Research/art/teacher profile of a person
Name and surname:
doc. MUDr. Milan Grofik, PhD.
Document type:
Research/art/teacher profile of a person
The name of the university:
Comenius University Bratislava
The seat of the university:
Šafárikovo námestie 6, 818 06 Bratislava

I. - Basic information

I.1 - Surname
Grofik
I.2 - Name
Milan
I.3 - Degrees
M.D., PhD.Asst.prof
I.4 - Year of birth
1973
I.5 - Name of the workplace
Clinic of Neurology, Jessenius Faculty of Medicine Martin, Comenius University Bratislava
I.6 - Address of the workplace
Kollarova 2, 036 59 Martin, Slovakia
I.7 - Position
lecturer
I.8 - E-mail address
milangrofik@gmail.com
I.9 - Hyperlink to the entry of a person in the Register of university staff
https://www.portalvs.sk/regzam/detail/30848
I.10 - Name of the study field in which a person works at the university
Neurology
I.11 - ORCID iD
0000-0003-0464-0497

II. - Higher education and further qualification growth

II.1 - First degree of higher education
II.2 - Second degree of higher education
II.a - Name of the university or institution
Jessenius Faculty of Medicine Martin, Comenius University Bratislava
II.b - Year
1997
II.c - Study field and programme
General Medicine
II.3 - Third degree of higher education
II.a - Name of the university or institution
Jessenius Faculty of Medicine Martin, Comenius University Bratislava
II.b - Year
2018
II.c - Study field and programme
Neurology
II.4 - Associate professor
II.a - Name of the university or institution
Jessenius Faculty of Medicine Martin, Comenius University Bratislava
II.b - Year
2023
II.c - Study field and programme
Neurology
II.5 - Professor
II.6 - Doctor of Science (DrSc.)

III. - Current and previous employment

III.a - Occupation-position III.b - Institution III.c - Duration
resident physician Clinic of Neurology, University Hospital Martin 1997-2001
licensed neurologist Clinic of Neurology, University Hospital Martin 2001-present
lecturer Clinic of Neurology, Jessenius Faculty of Medicine Martin 2018-present
neurologist National Institution of Endocrinology and Diabetology 2021-present

IV. - Development of pedagogical, professional, language, digital and other skills

IV.a - Activity description, course name, other IV.b - Name of the institution IV.c - Year
Specialty training in Neurology Slovac Medical University Bratislava, Slovakia 2001
Specialty course in movement disorders Clinic of Neurology, Charles University, General Faculty Hospital Praque, Czech Republic 2012

V. - Overview of activities within the teaching career at the university

V.1 - Overview of the profile courses taught in the current academic year according to study programmes
V.1.a - Name of the profile course V.1.b - Study programme V.1.c - Degree V.1.d - Field of study
Neurology General Medicine II General Medicine
V.2 - Overview of the responsibility for the delivery, development and quality assurance of the study programme or its part at the university in the current academic year
V.3 - Overview of the responsibility for the development and quality of the field of habilitation procedure and inaugural procedure in the current academic year
V.4 - Overview of supervised final theses
V.4.1 - Number of currently supervised theses
V.4.a - Bachelor's (first degree)
0
V.4.b - Diploma (second degree)
5
V.4.c - Dissertation (third degree)
0
V.4.2 - Number of defended theses
V.4.a - Bachelor's (first degree)
0
V.4.b - Diploma (second degree)
1
V.4.c - Dissertation (third degree)
0
V.5 - Overview of other courses taught in the current academic year according to study programmes

VI. - Overview of the research/artistic/other outputs

VI.1 - Overview of the research/artistic/other outputs and the corresponding citations
VI.1.1 - Number of the research/artistic/other outputs
VI.1.a - Overall
120
VI.1.b - Over the last six years
90
VI.1.2 - Number of the research/artistic/other outputs registered in the Web of Science or Scopus databases
VI.1.a - Overall
20
VI.1.b - Over the last six years
10
VI.1.3 - Number of citations corresponding to the research/artistic/other outputs
VI.1.a - Overall
210
VI.1.b - Over the last six years
118
VI.1.4 - Number of citations registered in the Web of Science or Scopus databases
VI.1.a - Overall
173
VI.1.b - Over the last six years
98
VI.1.5 - Number of invited lectures at the international, national level
VI.1.a - Overall
6
VI.1.b - Over the last six years
6
VI.2 - The most significant research/artistic/other outputs
1

