Name and surname:
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Mgr. Lucia Lintnerová, PhD.
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Document type:
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Research/art/teacher profile of a person
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The name of the university:
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Comenius University Bratislava
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The seat of the university:
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Šafárikovo námestie 6, 818 06 Bratislava
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III.a - Occupation-position | III.b - Institution | III.c - Duration |
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assistant professor | Faculty of Pharmacy, Comenius University in Bratislava | 2013 - until now |
IV.a - Activity description, course name, other | IV.b - Name of the institution | IV.c - Year |
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Protection of animals used for scientific purposes and educational purposes (module: performing of procedures and projects) | Institute of postgraduate education of veterinary surgeons | 2015 |
Comenius University Science Park | Comenius Univerzity in Bratislava | 2014-2015 |
V.2.a - Name of the study programme | V.2.b - Degree | V.2.c - Field of study |
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Pharmacy | master | Pharmacy |
V.5.a - Name of the course | V.5.b - Study programme | V.5.c - Degree | V.5.d - Field of study |
---|---|---|---|
General and Inorganic Chemistry | Pharmacy | master | Pharmacy |
Organic chemistry 1 | Pharmacy | master | Pharmacy |
Principles of Molecular Modeling | Pharmacy | master | Pharmacy |
Bioorganic chemistry | Pharmacy | master | Pharmacy |
A development of chimeric VEGFR2 TK inhibitor based on two ligand conformers from PDB: 1Y6A complex - Medicinal chemistry consequences of a TKs analysis
Authors: Lintnerova, L Garcia-Caballero, M, Gregan, F, Melichercik, M, Quesada, AR, Dobias, J, Lac, J, Salisova, M, Bohac, A
Journal: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume: 72
Page: 146-159
DOI: 10.1016/j.ejmech.2013.11.023
Published: 2014
Chiral ligand induced geometrical type of isomerism in Schiff-base Copper (II) complexes with urease inhibitory activities
Authors: Valentová, J., Lintnerová, L., Sláviková, B., Baran, P.
Journal: Inorganica Chimica Acta
Volume: 558
paged: 1-8
article number: 121707 [online]
DOI: 10.1016/j.ica.2023.121707
Published: 2023
Analogues of Anticancer Natural Products: Chiral Aspects
Authors: Valentová, J., Lintnerová, L., Miklášová, N., Oboňová, B., Habala, L.
Journal: International journal of molecular sciences [elektronický dokument]
Volume: 24
Issue: 6
Pages: 1-23
article number: 5679 [online]
DOI: 10.3390/ijms24065679
Published: 2023
Synthesis and antiradical activity of novel copper(II) complexes of long chain reduced Schiff base ligands
Authors: Lintnerova, L, Valentova, J, Herich, P, Kozisek, J, Devinsky, F,
Journal: MONATSHEFTE FUR CHEMIE
Volume: 149
Issue: 5
Page: 901-911
DOI: 10.1007/s00706-017-2137-z
Published: 2018
Selected Methodologies Convenient for the Synthesis of N,5-Diaryloxazole-2-amine Pharmacophore
Authors: Lintnerova, L, Kovacikova, L, Hanquet, G, Bohac, A,
Journal: JOURNAL OF HETEROCYCLIC CHEMISTRY
Volume: 52
Issue: 2
Page: 425-439
DOI: 10.1002/jhet.2063
Published: 2015
ANTIRADICAL ACTIVITY OF L-GLUTAMINE, L-ASPARAGINE AND L-ASPARTIC ACID DERIVED REDUCED SCHIFF BASE COPPER(II) COMPLEXES
Authors: Lintnerova, L, Valentova, J, Devinsky, F
Journal: STUDIA UNIVERSITATIS BABES-BOLYAI CHEMIA
Volume: 61
Issue: 4
Page: 85-98
Published: 2016
The design and NMR structure determination of yttrium-oligopeptide tags for recombinant proteins and antibodies
Authors: Mudra, M, Breza, M, Lintnerova, L, Filo, J, Bauer, J
Journal: ACTA CHIMICA SLOVACA
Volume: 11
Issue: 2
Page: 120-133
DOI: 10.2478/acs-2018-0018
Published: 2018
Chirality in Anticancer Agents
Authors: Valentová, J., Lintnerová, L.
Book: Current Topics in Chirality - From Chemistry to Biology
Online: https://www.intechopen.com/chapters/77627
DOI: 10.5772/intechopen.98977
Publishes: 2020
Chiral ligand induced geometrical type of isomerism in Schiff-base Copper (II) complexes with urease inhibitory activities
Authors: Valentová, J., Lintnerová, L., Sláviková, B., Baran, P.
