Name and surname:
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prof. RNDr. Peter Mikuš, PhD.
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Document type:
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Research/art/teacher profile of a person
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The name of the university:
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Comenius University Bratislava
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The seat of the university:
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Šafárikovo námestie 6, 818 06 Bratislava
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III.a - Occupation-position | III.b - Institution | III.c - Duration |
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University teacher (assistant professor, associate professor, professor) | Faculty of Pharmacy, Comenius University in Bratislava | 2001-presence |
V.1.a - Name of the profile course | V.1.b - Study programme | V.1.c - Degree | V.1.d - Field of study |
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Analytical chemistry | Pharmaceutical chemistry | III (PhD.) | Pharmacy |
Pharmaceutical chemistry | Pharmaceutical chemistry | III (PhD.) | Pharmacy |
V.2.a - Name of the study programme | V.2.b - Degree | V.2.c - Field of study |
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Pharmaceutical Chemistry | III (PhD.) | Pharmacy |
V.3.a - Name of the field of habilitation procedure and inaugural procedure | V.3.b - Study field to which it is assigned |
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Pharmaceutical Chemistry | Pharmacy |
V.5.a - Name of the course | V.5.b - Study programme | V.5.c - Degree | V.5.d - Field of study |
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New trends in analytical chemistry | Pharmacy | II (Mgr.) | Pharmacy |
II (Mgr.) | Pharmacy | ||
Analytical chemistry II | Pharmacy | II (Mgr.) | Pharmacy |
Analytical monitoring of drug levels in pharmaceutical practice | Pharmacy | II (Mgr.) | Pharmacy |
Chiral capillary electrophoresis in Current Pharmaceutical and biomedical analysis
Mikuš, Peter
InTech
2012
ISBN 978-953-51-0657-9, Rijeka
Separation possibilities of three-dimensional capillary electrophoresis
Mikuš Peter, Koval Marián, Maráková Katarína, Piešťanský Juraj, Havránek Emil
Electrophoresis
2013
Volume 103, Page 294-300, DOI:10.1016/j.talanta.2012.10.047
Copper compounds in nuclear medicine and oncology
Krajčiová Dominika, Melník Milan, Havránek Emil, Forgácsová Andrea, Mikuš Peter
Journal of Coordination Chemistry
2014
Volume 67, Issue 9, Page 1493-1519, DOI:10.1080/00958972.2014.915966
On-line column coupled isotachophoresis-capillary zone electrophoresis hyphenated with tandem mass spectrometry in drug analysis: Varenicline and its metabolite in human urine
Piešťanský Juraj, Maráková Katarína, Veizerová Lucia, Galba Jaroslav, Mikuš Peter
Analytica Chimica Acta
2014
Volume 826, Page 84-93, DOI:10.1016/j.aca.2014.04.003
Novel sulfonamides incorporating 1,3,5-triazine and amino acid structural motifs as inhibitors of the physiological carbonic anhydrase isozymes I, II and IV and tumorassociated isozyme IX
Mikuš Peter, Krajčiová Dominika, Mikulová Mária, Horváth Branislav, Pecher Daniel, Garaj Vladimír, Bua Silvia, Angeli Andrea, Supuran Claudiu T.
