KOVALSKÁ, Mária – KOVALSKÁ, Libuša – PAVLÍKOVÁ, Martina – JANÍČKOVÁ, Mária – MIKUŠKOVÁ, Katarína – ADAMKOV, Marian – KAPLÁN, Peter – TATARKOVÁ, Zuzana – LEHOTSKÝ, Ján. Intracellular signaling MAPK pathway after cerebral ischemia-reperfusion injury. In Neurochemical Research 2012, vol. 37, no. 7, p. 1568-1577. (2012: 2.125 – IF, Q3 – JIF); Citations (76)

KOVALSKÁ, Mária – KOVALSKÁ, Libuša – MIKUŠKOVÁ, Katarína – ADAMKOV, Marian – TATARKOVÁ, Zuzana – LEHOTSKÝ, Ján. P-ERK involvement in the neuroprotection exerted by ischemic preconditioning in rat hippocampus subjected to four vessel occlusion. In Journal of Physiology and Pharmacology 2014, vol. 65, no. 6, p. 767-776. (2014: 2.386 – IF, Q2– JIF); Citations (16)

PETRÁŠ, Martin – TATARKOVÁ, Zuzana – KOVALSKÁ, Mária – MOKRÁ, Daniela – DOBROTA, Dušan – LEHOTSKÝ, Ján – DRGOVÁ, Anna. Hyperhomocysteinemia as a risk factor for the neuronal system disorders. In Journal of Physiology and Pharmacology 2014, vol. 65, no. 1, p. 15-23. (2014: 2.386 – IF,  Q2 – JIF); Citations (88)

KOVALSKÁ, Mária – TÓTHOVÁ, Barbara – KOVALSKÁ, Libuša – TATARKOVÁ, Zuzana – KALENSKÁ, Dagmar – TOMAŠCOVÁ, Anna –ADAMKOV, Marian – LEHOTSKÝ, Ján. Association of Induced Hyperhomocysteinemia with Alzheimer's Disease-Like Neurodegeneration in Rat Cortical Neurons After Global Ischemia-Reperfusion Injury. In Neurochemical Research 2018, vol. 43, no. 9, p. 1766-1778. (2018: 2.782 – IF, Q3 – JIF ; Q1 – Scimago); Citations (20)

LEHOTSKÝ, Ján – TÓTHOVÁ, Barbara – KOVALSKÁ, Mária – DOBROTA, Dušan – TOMAŠCOVÁ, Anna – KALENSKÁ, Dagmar – KAPLÁN, Peter: Role of Homocysteine inthe Ischemic Stroke and Development of Ischemic Tolerance. In Frontiers in Neuroscience 2016, vol. 10, p. 1-16, art. no. 538. (2016: 3.566 – IF, Q2 – JIF); Citations (95)

KOVALSKÁ, Mária – HNILICOVÁ, Petra – KALENSKÁ, Dagmar – TÓTHOVÁ, Barbara – ADAMKOV, Marian – LEHOTSKÝ, Ján. Effect of Methionine Diet on Metabolic and Histopathological Changes of Rat Hippocampus. In International Journal of Molecular Sciences, 2019, vol. 20, no. 24, p. 1-16. (2019: 4.556 – IF, Q1 – JIF, Q2 – Scimago); Citations (7)

ŽIAKOVÁ, Katarína – KOVALSKÁ, Mária – CHOMOVÁ, Mária – PILCHOVÁ, Ivana – TATARKOVÁ, Zuzana – KAPLÁN, Peter – RAČAY, Peter. Global brain ischemia in rats is associated with mitochondrial release and downregulation of Mfn2 in the cerebral cortex, but not the hippocampus. In International Journal of Molecular Medicine 2019, vol. 43, no. 6, p. 2420-2428. (2019: 3.098 – IF, Q3– JIF, Q1 – Scimago); Citations (18)

KOVALSKÁ, Mária – HNILICOVÁ, Petra – KALENSKÁ, Dagmar – TOMAŠCOVÁ, Anna – ADAMKOV, Marian – LEHOTSKÝ, Ján: Effect of Methionine Diet onTime-Related Metabolic and Histopathological Changes of Rat Hippocampus in the Model of Global Brain Ischemia. In Biomolecules, 2020, vol. 10, no. 8, p. 1-21. (2020: 4.879 – IF, Q2 – JIF, Q2 – Scimago); Citations (8)

