Research/art/teacher profile of a person
Name and surname:
doc. RNDr. Miroslava Šupolíková, PhD.
Document type:
Research/art/teacher profile of a person
The name of the university:
Comenius University Bratislava
The seat of the university:
Šafárikovo námestie 6, 818 06 Bratislava

I. - Basic information

I.1 - Surname
Šupolíková
I.2 - Name
Miroslava
I.3 - Degrees
doc. RNDr., PhD.
I.4 - Year of birth
1974
I.5 - Name of the workplace
Comenius University in Bratislava, Faculty of Natural Sciences, Department of Microbiology and Virology; Faculty of Pharmacy, Department of Galenic Pharmacy
I.6 - Address of the workplace
Ilkovičova 6, 842 15 Bratislava 4; Odbojárov 10 832 32 Bratislava 3
I.7 - Position
Associate Professor
I.8 - E-mail address
miroslava.supolikova@uniba.sk
I.9 - Hyperlink to the entry of a person in the Register of university staff
https://www.portalvs.sk/regzam/detail/4438
I.10 - Name of the study field in which a person works at the university
Biology, Pharmacy
I.11 - ORCID iD
https://orcid.org/0000-0003-0793-9072

II. - Higher education and further qualification growth

II.1 - First degree of higher education
II.2 - Second degree of higher education
II.a - Name of the university or institution
Comenius University in Bratislava, Faculty of Natural Sciences
II.b - Year
1997
II.c - Study field and programme
Biology, specialization Virology
II.3 - Third degree of higher education
II.a - Name of the university or institution
Comenius University in Bratislava, Faculty of Natural Sciences
II.b - Year
2001
II.c - Study field and programme
Microbiology
II.4 - Associate professor
II.a - Name of the university or institution
Comenius University in Bratislava, Faculty of Natural Sciences
II.b - Year
2016
II.c - Study field and programme
Virology
II.5 - Professor
II.6 - Doctor of Science (DrSc.)

III. - Current and previous employment

III.a - Occupation-position III.b - Institution III.c - Duration
assistant Comenius University in Bratislava, Faculty of Natural Sciences, Department of Microbiology and Virology 10. 2000 – 05. 2001
special assistant Comenius University in Bratislava, Faculty of Natural Sciences, Department of Microbiology and Virology 06. 2001 – 01. 2017
Associate Professor Comenius University in Bratislava, Faculty of Natural Sciences, Department of Microbiology and Virology 02.2017- lasts

IV. - Development of pedagogical, professional, language, digital and other skills

IV.a - Activity description, course name, other IV.b - Name of the institution IV.c - Year
study stay in the laboratory of Prof. A.A. Nasha University of Edinburgh, Department of Veterinary Pathology 1998
Cambridge English Course (1995-1997) Academy of Education, Bratislava 1997
English language course (1998-2000) State Language School, Bratislava 2000

V. - Overview of activities within the teaching career at the university

V.1 - Overview of the profile courses taught in the current academic year according to study programmes
V.1.a - Name of the profile course V.1.b - Study programme V.1.c - Degree V.1.d - Field of study
Immunology Biology, Medical Biology I. Biology
Microbiology and Virology Biochemistry I. Chemistry
Microbiology and Virology Teacher Training of Biology I. Teacher Training and Education Science
Immunological aspects of host-pathogen interactions Virology, Microbiology, Molecular Biology II. Biology
Pharmaceutical technology 1., 2. Pharmacy II. Pharmacy
V.2 - Overview of the responsibility for the delivery, development and quality assurance of the study programme or its part at the university in the current academic year
V.2.a - Name of the study programme V.2.b - Degree V.2.c - Field of study
Biology, Medical Biology I. Biology
Biochemistry I. Chemistry
Teacher Training of Biology I. Teacher Training and Education Science
Virology, Microbiology, Molecular Biology II. Biology
V.3 - Overview of the responsibility for the development and quality of the field of habilitation procedure and inaugural procedure in the current academic year
V.4 - Overview of supervised final theses
V.4.1 - Number of currently supervised theses
V.4.a - Bachelor's (first degree)
2
V.4.b - Diploma (second degree)
0
V.4.c - Dissertation (third degree)
2
V.4.2 - Number of defended theses
V.5 - Overview of other courses taught in the current academic year according to study programmes
V.5.a - Name of the course V.5.b - Study programme V.5.c - Degree V.5.d - Field of study
Exercise in basic immunology Biology, Medical Biology I. Biology
Exercise in virology Biology, Medical Biology I. Biology
Special seminar 1 Microbiology and virology II. Biology
Seminar for bachelor thesis in virology Biology, Medical Biology I. Biology
Seminar for diploma thesis in virology Microbiology and virology II. Biology

