Research/art/teacher profile of a person
Name and surname:
PharmDr. Dalibor Nakládal, PhD.
Document type:
Research/art/teacher profile of a person
The name of the university:
Comenius University Bratislava
The seat of the university:
Šafárikovo námestie 6, 818 06 Bratislava

I. - Basic information

I.1 - Surname
Nakládal
I.2 - Name
Dalibor
I.3 - Degrees
PharmDr., PhD., PhD.
I.4 - Year of birth
1991
I.5 - Name of the workplace
Clinical Research Unit, Comenius University Science Park
I.6 - Address of the workplace
Ilkovičova 8, 841 04 Bratislava, Slovakia
I.7 - Position
scientific researcher
I.8 - E-mail address
nakladal2@uniba.sk
I.9 - Hyperlink to the entry of a person in the Register of university staff
https://www.portalvs.sk/regzam/detail/45700?do=filterForm-submit&surname=Nakl%25C3%25A1dal&employment_state=yes&filter=Vyh%25C4%25BEada%25C5%25A5
I.10 - Name of the study field in which a person works at the university
Pharmacology
I.11 - ORCID iD
0000-0003-0900-0130

II. - Higher education and further qualification growth

II.1 - First degree of higher education
II.2 - Second degree of higher education
II.a - Name of the university or institution
Faculty of Pharmacy, Comenius University in Bratislava
II.b - Year
2015
II.c - Study field and programme
Pharmacy
II.3 - Third degree of higher education
II.a - Name of the university or institution
University of Groningen, The Netherlands; Faculty of Pharmacy, Comenius University in Bratislava
II.b - Year
2022; 2019
II.c - Study field and programme
Life Sciences; Pharmacology
II.4 - Associate professor
II.5 - Professor
II.6 - Doctor of Science (DrSc.)

III. - Current and previous employment

III.a - Occupation-position III.b - Institution III.c - Duration
scientific researcher Science Park, Comenius University in Bratislava september 2022 -
postdoc University Medical Center Groningen, The Netherlands 2020-2022
PhD student Department of Pharmacology and Toxicology, Faculty of Pharmacy, Comenius University in Bratislava 2015-2019
PhD student University Medical Center Groningen, The Netherlands 2015-2022

IV. - Development of pedagogical, professional, language, digital and other skills

V. - Overview of activities within the teaching career at the university

V.1 - Overview of the profile courses taught in the current academic year according to study programmes
V.2 - Overview of the responsibility for the delivery, development and quality assurance of the study programme or its part at the university in the current academic year
V.3 - Overview of the responsibility for the development and quality of the field of habilitation procedure and inaugural procedure in the current academic year
V.4 - Overview of supervised final theses
V.4.1 - Number of currently supervised theses
V.4.2 - Number of defended theses
V.5 - Overview of other courses taught in the current academic year according to study programmes

VI. - Overview of the research/artistic/other outputs

VI.1 - Overview of the research/artistic/other outputs and the corresponding citations
VI.1.1 - Number of the research/artistic/other outputs
VI.1.a - Overall
12
VI.1.b - Over the last six years
8
VI.1.2 - Number of the research/artistic/other outputs registered in the Web of Science or Scopus databases
VI.1.a - Overall
11
VI.1.b - Over the last six years
8
VI.1.3 - Number of citations corresponding to the research/artistic/other outputs
VI.1.a - Overall
129
VI.1.4 - Number of citations registered in the Web of Science or Scopus databases
VI.1.a - Overall
129
VI.1.5 - Number of invited lectures at the international, national level
VI.1.a - Overall
1
VI.2 - The most significant research/artistic/other outputs
1

Benedek Halmos; Anouk M. La Rose; Daisey Methorst; Anouk G. Groenen; Dalibor Nakládal; Venetia Bazioti; Mirjam H. Koster; Niels J. Kloosterhuis; Azuwerus van Buiten; Elisabeth M. Schouten et al. (2025) “SMC Abca1 and Abcg1 Deficiency Enhances Urinary Bladder Distension but Not Atherosclerosis.” Circulation Research. https://doi.org/10.1161/CIRCRESAHA.124.325103

2

Lambooy, S., Heida, A., Joschko, C., Nakladal, D., van Buiten, A., Kloosterhuis, N., Huijkman, N., Gerding, A., van de Sluis, B., Henning, R., & Deelman, L. (2023). Selective Hepatic Cbs Knockout Aggravates Liver Damage, Endothelial Dysfunction and ROS Stress in Mice Fed a Western Diet. International Journal of Molecular Sciences, 24(8), Article 8. https://doi.org/10.3390/ijms24087019

3

Vogelaar, P., Nakladal, D. (shared first authorship), Swart, D., Tkáčiková, Ľ., Tkáčiková, S., van der Graaf, A., Henning, R., & Krenning, G. (2021). Towards prevention of ischemia-reperfusion kidney injury: Pre-clinical evaluation of 6-chromanol derivatives and the lead compound SUL-138. European Journal of Pharmaceutical Sciences, 106033. https://doi.org/10.1016/j.ejps.2021.106033

4

Nakladal, D., Lambooy, S. P. H., Mišúth, S., Čepcová, D., Joschko, C. P., van Buiten, A., Goris, M., Hoogstra-Berends, F., Kloosterhuis, N. J., Huijkman, N., van de Sluis, B., Diercks, G. F., Buikema, J. H., Henning, R. H., & Deelman, L. E. (2022). Homozygous whole body Cbs knockout in adult mice features minimal pathology during ageing despite severe homocysteinemia. FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology, 36(4), e22260. https://doi.org/10.1096/fj.202101550R