KOVALSKÁ, Mária – BARANOVIČOVÁ, Eva – KALENSKÁ, Dagmar – TOMAŠCOVÁ, Anna – ADAMKOV, Marian – KOVALSKÁ, Libuša – LEHOTSKÝ, Ján: Methionine Diet Evoked Hyperhomocysteinemia Causes Hippocampal Alterations, Metabolomics Plasma Changes and Behavioral Pattern in Wild Type Rats. In IJMS, 2021, vol. 22, no. 9, p. 1-15. (2021: 6.208 – IF, Q1 – JIF, Q1 – Scimago); Citations (9)

KOVALSKA, Maria – HNILICOVA, Petra – KALENSKA, Dagmar – ADAMKOV, Marian – KOVALSKA, Libusa – LEHOTSKY, Jan. Alzheimer's Disease-like Pathological Features in the Dorsal Hippocampus of Wild-Type Rats Subjected to Methionine-Diet-Evoked Mild Hyperhomocysteinaemia. In Cells 2023, vol. 12, no.16, p. 1-21, art. no 2087. (2023: 5.1 – IF, Q2– JIF, Q1 – Scimago); Citations (2)

KOVALSKÁ, Mária – KOVALSKÁ, Libuša – PAVLÍKOVÁ, Martina – JANÍČKOVÁ, Mária – MIKUŠKOVÁ, Katarína – ADAMKOV, Marian – KAPLÁN, Peter – TATARKOVÁ, Zuzana – LEHOTSKÝ, Ján. Intracellular signaling MAPK pathway after cerebral ischemia-reperfusion injury. In Neurochemical Research 2012, vol. 37, no. 7, p. 1568-1577. (2012: 2.125 – IF, Q3 – JIF); Ohlasy (76). Cited in: 2024 [01/20] / FRA – Wang, Yuqi – Wang, Shuhui – Wang, Yanhang – Gao, Peng – Wang, Le – Wang, Qiqi – Zhang, Yun – Liu, Kechun – Xia, Qing – Tu, Pengfei. The natural compound sinometumine E derived from Corydalis decumbens promotes angiogenesis by regulating HIF-1/ VEGF pathway in vivo and in vitro. In Biomedicine & pharmacotherapy. Paris: Elsevier, 2024, no. 178, art. no. 117113 – SCO (2024: 6.9 – IF, Q1 – JIF).

PETRÁŠ, Martin – TATARKOVÁ, Zuzana – KOVALSKÁ, Mária – MOKRÁ, Daniela – DOBROTA, Dušan – LEHOTSKÝ, Ján – DRGOVÁ, Anna. Hyperhomocysteinemia as a risk factor for the neuronal system disorders. In Journal of Physiology and Pharmacology 2014, vol. 65, no. 1, p. 15-23. (2014: 2.386 – IF,  Q2 – JIF). Ohlasy (88). Cited in: 2024 [01/20] / USA – Li, Xiaozhong – Zhou, Zheng – Tao, Yu – He, Lei – Zhan, Fenfang – Li, Juxiang. Linking homocysteine and ferroptosis in cardiovascular disease: insights and implications. In Apoptosis: An International Journal on Programmed Cell Death. New York: Springer Nature. Springer International Publishing AG, 2024, vol. 29, p. 1944-1958 – SCO; CCC; WOS CC; SCIE (2024: 5.561 – IF, Q1 – JIF).

KOVALSKÁ, Mária – TÓTHOVÁ, Barbara – KOVALSKÁ, Libuša – TATARKOVÁ, Zuzana – KALENSKÁ, Dagmar – TOMAŠCOVÁ, Anna – ADAMKOV, Marian – LEHOTSKÝ, Ján. Association of Induced Hyperhomocysteinemia with Alzheimer's Disease-Like Neurodegeneration in Rat Cortical Neurons After Global Ischemia-Reperfusion Injury. In Neurochemical Research 2018, vol. 43, no. 9, p. 1766-1778. (2018: 2.782 – IF, Q3 – JIF; Q1 – Scimago). Ohlasy (20). Cited in: 2021 [01/20] / CHE – Pluta, Ryszard – Czuczwar, Stanisław Jerzy – Januszewski, Sławomir – Jabłoński, Mirosław. The many faces of post-ischemic tau protein in brain neurodegeneration of the Alzheimer’s disease type. In Cells. Bazilej: Multidisciplinary Digital Publishing Institute, 2021, vol. 10, no. 9, art. no. 2213 – SCO; WOS CC; SCIE (2021: 7.666 – IF, Q1 – JIF).

