Name and surname:
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doc. RNDr. Michal Šimera, PhD.
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Document type:
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Research/art/teacher profile of a person
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The name of the university:
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Comenius University Bratislava
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The seat of the university:
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Šafárikovo námestie 6, 818 06 Bratislava
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III.a - Occupation-position | III.b - Institution | III.c - Duration |
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Assistant professor position | Department of Medical Biophysics, Jessenius faculty of Medicine in Martin, Comenius University in Bratislava | from September 1st, 2012 to November 1st, 2019 |
Department of Medical Biophysics, Jessenius faculty of Medicine in Martin, Comenius University in Bratislava | from November 1st, 2019 to October 31st, 2024 |
IV.a - Activity description, course name, other | IV.b - Name of the institution | IV.c - Year |
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Course of Medical Tuition | Jessenius faculty of Medicine in Martin, Comenius University in Bratislava | 2020 |
Protection of animals used for scientific or educational purposes "retraining" | Veterinary Trianing Institute, Cesta pod Hradovou 13/A, 041 77 Košice | 2023 |
V.1.a - Name of the profile course | V.1.b - Study programme | V.1.c - Degree | V.1.d - Field of study |
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Medical Biophysics | General Medicine | II. | General Medicine |
Medical Biophysics 1 | Medical Biophysics | III. | General Medicine |
Medical Biophysics | Dentistry, Dental Medicine | II. | Dentistry, Dental Medicine |
Biophysics and Radiology | Nursing | I. | Nursing |
Biophysics and Radiology | Public Health | I. | Public Health |
Biophysics and Radiology | Midwifery | I. | Midwifery |
Medical Biophysics 2 | Medical Biophysics | III. | General medicine |
Medical Biophysics | Biomedical Engineering | I. | Biomedical Engineering |
V.3.a - Name of the field of habilitation procedure and inaugural procedure | V.3.b - Study field to which it is assigned |
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Medical biophysics | General medicine |
V.5.a - Name of the course | V.5.b - Study programme | V.5.c - Degree | V.5.d - Field of study |
---|---|---|---|
ŠVOČ (1) | General medicine | II. | General medicine |
ŠVOČ (2) | General medicine | II. | General medicine |
ŠVOČ (3) | General medicine | II. | General medicine |
ŠVOČ (4) | General medicine | II. | General medicine |
ŠVOČ (5) | General medicine | II. | General medicine |
Simera M, Berikova D, Hovengen OJ, Laheye M, Veternik M, Martvon L, Kotmanova Z, Cibulkova L, Poliacek I.Role of the pontine respiratory group in the suppression of cough by codeine in cats. Respir Physiol Neurobiol. 2024 Dec;330:104326. doi: 10.1016/j.resp.2024.104326. Epub 2024 Aug 28. PMID: 39209015
Poliacek I, Veternik M, Martvon L, Kotmanova Z, Babalova L, Cibulkova L, Berikova D, Plevkova J, Pitts T, Adzimova S, Simera M. Airway mechanics alters generation of cough motor pattern. Respir Physiol Neurobiol. 2024 Oct;328:104315. doi: 10.1016/j.resp.2024.104315. Epub 2024 Aug 14. PMID: 39128767
Simera M, Veternik M, Martvon L, Kotmanova Z, Cibulkova L, Poliacek I. Differential inhibition of cough by GABAA and GABAB receptor antagonists in the nucleus of the solitary tract in cats. Respir Physiol Neurobiol. 2023 Sep;315:104115. doi: 10.1016/j.resp.2023.104115. Epub 2023 Jul 17. PMID: 37460080
Simera M, Veternik M, Martvon L, Kotmanova Z, Mostafavi S, Bosko O, Kralikova O, Poliacek I. Distinct modulation of tracheal and laryngopharyngeal cough via superior laryngeal nerve in cat. Respir Physiol Neurobiol. 2021 Nov;293:103716. doi: 10.1016/j.resp.2021.103716. Epub 2021 Jun 10. PMID: 34119702
Martvon L, Kotmanova Z, Dobrolubov B, Babalova L, Simera M, Veternik M, Pitts T, Jakus J, Poliacek I. Modulation of Cough Reflex by Gaba-Ergic Inhibition in Medullary Raphé of the Cat. Physiol Res. 2020 Mar 27;69(Suppl 1):S151-S161. doi: 10.33549/physiolres.934401. PMID: 32228021 Free PMC article.
