Research/art/teacher profile of a person
Name and surname:
doc. PharmDr. Anna Paul Hrabovská, PhD.
Document type:
Research/art/teacher profile of a person
The name of the university:
Comenius University Bratislava
The seat of the university:
Šafárikovo námestie 6, 818 06 Bratislava

I. - Basic information

I.1 - Surname
Paul Hrabovska
I.2 - Name
Anna
I.3 - Degrees
Associate Professor, PharmD., PhD.
I.4 - Year of birth
1976
I.5 - Name of the workplace
Comenius University in Bratislava, Faculty of Pharmacy, Department od Pharmacology and Toxicology
I.6 - Address of the workplace
Odbojarov 10, 83232 Bratislava
I.7 - Position
Professor
I.8 - E-mail address
anna.paul.hrabovska@uniba.sk
I.9 - Hyperlink to the entry of a person in the Register of university staff
https://www.portalvs.sk/regzam/detail/3719
I.10 - Name of the study field in which a person works at the university
Pharmacology
I.11 - ORCID iD
0000-0003-1713-872X

II. - Higher education and further qualification growth

II.1 - First degree of higher education
II.a - Name of the university or institution
N/A
II.b - Year
N/A
II.c - Study field and programme
N/A
II.2 - Second degree of higher education
II.a - Name of the university or institution
Faculty of Pharmacy, Comenius University Bratislava
II.b - Year
1999
II.c - Study field and programme
Pharmacy
II.3 - Third degree of higher education
II.a - Name of the university or institution
Faculty of Pharmacy, Comenius University Bratislava
II.b - Year
2005
II.c - Study field and programme
Pharmaceutical Chemistry
II.4 - Associate professor
II.a - Name of the university or institution
Faculty of Pharmacy, Comenius University Bratislava
II.b - Year
2013
II.c - Study field and programme
Pharmacology
II.5 - Professor
II.6 - Doctor of Science (DrSc.)

III. - Current and previous employment

III.a - Occupation-position III.b - Institution III.c - Duration
Professor Faculty of Pharmacy, Comenius University Bratislava 2023 - present
Head of the Department of Pharmacology Faculty of Medicine, Slovak Medical University in Bratislava 2019 - present
Associate Professor Faculty of Pharmacy, Comenius University Bratislava 2013 - 2023
Assistant Professor Faculty of Pharmacy, Comenius University Bratislava 1999 - 2013
Visiting Professor Biomedical Research Center (BRC), University Hospital Hradec Kralove; Hradec Kralove, Czech Republic 2019 - 2020

IV. - Development of pedagogical, professional, language, digital and other skills

IV.a - Activity description, course name, other IV.b - Name of the institution IV.c - Year
Scientific Degree IIa Slovak Academy of Sciences 2011
Cell and gene regulation University of Nebraska Medical Center; Omaha, NE, USA 2002
Laboratory techniques in biochemistry and molecular biology University of Nebraska Medical Center; Omaha, NE, USA 2002
French language INSERM, Paríž, Francúzsko 2006
French language l'Institut français de Slovaquie 2004

V. - Overview of activities within the teaching career at the university

V.1 - Overview of the profile courses taught in the current academic year according to study programmes
V.1.a - Name of the profile course V.1.b - Study programme V.1.c - Degree V.1.d - Field of study
Pharmacology Pharmacy I. +II. (Master of Pharmacy, MPharm) Pharmacy
Toxicology Pharmacy I. +II. (MPharm) Pharmacy
Clinical Pharmacology and Pharmacotherapy Pharmacy I. +II. (MPharm) Pharmacy
Anatomy and Physiology Pharmacy I. +II. (MPharm) Pharmacy
Pharmacology General Medicine I. + II. (Doctor of Medicine, MD) General Medicine
Pharmacology Dental Medicine I. + II. (Doctor of Dental Medicine, DMD) Dental Medicine
Pharmacology Nursing / Midwifery / Physiotherapy / Radiological Technique / Physiological and Clinical Nutrition I. (Bachelor, Bc) Healthcare Sciences
V.2 - Overview of the responsibility for the delivery, development and quality assurance of the study programme or its part at the university in the current academic year
V.2.a - Name of the study programme V.2.b - Degree V.2.c - Field of study
Clinical Pharmacy III. („philosophiae doctor“, PhD) Pharmacy
Toxicology I. + II. (MPharm) Pharmacy
Pharmacology I.+II. (MD) Geneal Medicine
Pharmacology I. + II. (DMD) Dental Medicine
Nursing / Midwifery / Physiotherapy / Radiological Technique / Physiological and Clinical Nutrition I. (Bc) Healthcare Sciences
V.3 - Overview of the responsibility for the development and quality of the field of habilitation procedure and inaugural procedure in the current academic year
V.4 - Overview of supervised final theses
V.4.1 - Number of currently supervised theses
V.4.a - Bachelor's (first degree)
0
V.4.b - Diploma (second degree)
4
V.4.c - Dissertation (third degree)
2
V.4.2 - Number of defended theses
V.4.a - Bachelor's (first degree)
1
V.4.b - Diploma (second degree)
47
V.4.c - Dissertation (third degree)
4
V.5 - Overview of other courses taught in the current academic year according to study programmes
V.5.a - Name of the course V.5.b - Study programme V.5.c - Degree V.5.d - Field of study
Pharmacology Nursing / Midwifery / Physiotherapy / Radiological Technique / Physiological and Clinical Nutrition I., Bc Health Sciences