VI. - Overview of the research/artistic/other outputs

VI.1 - Overview of the research/artistic/other outputs and the corresponding citations
VI.1.1 - Number of the research/artistic/other outputs
VI.1.a - Overall
150
VI.1.b - Over the last six years
113
VI.1.2 - Number of the research/artistic/other outputs registered in the Web of Science or Scopus databases
VI.1.a - Overall
36
VI.1.b - Over the last six years
23
VI.1.3 - Number of citations corresponding to the research/artistic/other outputs
VI.1.a - Overall
140
VI.1.b - Over the last six years
53
VI.1.4 - Number of citations registered in the Web of Science or Scopus databases
VI.1.a - Overall
102
VI.1.b - Over the last six years
49
VI.1.5 - Number of invited lectures at the international, national level
VI.1.a - Overall
4
VI.1.b - Over the last six years
4
VI.2 - The most significant research/artistic/other outputs
1

Detection of Murine Herpesvirus 68 (MHV-68) in Dermacentor reticulatus Ticks; https://link.springer.com/article/10.1007/s00248-015-0622-7

2

Murine Gammaherpesvirus (MHV-68) Transforms Cultured Cells in vitro; https://www.karger.com/Article/FullText/370071

3

Cells transformed by murine herpesvirus 68(MHV-68) release compounds with transforming and transformed phenotype suppressing activity resembling growth factors; https://pdfs.semanticscholar.org/560e/4f429b74752eedf092bf30bf0e2ae2a2c393.pdf?_ga=2.29403263.172385128.1603872715-1623526796.1603872715

4

Murine herpesvirus-68-related growth factors treatment correlates with decrease of p53 and HIF-1α protein levels; https://doi.org/10.1093/femspd/ftad004

5

Synergistic Antiproliferative Effects of Chondroitin Sulfate and Fucoidan in Tumor-derived Spheroids;https://www.researchgate.net/publication/388214601

VI.3 - The most significant research/artistic/other outputs over the last six years
1

Murine herpesvirus-68-related growth factors treatment correlates with decrease of p53 and HIF-1α protein levels; https://doi.org/10.1093/femspd/ftad004

2

Functionalization of decavanadate anion by coordination to cobalt(II) : Binding to proteins, cytotoxicity, and water oxidation catalysis; https://pubmed.ncbi.nlm.nih.gov/36423394/

3

Spheroids as 3D Cell Models for Testing of_Drugs; https://www.researchgate.net/publication/373378357

4

Rheological behavior and texture analysis of oleogel suspension containing chondroitin sulfate and fucoidan; https://farmaciajournal.com/issue-articles/rheological-behavior-and-texture-analysis-of-oleogel-suspension-containing-chondroitin-sulfate-and-fucoidan/

5

Normalization of Immune Response via Chondroitin Sulfate and Fucoidan Targeting N-Acetylgalactosaminidase; https://www.mdpi.com/2218-0532/93/4/47

VI.4 - The most significant citations corresponding to the research/artistic/other outputs
1

Detection of Murine Herpesvirus 68 (MHV-68) in Dermacentor reticulatus Ticks.

2023 [01/20] / GBR - Liu, Yuhang - Guo, Lei - Wang, Guoshuai - Gao, Fei - Tu, Zhongzhong - Xu, Deming - Sun, Lanshun - Yi, Le - Zhu, Guoqiang - Tu, Changchun - He, Biao. DNA virome of ticks in the Northeast and Hubei provinces of China reveals diverse single-stranded circular DNA viruses [elektronický dokument]. DOI 10.1186/s13071-023-05684-6 In: Parasites & Vectors. Londýn: Springer Nature. BioMed Central, 2023, Roč. 16, č. 1, art. no. 61 [online]. ISSN (online) 1756-3305. - SCO ; WOS CC, s. art. no. 61

2

Murine Gammaherpesvirus (MHV-68) Transforms Cultured Cells in vitro. 

2024 [01] / USA - Kara, M. Latent Macrophage and Immature B Cell Lines Generated with Hygromycin-Resistant Murine Gammaherpesvirus 68 Genome Expresses Modest Levels of Viral miRNAs [elektronický dokument]. DOI 10.1134/S0026893324010138 In: Molecular biology. [s.l.]: Springer Nature, 2024, Roč. 58, č. 1, s. 123-132 [tlačená forma] [online]. ISSN 0026-8933. ISSN (online) 1608-3245. - SCO ; WOS CC, s. 123 - 132

3

Cells transformed by murine herpesvirus 68(MHV-68) release compounds with transforming and transformed phenotype suppressing activity resembling growth factors.

2018 [01] / GRC - Cimpean, A.M. - Lalošević, D. - Lalošević, V. - Banović, P. - Raica, M. - Alexandru Mederle, O. Článok [elektronický dokument] In: In vivo. Atény: International Institute of Anticancer Research, 2018, Roč. 32, č. 4, [tlačená forma] [online]. ISSN 0258-851X. ISSN (online) 1791-7549. - SCIE ; WOS CC, s. 791 - 798

4

Murine herpesvirus-68-related growth factors treatment correlates with decrease of p53 and HIF-1α protein levels.