Skorvanek M, Rizig M, Athanasiou-Fragkouli A, Necpal J, Straka I, Tamas G, Kurca E, Mosejova A, Han V, Lorincova T, Ostrozovicova M, Liesenerova S, Levicka P, Fajcikova L, Minar M, Valkovic P, Mákos O, Kelemen A, Grofik M, Cibulka M, Jama F, Houlden H; members of the CEGEMOD study group. LRRK2 mutations in Parkinson's disease patients from Central Europe: A case control study. Parkinsonism Relat Disord. 2021 Feb;83:110-112. doi: 10.1016/j.parkreldis.2020.12.021. Epub 2021 Jan 11. PMID: 33561776.

2

Cibulka M, Brodnanova M, Grendar M, Grofik M, Kurca E, Pilchova I, Osina O, Tatarkova Z, Dob-rota D, Kolisek M. SNPs rs11240569, rs708727, and rs823156 in SLC41A1 Do Not Discriminate Between Slovak Patients with Idiopathic Parkinson's Disease and Healthy Controls: Statistics and Machine-Learning Evidence. Int J Mol Sci. 2019 Sep 21;20(19):4688. doi: 10.3390/ijms20194688. PMID: 31546642; PMCID: PMC6801379.

3

Grofik M, Sivák Š, Nosáľ V, Turčanová Koprušáková M, Michalik J, Čierny D, Tatarková Z, Kurča E. The influence of levodopa, entacapone and homocysteine on prevalence of polyneuropathy in patients with Parkinson's disease. J Neurol Sci. 2018 Sep 15;392:28-31. doi: 10.1016/j.jns.2018.06.012. Epub 2018 Jun 20. PMID: 30097148.

4

Straka I, Minár M, Škorvánek M, Grofik M, Danterová K, Benetin J, Kurča E, Gažová A, Boleková V, Wyman-Chick KA, Kyselovič J, Valkovič P. Adherence to Pharmacotherapy in Patients With Par-kinson's Disease Taking Three and More Daily Doses of Medication. Front Neurol. 2019 Jul 31;10:799. doi: 10.3389/fneur.2019.00799. PMID: 31417484; PMCID: PMC6684743.

5

Cibulka M, Brodnanova M, Grendar M, Necpal J, Benetin J, Han V, Kurca E, Nosal V, Skorvanek M, Vesely B, Stanclova A, Lasabova Z, Pös Z, Szemes T, Stuchlik S, Grofik M, Kolisek M. Alzheimer's Disease-Associated SNP rs708727 in SLC41A1 May Increase Risk for Parkinson's Disease: Report from Enlarged Slovak Study. Int J Mol Sci. 2022 Jan 29;23(3):1604. doi: 10.3390/ijms23031604. PMID: 35163527; PMCID: PMC8835868.

VI.3 - The most significant research/artistic/other outputs over the last six years
1

Skorvanek M, Rizig M, Athanasiou-Fragkouli A, Necpal J, Straka I, Tamas G, Kurca E, Mosejova A, Han V, Lorincova T, Ostrozovicova M, Liesenerova S, Levicka P, Fajcikova L, Minar M, Valkovic P, Mákos O, Kelemen A, Grofik M, Cibulka M, Jama F, Houlden H; members of the CEGEMOD study group. LRRK2 mutations in Parkinson's disease patients from Central Europe: A case control study. Parkinsonism Relat Disord. 2021 Feb;83:110-112. doi: 10.1016/j.parkreldis.2020.12.021. Epub 2021 Jan 11. PMID: 33561776.