VI. - Overview of the research/artistic/other outputs

VI.1 - Overview of the research/artistic/other outputs and the corresponding citations
VI.1.1 - Number of the research/artistic/other outputs
VI.1.a - Overall
192
VI.1.b - Over the last six years
20
VI.1.2 - Number of the research/artistic/other outputs registered in the Web of Science or Scopus databases
VI.1.a - Overall
36 (WoS) / 39 (Scopus)
VI.1.b - Over the last six years
9 (WoS) / 7 (Scopus)
VI.1.3 - Number of citations corresponding to the research/artistic/other outputs
VI.1.a - Overall
376 (WoS) / 248 (Scopus) without selfcitation of all authors
VI.1.b - Over the last six years
160 (WoS) / 137 (Scopus) without selfcitation of all authors
VI.1.4 - Number of citations registered in the Web of Science or Scopus databases
VI.1.a - Overall
314 (WoS) / 248 (Scopus) without selfcitation of all authors
VI.1.b - Over the last six years
160 (WoS) / 137 (Scopus) without selfcitation of all authors
VI.1.5 - Number of invited lectures at the international, national level
VI.1.a - Overall
> 15
VI.1.b - Over the last six years
> 12
VI.2 - The most significant research/artistic/other outputs
1

Altered striatal function and muscarinic cholinergic receptors in acetylcholinesterase knockout mice‎ By: Volpicelli-Daley, LA; Hrabovska, A; Duysen, EG; et al. MOLECULAR PHARMACOLOGY  Volume: ‏ 64  Issue: ‏ 6  Pages: ‏ 1309-1316  Published: ‏ DEC 2003

  • 2003: 5.650 - IF; Q1 - JCR; Q1 – SJR;
  • cit 2023: 48 (WoS), 58 (Scopus)
2

Targeting of Acetylcholinesterase in Neurons In Vivo: A Dual Processing Function for the Proline-Rich Membrane Anchor Subunit and the Attachment Domain on the Catalytic Subunit‎ By: Dobbertin, Alexandre; Hrabovska, Anna; Dembele, Korami; et al. JOURNAL OF NEUROSCIENCE  Volume: ‏ 29  Issue: ‏ 14  Pages: ‏ 4519-4530  Published: ‏ APR 8 2009 

  • 2009: 7.178 - IF; Q1 - JCR; Q1 – SJR;
  • cit 2023: 57 (WoS), 54 (Scopus)
3

Optimal detection of cholinesterase activity in biological samples: Modifications to the standard Ellman's assay‎ By: Dingova, Dominika; Leroy, Jacqueline; Check, Abel; ... Hrabovska, Anna. ANALYTICAL BIOCHEMISTRY  Volume: ‏ 462  Pages: ‏ 67-75  Published: ‏ OCT 1 2014

  • 2014: 2.219 - IF; Q2 - JCR; Q2 – SJR;
  • cit. 2023: 51 (WoS), 51 (Scopus)
4

Near-complete adaptation of the PRiMA knockout to the lack of central acetylcholinesterase By: Farar, Vladimir; Mohr, Franziska; Legrand, Marie;...Hrabovska, Anna, Myslivecek Jaromir, Krejci Eric. JOURNAL OF NEUROCHEMISTRY Volume: 122 Issue: 5 Pages: 1065-1080 Published: SEP 2012

  • 2012: 3.973 - IF; Q2 - JCR; Q1 – SJR;
  • cit. 2023: 26 (WoS), 27 (Scopus)
5

A Novel System for the Efficient Generation of Antibodies Following Immunization of Unique Knockout Mouse Strains‎ By: Hrabovska, Anna; Bernard, Veronique; Krejci, Eric PLOS ONE Volume: ‏ 5 Issue: ‏ 9 Article Number: e12892  Published: ‏ SEP 23 2010

