I. - Basic information

I.1 - Surname

Mikolka

I.2 - Name

Pavol

I.3 - Degrees

RNDr., PhD.

I.4 - Year of birth

1986

I.5 - Name of the workplace

Department of Physiology, Jessenius faculty of medicine in Martin, Comenius University in Bratislava

I.6 - Address of the workplace

Malá hora 4C, 03601 Martin

I.7 - Position

Assistant professor

I.8 - E-mail address

pavol.mikolka@uniba.sk

I.9 - Hyperlink to the entry of a person in the Register of university staff

https://www.portalvs.sk/regzam/detail/24992

I.10 - Name of the study field in which a person works at the university

Normal and pathological physiology

I.11 - ORCID iD

0000-0001-8485-4748

II. - Higher education and further qualification growth

II.1 - First degree of higher education

II.a - Name of the university or institution

Masaryk University

II.b - Year

2008

II.c - Study field and programme

Biology

II.2 - Second degree of higher education

II.a - Name of the university or institution

Masaryk University

II.b - Year

2010

II.c - Study field and programme

Biology

II.3 - Third degree of higher education

II.a - Name of the university or institution

Comenius University Bratislava

II.b - Year

2015

II.c - Study field and programme

Normal and pathological physiology

II.4 - Associate professor

II.5 - Professor

II.6 - Doctor of Science (DrSc.)

III. - Current and previous employment

III.a - Occupation-position	III.b - Institution	III.c - Duration
Researcher	Biomedical centre Martin, Jessenius faculty of medicine in Martin, Comenius University in Bratislava	2015 - 2021
Assistant professor	Department of Physiology, Jessenius faculty of medicine in Martin, Comenius University in Bratislava	2021 - present

IV. - Development of pedagogical, professional, language, digital and other skills

IV.a - Activity description, course name, other	IV.b - Name of the institution	IV.c - Year
State language exam in English	State Language School at the Business Academy, Martin	2015
Medical education course	Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava	2021
Innovative methodologies for teaching and learning	English Matters European ERASMUS+ Programme	2023

V. - Overview of activities within the teaching career at the university

V.1 - Overview of the profile courses taught in the current academic year according to study programmes

V.1.a - Name of the profile course	V.1.b - Study programme	V.1.c - Degree	V.1.d - Field of study
Physiology 1 and 2	General medicine	I.+II.	General Medicine
Physiology 1 and 2	Dental medicine	I.+II.	Dentistry, Dental Medicine

V.2 - Overview of the responsibility for the delivery, development and quality assurance of the study programme or its part at the university in the current academic year

V.3 - Overview of the responsibility for the development and quality of the field of habilitation procedure and inaugural procedure in the current academic year

V.4 - Overview of supervised final theses

V.4.1 - Number of currently supervised theses

V.4.b - Diploma (second degree)

V.4.c - Dissertation (third degree)

V.4.2 - Number of defended theses

V.4.b - Diploma (second degree)

V.5 - Overview of other courses taught in the current academic year according to study programmes

V.5.a - Name of the course	V.5.b - Study programme	V.5.c - Degree	V.5.d - Field of study
Anatomy and physiology	Nursing	I.	Nursing
Anatomy and physiology	Midwifery	I.	Midwifery
Anatomy and physiology	Public health	I.	Public health

VI. - Overview of the research/artistic/other outputs

VI.1 - Overview of the research/artistic/other outputs and the corresponding citations

VI.1.1 - Number of the research/artistic/other outputs

VI.1.a - Overall

235

VI.1.b - Over the last six years

VI.1.2 - Number of the research/artistic/other outputs registered in the Web of Science or Scopus databases

VI.1.a - Overall

VI.1.b - Over the last six years

VI.1.3 - Number of citations corresponding to the research/artistic/other outputs

VI.1.a - Overall

940

VI.1.b - Over the last six years

696

VI.1.4 - Number of citations registered in the Web of Science or Scopus databases

VI.1.a - Overall

940

VI.1.b - Over the last six years

696

VI.1.5 - Number of invited lectures at the international, national level

VI.2 - The most significant research/artistic/other outputs

Mikolka P, Kosutova P, Kolomaznik M, Nemcova N, Hanusrichterova J, Curstedt T, Johansson J, Calkovska A. The Synthetic Surfactant CHF5633 Restores Lung Function and Lung Architecture in Severe Acute Respiratory Distress Syndrome in Adult Rabbits. Lung. 2024 Jun;202(3):299-315. doi: 10.1007/s00408-024-00689-z

Mikolka P, Kronqvist N, Haegerstrand-Björkman M, et al. Synthetic surfactant with a combined SP-B and SP-C analogue is efficient in rabbit models of adult and neonatal respiratory distress syndrome [published online ahead of print, 2023 Jul 26]. Transl Res. 2023;S1931-5244(23)00127-5. doi:10.1016/j.trsl.2023.07.009

Kosutova P, Mikolka P, Mokra D, Calkovska A. Anti-inflammatory activity of non-selective PDE inhibitor aminophylline on the lung tissue and respiratory parameters in animal model of ARDS. J Inflamm (Lond). 2023;20(1):10. Published 2023 Mar 16. doi:10.1186/s12950-023-00337-y

Mikolka P, Curstedt T, Feinstein R, Larsson A, Grendar M, Rising A, Johansson J. Impact of synthetic surfactant CHF5633 with SP-B and SP-C analogues on lung function and inflammation in rabbit model of acute respiratory distress syndrome. Physiol Rep. 2021 Jan;9(1):e14700. doi: 10.14814/phy2.14700. PMID: 33403805; PMCID: PMC7786196