Simera M, Berikova D, Hovengen OJ, Laheye M, Veternik M, Martvon L, Kotmanova Z, Cibulkova L, Poliacek I.Role of the pontine respiratory group in the suppression of cough by codeine in cats. Respir Physiol Neurobiol. 2024 Dec;330:104326. doi: 10.1016/j.resp.2024.104326. Epub 2024 Aug 28. PMID: 39209015
Poliacek I, Veternik M, Martvon L, Kotmanova Z, Babalova L, Cibulkova L, Berikova D, Plevkova J, Pitts T, Adzimova S, Simera M. Airway mechanics alters generation of cough motor pattern. Respir Physiol Neurobiol. 2024 Oct;328:104315. doi: 10.1016/j.resp.2024.104315. Epub 2024 Aug 14. PMID: 39128767
Simera M, Veternik M, Martvon L, Kotmanova Z, Cibulkova L, Poliacek I. Differential inhibition of cough by GABAA and GABAB receptor antagonists in the nucleus of the solitary tract in cats. Respir Physiol Neurobiol. 2023 Sep;315:104115. doi: 10.1016/j.resp.2023.104115. Epub 2023 Jul 17. PMID: 37460080
Simera M, Veternik M, Martvon L, Kotmanova Z, Mostafavi S, Bosko O, Kralikova O, Poliacek I. Distinct modulation of tracheal and laryngopharyngeal cough via superior laryngeal nerve in cat. Respir Physiol Neurobiol. 2021 Nov;293:103716.
Martvon L, Kotmanova Z, Dobrolubov B, Babalova L, Simera M, Veternik M, Pitts T, Jakus J, Poliacek I. Modulation of Cough Reflex by Gaba-Ergic Inhibition in Medullary Raphé of the Cat. Physiol Res. 2020 Mar 27;69(Suppl 1):S151-S161. doi: 10.33549/physiolres.934401. PMID: 32228021 Free PMC article.
ADC08 Poliaček, Ivan (aut) [UKOLJ140] (55%) - Pitts, Teresa E. (aut) (15%) - Rose, Melanie J. (aut) (5%) - Davenport, Paul W. (aut) (1%) - Šimera, Michal (aut) [UKOLJ140] (3%) - Veterník, Marcel (aut) [UKOLJ140] (3%) - Kotmanová, Zuzana (aut) (3%)- Bolser, Donald C. (aut) [KAUT] (15%): Microinjection of kynurenic acid in the rostral nucleus of the tractus solitarius disrupts spatiotemporal aspects of mechanically induced tracheobronchial cough
In: Journal of Neurophysiology. - Roč. 117, č. 6 (2017), s. 2179-2187. - ISSN 0022-3077
Ohlasy (6):
[o1] 2017 ~ Mutolo, D.: Respiratory Physiology and Neurobiology, roč. 243, 2017, s. 60-76 -- SCI ; SCOPUS
[o1] 2018 ~ Cinelli, E. - Iovino, L. - Bongianni, F. - Pantaleo, T. - Mutolo, D.: Respiratory Physiology and Neurobiology, roč. 257, 2018, s. 93-99 -- SCI ; SCOPUS
[o1] 2019 ~ Bautista, T. G. - Leech, J. - Mazzone, S. B. - Farrell, M. J.: Journal of Neurophysiology, roč. 121, č. 4, 2019, s. 1171-1182 -- SCI ; SCOPUS
[o3] 2020 ~ Mutolo, D. - Iovino, L. - Cinelli, E. - Bongianni, F. - Pantaleo, T.: Brainstem Structures Involved in the Generation of Reflex Cough. In: Zanasi, A. - Gontana, G. A. - Mutolo, D.: Cough: Pathophysiology, Diagnosis and Treatment. Cham : Springer, 2020, S. 45-71
[o1] 2020 ~ Singh, N. - Driessen, A. K. - McGovern, A. E. - Moe, A. A. K. - Farrell, M. J. - Mazzone, S. B.: Journal of Thoraic Disease, roč. 12, č. 9, 2020, s. 5179-5193 -- SCI ; SCOPUS
[n2] 2023 zz ~ Plevková J.: Relevance of animal models in cough research. Martin : Vydavateľstvo Osveta, 2023, S. 1-134