2

Cibulka M, Brodnanova M, Grendar M, Grofik M, Kurca E, Pilchova I, Osina O, Tatarkova Z, Dob-rota D, Kolisek M. SNPs rs11240569, rs708727, and rs823156 in SLC41A1 Do Not Discriminate Between Slovak Patients with Idiopathic Parkinson's Disease and Healthy Controls: Statistics and Machine-Learning Evidence. Int J Mol Sci. 2019 Sep 21;20(19):4688. doi: 10.3390/ijms20194688. PMID: 31546642; PMCID: PMC6801379.

3

Grofik M, Sivák Š, Nosáľ V, Turčanová Koprušáková M, Michalik J, Čierny D, Tatarková Z, Kurča E. The influence of levodopa, entacapone and homocysteine on prevalence of polyneuropathy in patients with Parkinson's disease. J Neurol Sci. 2018 Sep 15;392:28-31. doi: 10.1016/j.jns.2018.06.012. Epub 2018 Jun 20. PMID: 30097148.

4

Straka I, Minár M, Škorvánek M, Grofik M, Danterová K, Benetin J, Kurča E, Gažová A, Boleková V, Wyman-Chick KA, Kyselovič J, Valkovič P. Adherence to Pharmacotherapy in Patients With Par-kinson's Disease Taking Three and More Daily Doses of Medication. Front Neurol. 2019 Jul 31;10:799. doi: 10.3389/fneur.2019.00799. PMID: 31417484; PMCID: PMC6684743.

5

Cibulka M, Brodnanova M, Grendar M, Necpal J, Benetin J, Han V, Kurca E, Nosal V, Skorvanek M, Vesely B, Stanclova A, Lasabova Z, Pös Z, Szemes T, Stuchlik S, Grofik M, Kolisek M. Alzheimer's Disease-Associated SNP rs708727 in SLC41A1 May Increase Risk for Parkinson's Disease: Report from Enlarged Slovak Study. Int J Mol Sci. 2022 Jan 29;23(3):1604. doi: 10.3390/ijms23031604. PMID: 35163527; PMCID: PMC8835868.

VI.4 - The most significant citations corresponding to the research/artistic/other outputs
1

Skorvanek M, Martinez-Martin P, Kovacs N, Rodriguez-Violante M, Corvol JC, Taba P, Seppi K, Levin O, Schrag A, Foltynie T, Alvarez-Sanchez M, Arakaki T, Aschermann Z, Aviles-Olmos I, Benchetrit E, Benoit C, Bergareche-Yarza A, Cervantes-Arriaga A, Chade A, Cormier F, Datieva V, Gallagher DA, Garretto N, Gdovinova Z, Gershanik O, Grofik M, Han V, Huang J, Kadastik-Eerme L, Kurtis MM, Mangone G, Martinez-Castrillo JC, Mendoza-Rodriguez A, Minar M, Moore HP, Muldmaa M, Mueller C, Pinter B, Poewe W, Rallmann K, Reiter E, Rodriguez-Blazquez C, Singer C, Tilley BC, Valkovic P, Goetz CG, Stebbins GT. Differences in MDS-UPDRS Scores Based on Hoehn and Yahr Stage and Disease Duration. Mov Disord Clin Pract. 2017 Mar 11;4(4):536-544. doi: 10.1002/mdc3.12476. PMID: 30363418; PMCID: PMC6174385.

2

Skorvanek M, Martinez-Martin P, Kovacs N, Zezula I, Rodriguez-Violante M, Corvol JC, Taba P, Seppi K, Levin O, Schrag A, Aviles-Olmos I, Alvarez-Sanchez M, Arakaki T, Aschermann Z, Ben-chetrit E, Benoit C, Bergareche-Yarza A, Cervantes-Arriaga A, Chade A, Cormier F, Datieva V, Gallagher DA, Garretto N, Gdovinova Z, Gershanik O, Grofik M, Han V, Kadastik-Eerme L, Kurtis MM, Mangone G, Martinez-Castrillo JC, Mendoza-Rodriguez A, Minar M, Moore HP, Muldmaa M, Mueller C, Pinter B, Poewe W, Rallmann K, Reiter E, Rodriguez-Blazquez C, Singer C, Valkovic P, Goetz CG, Stebbins GT. Relationship between the MDS-UPDRS and Quality of Life: A large multi-center study of 3206 patients. Parkinsonism Relat Disord. 2018 Jul;52:83-89. doi: 10.1016/j.parkreldis.2018.03.027. Epub 2018 Mar 28. PMID: 29625875.