Bioorganic Chemistry
2018
Volume 81, Page 241-252, DOI:10.1016/j.bioorg.2018.08.005
Novel electrochemical strategy for determination of 6-mercaptopurine using anodically pretreated boron-doped diamond electrode
Hanko Michal, Švorc Ľubomír, Planková Alexandra, Mikuš Peter
Journal of Electroanalytical Chemistry
2019
Volume 840, Page 295-304, DOI:10.1016/j.jelechem.2019.03.067
Porous graphitic carbon based chromatography hyphenated with mass spectrometry: A new strategy for profiling thiopurine nucleotides in patients with inflammatory bowel diseases
Pecher Daniel, Zelinková Zuzana, Lučeničová Jana, Peppelenbosch Maikel, Dokupilová Svetlana, Mikušová Veronika, Mikuš Peter
Analytica Chimica Acta
2020
Volume 1137,Page 64-73, DOI:10.1016/j.aca.2020.08.064
Advances in Chitosan-Based Nanoparticles for Drug Delivery
Mikušová Veronika, Mikuš Peter
International Journal of Molecular Sciences
2021
Volume 22, Issue 17, Article Number 9652, DOI:10.3390/ijms22179652
Comparative Study of Polysaccharide-Based Hydrogels: Rheological and Texture Properties and Ibuprofen Release
Mikušová Veronika, Ferková Jarmila, Žigrayová Dominika, Krchňák Daniel, Mikuš Peter
Gels
2022
Volume 8, Issue 3, Article number 168, DOI:10.3390/gels8030168
Synthetic Strategies and Computational Inhibition Activity Study for Triazinyl-Substituted Benzenesulfonamide Conjugates with Polar and Hydrophobic Amino Acids as Inhibitors of Carbonic Anhydrases
Bodnár Mikulová Mária, Kružlicová Dáša, Pecher Daniel, Supuran Claudiu T., Mikuš Peter
International Journal of Molecular Sciences
2020
Volume 21, Issue 10, Article number 3661, DOI:10.3390/ijms21103661
Recent advances (2019-2021) of capillary electrophoresis-mass spectrometry for multilevel proteomics
Chen, Daoyang
McCool, Elijah N.; Yang, Zhichang; Shen, Xiaojing; Lubeckyj, Rachele A.; Xu, Tian; Wang, Qianjie; Sun, Liangliang
Mass Spectrometry Reviews
DOI:10.1002/mas.21714
2021
citation to the article:A simple and rapid LC-MS/MS and CE-MS/MS analytical strategy for the determination of therapeutic peptides in modern immunotherapeutics and biopharmaceutics
Piestansky, Juraj; Barath, Peter; Majerova, Petra; Galba, Jaroslav; Mikus, Peter; Kovacech, Branislav; Kovac, Andrej
Journal of Pharmaceutical and Biomedical Analysis
Volume 189, Article Number 113449, DOI: 10.1016/j.jpba.2020.113449
2020
Combination therapy in inflammatory bowel disease - from traditional immunosuppressors towards the new paradigm of dual targeted therapy
Privitera, Giuseppe; Pugliese, Daniela; Onali, Sara; Petito, Valentina; Scaldaferri, Franco; Gasbarrini, Antonio; Danese, Silvio; Armuzzi, Alessandro
Autoimmunity Reviews
Volume 20, Issue 6, Article Number 102832, DOI:10.1016/j.autrev.2021.102832
2021
citation to the article:Positive pharmacokinetic effect of azathioprine co-medication on infliximab trough levels is dose-dependent
Polakovicova, Veronika; Kadleckova, Barbora; Lucenicova, Jana; Otottova, Katarina; Kinova, Sona; Mikus, Peter; Zelinkova, Zuzana
Digestive and Liver Disease
Volume 51, Issue 8, Page 1112-1116, DOI:10.1016/j.dld.2019.05.001
2019
Optical/electrochemical methods for detecting mitochondrial energy metabolism
Ji, Wenhui; Tang, Xiao; Du, Wei; Lu, Yao; Wang, Nanxiang; Wu, Qiong; Wei, Wei; Liu, Jie; Yu, Haidong; Ma, Bo
Chemical Society Reviews
Volume 51, Issue 1, Page 71-127, DOI:10.1039/d0cs01610a
2022
citation to the article:Overview and recent advances in electrochemical sensing of glutathione - A review
Hanko, Michal; Svorc, Lubomir; Plankova, Alexandra; Mikus, Peter
Analytica Chimica Acta
Volume 1062, Page 1-27, DOI:10.1016/j.aca.2019.02.052
2019
Portable Smartphone Platform Integrated with a Nanoprobe-Based Fluorescent Paper Strip: Visual Monitoring of Glutathione in Human Serum for Health Prognosis
Chu, Suyun; Wang, Haiqian; Du, Yuanxin; Yang, Fan; Yang, Liang; Jiang, Changlong
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
Volume 8, Issue 22, Page 8175-8183, DOI:10.1021/acssuschemeng.0c00690
2020
citation to the article:Ultra-high performance hydrophilic interaction liquid chromatography - Triple quadrupole tandem mass spectrometry method for determination of cysteine, homocysteine, cysteinyl-glycine and glutathione in rat plasma
Forgacsova, Andrea; Galba, Jaroslav; Mojzisova, Jana; Mikus, Peter; Piestansky, Juraj; Kovac, Andrej
Journal of Pharmaceutical and Biomedical Analysis
Volume 164, Page 442-451, DOI:10.1016/j.jpba.2018.10.053
2019
Metallacarborane Sulfamides: Unconventional, Specific, and Highly Selective Inhibitors of Carbonic Anhydrase IX
Gruner, Bohumir; Brynda, Jiri; Das, Viswanath; Sicha, Vaclav; Stepankova, Jana; Nekvinda, Jan; Holub, Josef; Pospisilova, Klara; Fabry, Milan; Pachl, Petr; Kral, Vlastimil; Kugler, Michael; Masek, Vlastimil; Medvedikova, Martina; Matejkova, Stanislava; Nova, Alice; Liskova, Barbora; Gurska, Sona; Dzubak, Petr; Hajduch, Marian; Rezacova, Pavlina