Šimera, Michal (aut) [UKOLJ140] (50%) - Poliaček, Ivan (aut) [KAUT] [UKOLJ140] (30%) - Veterník, Marcel (aut) [UKOLJ140] (5%) - Babálová, Lucia (aut) (5%) - Kotmanová, Zuzana (aut) (5%) - Jakuš, Ján (aut) [UKOLJ140] (5%): Changes in vagal afferent drive alter tracheobronchial coughing in anesthetized cats
In: Respiratory Physiology & Neurobiology. - Roč. 230 (2016), s. 36-43. - ISSN (print) 1569-9048
Ohlasy (3):
[o1] 2017 ~ Mutolo, D.: Respiratory Physiology and Neurobiology, roč. 243, 2017, s. 60-76 -- SCI ; SCOPUS
[o3] 2020 ~ Mutolo, D. - Iovino, L. - Cinelli, E. - Bongianni, F. - Pantaleo, T.: Physiology of the Cough Reflex: Sensory and Mechanical Features. In: Zanasi, A. - Gontana, G. A. - Mutolo, D.: Cough: Pathophysiology, Diagnosis and Treatment. Cham : Springer, 2020, S. 3-20
[n1] 2022 zz ~ Shen, T. Y. - Pertzborn, M. C. - Rose, M. J. - Musselwhite, M. N. - Davenport, P. W. - Bolser, D. C.: Respiratory Physiology and Neurobiology, č. 296, 2022, čl. č. 103805 -- SCOPUS
Poliaček, Ivan (aut) [UKOLJ140] (58%) - Šimera, Michal (aut) [KAUT] [UKOLJ140] (15%) - Veterník, Marcel (aut) [UKOLJ140] (6%) - Kotmanová, Zuzana (aut) (6%) - Bolser, Donald C. (aut) (6%) - Macháč, Peter (aut) (3%) - Jakuš, Ján (aut) [UKOLJ140] (6%): Role of the dorsomedial medulla in suppression of cough by codeine in cats
Lit.: 68 zázn.
In: Respiratory Physiology & Neurobiology. - Roč. 246 (2017), s. 59-66. - ISSN (print) 1569-9048
Ohlasy (5):
[o1] 2018 ~ Cinelli, E. - Iovino, L. - Bongianni, F. - Pantaleo, T. - Mutolo, D.: Respiratory Physiology and Neurobiology, roč. 257, č. S1, 2018, s. 93-99 -- SCI ; SCOPUS
[o1] 2019 ~ Ye, L. X. - Huang, B. G. - Lin, Y. J. - Chen, F. - Li, J. - Huang, P. - Shen, X. W.: Latin American Journal of Pharmacy, roč. 38, č. 3, 2019, s. 477-480 -- SCI ; SCOPUS
[o1] 2020 ~ Yeung, D. T. - Bough, K. J. - Harper, J. R. - Platoff, G. E.: JOurnal of Medical Toxicology, roč. 16, č. 1, 2020, s. 87-105 -- SCI ; SCOPUS
[o3] 2020 ~ Mutolo, D. - Iovino, L. - Cinelli, E. - Bongianni, F. - Pantaleo, T.: Brainstem Structures Involved in the Generation of Reflex Cough. In: Zanasi, A. - Gontana, G. A. - Mutolo, D.: Cough: Pathophysiology, Diagnosis and Treatment. Cham : Springer, 2020, S. 45-71
[o1] 2020 ~ Gretler, S. R. - Finno, C. J. - McKemie, D. S. - Kass, P. H. - Knych, H. K.: Veterinary Anaesthesia and Analgesia, roč. 47, č. 5, 2020, s. 697-704 -- SCI ; SCOPUS
ADC10 Kotmanová, Zuzana (aut) (45%) - Šimera, Michal (aut) [KAUT] [UKOLJ140] (10%) - Veterník, Marcel (aut) [UKOLJ140] (7%) - Martvoň, Lukáš (aut) [UKOLJ140] (8%) - Míšek, Jakub (aut) [UKOLJ140] (5%) - Jakuš, Ján (aut) [UKOLJ140] (2%) - Shen,Tabitha Y. (aut) (2%) - Musselwhite, Nicholas M. (aut) (2%) - Pitts, Teresa (aut) (2%) - Bolser, Donald C. (aut) (2%) - Poliaček, Ivan (aut) [UKOLJ140] (15%): GABA-ergic neurotransmission in the nucleus of the solitary tract modulates cough in the cat. In: Respiratory Physiology & Neurobiology. - č. 261 (2019), s. 9-14. - ISSN (print) 1569-9048
