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Name and surname:
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RNDr. Petra Košútová, PhD.
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Document type:
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Research/art/teacher profile of a person
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The name of the university:
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Comenius University Bratislava
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The seat of the university:
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Šafárikovo námestie 6, 818 06 Bratislava
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| III.a - Occupation-position | III.b - Institution | III.c - Duration |
|---|---|---|
| researcher | Jessenius Faculty of Medicine in Martin | 2017 |
| V.1.a - Name of the profile course | V.1.b - Study programme | V.1.c - Degree | V.1.d - Field of study |
|---|---|---|---|
| Physiology | General Medicine | I.+II. | General Medicine |
Košutova P, Mikolka P. Aspiration syndromes and associated lung injury: incidence, pathophysiology and management. Physiol Res. 2021 Dec 30;70(Suppl4):S567-S583. doi: 10.33549/physiolres.934767. PMID: 35199544; PMCID: PMC9054185.
Kosutova P, Mikolka P, Mokra D, Calkovska A. Anti-inflammatory activity of non-selective PDE inhibitor aminophylline on the lung tissue and respiratory parameters in animal model of ARDS. J Inflamm (Lond). 2023 Mar 16;20(1):10. doi: 10.1186/s12950-023-00337-y. PMID: 36927675; PMCID: PMC10018984.
Kosutova P, Mikolka P, Balentova S, Adamkov M, Calkovska A, Mokra D. Effects of PDE3 Inhibitor Olprinone on the Respiratory Parameters, Inflammation, and Apoptosis in an Experimental Model of Acute Respiratory Distress Syndrome. Int J Mol Sci. 2020 May 11;21(9):3382. doi: 10.3390/ijms21093382. PMID: 32403267; PMCID: PMC7247002.
Kosutova P, Mikolka P, Balentova S, Kolomaznik M, Adamkov M, Mokry J, Calkovska A, Mokra D. Effects of phosphodiesterase 5 inhibitor sildenafil on the respiratory parameters, inflammation and apoptosis in a saline lavage-induced model of acute lung injury. J Physiol Pharmacol. 2018 Oct;69(5). doi: 10.26402/jpp.2018.5.15. Epub 2019 Jan 21. PMID: 30683832.
Kosutova P, Mikolka P, Kolomaznik M, Balentova S, Adamkov M, Calkovska A, Mokra D. Reduction of lung inflammation, oxidative stress and apoptosis by the PDE4 inhibitor roflumilast in experimental model of acute lung injury. Physiol Res. 2018 Dec 31;67(Suppl 4):S645-S654. doi: 10.33549/physiolres.934047. PMID: 30607971.
Kosutova P, Mikolka P, Balentova S, Adamkov M, Calkovska A, Mokra D. Effects of PDE3 Inhibitor Olprinone on the Respiratory Parameters, Inflammation, and Apoptosis in an Experimental Model of Acute Respiratory Distress Syndrome. Int J Mol Sci. 2020 May 11;21(9):3382. doi: 10.3390/ijms21093382. PMID: 32403267; PMCID: PMC7247002.
Kosutova P, Kolomaznik M, Calkovska A, Mokra D, Mikolka P. Nitric-Oxide-Releasing Dexamethasone Derivative NCX-1005 Improves Lung Function and Attenuates Inflammation in Experimental Lavage-Induced ARDS. Pharmaceutics. 2021 Dec 5;13(12):2092. doi: 10.3390/pharmaceutics13122092. PMID: 34959373; PMCID: PMC8703685.
Kosutova P, Nemcova N, Kolomaznik M, Mokra D, Calkovska A, Mikolka P. Time-Dependent Oxidative Alterations in Plasma and Lung Tissue after Meconium Aspiration in a Rabbit Model. Antioxidants (Basel). 2022 Dec 25;12(1):37. doi: 10.3390/antiox12010037. PMID: 36670899; PMCID: PMC9854924.
Kosutova P, Mikolka P, Mokra D, Calkovska A. Anti-inflammatory activity of non-selective PDE inhibitor aminophylline on the lung tissue and respiratory parameters in animal model of ARDS. J Inflamm (Lond). 2023 Mar 16;20(1):10. doi: 10.1186/s12950-023-00337-y. PMID: 36927675; PMCID: PMC10018984.
Košútová P, Nemcová N, Kolomazník M, Čalkovská A, Mikolka P. A novel rabbit model of severe ARDS: Synergistic effects of acid aspiration and harmful mechanical ventilation. Transl Res. 2025 Jul;281:43-54. doi: 10.1016/j.trsl.2025.05.009. Epub 2025 May 29. PMID: 40449621.
Walther FJ, Waring AJ. Moving on from clinical animal-derived surfactants to peptide-based synthetic pulmonary surfactant. Am J Physiol Lung Cell Mol Physiol. 2024;327(6):L883-L889.
Ocrospoma S, Restrepo MI. Severe aspiration pneumonia in the elderly. J Intensive Med. 2024;4(3):307-317. Published 2024 Apr 10.
Mir M, Chen J, Patel A, et al. Bioimpedance measurements of fibrotic and acutely injured lung tissues. Acta Biomater. Published online January 25, 2025.
Xu Z, Zhang G, Zhang X, et al. Menstrual blood-derived endometrial stem cells inhibit neuroinflammation by regulating microglia through the TLR4/MyD88/NLRP3/Casp1 pathway. Int J Biochem Cell Biol. 2023;157:106386.
R2 project Combination of anti-inflammatory and antioxidant therapy with surfactant attenuates ventilator- and hyperoxia-induced lung injury in immature rabbits - project leader
VEGA 1/0026/25 Efficacy of synthetic surfactant with combined SP-B and SP-C peptide in an experimental model of respiratory distress syndrome - investigator
VEGA No. 1/0004/21 Synthetic surfactant with analogues of surfactant proteins SP-B and SP-C and anti-inflammatory therapy in experimental acute respiratory distress syndrome (ARDS).- investigator
VEGA 1/0131/22 The influence of gender differences and asthma endotypes on the effectiveness of treatment in experimental models of bronchial asthma - investigator