I. - Basic information

I.1 - Surname

Nováková

I.2 - Name

Eva

I.3 - Degrees

PhDr.

I.4 - Year of birth

1968

I.5 - Name of the workplace

Comenius University in Bratislava, Faculty of Natural Sciences, Depertment of Microbiology and Virology

I.6 - Address of the workplace

Mlynská dolina, Ilkovičova 6, 84215 Bratislava

I.7 - Position

research worker/Assistent

I.8 - E-mail address

eva.novakova@uniba.sk

I.9 - Hyperlink to the entry of a person in the Register of university staff

https://www.portalvs.sk/regzam/detail/4183

I.10 - Name of the study field in which a person works at the university

Biology, Pharmacy

I.11 - ORCID iD

https://orcid.org/0000-0002-9219-0803

II. - Higher education and further qualification growth

II.1 - First degree of higher education

II.a - Name of the university or institution

St. Elizabeth University of Health and Social Work in Bratislava

II.b - Year

2014

II.2 - Second degree of higher education

II.a - Name of the university or institution

St. Elizabeth University of Health and Social Work in Bratislava

II.b - Year

2016

II.3 - Third degree of higher education

II.4 - Associate professor

II.5 - Professor

II.6 - Doctor of Science (DrSc.)

III. - Current and previous employment

III.a - Occupation-position	III.b - Institution	III.c - Duration
Lecturer/research worker/Assistent	Commenius University in Bratislava, Faculty of Natural Sciences	2016 -up to now

IV. - Development of pedagogical, professional, language, digital and other skills

V. - Overview of activities within the teaching career at the university

V.1 - Overview of the profile courses taught in the current academic year according to study programmes

V.1.a - Name of the profile course	V.1.b - Study programme	V.1.c - Degree	V.1.d - Field of study
Virology	Biology, Medical Biology	I.	Biology
Basic immunology practicals	Biology, Medical Biology	I.	Biology

V.2 - Overview of the responsibility for the delivery, development and quality assurance of the study programme or its part at the university in the current academic year

V.3 - Overview of the responsibility for the development and quality of the field of habilitation procedure and inaugural procedure in the current academic year

V.4 - Overview of supervised final theses

V.4.1 - Number of currently supervised theses

V.4.a - Bachelor's (first degree)

V.4.2 - Number of defended theses

V.4.a - Bachelor's (first degree)

V.5 - Overview of other courses taught in the current academic year according to study programmes

V.5.a - Name of the course	V.5.b - Study programme	V.5.c - Degree	V.5.d - Field of study
Microbiology and virology	Biology teacher training	I.	Teacher Training and Education Science
Microbiology and virology	Biochemistry	I.	Chemistry
Virology	Biology, Medical biology, Systematic biology	I.	Biology
Basic immunology practicals	Biology, Medical biology	I.	Biology
Virology	Biological Chemistry	I.	Biology
Pathogenesis of viral infections and medical virology	Microbiology, Virology	II.	Biology

VI. - Overview of the research/artistic/other outputs

VI.1 - Overview of the research/artistic/other outputs and the corresponding citations

VI.1.1 - Number of the research/artistic/other outputs

VI.1.a - Overall

VI.1.b - Over the last six years

VI.1.2 - Number of the research/artistic/other outputs registered in the Web of Science or Scopus databases

VI.1.a - Overall

VI.1.b - Over the last six years

VI.1.3 - Number of citations corresponding to the research/artistic/other outputs

VI.1.4 - Number of citations registered in the Web of Science or Scopus databases

VI.1.5 - Number of invited lectures at the international, national level

VI.2 - The most significant research/artistic/other outputs

Transformation of Cells by Photoinactivated Murine Gamma-Herpesvirus 68 during Nonproductive and Quiescent Infection; https://www.karger.com/Article/Fulltext/479373

Murine herpesvirus-68-related growth factors treatment correlates with decrease of p53 and HIF-1α protein levels; https://doi.org/10.1093/femspd/ftad004

Šupolíková, Miroslava [UKOPRBMV] (30%) - Labudová, Martina (20%) - Nováková, Eva (20%) - Vojs Staňová, Andrea [UKOPRCAL] (10%) - Šišovský, Vladimír [UKOLFUPA] (10%) - Golais, František [UKOPRBMV] (10%): The Effect of Murine Herpesvirus 68 (MHV-68)Related Growth Factor 68 (MHGF-68) on the Tumor Progression in Athymic Nude Mice

Lit.: 25 zázn.

In: American Journal of Biomedical and Life Sciences. - Roč. 6, č. 6 (2018), s. 127-131. - ISSN (print) 2330-8818

Pagáč Tomáš - Šafař Peter - Marchalin Štefan - Ježíková Zuzana - Balonová Barbora - Šupolíková Miroslava - Nováková Eva - Kubíčková Jana - Šoral Michal - Sivý J. - Olejníková Petra (2018): Asymetric synthesis and study of biological activity of (epi-)benzoanalogues of bioactive phenanthroquinolizidine alkaloids. In Monatshefte fur chemie. DOI: 10.1007/s00706-018-2244-5.

Spheroids as 3D Cell Models for Testing of_Drugs; https://www.researchgate.net/publication/373378357

VI.3 - The most significant research/artistic/other outputs over the last six years

Transformation of Cells by Photoinactivated Murine Gamma-Herpesvirus 68 during Nonproductive and Quiescent Infection; https://www.karger.com/Article/Fulltext/479373

Mrázová Veronika - Kúdelová Marcela - Smolinská Miroslava - Nováková Eva - Šupolíková Miroslava - Vrbová Michaela - Golais František (2017): Transformation of Cells by Photo-inactivated Murine Gamma-Herpesvirus 68 during Nonproductive and Quiescent Infection.