Ohlasy (4):
[o1] 2018 ~ Plevkova, J. - Hanacek, J. - Tatar, M.: Respiratory Physiology and Neurobiology, roč. 257, č. S1, 2018, s. 1-4 -- SCI ; SCOPUS
[o1] 2020 ~ Song, S. Y. - Li, Y. - Zhai, X. M. - Li, Y. H. - Bao, C. Y. - Shan, C. J. - Hong, J. - Cao, J. L. - Zhang, L. C.: Frontiers in Neural Circuits, roč. 14, 2020, čl. č. 11 -- SCI ; SCOPUS
[o3] 2020 ~ Mutolo, D. - Iovino, L. - Cinelli, E. - Bongianni, F. - Pantaleo, T.: Brainstem Structures Involved in the Generation of Reflex Cough. In: Zanasi, A. - Gontana, G. A. - Mutolo, D.: Cough: Pathophysiology, Diagnosis and Treatment. Cham : Springer, 2020, S. 45-71
[o1] 2021 ~ Straus, C. - Teulier, M. - Morel, S. - Wattiez, N. - Hajage, D. - Giboin, C. - Charbit, B. - Dasque, E. - Bodineau, L. - Chenuel, B. - Straus, N. - Attali, V. - Similowski, T.: British Journal of Clinical Pharmacology, roč. 87, č.4, 2021, s. 1814-1823 -- SCI ; SCOPUS
Šimera, Michal (aut) [UKOLJ140] (60%) - Poliaček, Ivan (aut) [UKOLJ140] (30%) - Jakuš, Ján (aut) [UKOLJ140] (10%): Central antitussive effect of codeine in the anesthetized rabbit
In: European Journal of Medical Research. - Roč. 15, č. 4, suppl. 2 (2010), s. 184-188. - ISSN 0949-2321
[International Conference "Advances in Pneumology". Waršava, 27.-29.5.2010]
Indikátor časopisu:
IF (JCR) 2010=1,092
Ohlasy (18):
[o1] 2011 ~ Mazzone, S. B. - McGovern, A. E. - Cole, L. J. - Farrell, M. J.: Central nervous system ... In: Current Opinion in Pharmacology, roč. 11, č. 3, 2011, s. 265-271 -- SCI ; SCOPUS
[o4] 2012 ~ Nosáľová, Gabriela - Nosáľ, Slavomír: Ako liečiť kašeľ?. In: Praktické lekárnictvo, roč. 2, č. 1, 2012, s. 19-21
[o1] 2013 ~ Nosáľová, G. - Flešková, D. - Jureček, Ľ. - Sadloňová, V. - Ray, B.: Herbal polysaccharides and cough reflex. In: Respiratory Physiology & Neurobiology, roč. 187, č. 1, 2013, s. 47-51 -- SCI ; SCOPUS
[o1] 2013 ~ Nosáľová, G. - Jureček, L. - Hromadková, Z. - Košťálová, Z. - Sadloňová, V.: Antioxidant activity of herbal ... In: Advances in Experimental Medicine and Biology, roč. 788, 2013, s. 51-57 -- SCI ; SCOPUS
[o1] 2014 ~ Nosáľová, G. - Majee, S. K. - Ghosh, K. - Raja, W. - Chatterjee, U. R. - Jureček, Ľ. - Ray, B.: International Journal of Biological Macromolecules, 69, máj 2014, s. 151-157 -- SCI ; SCOPUS
[o3] 2014 ~ Kabera, J. N. - Semana, E. - Mussa, A. R. - He, X.: Journal of Pharmacy and Pharmacology, 2, 2014, s. 377-392
[o1] 2015 ~ Mazzone, S. B. - McGovern, A. E. - Farrell, M. J.: Current Opinion in Pharmacology, roč. 22, 2015, s. 1-8 -- SCI ; SCOPUS
[o1] 2015 ~ Iwata, T. - Ito, I. - Niimi, A. - Ikegami, K. - Marumo, S. - Tanabe, N. - Nakaji, H. - Kanemitsu, Y. - Matsumoto, H. - Kamei, J. - Setou, M. - Mishima, M.: PLoS ONE, roč. 10, č. 11, 2015, čl. č. e0141823 -- SCI ; SCOPUS
[o1] 2016 ~ Mutolo, D. - Cinelli, E. - Iovino, L. - Pantaleo, T. - Bongianni, F.: Pulmonary Pharmacology and Therapeutics, roč. 38, jún, 2016, s. 1-9 -- SCI ; SCOPUS