3

Skorvanek M, Martinez-Martin P, Kovacs N, Rodriguez-Violante M, Corvol JC, Taba P, Seppi K, Levin O, Schrag A, Foltynie T, Alvarez-Sanchez M, Arakaki T, Aschermann Z, Aviles-Olmos I, Benchetrit E, Benoit C, Bergareche-Yarza A, Cervantes-Arriaga A, Chade A, Cormier F, Datieva V, Gallagher DA, Garretto N, Gdovinova Z, Gershanik O, Grofik M, Han V, Huang J, Kadastik-Eerme L, Kurtis MM, Mangone G, Martinez-Castrillo JC, Mendoza-Rodriguez A, Minar M, Moore HP, Muldmaa M, Mueller C, Pinter B, Poewe W, Rallmann K, Reiter E, Rodriguez-Blazquez C, Singer C, Tilley BC, Valkovic P, Goetz CG, Stebbins GT. Differences in MDS-UPDRS Scores Based on Hoehn and Yahr Stage and Disease Duration. Mov Disord Clin Pract. 2017 Mar 11;4(4):536-544. doi: 10.1002/mdc3.12476. PMID: 30363418; PMCID: PMC6174385.

4

Skorvanek M, Rosenberger J, Minar M, Grofik M, Han V, Groothoff JW, Valkovic P, Gdovinova Z, van Dijk JP. Relationship between the non-motor items of the MDS-UPDRS and Quality of Life in patients with Parkinson's disease. J Neurol Sci. 2015;353(1-2):87-91. doi: 10.1016/j.jns.2015.04.013. Epub 2015 Apr 17. PMID: 25918077.

5

Skorvanek M, Minar M, Grofik M, Kracunova K, Han V, Cibulcik F, Necpal J, Gurcik L, Valkovic P. Validation of the Official Slovak Version of the Unified Dyskinesia Rating Scale (UDysRS). Parkinsons Dis. 2015;2015:674796. doi: 10.1155/2015/674796. Epub 2015 Jul 2. PMID: 26229708; PMCID: PMC4503547.

VI.5 - Participation in conducting (leading) the most important research projects or art projects over the last six years
1

APVV-19-0222, „Determination of mitochondrial fitness in diagnostics and prediction of Parkinson´s disease. “ (PI, M. Kolisek, Laboratory of Proteomics and Mitochondriopathies, BioMed JFMED CU).

2

-VEGA 1/0554/19 The role of he STAT3 signalling pathway in the regulation of Na/Mg promoter of the SLC41A1 exchanger: from inflammation to Parkinson disease (PI: M Kolísek, BioMed JFMED CU)

3

-APVV-22-0122 Advanced diagnostics of neurodegenerative disorders using magnetic resonance techniques and atreficial intelligence (PI: Štrbák, biomed Martin)

4
09103-03-V03-00007 –Promoting reserch excellence in underrepresented population and early identifikation of Movement disorders (PI: Škorvánek, UPJŠ Košice)

VII. - Overview of organizational experience related to higher education and research/artistic/other activities

VII.a - Activity, position VII.b - Name of the institution, board VII.c - Duration
member CEGEMOD study groupe - Central European Group on Genetics of Movement Disorders 2019-present
member Movement diśorders society 2020-present
member Slovak neurological society 200-present

VIII. - Overview of international mobilities and visits oriented on education and research/artistic/other activities in the given field of study

IX. - Other relevant facts

IX.a - If relevant, other activities related to higher education or research/artistic/other activities are mentioned

Member of Editorial board of Journal Current Clinical Practice

Vice president of the Section Movement disorders (Slovak Neurological Society)