Intervirology 2017, 60: 61-68. DOI: 10.1159/000479373

Lit.: 25 zázn.

In: American Journal of Biomedical and Life Sciences. - Roč. 6, č. 6 (2018), s. 127-131. - ISSN (print) 2330-8818

Spheroids as 3D Cell Models for Testing of_Drugs; https://www.researchgate.net/publication/373378357

VI.4 - The most significant citations corresponding to the research/artistic/other outputs

o1] 2019 - Wiehe, A. - O'brien, J.M. - Senge, M.O. - In: Photochemical and Photobiological Sciences, Vol. 18, No. 11, 2019 ; s. 2565-2612 ; SCI

260/17 IF 2,9

VI.5 - Participation in conducting (leading) the most important research projects or art projects over the last six years

VEGA 1/0061/18 Analýza bioaktívnych látok asociovaných s Myším herpetickým vírusom s antiproliferatívnymi a imunomodulačnými vlastnosťami v podmienkach in vitro a in vivo (01/18 – 12/21), zodpovedná riešiteľka projektu. Projekt predstavuje originálnu štúdiu venovanú biologickej a imunologickej charakterizácii bioaktívnych látok asociovaných s vírusom MHV-68, ktoré sú označované ako MHGF-68. Napriek intenzívnemu štúdiu spomínaného vírusu sa ešte nikto vo svete nevenoval štúdiu látok asociovaných s MHV-68, pripomínajúcich rastové faktory. Charakterizovali sme vybrané frakcie MHGF-68 s antiproliferatívnymi účinkami in vitro na rôznych bunkových líniách a in vivo na modeli laboratórnych nahých myší. Získané výsledky naznačujú predpoklad možnej aplikácie MHGF-68 ako liečiva v prevencii a/alebo liečbe nádorových ochorení asociovaných s herpetickými vírusmi.

VEGA (2016 – 2019)Hantavírusy a prekračovanie druhových bariér. Hantavírusy sú vírusy patriace do rodu Hantavirus, čeľade Bunyaviridae. Šíria sa medzi hlodavcami a môžu nakaziť aj ľudskú populáciu. V súčasnosti je známych niekoľko sérotypov hantavírusov (napr. Hantaan, Tula – Európa, Seoul – geopolitný výskyt, Puumala – Európa, Sibír, Belgrade – Balkán, Prospect Hill, Muerto Canyon – Severná Amerika). Projekt predstavuje originálnu štúdiu venovanú hantavírus a zaoberá sa štúdiom druhových bariér. Účasť na riešení.

KEGA 008UK-4/2019 Integrácia interaktívnych elektronických učebníc a e-learningových procesov vo výučbe imunológie a virológie (01/19 – 12/21), zodpovedná riešiteľka projektu. Výstupom predloženého projektu budú interaktívne elektronické učebnice z virológie v anglickom jazyku a manuál metód a postupov z imunológie a molekulárnej biológie vírusov, ako aj učebné texty základných virologických metód v tlačenej forme. Interaktívne elektronické učebnice budú v integrácii s e-learningovými systémami zavedené do procesov výučby imunológie a virológie.

APVV-16-0518 (2017-2021), O ovciach, kozách a víruse kliešťovej encefalitídy (Of Sheep, Goats and Tick-borne Encephalitis virus).. Vírus kliešťovej encefalitídy sa do mlieka dostáva krvou. Mliekom sa začne vylučovať na druhý až tretí deň po nakazení zvieraťa a v mlieku sa objavuje asi za šesť dní. Projekt predstavuje originálnu štúdiu venovanú problému niektorých salašoch, kde nastalo nakazenie ovčieho a kozieho mlieka. Pridaním kozieho mlieka do ovčieho dochádza k potravinovej epidémií kliešťovej encefalitídy na Slovensku. Účasť na riešení.

1/0146/23: Study of drugs based on glycosaminoglycans, sulfated heteropolysaccharides and live bacterial strains with

antiproliferative and immunomodulatory properties in vitro and in vivo.

The aim of the project is to monitor the phagocytic activity of macrophages by increasing the production of

GcMAF protein in the body by using drugs prepared on the basis of glycosaminoglycans, sulfated

heteropolysaccharides and live bacterial strains. In the research we will study the antiproliferative, antitumor and

immunomodulatory effects of these substances. The essence of the immunomodulatory effect of substances

based on glycosaminoglycans-low molecular weight chondroitin sulphate and fucoidan-sulphated

heteropolysaccharide containing fucose and galactosamine is the in vivo increase of GcMAF protein production

by inhibition of nagalase activity. Initially, we will start testing substances on 2D and 3D cell cultures. Following

targeted subcutaneous administration of tumor cells to laboratory mice, we will monitor the effect of the oral drug

on progression as well as inhibition of xenografts formed. We anticipate that experimental studies will bring

medically significant markers to GcMAF immunotherapy.

VII. - Overview of organizational experience related to higher education and research/artistic/other activities

VII.a - Activity, position	VII.b - Name of the institution, board	VII.c - Duration
Membership in the CSSM Czechoslovak Microbiological Society	Czechoslovak Microbiological Society Bratislava-Prague	2020 - lasts

VIII. - Overview of international mobilities and visits oriented on education and research/artistic/other activities in the given field of study

IX. - Other relevant facts

Date of last update

2023-09-20

Name and surname:	PhDr. Eva Nováková
Document type:	Research/art/teacher profile of a person
The name of the university:	Comenius University Bratislava
The seat of the university:	Šafárikovo námestie 6, 818 06 Bratislava