[o1] 2016 ~ Zhong, S. - Liu, X.-D. - Nie, Y.C. - Gan, Z.-Y. - Yang, L.-Q. - Huang, C.-Q. - Lai, K.-F. - Zhong, N.-S.: Journal of Ethnopharmacology, roč. 194, december, 2016, s. 378-385 -- SCI ; SCOPUS
[o1] 2018 ~ Velu, G. - Palanichamy, V. - Rajan, A. P.: Phytochemical and pharmacological importance of plant secondary metabolites in modern medicine. In: Bioorganic Phase in Natural Food: An Overview. Cham : Springer, 2018, S. 135-156 --SCOPUS
[o1] 2018 ~ Sengupta, G. - Gaurav, A. - Tiwari, S.: Synthesis of Medicinal Agents from Plants. Amsterdam : Elsevier, 2018, S. 47-74 -- SCI
[o1] 2021 ~ Olsen, W. L. - Rose, M. - Golder, F. J. - Wang, C. - Hammond, J. C. - Bolser, D. C.: Frontiers in Physiology, roč. 12, 2021, čl. č. 640682 -- SCI ; SCOPUS
[n1] 2021 zz ~ Muhammad, A. - Akhtar, A. - Aslam, S. - Khan, R. S. - Ahmed, Z. - Khalid, N.: Functional Foods in Health and disease, roč. 11, č. 10, 2021, s. 522-547 -- SCI ; SCOPUS
[n1] 2021 zz ~ Al-Maliki, A. D. M. - AI- Maliki, A. A. H. - Hameed, M. A. A.: Journal of Physics: Conference Series, roč. 2063, č. 1, 2021, čl. č. 012026 -- SCOPUS
[n1] 2022 zz ~ Twaij, B. M. - Hasan, M. N.: International Journal of Plant Biology, roč. 13, č. 1, 2022, s. 4-14 -- SCOPUS
[n1] 2022 zz ~ El-Ramady, H. - Hajdú, P. - Törős, G. - Badgar, K. - Llana, X. - Kiss, A. - Abdalla, N. - Omara, A. E. D. - Elsakhawy, T. - Elbasiouny, H. - Elbehiry, F. - Amer, M. - El-Mahrouk, M. E. - Prokisch, J.: Sustainability, roč. 14, č.14, 2022, čl. č. 8329 -- SCI ; SCOPUS
[n1] 2022 zz ~ Chung, K. F. - McGarvey, L. - Song, W. J. - Chang, A. B. - Lai, K. - Canning, B. J. - Birring, S. S. - Smith, J. A. - Mazzone, S. B.: Nature Reviews Disease Primers, roč. 8, č. 1, 2022, čl. č. 45 -- SCI ; SCOPUS
Project VEGA 1/0275/19 (Principal investigator): Coordination of respiratory tract defensive mechanisms and cardiorespiratory functions in experimental animals; Results of the project will significantly improve our knowledge of regulatory mechanisms of cardiovascular and respiratory system, respiratory tract defensive reflexes with their activation through peripheral inputs as well as with modified functions of central brainstem structures. Stimulations and changes in afferent activities and reflex responses, including their modifications, will allow us to analyze their interactions when altered, e.g. under pathological conditions. Various modes of stimulations and reduction of the afferent signal are expected to be used. The function of the central structures will be modulated by the microinjections of neuroactive substances applied mainly into the dorsolateral pons Varoli – an essential area of cardiorespiratory control and regulation of airway reflexes, mainly the cough reflex. The model of spontaneously breathing anesthetized animals (cats and rabbits etc.) will be used.
