I. - Basic information

I.1 - Surname

Adamkov

I.2 - Name

Marian

I.3 - Degrees

Prof. MD. DSc.

I.4 - Year of birth

1954

I.5 - Name of the workplace

Department of Histology and Embryology

I.6 - Address of the workplace

JFM UK, Malá Hora 4, 036 01 Martin, Slovakia

I.7 - Position

Head of Department

I.8 - E-mail address

adamkov1@uniba.sk

I.9 - Hyperlink to the entry of a person in the Register of university staff

https://www.portalvs.sk/regzam/detail/3684

I.10 - Name of the study field in which a person works at the university

General Medicine, Dentistry, Midwifery, Nursing, Public Health

II. - Higher education and further qualification growth

II.1 - First degree of higher education

II.2 - Second degree of higher education

II.a - Name of the university or institution

MF CU in Martin

II.b - Year

1979

II.c - Study field and programme

General Medicine

II.3 - Third degree of higher education

II.a - Name of the university or institution

MF CU in Bratislava

II.b - Year

1991

II.c - Study field and programme

Pathological Anatomy and Forensic Medicine

II.4 - Associate professor

II.a - Name of the university or institution

MF PU, Olomouc, Czech Republic

II.b - Year

1995

II.c - Study field and programme

Pathological Anatomy and Forensic Medicine

II.5 - Professor

II.a - Name of the university or institution

CU in Bratislava, JFM in Martin

II.b - Year

2013

II.c - Study field and programme

Pathological Anatomy and Forensic Medicine

II.6 - Doctor of Science (DrSc.)

II.a - Name of the university or institution

St. Elizabeth University of Health and Social sciences

II.b - Year

2019

II.c - Study field and programme

Anatomy, Histology and Embryology

III. - Current and previous employment

III.a - Occupation-position	III.b - Institution	III.c - Duration
Doctor, Department of Pathology	Faculty Hospital Martin	1979 - 1986
Assistent Professor, Associate Professor, Department of Pathology	JFM CU in Martin	1986 - 2003
Senior Consultant	Ministry of Education, Youth and Sports, Oman	2004 - 2005
Professor, Department of Histology and Embryology	JFM CU in Martin	2006 - present

IV. - Development of pedagogical, professional, language, digital and other skills

IV.a - Activity description, course name, other	IV.b - Name of the institution	IV.c - Year
Biopsy of Bone Marrow and Lymph Nodes	Medical Faculty Hannover, Germany	1992
Malignant and Non-malignant Diseases of Bone Marrow and Lymph Nodes	European School of Pathology, Torino, Italy	1994
Malignant and Non-malignant Diseases of Oral Cavity	European School of Pathology, Torino, Italy	1995
Molecular Biology of Malignant Lymphomas	Institute of Medical Science, University of Tokyo, Japan	1997
Molecular Diagnosis of Leukemias	Department of Molecular Hematology, Charles University, Pargue, Czech Republic	1999

V. - Overview of activities within the teaching career at the university

V.1 - Overview of the profile courses taught in the current academic year according to study programmes

V.1.a - Name of the profile course	V.1.b - Study programme	V.1.c - Degree	V.1.d - Field of study
Histology and Embryology 1	General Medicine	I.+II.	General Medicine
Histology and Embryology 2	General Medicine	I.+II.	General Medicine
Histology and Embryology for Dentistry 1	Dentistry, Dental Medicine	I.+II.	Dentistry, Dental Medicine
Histology and Embryology for Dentistry 2	Dentistry, Dental Medicine	I.+II.	Dentistry, Dental Medicine
Anatomy, Histology and Embryology 1	Anatomy, Histology and Embryology	III.	General Medicine
Anatomy, Histology and Embryology 2	Anatomy, Histology and Embryology	III.	General Medicine
Histology	Nursing	I.	Nursing
Histology	Public Health	I.	Public Health
Embryology	Midwifery	I.	Midwifery

V.2 - Overview of the responsibility for the delivery, development and quality assurance of the study programme or its part at the university in the current academic year

V.3 - Overview of the responsibility for the development and quality of the field of habilitation procedure and inaugural procedure in the current academic year

V.4 - Overview of supervised final theses

V.4.1 - Number of currently supervised theses

V.4.b - Diploma (second degree)

V.4.c - Dissertation (third degree)

V.4.2 - Number of defended theses

V.4.b - Diploma (second degree)

V.4.c - Dissertation (third degree)

V.5 - Overview of other courses taught in the current academic year according to study programmes

VI. - Overview of the research/artistic/other outputs

VI.1 - Overview of the research/artistic/other outputs and the corresponding citations

VI.1.1 - Number of the research/artistic/other outputs

VI.1.a - Overall

722

VI.1.b - Over the last six years

151

VI.1.2 - Number of the research/artistic/other outputs registered in the Web of Science or Scopus databases

VI.1.a - Overall

119

VI.1.b - Over the last six years

VI.1.3 - Number of citations corresponding to the research/artistic/other outputs

VI.1.a - Overall

1774

VI.1.b - Over the last six years

351

VI.1.4 - Number of citations registered in the Web of Science or Scopus databases

VI.1.a - Overall

1623

VI.1.b - Over the last six years

345

VI.1.5 - Number of invited lectures at the international, national level

VI.1.a - Overall

VI.1.b - Over the last six years

VI.2 - The most significant research/artistic/other outputs

Neuwirtová, R. - Môciková, K. - Musilová, J. - Jelínek, J. - Havlíček, F. - Michalová, K. - Adamkov, M.: Mixed myelodysplastic and myeloproliferative syndromes In: Leukemia Research. - 20, 9 (1996), 717-726.

Adamkov, M. - Furjelová, M. - Horáček, J. - Benčat, M. - Kružliak, P.: Relationship of mismatch repair proteins and survivin in colon polyps and carcinomas In: Acta Histochemica. - 116, 6 (2014), 1007-1014.

Adamkov, M. - Výbohová, D. - Cígerová, V. - Chyliková, J. - Horáček, J. - Benčat, M.: Expression and significance of survivin in colorectal high grade and low grade adenomas In: Acta Histochemica. - 117, 6 (2015), 590-594.

Adamkov, M. - Halašová, E. - Kajo, K. - Macháleková, K. - Výbohová, D. - Varga, I. - Rajčáni, J.: Survivin: a promising biomarker in breast carcinoma In: Neoplasma. - 57, 6 (2010), 572-577.

Adamkov, M. - Kajo, K. - Výbohová, D. - Krajčovič, J. - Štuller, F. - Rajčáni, J.: Correlations of survivin expression with clinicomorphological parameters and hormonal receptor status in breast ductal carcinoma In: Neoplasma. - 59, 1 (2012), 30-37.

VI.3 - The most significant research/artistic/other outputs over the last six years

Hurta Csizmár, S. – Výbohová, D. - Mešt’anová, V. – Krajňáková, B. – Kajo, K. - Kunertová, L. – Adamkov, M.: Original paper Expression of fascin in association with p16 and Ki-67 in cervical lesions: immunohistochemical study In: Polish Journal of Pathology. – 73, 3 (2022), 208-214.

Mazurakova, A. - Koklesova, L. - Samec, M. - Kudela, E. - Kajo, K. - Skuciova, V. - Csizmár, S.H. - Mestanova, V. - Pec, M. - Adamkov, M. - Al-Ishaq, R.K. - Smejkal, K. - Giordano, F.A. - Büsselberg, D. - Biringer, K. - Golubnitschaja, O. - Kubatka, P.: Anti-breast cancer effects of phytochemicals: primary, secondary, and tertiary care In: EPMA Journal. -13, 2 (2022), 315 – 334.

Kubatka, P. - Uramová, S. - Kello, M. - Kajo, K. - Samec, M. - Jašek, K. - Výbohová, D. - Mazuráková, A. - Mojžiš, J. - Adamkov, M. - Žúbor, P. - Šmejkal, K. - Švajdlenka, E. - Solár, P. - Samson, S. M. - Zulli, A. - Kassayová, M. - Lasabová, Z. - Kwon, T. K. - Péč, M. - Danko, J. - Büsselberg, D.: Anticancer Activities of Thymus vulgaris L. in Experimental Breast Carcinoma In Vivo and In Vitro In: International journal of molecular sciences - 20, 7 (2019), 1-29.

Plavá, J. - Cihová, M. - Buríková, M. - Boháč, M. - Adamkov, M. - Drahošová, S. - Rusnáková, D. - Pinďák, D. - Karaba, M. - Šimo, J. - Mego, M. - Danišovič, Ľ. - Kučerová, L. - Miklíková, S.: Permanent pro-tumorigenic shift in adipose tissue-derived mesenchymal stromal cells induced by breast malignancy In: Cells 9, 2 (2020), 1-19.

Kubatka, P. - Kello, M. - Kajo, K. - Samec, M. - Jašek, K. - Výbohová, D. - Uramová, S. - Mazuráková, A. - Sadloňová, V. - Koklesová, L. - Murín, R. - Adamkov, M. - Šmejkal, K. - Švajdlenka, E. - Solár, P. - Samsom, S. M. - Kassayová, M. - Kwon, T. K. - Žúbor, P. - Péč, M. - Danko, J. - Büsselberg, D. - Mojžiš, J.: Chemopreventive and Therapeutic Efficacy of Cinnamomum zeylanicum L. Bark in Experimental Breast Carcinoma: Mechanistic In Vivo and In Vitro Analyses In: Molecules - 25, 6 (2020), 1-32.

VI.4 - The most significant citations corresponding to the research/artistic/other outputs

MacLennan, K. A. - Bennett, M. H. - Hudson, B. V. - Hudson, S. V.: Diagnosis and grading of nodular sclerosing Hodgkins-disease - a study of 2190 patients. In: International Review of Experimental Pathology, 33, 1992, 27-51.