KOVALSKÁ, Mária – HNILICOVÁ, Petra – KALENSKÁ, Dagmar – TOMAŠCOVÁ, Anna – ADAMKOV, Marian – LEHOTSKÝ, Ján: Effect of Methionine Diet onTime-Related Metabolic and Histopathological Changes of Rat Hippocampus in the Model of Global Brain Ischemia. In Biomolecules, 2020, vol. 10, no. 8, p. 1-21. (2020: 4.879 – IF, Q2 – JIF, Q2 – Scimago). Ohlasy (8). Cited in: 2021 [01/12] / CHE – Nieraad, Hendrik – Pannwitz, Nina – de Bruin, Natasja – Geisslinger, Gerd – Till, Uwe. Hyperhomocysteinemia: Metabolic role and animal studies with a focus on cognitive performance and decline—a review. In Biomolecules. Basel: Multidisciplinary Digital Publishing Institute, 2021, vol. 11, no. 10, art. no. 1546 – SCO; WOS CC; SCIE (2021: 4.231 – IF, Q2 – JIF).

KOVALSKÁ, Mária – BARANOVIČOVÁ, Eva – KALENSKÁ, Dagmar – TOMAŠCOVÁ, Anna – ADAMKOV, Marian – KOVALSKÁ, Libuša – LEHOTSKÝ, Ján: Methionine Diet Evoked Hyperhomocysteinemia Causes Hippocampal Alterations, Metabolomics Plasma Changes and Behavioral Pattern in Wild Type Rats. In IJMS, 2021, vol. 22, no. 9, p. 1-15. (2021: 6.208 – IF, Q1 – JIF, Q1 – Scimago). Ohlasy (9). Cited in: 2022 [01/20] / CHE – Pluta, Ryszard. Ischemic Brain Neurodegeneration. In International journal of molecular sciences. Bazilej: Multidisciplinary Digital Publishing Institute, 2022, vol. 23, no. 12, art. no. 6441, p.1422-0067 – WOS CC; CCC; SCO (2022: 5.6 – IF, Q1– JIF).

VEGA 1/0229/15: Study of the association of induced hyperhomocysteinemia with the progression of neurodegenerative changes under experimental conditions (Responsible Researcher) 2015-2017: Despite of intensive research, whether in clinical or experimental medicine, it is not entirely clear whether hHcy can be considered a risk factor for AD. A better understanding of the nature of the mechanisms involved in stroke in association with hHcy could in the future help to streamline postoperative therapy in connection with neurodegenerative changes in the brain as well as the development of AD-type dementia.

https://www.jfmed.uniba.sk/fileadmin/jlf/Dekanat/Sekretariat/Vyrocne_spravy_o_cinnosti/3._Vyrocna_sprava_o_cinnosti_2016_-_komplet.pdf

VEGA 1/0171/18: Influence of induced hyperhomocysteinemia on progression of neuropathological changes with Alzheimer-like features in the experimental model (Responsible Researcher). 2018-2022: The clinical significance of hHcy in the development of stroke and in the prediction of mortality and the development of neurodegeneration has been demonstrated in many studies. In spite of mentioned above, the exact role of hHcy as a independent risk factor for AD is not clear. Elucidation of those mechanisms in ischemic brain a as well as in other key organs could in the future contribute to the streamlining of therapy resp. prevention in patients after ischemic stroke in connection with a disorder of essential amino acid metabolism (as for e.g. hHcy) as well as in the development of cerebrovascular dementia or AD-type dementia.

https://www.jfmed.uniba.sk/fileadmin/jlf/Dekanat/Sekretariat/Vyrocne_spravy_o_cinnosti/1_KONECNA_VERZIA_Vyrocna_sprava_o_cinnosti_2019.pdf

VEGA 1/0192/22: Induced hyperhomocysteinemia and its influence on the development of metabolic and neuro histopathological changes in an experimental model of cerebral ischemia (Responsible Researcher). 2022-2024: Metabolic disorders caused by improper diet represent a severe risk factor for the occurrence and development of stroke and subsequent neurodegeneration. Deepening the knowledge about the mechanisms taking place in critical tissues during ischemia and after reperfusion in hyperhomocysteinemic conditions could contribute to a better understanding of the pathomechanism of development, cause, potential prevention or improving the effectiveness of therapy in patients after cerebral ischemia in connection with a disorder of the metabolism of essential amino acids as well as in the development of cerebrovascular dementia, which is a frequent and little-researched condition in clinical practice.

Hodnotiaca_sprava_o_urovni_VVC_2022_VR_JLF_UK.pdf (uniba.sk)