Journal of Medicinal Chemistry
Volume 62, Issue 21, Page 9560-9575, DOI:10.1021/acs.jmedchem.9b00945
2019
citation to the article:Novel sulfonamides incorporating 1,3,5-triazine and amino acid structural motifs as inhibitors of the physiological carbonic anhydrase isozymes I, II and IV and tumor-associated isozyme IX
Mikus, Peter; Krajciova, Dominika; Mikulova, Maria; Horvath, Branislav; Pecher, Daniel; Garaj, Vladimir; Bua, Silvia; Angeli, Andrea; Supuran, Claudiu T.
Bioorganic Chemistry
Volume 81, Page 241-252, DOI 10.1016/j.bioorg.2018.08.005
2018KEGA 027UK-4/2020
Principal investigator of the project
Creation of a comprehensive teaching material in the module "Analytical chemistry - Instrumental methods" of the master's study of pharmacy in English
VEGA 1/0514/22
Principal investigator of the project
"Advanced analytical monitoring of thiopurine nucleotides and antibodies to biologics in combination biological treatment of nonspecific inflammatory bowel diseases"
VEGA 1/0146/23
Deputy investigator of the project
"Study of medicinal substances based on glycosaminoglycans, sulfated heteropolysaccharides and live bacterial strains with immunomodulatory properties in vitro and in vivo conditions"
KEGA 041UK-4/2024
Principal investigator of the project
"Implementation of new knowledge from research and innovative teaching methods in the course Pharmaceutical technology"
EU R4 (09I03-03-V04-00157)
"Development of innovative analytical methods and validated protocols for studying the pharmacokinetics of Janus kinase inhibitors"
(Plán obnovy a odolnosti SR, Komponent: 9. Efektívnejšie riadenie a posilnenie financovania výskumu, vývoja a inovácií Plánu obnovy a odolnosti Slovenskej republiky, Investícia: 3. Excelentná veda)
VII.a - Activity, position | VII.b - Name of the institution, board | VII.c - Duration |
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Vice-Dean for International Relations and Faculty Development (including the study agenda of the Master's study program Pharmacy in English) | Faculty of Pharmacy, Comenius University in Bratislava | 2010-2013 |
Member / Chairman of the Commission for State Final Examinations (Pharmaceutical Chemistry, Pharmacology, Pharmacognosy, Pharmaceutical Technology, Social Pharmacy and Pharmacy, Master's Thesis Defense) | Faculty of Pharmacy, Comenius University in Bratislava | 2005-presence |
Chairman of the Commission for the Defense of Rigorous Thesis and Rigorous Examination | Faculty of Pharmacy, Comenius University in Bratislava | 2015-presence |
Commission chairman and guarantor of Pharmaceutical Chemistry (doctoral, habilitation and inauguration proceedings) | Faculty of Pharmacy, Comenius University in Bratislava | 2018-presence |
Commission member of Analytical Chemistry and Pharmaceutical Analysis at the Faculty of Natural Science, Comenius University in Bratislava and the Faculty of Pharmacy, Charles University in Prague, respectively | Faculty of Natural Science, Comenius University in Bratislava, Faculty of Pharmacy in Hradec Králové, Charles University in Prague | 2017-presence |
The American Chemical Society - member | The American Chemical Society | 2013-presence |
The Slovak Medical and Pharmaceutical Society - member | The Slovak Medical and Pharmaceutical Society | 2007-presence |
VIII.a - Name of the institution | VIII.b - Address of the institution | VIII.c - Duration (indicate the duration of stay) | VIII.d - Mobility scheme, employment contract, other (describe) |
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Consiglio Nazionale delle Ricerche, Istituto di Cromatografia | Roma, Italy | January-April 1996 | project: Tempus-Phare (JEP No 09101-95, 1995-98). Doctoral study and research stay (guarantor: Dr. Salvatore Fanali) |
VFU/Masaryk University in Brno, Faculty of Pharmacy; Charles University in Prague, Faculty of Pharmacy in Hradec Králové | Brno, Hradec Králové, Czech Republic | continuously | member of commissions for the defense of doctoral theses, member of habilitation commissions, member of inaugural commissions |
Review, editorial and evaluation activities:
Reviewer for the reputable international journals: Journal of Chromatography A, Journal of Chromatography B, Talanta, Journal of Pharmaceutical and Biomedical Analysis, Electrophoresis, Chirality, Molecules, Journal of Pharmacy & Pharmaceutical Sciences, Analytical and Bioanalytical Chemistry, Journal of Chromatographic Science, Journal of Separation Science, Analytica Chimica Acta, Analytical Chemistry, Chemical Communications, Journal of Medicinal Chemistry, Microchemical Journal, and others (since 2004)
Invited Editorial Board Member: Separations
European social fund project “Enhancing the quality of research and development of young scientists and teachers at FP CU” (2007). Evaluation committee member.
