolo EMJ, Zelinková M, Borbélyová V, Čonka J, Gaál Kovalčíková A, Domonkos E, Vlková B, Celec P. Early Dynamics of Plasma Dna in a Mouse Model of Sepsis. Shock. 2019;52(2):257-263. doi: 10.1097/SHK.0000000000001215.
Kovalčíková AG, Pavlov K, Lipták R, Hladová M, Renczés E, Boor P, Podracká Ľ, Šebeková K, Hodosy J, Tóthová Ľ, Celec P. Dynamics of salivary markers of kidney functions in acute and chronic kidney diseases. Sci Rep. 2020;10(1):21260. doi: 10.1038/s41598-020-78209-1.
Konečná, B.; Gaál Kovalčíková, A.; Pančíková, A.; Novák, B.; Kovaľová, E.; Celec, P.; Tóthová, Ľ. Salivary Extracellular DNA and DNase Activity in Periodontitis. Appl Sci. 2020, 10: 7490. https://doi.org/10.3390/app10217490.
Renczés E, Marônek M, Gaál Kovalčíková A, Vavrincová-Yaghi D, Tóthová L, Hodosy J. Behavioral Changes During Development of Chronic Kidney Disease in Rats. Front Med. 2020;6:311. doi: 10.3389/fmed.2019.00311.
Kovalčíková AG, Tichá Ľ, Šebeková K, Celec P, Čagalová A, Sogutlu F, Podracká Ľ. Oxidative status in plasma, urine and saliva of girls with anorexia nervosa and healthy controls: a cross-sectional study. J Eat Disord. 2021;9(1):54. doi: 10.1186/s40337-021-00408-6.
Kovalčíková A, Janšáková K, Gyurászová M, Podracká Ľ, Šebeková K, Celec P, Tóthová Ľ. Salivary creatinine and urea are higher in an experimental model of acute but not chronic renal disease. PLoS One. 2018;13(7):e0200391. doi: 10.1371/journal.pone.0200391.
Marianna Gyurászová, Alexandra Kovalčíková, Janka Bábíčková, Július Hodosy, Ľubomíra Tóthová,
Cell-free nucleic acids in urine as potential biomarkers of kidney disease. J Appl Biomed. 2018,16(3):157-164. doi:10.1016/j.jab.2018.01.007.
Eshraghi RS, Deth RC, Mittal R, Aranke M, Kay SS, Moshiree B, Eshraghi AA. Early Disruption of the Microbiome Leading to Decreased Antioxidant Capacity and Epigenetic Changes: Implications for the Rise in Autism. Front Cell Neurosci. 2018;12:256. doi: 10.3389/fncel.2018.00256.
Kellum JA, Romagnani P, Ashuntantang G, Ronco C, Zarbock A, Anders HJ. Acute kidney injury. Nat Rev Dis Primers. 2021;7(1):52. doi: 10.1038/s41572-021-00284-z.
Methatham T, Tomida S, Kimura N, Imai Y, Aizawa K. Inhibition of the canonical Wnt signaling pathway by a β-catenin/CBP inhibitor prevents heart failure by ameliorating cardiac hypertrophy and fibrosis. Sci Rep. 2021;11(1):14886. doi: 10.1038/s41598-021-94169-6.
Jiang L, Gong Y, Rao J, Yang Q, Gao N, Li G, Ma Y. 1-O-Hexyl-2,3,5-Trimethylhydroquinone Ameliorates the Development of Preeclampsia through Suppression of Oxidative Stress and Endothelial Cell Apoptosis. Oxid Med Cell Longev. 2021;2021:8839394. doi: 10.1155/2021/8839394.
Tsao CW, Hsu YJ, Chang TC, Wu ST, Cha TL, Liu CY. A High Phosphorus Diet Impairs Testicular Function and Spermatogenesis in Male Mice with Chronic Kidney Disease. Nutrients. 2020;12(9):2624. doi: 10.3390/nu12092624.
VEGA 1/0234/18 Molecular mechanism of antimicrobial effect of steroids on uropathogenic bacteria.
APVV-18-0287 Non-invasive and yet unused markers of renal function: problems, causes and opportunities
VEGA 1/0204/17 The role extracellular DNA in the pathogenesis and treatment of inflammatory bowel diseases.
VEGA 1/0613/17 Early diagnostics of osteoporosis in children and adolescents with anorexia nervosa.
Grant of Ministry of Health of the Slovak Republic 2018/36-LFUK-10 Innovative methods in diagnosis of skeletal dysplasia and premature osteoporosis in pediatric population.
VIII.a - Name of the institution | VIII.b - Address of the institution | VIII.c - Duration (indicate the duration of stay) | VIII.d - Mobility scheme, employment contract, other (describe) |
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Institute of Clinical Pathology, Medical University, Vienna | Institute of Clinical Pathology, Währinger Gürtel 18-20, Vienna | 1.10.2015 - 31.3.2016 | Research stay |
Important Conferences
Student scientific conferences, 93rd and 94th Physiological Days, 8th RECOOP Annual Project Review Meeting, 10th, 11th and 12th Conference of Pediatric Nephrology, Falling Walls Lab, ES-PCR: European Society of Pediatric Clinical Research 2018 and 2019, XIII. Congress of the Slovak Society of Clinical Biochemistry, DNA day 2019, 58th And 59th Pediatric days, 4th and 5th Days of Clinical Research in Kramare (the winner), 8th Congress of the International Pediatric Nephrology Association in Venice, 53rd Annual Scientific Meeting of the European Society for Peadiatric Nephrology in Amsterdam
Grants as principal Investigator during PhD. study:
Comenius University Grants UK/56/2016 Saliva as a model of diagnostic fluid in an acute kidney injury.
Comenius University Grants UK/355/2017 The effect of adenine-enriched food on tubulointerstitial fibrosis in mice.