Journal: Inorganica Chimica Acta
Volume: 558
paged: 1-8
article number: 121707 [online]
DOI: 10.1016/j.ica.2023.121707
Published: 2023
Analogues of Anticancer Natural Products: Chiral Aspects
Autori: Valentová, J., Lintnerová, L., Miklášová, N., Oboňová, B., Habala, L.
Časopis: International journal of molecular sciences [elektronický dokument]
Ročník: 24
číslo: 6
strany: 1-23
číslo článku: 5679 [online]
DOI: 10.3390/ijms24065679
Publikované: 2023
Chirality in Anticancer Agents
Authors: Valentová, J., Lintnerová, L.
Book: Current Topics in Chirality - From Chemistry to Biology
Online: https://www.intechopen.com/chapters/77627
DOI: 10.5772/intechopen.98977
Publishes: 2020
Synthesis, biological evaluation, and molecular docking of new series of antitumor and apoptosis inducers designed as VEGFR-2 inhibitors
Authors: Abdallah, AE; Mabrouk, RR; Al Ward, MMS; Eissa, SI; Elkaeed, EB; Mehany, ABM; Abo-Saif, MA; El-Feky, OA; Alesawy, MS; El-Zahabi, MA
Journal: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Published: 2022
Volume: 37
Pages: 573-591
DOI: 10.1080/14756366.2021.2017911
Design, synthesis, and anti-proliferative evaluation of new quinazolin-4 (3H)-ones as potential VEGFR-2 inhibitors
Authors: El-Adl, K; El-Helby, AGA; Ayyad, RR; Mahdy, HA; Khalifa, MM; Elnagar, HA; Mehany, ABM; Metwaly, AM; Elhendawy, MA; Radwan, MM; ElSohly, MA; Eissa, IH
Journal: BIOORGANIC & MEDICINAL CHEMISTRY
Published: 2021
Volume: 29
Article number: 115872
DOI: 10.1016/j.bmc.2020.115872
Cu(II) and V(IV)O complexes with tri- or tetradentate ligands based on (2-hydroxybenzyl)-L-alanines reveal promising anticancer therapeutic potential
Authors: Ribeiro, N; Bulut, I; Cevatemre, B; Teixeira, C; Yildizhan, Y; Andre, V; Adao, P; Pessoa, JC; Acilan, C; Correia, I
Journal: DALTON TRANSACTIONS
Published: 2021
Volume: 50
Pages: 157-169
DOI: 10.1039/d0dt03331f
Discovery of new quinazolin-4(3H)-ones as VEGFR-2 inhibitors: Design, synthesis, and anti-proliferative evaluation
Authors: Eissa, IH; El-Helby, AGA; Mahdy, HA; Khalifa, MM; Elnagar, HA; Mehany, ABM; Metwaly, AM; Elhendawy, MA; Radwan, MM; ElSohly, MA; El-Adl, K
Journal: BIOORGANIC CHEMISTRY
Published: 2020
Volume: 105
Article number: 104380
DOI: 10.1016/j.bioorg.2020.104380
Current Scenario of 1,3-oxazole Derivatives for Anticancer Activity
Authors: Yan, XJ; Wen, J; Zhou, L; Fan, L; Wang, XB; Xu, Z
Journal: CURRENT TOPICS IN MEDICINAL CHEMISTRY
Published: 2020
Volume: 20
Pages: 1916-1937
DOI: 10.2174/1568026620666200624161151
Equilibria in Aqueous Cobalt(II)-Reduced Schiff BaseN-(2-hydroxybenzyl)alanine System: Chemical Characterization, Kinetic Analysis, Antimicrobial and Cytotoxic Properties
Authors: Wozniczka, M; Sutradhar, M; Pombeiro, AJL; Swiatek, M; Pajak, M; Gadek-Sobczynska, J; Chmiela, M; Gonciarz, W; Pasternak, B; Kufelnicki, A
Journal: MOLECULES
Published: 2020
Volume: 25
Article number: 3462
DOI: 10.3390/molecules25153462
Oxazole-Based Compounds As Anticancer Agents
Authors: Chiacchio, MA; Lanza, G; Chiacchio, U; Giofre, SV; Romeo, R; Iannazzo, D; Legnani, L
Journal: CURRENT MEDICINAL CHEMISTRY
Published: 2019
Volume: 26
Pages: 7337-7371
DOI: 10.2174/0929867326666181203130402
Recent advance in oxazole-based medicinal chemistry
Authors: Zhang, HZ; Zhao, ZL; Zhou, CH
Journal: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Published: 2018
Volume: 144
Pages: 444-492
DOI: 10.1016/j.ejmech.2017.12.044
Recent advances in the development of dual VEGFR and c-Met small molecule inhibitors as anticancer drugs
Authors: Zhang, J; Jiang, XD; Jiang, YN; Guo, MR; Zhang, SY; Li, JJ; He, J; Liu, J; Wang, JH; Ouyang, L
Journal: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Published: 2016
Volume: 108
Pages: 495-504
DOI: 10.1016/j.ejmech.2015.12.016
Increasing the binding affinity of VEGFR-2 inhibitors by extending their hydrophobic interaction with the active site: Design, synthesis and biological evaluation of 1-substituted-4-(4-methoxybenzyl) phthalazine derivatives
Authors: Eldehna, WM; Abou-Seri, SM; El Kerdawy, AM; Ayyad, RR; Hamdy, AM; Ghabbour, HA; Ali, MM; Abou El Ella, DA
Journal: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Published: 2016
Volume: 113
Pages: 50-62
DOI: 10.1016/j.ejmech.2016.02.029
Project number: UK/34/2010
Project leader: Mgr. Lucia Lintnerová, PhD.