Adamkov, M. - Plank, L.: Prognostically relevant histopathological subtyping of nodular-sclerotic Hodgkin's disease In: Bratislava medical journal. - 91, 6 (1990), 433-436.

von Wasielewski, S. - Franklin, J. - Fischer, R. - Hubner, K. - Hansmann, M. L. - Diehl, V. - Georgii, A. - von Wasielewski, R.: Nodular sclerosing Hodgkin disease: new grading predicts prognosis in intermediate and advanced stages. In: Blood, 101, 10, 2003, 4063-4069.

Adamkov, M. - Plank, L.: Prognostically relevant histopathological subtyping of nodular-sclerotic Hodgkin's disease In: Bratislava medical journal. - 91, 6 (1990), 433-436.

Mckenzie, J. A. - Grossman, D.: Role of the apoptotic and mitotic ... In: Anticancer Research, 32, 2, 2012, 397-404.

Adamkov, M. - Lauko, Ľ. - Bálentová, S. - Péč, J.) - Péč, M. - Rajčáni, J.: Expression pattern of anti-apoptotic protein survivin in dysplastic nevi In: Neoplasma. - 56, 2 (2009), 130-135.

Kengelbach-Weigand, A. - Tasbihi, K. - Strissel, P. L. - Schmid, R. - Marques, J. M. - Beier, J. P. - Beckmann, M. W. - Strick, R. - Horch, R. E. - Boos, A. M.: Plasticity of patient-matched normal mammary epithelial cells is dependent on autologous adipose-derived stem cells. In: Sciientific Report 2019, 9, 10722.

Bernardo, P. S. - Lemos, L. G. T. - de Moraes, G. N. - Maia, R. C.: Unraveling survivin expression in chronic myeloid leukemia: Molecular interactions and clinical implications. In: Blood Reviews 2020, 43, 100671.

Adamkov, M. - Drahošová, S. - Chytílková, J. - Výbohová, D.: Survivin in breast lesions: Immunohistochemical analysis of 196 cases In: Polish Journal of Pathology. - 68, 4 (2017), 97-305.

VI.5 - Participation in conducting (leading) the most important research projects or art projects over the last six years

VEGA 1/0229/15: Study of the association of induced hyperhomocysteinemia with the progression of neurodegenerative changes under experimental conditions.

Despite of intensive research, whether in clinical or experimental medicine, it is not entirely clear whether hHcy can be considered a risk factor for AD. A better understanding of the nature of the mechanisms involved in stroke in association with hHcy could in the future help to streamline postoperative therapy in connection with neurodegenerative changes in the brain as well as the development of AD-type dementia.

Researcher

VEGA 1/0129/16: Mismatch repair proteins and survivin in pathogenesis of colorectal cancer.

One of the important genetic pathways in the development of CRC is a deficient DNA repair system (mismatch repairing system MMR). CRC is associated with the loss of function of one or more MMRPs. Survivin is a multifunctional protein that inhibits apoptosis, participates in cell cycle regulation and potentiates angiogenesis. MMRP and survivin are considered to be important prognostic parameters and a regulatory mechanism of apoptosis. The aim of the presented project is to determine the relationship between MMRP and survivin in spontaneous CRC.

Responsible Researcher

VEGA 1/0171/18: Influence of induced hyperhomocysteinemia on progression of neuropathological changes with Alzheimer-like features in the experimental model.

The clinical significance of hHcy in the development of stroke and in the prediction of mortality and the development of neurodegeneration has been demonstrated in many studies. In spite of mentioned above, the exact role of hHcy as a independent risk factor for AD is not clear. Elucidation of those mechanisms in ischemic brain a as well as in other key organs could in the future contribute to the streamlining of therapy resp. prevention in patients after ischemic stroke in connection with a disorder of essential amino acid metabolism (as for e.g. hHcy) as well as in the development of cerebrovascular dementia or AD-type dementia.

Researcher

VII. - Overview of organizational experience related to higher education and research/artistic/other activities

VII.a - Activity, position	VII.b - Name of the institution, board	VII.c - Duration
Member of Executive Board and Scientific Secretary	Slovak Medical Society	2018 - 2021
Counsil of Delegates and Member of Executive Board	European Federation for Experimental Morphology (EFEM)	2019 - 2023
Secretary	European Federation for Experimental Morphology (EFEM)	2019 - 2021
Treasurer	European Federation for Experimental Morphology (EFEM)	2021 - 2022
Secretary	European Federation for Experimental Morphology (EFEM)	2022 - 2023
Editorial Board Member	Revista Argentina de Anatomia Clinica	2017 - present
Editorial Board Member	Insights in Breast Cancer	2018 - present
Editorial Board Member	Anatomy, International Journal of Experimental and Clinical Anatomy	2017 - present

VIII. - Overview of international mobilities and visits oriented on education and research/artistic/other activities in the given field of study

IX. - Other relevant facts

Date of last update

2025-02-26

Name and surname:	prof. MUDr. Marian Adamkov, DrSc.
Document type:	Research/art/teacher profile of a person
The name of the university:	Comenius University Bratislava
The seat of the university:	Šafárikovo námestie 6, 818 06 Bratislava