5

Lambooy, S. P. H., Bidadkosh, A., Nakladal, D., van Buiten, A., Girgis, R. A. T., van der Graaf, A. C., … Deelman, L. E. (2017). The Novel Compound Sul-121 Preserves Endothelial Function and Inhibits Progression of Kidney Damage in Type 2 Diabetes Mellitus in Mice. Scientific Reports, 7(1). https://doi.org/10.1038/s41598-017-11582-6

6

Feenstra, L., Chatre, L., Bernay, B., Pontin, J., Mastik, M. F., Van Buiten, A., Nakládal, D., Star, B. S., Hillebrands, J., & Krenning, G. (2025). Calciprotein particle‐induced calcium overload triggers mitochondrial dysfunction in endothelial cells. The Journal of Physiology, JP287656. https://doi.org/10.1113/JP287656

7

Nakládal, D., Oerlemans, R., Molitorisová, M., Chomaničová, N., Zorkócy, G., Yoseif, C., Van Der Graaf, A. C., Stuchlík, S., Krenning, G., Groves, M. R., Heeres, A., Levarski, Z., Kyselovič, J., Henning, R. H., & Deelman, L. E. (2025). New homocysteine consumption assay for high-throughput screening of human cystathionine-β-synthase. SLAS Discovery, 32, 100234. https://doi.org/10.1016/j.slasd.2025.100234

VI.3 - The most significant research/artistic/other outputs over the last six years
1

Nakládal, D. (2022). Drug development and new targets for redox disturbances in experimental vascular disease: [Dissertation Thesis, University of Groningen]. https://doi.org/10.33612/diss.233870509

2

Nakladal, D., Sijbesma, J. W. A., Visser, L. M., Tietge, U. J. F., Slart, R. H. J. A., Deelman, L. E., Henning, R. H., Hillebrands, J. L., & Buikema, H. (2021). Perivascular adipose tissue-derived nitric oxide compensates endothelial dysfunction in aged pre-atherosclerotic apolipoprotein E-deficient rats. Vascular Pharmacology, 106945. https://doi.org/10.1016/j.vph.2021.106945

3

Nakladal, D., Buikema, H., Romero, A. R., Lambooy, S. P. H., Bouma, J., Krenning, G., … Deelman, L. E. (2019). The (R)-enantiomer of the 6-chromanol derivate SUL-121 improves renal graft perfusion via antagonism of the α1-adrenoceptor. Scientific Reports, 9(1). https://doi.org/10.1038/s41598-018-36788-0

4

Sijbesma, J. W. A., Van Waarde, A., Kristensen, S., Kion, I., Tietge, U. J. F., Hillebrands, J.-L., Bulthuis, M. L. C., Buikema, H., Nakladal, D., Westerterp, M., Liu, F., Boersma, H. H., Dierckx, R. A. J. O., & Slart, R. H. J. A. (2023). Characterization of a novel model for atherosclerosis imaging: The apolipoprotein E-deficient rat. EJNMMI Research, 13(1), 106. https://doi.org/10.1186/s13550-023-01055-5

5

Rodriguez, R. D., Huizing, E., Ünlü, Ç., Simonis, F. F. J., Bokkers, R. P. H., De Vries, J.-P. P. M., Schuurmann, R. C. L., Nakladal, D., Buikema, H., Hillebrands, J.-L., & Leuvenink, H. G. D. (2023). Validation of an ex vivo Flow Model Including Magnetic Resonance Imaging to Study the Effects of Endovascular Treatments on the Arterial Wall. Journal of Vascular Research, 60(1), 1–11. https://doi.org/10.1159/000529115

VI.4 - The most significant citations corresponding to the research/artistic/other outputs
1

Hernández-Camacho, Juan D., Michel Bernier, Guillermo López-Lluch, and Plácido Navas. 2018. “Coenzyme Q10 Supplementation in Aging and Disease.” Frontiers in Physiology 9:44. doi: 10.3389/fphys.2018.00044.

VI.5 - Participation in conducting (leading) the most important research projects or art projects over the last six years
1

Advancing innovative treatments targeting sulfur biochemistry (TREATSULF), APVV-23-0178, 2024-2026, principal investigator

2

High-throughput screening for the discovery of new drugs rescuing impaired sulfur metabolism in diabetic nephropathy and colon cancer, VEGA 1/0619/24, 2024-2026, principal investigator.

3

Discovery and development of new drugs for treatment of diabetic kidney disease: counteracting transsulfuration deficiency to improve defense against oxidative stress, APVV PP-MSCA2022-0001 (Marie Skłodowska-Curie Actions Seal of Excellence), 2022-2024, principal investigator

4

Discovery and development of new drugs for treatment of diabetic kidney disease: counteracting transsulfuration deficiency to improve defense against oxidative stress, Slovak Academic and Scientific Programme (SASPRO2) 3333/03/02, 2022-2025, research fellow.

5

European Lead Factory program (2021-2022): Ultra-High-Throughput-Screening of large academic/commercial library for the discovery of allosteric modulators of Cystathionine-β-synthase. PivotPark Screening Center in Oss, the Netherlands; Bio:ascent, Scotland.

VII. - Overview of organizational experience related to higher education and research/artistic/other activities

VIII. - Overview of international mobilities and visits oriented on education and research/artistic/other activities in the given field of study

IX. - Other relevant facts