Project title: Synthesis and testing of novel inhibitors of tumor neovascularization with VEGFR-2 receptor selectivity
Project number: FAF/4/2014
Project leader: Mgr. Lucia Lintnerová, PhD.
Project title: Synthesis of ligands of copper(II) complexes with antiradical activity
Project number: FAF/9/2015
Project leader: Mgr. Lucia Lintnerová, PhD.
Project title: Synthesis and study of copper(II) complexes prepared from reduced Schiff bases as ligands
Project number: FAF/11/2016
Project leader: Mgr. Lucia Lintnerová, PhD.
Project title: Strudy of antiradical activity and spectral properties of copper(II) complexes prepared from reduced Schiff bases as ligands
Project number: APVV-0516-12
Project leader: Dr.h.c. prof. Ing. Ferdinand Devínsky, DrSc.
Project title: Small molecules in biomedical research
Project number: VEGA 1/0346/16
Project leader: doc. PharmDr. Valentová Jindra, PhD.
Project title: Chiral drugs - stereospecific aspects of biological activity, metabolism and biological availability
Project number:VEGA 1/0145/20
Project leader: doc. PharmDr. Valentová Jindra, PhD.
Project title: New antineoplastics based on metalocomplexes and with mitochondria aimed activity
Project number: APVV-23-0349
Project leader: doc. Ing. Martin Pisárčik, CSc.
Project title: Optimalized composite gold and silver nanoparticles for biomedical applications
Project number: VEGA 1/0661/24
Project leader: doc. PharmDr. Valentová Jindra, PhD.
Project title: New type of metallopharmaceuticals with cytostatic effect targeting mitochondria and DNA
VII.a - Activity, position | VII.b - Name of the institution, board | VII.c - Duration |
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department secretary | Department of chemical theory of drugs, Faculty of Pharmacy, Comenius Univerzity in Bratislava | 1.9.2017 - present |
department teaching schedule administrator | Department of chemical theory of drugs, Faculty of Pharmacy, Comenius Univerzity in Bratislava | 1.9.2017 - present |
head of synthetic laboratory | Department of chemical theory of drugs, Faculty of Pharmacy, Comenius Univerzity in Bratislava | 1.9.2015 - present |
head of laboratory and classroom of molecular modeling | Department of chemical theory of drugs, Faculty of Pharmacy, Comenius Univerzity in Bratislava | 1.9.2015 - present |
VIII.a - Name of the institution | VIII.b - Address of the institution | VIII.c - Duration (indicate the duration of stay) | VIII.d - Mobility scheme, employment contract, other (describe) |
---|---|---|---|
University of Regensburg, Department of Organic Chemistry | Universitätsstraße 31, 93053 Regensburg, Germany | 1.4.2008 - 31.7.2008 | Erasmus/Socrates program, contact: Prof. Dr. Burkhard König, education and research mobility |
Skriptum for english program of Pharmacy for the subject Generanl and Inorganic Chemistry:
https://stella.uniba.sk/texty/FAF_inorganic_chem_laboratory_work_calculations.pdf
Skriptum for english program of Pharmacy for the subject Organic Chemistry 1: https://stella.uniba.sk/texty/FAF_NMLHLL_Laboratory_Techniques_Syntheses_Organic_Chemistry.pdf