5

Synergistic Antiproliferative Effects of Chondroitin Sulfate and Fucoidan in Tumor-derived Spheroids.

2025 [01] / CHE - Condori Macuri, Rosa María - Alzamora-Gonzales, Libertad - Colona-Vallejos, Erasmo Honorio - Cruz Riquelme, Raisa Teresa - Pecho Chávez, Laura Inés - Cisneros Gutierrez, Jherson Oscar - Montejo Anlas, Victor Alonso. Synergistic Anticancer Activity of Fucoidan from Lessonia trabeculata Combined with Chemotherapeutic Agents in 4T1 Breast Spheroids [elektronický dokument]. DOI 10.3390/md23120451 In: Marine drugs. Basel: Multidisciplinary Digital Publishing Institute, 2025, Roč. 23, č. 12, art. no. 451 , s. 1-20 [online]. ISSN (online) 1660-3397. - SCO ; WOS CC, s. 1 - 20

VI.5 - Participation in conducting (leading) the most important research projects or art projects over the last six years
1

VEGA 1/0146/23: Study of drugs based on glycosaminoglycans, sulfated heteropolysaccharides and live bacterial strains with antiproliferative and immunomodulatory properties in vitro and in vivo (01/23 - 12/26), principal investigator of the project.

The aim of the project is to monitor the phagocytic activity of macrophages by increasing the production of GcMAF protein in the body by using drugs prepared on the basis of glycosaminoglycans, sulfated heteropolysaccharides and live bacterial strains. In the research we will study the antiproliferative, antitumor and immunomodulatory effects of these substances. The essence of the immunomodulatory effect of substances based on glycosaminoglycans-low molecular weight chondroitin sulphate and fucoidan-sulphated heteropolysaccharide containing fucose and galactosamine is the in vivo increase of GcMAF protein production by inhibition of nagalase activity. Initially, we will start testing substances on 2D and 3D cell cultures. Following targeted subcutaneous administration of tumor cells to laboratory mice, we will monitor the effect of the oral drug on progression as well as inhibition of xenografts formed. We anticipate that experimental studies will bring medically significant markers to GcMAF immunotherapy.

2

KEGA 008UK-4/2019: Integration of interactive electronic textbooks and e-learning processes in the teaching of immunology and virology (01/19 – 12/21), principal investigator of the project.

The output of the submitted project will be interactive electronic textbooks from virology in English and a manual of methods and procedures from immunology and molecular biology of viruses, as well as teaching texts of basic virological methods in printed form. Interactive electronic textbooks will be introduced in the processes of teaching immunology and virology in integration with e-learning systems.

3

VEGA 1/0061/18: The analysis of bioactive substances associated with Murine herpesvirus with antiproliferative andimmunomodulatory properties in vitro and in vivo (01/18 – 12/21), principal investigator of the project. 

The project represents an original study devoted to the biological and immunological characterization of bioactive compounds associated with the virus MHV-68, which is referred to as MHGF-68 In spite of intensive studies of MHV-68, no attention has been hitherto paid to substances resembling growth factors associated with this virus. We characterize the selected fraction of MHGF-68 with antiproliferative effects in vitro on different cell lines and in vivo in a model of athymic mice. The obtained results suggest the possible application of MHGF-68 in the treatment or prevention of cancer associoated with herpesvirus.

VII. - Overview of organizational experience related to higher education and research/artistic/other activities

VII.a - Activity, position VII.b - Name of the institution, board VII.c - Duration
Membership in the Academic Senate, pedagogical commission, senator Comenius University in Bratislava, Faculty of Natural Sciences 23.5. 2023 - 22.5. 2027
Membership in the Departmental Committee of Virology and Microbiology for dissertation exams Comenius University in Bratislava, Faculty of Natural Sciences 09. 2014 - lasts
Membership in the Biological Section for Pedagogy Comenius University in Bratislava, Faculty of Natural Sciences 02. 2017 - lasts
Membership in the organizing committee of the Student Scientific Conference Comenius University in Bratislava, Faculty of Natural Sciences 2012-2014
Membership in the CSSM Czechoslovak Microbiological Society Czechoslovak Microbiological Society Bratislava-Prague 2014 - lasts
Membership in the Slovak Pharmaceutical Society Slovak Medical Society 02.2021-lasts
Membership in the Association of Pharmacists of Bratislava and Western Slovakia Slovak Medical Society 02.2021-lasts

VIII. - Overview of international mobilities and visits oriented on education and research/artistic/other activities in the given field of study

IX. - Other relevant facts

Date of last update
2026-06-22