Project VEGA 1/0253/15 (Principal investigator): Interactions of neuronal structures controlling respiratory and cardiomotor functions in anesthetized animals; The aim of our project is to clarify the effect of peripheral stimulation and central brainstem structures on cardiomotor functions and generation or modulation of respiratory reflexes with focus on their interactions and integration. Stimulation of afferent pathways and a generation of reflex responses or their modulation (e.g. by a cold blockade) will contribute to the clarification of central control mechanisms and coordination of cardiorespiratory motor acts. Selected brainstem structures will be challenged by microinjections of neuromediators, neuromodulators, or central antitussive agents, and the importance of these structures for generation, modulation, and coordination of respiratory reflex responses and their coordination with cardiovascular functions will be uncovered. Electrophysiological experiments will be performed on the model of anesthetized, spontaneously breathing
animals (e,g, cat, rabbit, guinea pig, etc.).
PProject KEGA č. 072UK-4/2017 (Principal imvestigator): The preparation of textbook and modernization of educational approach in tuition process of Medical Biophysics – use of e-learning; The proposed project is intended for the theoretical and practical tuition of physical and biophysical basics in general medicine program and dentistry program, and for the implementation of e-learning elements in the tuition process. The publication of a new and modern textbook to improve the quality of the tuition process is required. A new textbook will cover the knowledge necessary for successful understanding of the compulsory curriculum for biophysics in the 1st year of medicine study. A part of the modernization of the tuition process will be the renovation of current practical tasks with orientation to direct application of biophysics in medicine. The modern tuition processes such as problem-solving in groups, the ideas of evidence-based medicine, case studies, ability to define the theoretical knowledge learned, will be applied.
VII.a - Activity, position | VII.b - Name of the institution, board | VII.c - Duration |
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Student Scientific Activity, The Chair of the Organizing Committee | Jessenius faculty of Medicine in Martin, Comenius University in Bratislava | 2016 - until now |
Member of Slovak Biophysical Society | Institute of Biophysics, Faculty of Science, Pavol Jozef Šafárik University in Košice. | 2009 - until now |
VIII.a - Name of the institution | VIII.b - Address of the institution | VIII.c - Duration (indicate the duration of stay) | VIII.d - Mobility scheme, employment contract, other (describe) |
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Department of Physiological Sciences | College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA | 13.02. - 01.05.2013 | Memorandum of understanding |
Department of Physiological Sciences | College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA | 01.04. - 01.06.2015 | Memorandum of understanding; |