COST Action portASAP (“European network for the promotion of portable, affordable and simple analytical platforms”), member.
Invited lectures:
1. P. Mikuš, Kapilárna elektroforéza v analýze biologicky významných látok, XX. Sympózium, Syntéza a analýza liečiv a látok ovplyvňujúcich životné prostredie, Inpharmed – Interlab 2005, Bratislava, 11. 5. 2005.
2. P. Mikuš, Kapilárna elektroforéza so spektrálnou detekciou v analytickom hodnotení farmaceutických a klinických vzoriek, XXV. Sympózium, Syntéza a analýza liečiv a látok ovplyvňujúcich životné prostredie, Bratislava, 24. 09. 2010.
3. Peter Mikuš, Lucia Veizerová, Ján Kyselovič, INTERNATIONAL EDUCATION AND RESEARCH PROGRAM AT FACULTY OF PHARMACY COMENIUS UNIVERSITY IN BRATISLAVA: TECHNOLOGY OF RADIOPHARMACEUTICALS, «Aspects and the ways of development of nuclear medicine in Russia», Ekaterinburg, 27. - 28. October 2011
4. Peter Mikuš, Lucia Veizerová, Juraj Piešťanský, Katarína Maráková, Mass spectrometry analysis of drugs and their metabolites in multicomponent matrices with on-line sample preparation by means of column coupled electrophoresis, 1st Caparica Christmas Conference On Sample Treatment, on December 8-10, 2014 in Lisbon.
5. Mikuš P, Novotný L, Identification and quantification of major structural bleomycin forms (A2, B2) in pharmaceutical and biological matrices by HPLC-Q-TOFMS method, 5th Kuwait International Pharmacy Conference: Advances in cancer therapeutics from bench to bedside, February 1-3, 2015.
6. Peter Mikuš, Juraj Piešťanský, Katarína Maráková, Advanced CE-MS hyphenations for ultratrace determination of drugs and their metabolites in complex matrices, 16. ročník Školy hmotnostní spektrometrie (s medzinárodou účasťou), Frymburk 13. - 18. 9. 2015
7. Peter Mikuš, Juraj Piešťanský, Two-dimensional capillary electrophoresis separation and on-line tandem mass spectrometry detection of antigripal drugs and their metabolites in urine matrices, “International Conference and Expo on Separation Techniques”, August 10-12, 2015, San Francisco, USA
8. Peter Mikuš, Juraj Piešťanský, Katarína Maráková, Emil Havránek, Pavel Mučaji, Inovatívne analytické prístupy pre chirálne biologicky aktívne látky vo farmaceuticky významných systémoch, 45. konferencia Syntéza a analýza liečiv, Hradec Králové, 22. – 24. 06. 2016
9. Peter Mikuš, Juraj Piešťanský, Katarína Maráková. Ultra-trace determination of antihistamine enantiomers in urine by means of 2D chiral capillary electrophoresis hyphenated with triple quadrupole mass spectrometry, 14. Konferencia Súčasný stav a perspektívy analytickej chémie v praxi, Bratislava, 03.-06.05.2016
Awards: