I. - Basic information

I.1 - Surname

Lučanský

I.2 - Name

Vincent

I.3 - Degrees

RNDr., PhD.

I.4 - Year of birth

1979

I.5 - Name of the workplace

Institute of Pathological Physiology, JFMED UK

I.6 - Address of the workplace

Malá Hora 4C, 036 01, Martin

I.7 - Position

Researcher

I.8 - E-mail address

vincent.lucansky@uniba.sk

I.10 - Name of the study field in which a person works at the university

Medical biology

I.11 - ORCID iD

https://orcid.org/0000-0003-2321-4573

II. - Higher education and further qualification growth

II.1 - First degree of higher education

II.2 - Second degree of higher education

II.a - Name of the university or institution

University of Pavol Jozef Šafárik, Košice

II.b - Year

2002

II.c - Study field and programme

Molecular biology

II.3 - Third degree of higher education

II.a - Name of the university or institution

Charles University, Prague

II.b - Year

2010

II.c - Study field and programme

Cell and Molecular Biology, Genetics and Virology

II.4 - Associate professor

II.5 - Professor

II.6 - Doctor of Science (DrSc.)

III. - Current and previous employment

III.a - Occupation-position	III.b - Institution	III.c - Duration
Researcher	JF MED UK, Martin	2018-Present
Research engineer	INSERM, Strasbourg, FR	2016-2018
Post doc	DKFZ, Heidelberg, GER	2012-2014
Research associate / Ph.D. student	IHBT, Prague, CZ	2002-2012

IV. - Development of pedagogical, professional, language, digital and other skills

IV.a - Activity description, course name, other	IV.b - Name of the institution	IV.c - Year
Research internship	CNRS, IRIM, Montpellier, France	2020
Pedagogical minimum course	University of Pavol Jozef Šafárik	2001-2002
Language school - English

V. - Overview of activities within the teaching career at the university

V.1 - Overview of the profile courses taught in the current academic year according to study programmes

V.1.a - Name of the profile course	V.1.b - Study programme	V.1.c - Degree	V.1.d - Field of study
Medical biology			General medicine

V.2 - Overview of the responsibility for the delivery, development and quality assurance of the study programme or its part at the university in the current academic year

V.3 - Overview of the responsibility for the development and quality of the field of habilitation procedure and inaugural procedure in the current academic year

V.4 - Overview of supervised final theses

V.4.1 - Number of currently supervised theses

V.4.2 - Number of defended theses

V.5 - Overview of other courses taught in the current academic year according to study programmes

VI. - Overview of the research/artistic/other outputs

VI.1 - Overview of the research/artistic/other outputs and the corresponding citations

VI.1.1 - Number of the research/artistic/other outputs

VI.1.a - Overall

Articles in journals with IF, articles in journals without IF, abstracts, preprints, etc.: 24 + 1 accepted, 3, 4, 1, thus total: 33

VI.1.b - Over the last six years

Articles in journals with IF, articles in journals without IF, abstracts, preprints, etc.: 17 + 1 accepted, 3, 1, thus total: 22

VI.1.2 - Number of the research/artistic/other outputs registered in the Web of Science or Scopus databases

VI.1.a - Overall

24 + 1 received, total: 25

VI.1.b - Over the last six years

17 + 1 received, total: 18

VI.1.3 - Number of citations corresponding to the research/artistic/other outputs

VI.1.a - Overall

Google scholar: 314, Research gate: 272, 23.01. 2025

VI.1.b - Over the last six years

Google scholar: 251, Research gate: 228, 23.01. 2025

VI.1.4 - Number of citations registered in the Web of Science or Scopus databases

VI.1.a - Overall

Scopus: 227, 23.01. 2025

VI.1.b - Over the last six years

Scopus: 184, 23.01. 2025

VI.1.5 - Number of invited lectures at the international, national level

VI.2 - The most significant research/artistic/other outputs

LC3B conjugation machinery promotes autophagy-independent HIV-1 entry in CD4+ T lymphocytes.

Pradel B, Cantaloube G, Villares M, Deffieu MS, Robert-Hebmann V, Lucansky V, Faure M, Chazal N, Gaudin R, Espert L.

Autophagy. 2024 Apr 7:1-12. doi: 10.1080/15548627.2024.2338573. Online ahead of print. PMID: 38566318

IF: 13,3

Comparison of the methods for isolation and detection of SARS-CoV-2 RNA in municipal wastewater.

Lucansky V, Samec M, Burjanivova T, Lukacova E, Kolkova Z, Holubekova V, Turyova E, Hornakova A, Zaborsky T, Podlesniy P, Reizigova L, Dankova Z, Novakova E, Pecova R, Calkovska A, Halasova E.

Front Public Health. 2023 Mar 7;11:1116636. doi: 10.3389/fpubh.2023.1116636. eCollection 2023. PMID: 36960362

IF: 5,2

Occludin stalls HCV particle dynamics apart from hepatocyte tight junctions, promoting virion internalization.

Deffieu MS, Clément CMH, Dorobantu CM, Partiot E, Bare Y, Faklaris O, Rivière B, Ayala-Nunez NV, Baumert TF, Rondé P, Mély Y, Lucansky V, Gaudin R.

Hepatology. 2022 Oct;76(4):1164-1179. doi: 10.1002/hep.32514. Epub 2022 Jun 10. PMID: 35388524

IF: 17,3

Rab7-harboring vesicles are carriers of the transferrin receptor through the biosynthetic secretory pathway.

Deffieu MS, Cesonyte I, Delalande F, Boncompain G, Dorobantu C, Song E, Lucansky V, Hirschler A, Cianferani S, Perez F, Carapito C, Gaudin R.

Sci Adv. 2021 Jan 8;7(2):eaba7803. doi: 10.1126/sciadv.aba7803. Print 2021 Jan. PMID: 33523982

IF: 14,1

Hypoxia-induced human deoxyribonuclease I is a cellular restriction factor of hepatitis B virus.

Hallez C, Li X, Suspène R, Thiers V, Bouzidi MS, M Dorobantu C, Lucansky V, Wain-Hobson S, Gaudin R, Vartanian JP.

Nat Microbiol. 2019 Jul;4(7):1196-1207. doi: 10.1038/s41564-019-0405-x. Epub 2019 Apr 1. PMID: 30936483

IF: 15,5

VI.3 - The most significant research/artistic/other outputs over the last six years

LC3B conjugation machinery promotes autophagy-independent HIV-1 entry in CD4+ T lymphocytes.

Pradel B, Cantaloube G, Villares M, Deffieu MS, Robert-Hebmann V, Lucansky V, Faure M, Chazal N, Gaudin R, Espert L.

Autophagy. 2024 Apr 7:1-12. doi: 10.1080/15548627.2024.2338573. Online ahead of print. PMID: 38566318

IF: 13,3

Comparison of the methods for isolation and detection of SARS-CoV-2 RNA in municipal wastewater.

Lucansky V, Samec M, Burjanivova T, Lukacova E, Kolkova Z, Holubekova V, Turyova E, Hornakova A, Zaborsky T, Podlesniy P, Reizigova L, Dankova Z, Novakova E, Pecova R, Calkovska A, Halasova E.

Front Public Health. 2023 Mar 7;11:1116636. doi: 10.3389/fpubh.2023.1116636. eCollection 2023. PMID: 36960362

IF: 5,2

Occludin stalls HCV particle dynamics apart from hepatocyte tight junctions, promoting virion internalization.

Deffieu MS, Clément CMH, Dorobantu CM, Partiot E, Bare Y, Faklaris O, Rivière B, Ayala-Nunez NV, Baumert TF, Rondé P, Mély Y, Lucansky V, Gaudin R.

Hepatology. 2022 Oct;76(4):1164-1179. doi: 10.1002/hep.32514. Epub 2022 Jun 10. PMID: 35388524

IF: 17,3

Rab7-harboring vesicles are carriers of the transferrin receptor through the biosynthetic secretory pathway.

Deffieu MS, Cesonyte I, Delalande F, Boncompain G, Dorobantu C, Song E, Lucansky V, Hirschler A, Cianferani S, Perez F, Carapito C, Gaudin R.

Sci Adv. 2021 Jan 8;7(2):eaba7803. doi: 10.1126/sciadv.aba7803. Print 2021 Jan. PMID: 33523982

IF: 14,1

Targeting monocytic Occludin impairs transendothelial migration and HIV neuroinvasion.

Brychka D, Ayala-Nunez NV, Dupas A, Bare Y, Partiot E, Mittelheisser V, Lucansky V, Goetz JG, Osmani N, Gaudin R.

EMBO Rep. 2024 Aug;25(8):3276-3299. doi: 10.1038/s44319-024-00190-x. Epub 2024 Jul 22. PMID: 39039298

IF: 6,5

VI.4 - The most significant citations corresponding to the research/artistic/other outputs

Hypoxia-induced human deoxyribonuclease I is a cellular restriction factor of hepatitis B virus

Cited in:

Hypoxia signaling in human health and diseases: implications and prospects for therapeutics

Luo, Z. et al., 2022 Signal Transduction and Targeted Therapy 7(1),218

IF: 39,3

Hypoxia-induced human deoxyribonuclease I is a cellular restriction factor of hepatitis B virus

Cited in:

Hypoxia inducible factors regulate hepatitis B virus replication by activating the basal core promoter

Wing, P.A.C. et al., 2021 Journal of Hepatology 75(1), pp. 64-73

IF: 30,1

Rab7-harboring vesicles are carriers of the transferrin receptor through the biosynthetic secretory pathway

Cited in:

BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2

Samelson, A.J. et al., 2022 Nature Cell Biology 24(1), pp. 24-34

IF: 28,2

Hypoxia-induced human deoxyribonuclease I is a cellular restriction factor of hepatitis B virus

Cited in:

N4-Acetylcytidine Drives Glycolysis Addiction in Gastric Cancer via NAT10/SEPT9/HIF-1α Positive Feedback Loop

Yang, Q. et al., 2023 Advanced Science 10(23),2300898

IF: 15,1

Occludin stalls HCV particle dynamics apart from hepatocyte tight junctions, promoting virion internalization

Cited in:

Viruses and phospholipids: Friends and foes during infection

Rattay, S. et al., 2023 Journal of Medical Virology 95(3),e28658

IF: 12,7

VI.5 - Participation in conducting (leading) the most important research projects or art projects over the last six years

Identification of new potential targets in the treatment of CRC using a combination of RNAseq and CRISPR/Cas9 technology.

Support scheme no. 368/2015 for the return of the experts

Main investigator

2018-2019

Travel grant awarded by the French Embassy in Slovakia

CNRS/IRIM Montpellier

Main investigator

2020

Preparation of molecular tools for imaging spatiotemporal dynamics of SARS-CoV-2 cell entry using high-resolution 3D microscopy in real-time.

VEGA 1-0261-22

Main investigator

2022-2024

CovLab: Operational program Integrated infrastructure for the project New possibilities of laboratory diagnostics and massive screening of SARS-CoV-2 and identification of mechanisms of virus behavior in the human organism, ITMS: 313011AUA4, co-financed by the European Regional Development Fund Co-investigator.

Author of the section dealing with the epidemiology of Sars-CoV-2 in wastewater.

2020-2023

VII. - Overview of organizational experience related to higher education and research/artistic/other activities

VIII. - Overview of international mobilities and visits oriented on education and research/artistic/other activities in the given field of study

VIII.a - Name of the institution	VIII.b - Address of the institution	VIII.c - Duration (indicate the duration of stay)	VIII.d - Mobility scheme, employment contract, other (describe)
CNRS / IRIM (Centre national de la recherche scientifique / Institut de Recherche en Infectiology de Montpellier)	IRIM, UMR 9004 – CNRS / UM, 1919 route de Mende, 34293 Montpellier FRANCE	October-December 2020	Internship / Travel grant of the French Embassy in Slovakia
CNRS / IRIM (Centre national de la recherche scientifique / Institut de Recherche en Infectiology de Montpellier)	IRIM, UMR 9004 – CNRS / UM, 1919 route de Mende, 34293 Montpellier FRANCE	June 2024	Visit of collaborating lab

IX. - Other relevant facts

IX.a - If relevant, other activities related to higher education or research/artistic/other activities are mentioned

Since 2023: Editor "Cell Biochemistry & Function” (Wiley) https://analyticalsciencejournals.onlinelibrary.wiley.com/hub/journal/10990844/homepage/editorialboard.html

Since 2023: Acta virologica / Frontiers / Reviewer / https://www.frontierspartnerships.org/journals/acta-virologica/editors

Name and surname:	RNDr. Vincent Lučanský, PhD.
Document type:	Research/art/teacher profile of a person
The name of the university:	Comenius University Bratislava
The seat of the university:	Šafárikovo námestie 6, 818 06 Bratislava