Zebialowicz Ahlström J, Massaro F, Mikolka P, Feinstein R, Perchiazzi G, Basabe-Burgos O, Curstedt T, Larsson A, Johansson J, Rising A. Synthetic surfactant with a recombinant surfactant protein C analogue improves lung function and attenuates inflammation in a model of acute respiratory distress syndrome in adult rabbits. Respir Res. 2019 Nov 6;20(1):245. doi: 10.1186/s12931-019-1220-x. PMID: 31694668; PMCID: PMC6836435

VI.3 - The most significant research/artistic/other outputs over the last six years

Kosutova P, Kolomaznik M, Calkovska A, Mokra D, Mikolka P. Nitric-Oxide-Releasing Dexamethasone Derivative NCX-1005 Improves Lung Function and Attenuates Inflammation in Experimental Lavage-Induced ARDS. Pharmaceutics. 2021 Dec 5;13(12):2092. doi: 10.3390/pharmaceutics13122092. PMID: 34959373; PMCID: PMC8703685

Mikolka P, Kosutova P, Kolomaznik M, et al. Efficacy of surfactant therapy of ARDS induced by hydrochloric acid aspiration followed by ventilator-induced lung injury - an animal study. Physiol Res. 2022;71(S2):S237-S249. doi:10.33549/physiolres.935003

VI.4 - The most significant citations corresponding to the research/artistic/other outputs

Herman L, De Smedt SC, Raemdonck K. Pulmonary surfactant as a versatile biomaterial to fight COVID-19. J Control Release. 2022 Feb;342:170-188. doi: 10.1016/j.jconrel.2021.11.023. Epub 2021 Nov 20. PMID: 34813878; PMCID: PMC8605818. IF - JCR: 2020 - 9.776. Q1 - Pharmacology & pharmacy.

Esquer C, Echeagaray O, Firouzi F, Savko C, Shain G, Bose P, Rieder A, Rokaw S, Witon-Paulo A, Gude N, Sussman MA. Fundamentals of vaping-associated pulmonary injury leading to severe respiratory distress. Life Sci Alliance. 2021 Nov 22;5(2):e202101246. doi: 10.26508/lsa.202101246. PMID: 34810278; PMCID: PMC8616545. IF - JCR: 2020 - 4.591. Q1 - Biology.

Fouladseresht H, Doroudchi M, Rokhtabnak N, Abdolrahimzadehfard H, Roudgari A, Sabetian G, Paydar S. Predictive monitoring and therapeutic immune biomarkers in the management of clinical complications of COVID-19. Cytokine Growth Factor Rev. 2021 Apr;58:32-48. doi: 10.1016/j.cytogfr.2020.10.002. Epub 2020 Oct 9. PMID: 33199179; PMCID: PMC7544568. IF - JCR: 2020 - 7.638. Q1 - Biochemistry & molecular biology.

Piva S, DiBlasi RM, Slee AE, Jobe AH, Roccaro AM, Filippini M, Latronico N, Bertoni M, Marshall JC, Portman MA. Surfactant therapy for COVID-19 related ARDS: a retrospective case-control pilot study. Respir Res. 2021 Jan 18;22(1):20. doi: 10.1186/s12931-020-01603-w. PMID: 33461535; PMCID: PMC7812332. IF - JCR: 2020 - 5.631. Q1 - Respiratory system.

Efferth T, Oesch F. The immunosuppressive activity of artemisinin-type drugs towards inflammatory and autoimmune diseases. Med Res Rev. 2021 Nov;41(6):3023-3061. doi: 10.1002/med.21842. Epub 2021 Jul 21. PMID: 34288018. IF - JCR: 2020 - 12.944. Q1 - Pharmacology & pharmacy.

VI.5 - Participation in conducting (leading) the most important research projects or art projects over the last six years

VEGA 1/0026/25 Efficacy of a synthetic surfactant with a combined SP-B and SP-C peptide in an experimental model of respiratory distress syndrome - vedúci projektu

VEGA 1/0097/23 Dual insult and lung injury: a clinically relevant model for testing the effect of exogenous surfactant? - researcher

VEGA 1/0004/21 Synthetic surfactant with surfactant analogues SP-B and SP-C and anti-inflammatory therapy in experimental acute respiratory distress syndrome (ARDS) - principal investigator

VEGA 1/0055/19 Pulmonary surfactant as part of the defense mechanisms of the respiratory system: the use of three models - researcher

VEGA 1/0356/18 The effect of experimentally induced lung injury on extrapulmonary organs - researcher

APVV-17-0250 Pulmonary surfactant as a modulator of the organism's response to endotoxin exposure: effects and mechanisms - researcher

VII. - Overview of organizational experience related to higher education and research/artistic/other activities

VIII. - Overview of international mobilities and visits oriented on education and research/artistic/other activities in the given field of study

VIII.a - Name of the institution	VIII.b - Address of the institution	VIII.c - Duration (indicate the duration of stay)	VIII.d - Mobility scheme, employment contract, other (describe)
Karolinska Institutet	Karolinska Institutet, 171 77 Stockholm, Sweden	1.5.2022 - 31.7.2022	Scientific intership
Karolinska Institutet	Karolinska Institutet, 171 77 Stockholm, Sweden	1.11.2017 - 31.12.2018	Postdoctoral internship
Medical University of Vienna	Spitalgasse 23, 1090 Wien, Austria	1.9.2013 - 28.2.2014	Scientific intership
Masaryk University	Žerotínovo nám. 617/9, 601 77 Brno, Czech Republic	1.7.2010 - 31.5.2011	Employment contract

IX. - Other relevant facts

Date of last update

2025-02-26

Name and surname:	RNDr. Pavol Mikolka, PhD.
Document type:	Research/art/teacher profile of a person
The name of the university:	Comenius University Bratislava
The seat of the university:	Šafárikovo námestie 6, 818 06 Bratislava