Research/art/teacher profile of a person
Name and surname:
doc. Mgr. Peter Vavrinec, PhD.
Document type:
Research/art/teacher profile of a person
The name of the university:
Comenius University Bratislava
The seat of the university:
Šafárikovo námestie 6, 818 06 Bratislava

I. - Basic information

I.1 - Surname
Vavrinec
I.2 - Name
Peter
I.3 - Degrees
doc. Mgr., PhD.
I.4 - Year of birth
1978
I.5 - Name of the workplace
Faculty of Pharmacy, Comenius University in Bratislava
I.6 - Address of the workplace
Odbojarov 10, 83232, Bratislava
I.7 - Position
docent - Associate profesor
I.8 - E-mail address
peter.vavrinec@uniba.sk
I.9 - Hyperlink to the entry of a person in the Register of university staff
https://www.portalvs.sk/regzam/detail/19202
I.10 - Name of the study field in which a person works at the university
Pharmacy
I.11 - ORCID iD
0000-0002-0484-795X

II. - Higher education and further qualification growth

II.1 - First degree of higher education
II.2 - Second degree of higher education
II.a - Name of the university or institution
Faculty of Pharmacy, Comenius University in Bratislava
II.b - Year
2007
II.c - Study field and programme
Pharmacy
II.3 - Third degree of higher education
II.a - Name of the university or institution
University of Gronoingen, The Nederland
II.b - Year
2012
II.c - Study field and programme
Phramacology
II.4 - Associate professor
II.a - Name of the university or institution
Faculty of Pharmacy, Comenius University in Bratislava
II.b - Year
2022
II.c - Study field and programme
Pharmacology
II.5 - Professor
II.6 - Doctor of Science (DrSc.)

III. - Current and previous employment

III.a - Occupation-position III.b - Institution III.c - Duration
Assistant professor Depertment of Pharmacology and Toxicology, Faculty of Pharmacy, Comenius University in Bratislava 2012-now
Associate professor Depertment of Pharmacology and Toxicology, Faculty of Pharmacy, Comenius University in Bratislava

IV. - Development of pedagogical, professional, language, digital and other skills

IV.a - Activity description, course name, other IV.b - Name of the institution IV.c - Year
Course for GMO projects leadership Ministry of enviroment, SR 2015
Course " Protection of animals used in laboratory science" State veterinary office, SR 2017
Microsurgery techniques University Medical Center of Groningen, The Netherlands 2010
Microbiological safety University Medical Center of Groningen, The Netherlands 2011
FELASA Severity Workshop - Klasifikácia závažnosti postupov v experimentálnych projektoch FELASA 2026

V. - Overview of activities within the teaching career at the university

V.1 - Overview of the profile courses taught in the current academic year according to study programmes
V.1.a - Name of the profile course V.1.b - Study programme V.1.c - Degree V.1.d - Field of study
Pharmacology Pharmacy joint first and second degree Pharmacy
Pharmacology and Toxicology Pharmacy joint first and second degree Pharmacy
Toxicology of Xenobiotics Pharmacy joint first and second degree Pharmacy
Clinical Pharmacology and Toxicology Pharmacy joint first and second degree Pharmacy
Veterrinary Pharmacology Pharmacy joint first and second degree Pharmacy
V.2 - Overview of the responsibility for the delivery, development and quality assurance of the study programme or its part at the university in the current academic year
V.3 - Overview of the responsibility for the development and quality of the field of habilitation procedure and inaugural procedure in the current academic year
V.4 - Overview of supervised final theses
V.4.1 - Number of currently supervised theses
V.4.a - Bachelor's (first degree)
0
V.4.b - Diploma (second degree)
3
V.4.c - Dissertation (third degree)
1
V.4.2 - Number of defended theses
V.4.a - Bachelor's (first degree)
0
V.4.b - Diploma (second degree)
21
V.4.c - Dissertation (third degree)
1
V.5 - Overview of other courses taught in the current academic year according to study programmes
V.5.a - Name of the course V.5.b - Study programme V.5.c - Degree V.5.d - Field of study
Pharmacology Pharmacy joint first and second degree Pharmacy
Toxicology of Xenobiotics Pharmacy joint first and second degree Pharmacy
Clinical Pharmacology and Pharmacotherapy Pharmacy joint first and second degree Pharmacy
Veterinary Pharmacology Pharmacy joint first and second degree Pharmacy
first degree Pharmacy

VI. - Overview of the research/artistic/other outputs

VI.1 - Overview of the research/artistic/other outputs and the corresponding citations
VI.1.1 - Number of the research/artistic/other outputs
VI.1.a - Overall
102
VI.1.b - Over the last six years
42
VI.1.2 - Number of the research/artistic/other outputs registered in the Web of Science or Scopus databases
VI.1.a - Overall
24
VI.1.b - Over the last six years
10
VI.1.3 - Number of citations corresponding to the research/artistic/other outputs
VI.1.a - Overall
218
VI.1.b - Over the last six years
49
VI.1.4 - Number of citations registered in the Web of Science or Scopus databases
VI.1.a - Overall
218
VI.1.b - Over the last six years
49
VI.1.5 - Number of invited lectures at the international, national level
VI.1.a - Overall
1
VI.1.b - Over the last six years
1
VI.2 - The most significant research/artistic/other outputs
1

The protective effect of 1-methyltryptophan isomers in renal ischemia-reperfusion injury is not exclusively dependent on indolamine 2,3-dioxygenase inhibition.

Čepcová D, Kema IP, Sandovici M, Deelman LE, Šišková K, Klimas J, Vavrinec P, Vavrincová-Yaghi D.

Biomed Pharmacother. 2021 Mar;135:111180. doi: 10.1016/j.biopha.2020.111180. Epub 2021 Feb 1

2

Princípy klinickej farmácie a farmakoterapie [textový dokument (print)] [učebnica pre vysoké školy] : Vysokoškolská učebnica / Kuželová, Magdaléna; Foltánová; Kosírová, Stanislava; Kiliánová, Zuzana; Kráľová; Ondriašová, Elena; Vavrincová, Diana; Vavrinec, Peter; Cagáňová, Blažena [Recenzent] ; Klimas, Ján [Recenzent] ; Kriška, Milan [Recenzent] ; Laššán, Štefan [Recenzent] ; Sýkora, Juraj [Recenzent]. – 1. vyd. – Bratislava (Slovensko) : Zdravotnícke vydavateľstvo HERBA, 2025. – 368 s. [tlačená forma]. – ISBN 978-80-8229-055-7

3

O6-methylguanine-DNA methyltransferase inhibition leads to cellular senescence and vascular smooth muscle dysfunction

Jakub Krivy, Svetozar Misuth, Marina Puchovska, Sona Sykorova, Diana Vavrincova-Yaghi, Peter Vavrinec

Biomed Pharmacother 2025 Jun:187:118103. doi: 10.1016/j.biopha.2025.118103. Epub 2025 Apr 28.

4

Vildagliptin restores renal myogenic function and attenuates renal sclerosis independently of effects on blood glucose or proteinuria in zucker diabetic fatty rat.

Vavrinec P, Henning RH, Landheer SW, Wang Y, Deelman LE, Dokkum RP, Buikema H.

Curr Vasc Pharmacol. 2014;12(6):836-44. doi: 10.2174/15701611113116660151.

5

Vildagliptin improves vascular smooth muscle relaxation and decreases cellular senescence in the aorta of doxorubicin-treated rats.

Mišúth S, Uhrinová M, Klimas J, Vavrincová-Yaghi D, Vavrinec P.

Vascul Pharmacol. 2021 Jun;138:106855. doi: 10.1016/j.vph.2021.106855. Epub 2021 Mar 17

VI.3 - The most significant research/artistic/other outputs over the last six years
1

The protective effect of 1-methyltryptophan isomers in renal ischemia-reperfusion injury is not exclusively dependent on indolamine 2,3-dioxygenase inhibition.

Čepcová D, Kema IP, Sandovici M, Deelman LE, Šišková K, Klimas J, Vavrinec P, Vavrincová-Yaghi D.

Biomed Pharmacother. 2021 Mar;135:111180. doi: 10.1016/j.biopha.2020.111180. Epub 2021 Feb 1

2

Vildagliptin improves vascular smooth muscle relaxation and decreases cellular senescence in the aorta of doxorubicin-treated rats.

Mišúth S, Uhrinová M, Klimas J, Vavrincová-Yaghi D, Vavrinec P.

Vascul Pharmacol. 2021 Jun;138:106855. doi: 10.1016/j.vph.2021.106855. Epub 2021 Mar 17

3

O6-methylguanine-DNA methyltransferase inhibition leads to cellular senescence and vascular smooth muscle dysfunction

Jakub Krivy, Svetozar Misuth, Marina Puchovska, Sona Sykorova, Diana Vavrincova-Yaghi, Peter Vavrinec

Biomed Pharmacother 2025 Jun:187:118103. doi: 10.1016/j.biopha.2025.118103. Epub 2025 Apr 28.

4

Princípy klinickej farmácie a farmakoterapie [textový dokument (print)] [učebnica pre vysoké školy] : Vysokoškolská učebnica / Kuželová, Magdaléna; Foltánová; Kosírová, Stanislava; Kiliánová, Zuzana; Kráľová; Ondriašová, Elena; Vavrincová, Diana; Vavrinec, Peter; Cagáňová, Blažena [Recenzent] ; Klimas, Ján [Recenzent] ; Kriška, Milan [Recenzent] ; Laššán, Štefan [Recenzent] ; Sýkora, Juraj [Recenzent]. – 1. vyd. – Bratislava (Slovensko) : Zdravotnícke vydavateľstvo HERBA, 2025. – 368 s. [tlačená forma]. – ISBN 978-80-8229-055-7

5

Gaál Kovalčíková A, Janovičová Ľ, Hodosy J, Bábíčková J, Vavrincová-Yaghi D, Vavrinec P, Boor P, Podracká Ľ, Šebeková K, Celec P, Tóthová Ľ. Extracellular DNA concentrations in various aetiologies of acute kidney injury. Sci Rep. 2022 Oct 7;12(1):16812. doi: 10.1038/s41598-022-21248-7. PMID: 36207374; PMCID: PMC9546839.

VI.4 - The most significant citations corresponding to the research/artistic/other outputs
1

Kastritis, E. - Papassotiriou, I. - Merlini, G. - Milani, P. - Terpos, E. - Basset, M. - Akalestos, A. - Russo, F. - Psimenou, E. - Apostolakou, F. - Roussou, M. - Gavriatopoulou, M. - Eleutherakis-Papaiakovou, E. - Fotiou, D. -Ziogas, D.C. - Papadopoulou, E. - Pamboucas, C. - Dimopoulos, M.A. - Palladini, G.: Blood, Vol. 131, No. 14, 2018, s. 1575 

2

Acute kidney injury. Kellum JA, Romagnani P, Ashuntantang G, Ronco C, Zarbock A, Anders HJ.

Nat Rev Dis Primers. 2021 Jul 15;7(1):52. doi: 10.1038/s41572-021-00284-z.

3

Platten, M. - Nollen, E.A.A. - Röhrig, U.F. - Fallarino, F. - Opitz, C.A.: Nature Reviews Drug Discovery, Vol. 18, No. 5, 2019, s. 401 

4

NETs-Induced Thrombosis Impacts on Cardiovascular and Chronic Kidney Disease. Manovriti Thakur, Carolina Victoria Cruz Junho, Sarah Maike Bernhard, Marc Schindewolf, Heidi Noels, Yvonne Döring Circulation Research Review Open Access2023DOI: 10.1161/CIRCRESAHA.123.321750

5

Chronic Treatment With an Erythropoietin Receptor Ligand Prevents Chronic Kidney Disease-Induced Enlargement of Myocardial Infarct Size. Nishizawa K, Yano T, Tanno M, Miki T, Kuno A, Tobisawa T, Ogasawara M, Muratsubaki S, Ohno K, Ishikawa S, Miura T.

Hypertension. 2016 Sep;68(3):697-706. doi: 10.1161/HYPERTENSION AHA.116.07480. Epub 2016 Jul 25.


VI.5 - Participation in conducting (leading) the most important research projects or art projects over the last six years
1

Principal investigator of the grant "The role of DNA repair in cellular senescence in the context of cardiovascular and renal diseases" Grant from the Scientific Grant Agency of the Ministry of Education, Science, Research and Sports(MŠVVaŠ SR a SAV) (VEGA) 1/0121/22

2

Principal investigator of the grant "O6-benzylguanine in fight against fibrosis: innovative attitude" Grant from the Scientific Grant Agency of the Ministry of Education, Science, Research and Sports(MŠVVaŠ SR a SAV) (VEGA) 1/0297/26

3

Scientific co-worker: „Iinterference with indoleamine 2,3-dioxygenase metabolism as a new therapeutic strategy for fibrotic diseases." Grant from Vedecky grant agency of the Ministry of Education, Science, Research and Sports (MŠVVaŠ SR a SAV) 1/0027/20

4

Scientific co-worker. Vavrincová D. APVV-23-0399 IDO - new strategy in therapy of fibrotic diseases.

5

Scientific co-worker. Vavrincová D. Antifibrotic potential in fibrotic diseases. 1/0513/24

VII. - Overview of organizational experience related to higher education and research/artistic/other activities

VII.a - Activity, position VII.b - Name of the institution, board VII.c - Duration
Member of the National Committee for the Protection of Animals used for Scientific Purposes Ministry of Agriculture and Rural Development of the Slovak Republic 2017 - now
Member of the commissions for final state exams and final theses defence in MSc programme Comenius University in Bratislava, Depertment of Pharmacology and Toxicology 2019-now
Supervisor for PhD studies Comenius University in Bratislava, Depertment of Pharmacology and Toxicology 2017-now
Supervisor for MScs theses Comenius University in Bratislava, Depertment of Pharmacology and Toxicology 2013-now
Head of laboratory animals facility Comenius University in Bratislava, Phaculty of Pharmacy 1.9.2023 - now

VIII. - Overview of international mobilities and visits oriented on education and research/artistic/other activities in the given field of study

IX. - Other relevant facts

Date of last update
2025-02-27