  • 2010:4.411 - IF; Q1 - JCR; Q1 – SJR;
  • cit. 2023: 18 (WoS), 21 (Scopus)
VI.3 - The most significant research/artistic/other outputs over the last six years
1

α7 nicotinic receptors play a role in regulation of cardiac hemodynamics. Targosova, Katarina; Kucera, Matej; Fazekas, Tomas; Kilianova, Zuzana; Stankovicova, Tatiana; Hrabovska, Anna. JOURNAL OF NEUROCHEMISTRY. 168(4), pp.414-427. doi: 10.1111/jnc.15821. Online ahead of print. PMID: 37017608, APR 2023

  • 2023: 4.2 - IF; Q1 – JCR, Q1 – SJR                  
  • Citation 2023: 4 (WoS) / 3 (Scopus)  


2

Serum butyrylcholinesterase as a marker of COVID-19 mortality: Results of the monocentric prospective observational study. Markuskova, Lucia; Javorova Rihova, Zuzana; Fazekas, Tomas; Martinkovicova, Anna; Havrisko, Martina; Dingova, Dominika; Solavova, Maria; Rabarova, Daria; Hrabovska, Anna. CHEMICO-BIOLOGICAL INTERACTION 381:110557. doi: 10.1016/j.cbi.2023.110557, AUG 2023

  • 2023: 4.7 - IF; Q1 – JCR, Q1 – SJR                  
  • Citations 2023: 2 (WoS) / 2 (Scopus)  


3

Cardiac nicotinic receptors show b-subunit-dependent compensatory changes By: Targosova, Katarina; Kucera, Matej; Kilianova, Zuzana; ...Hrabovska, Anna. AMERICAN JOURNAL OF PHYSIOLOGY - HEART AND CIRCULATORY PHYSIOLOGY 320(5), pp. H1975–H1984, 2021

  • 2021: 4.733 - IF; Q1 – JCR, Q1 – SJR                  
  • Citations 2023: 2 (WoS) / 2 (Scopus)  


4

Aortic butyrylcholinesterase is reduced in spontaneously hypertensive rats. Szmicseková, Kristina; Bies Piváčková, Lenka; Kiliánová, Zuzana; Slobodová, Ľubica; Křenek, Peter; Hrabovská Anna. PHYSIOLOGICAL RESEARCH 70(5):809-813. doi: 10.33549/physiolres.934669. Epub PMID: 34505519, NOV 2021.

  • 2021: 2.139 - IF; Q1 – JCR, Q2 – SJR                  
  • Citations 2023: 3 (WoS) / 3 (Scopus)


5

Expression of cholinesterases and their anchoring proteins in rat heart. Kilianova, Zuzana; Ciznarova, Natalia; Szmicsekova, Kristina; Slobodova, Lubica; Hrabovska, Anna. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 98(7), pp. 473–476, 2020.

  • 2020: 2.273 - IF; Q3 - JCR; Q3 - SJR
  • Citations 2023: 7 (WoS) / 6 (Scopus)


VI.4 - The most significant citations corresponding to the research/artistic/other outputs
1

Brunton LL, Hilal-Dandan R, Knollmann BC (2018) Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 13e. ISBN 978-1-25-958473-2. McGraw-Hill Education USA.    

2

Long, Jonathan Z.; Cravatt, Benjamin F. (2011) The Metabolic Serine Hydrolases and Their Functions in Mammalian Physiology and Disease. CHEMICAL REVIEWS 111(10), 6022-6063.

  • IF: 54.301, Q1  
3

Witten, I.B.; Lin, S.C; ...Deisseroth, K. (2010) Cholinergic Interneurons Control Local Circuit Activity and Cocaine Conditioning. SCIENCE 330(6011), 1677-1681.

  • IF: 50.3, Q1
4

Sarter, M; Parikh, V (2008) Choline transporters, cholinergic transmission and cognition. NATURE REVIEWS NEUROSCIENCE 6(1), 48-56.

  • IF: 33.162, Q1            
5

Guo, Zhiling; Zhang, Peng;...; Lynch, Iseult. Intranasal exposure to ZnO nanoparticles induces alterations in cholinergic neurotransmission in rat brain NANO TODAY. Volume35, Article Number 100977, DEC 2020

  • IF: 21.862, Q1


VI.5 - Participation in conducting (leading) the most important research projects or art projects over the last six years
1

name of the project: Therapeutic role of selective ChE inhibition in heart failure; grant scheme: Capital booster for R&D support schemes, 09I03-03-V06-00054; years: 2024 - 2026; position: PI

2

name of the project: Therapeutic role of selective ChE inhibition in heart failure; grant scheme: APVV-22-0541; years: 2023 - 2026; position: PI

3

name of the project: Participation of the cholinergic system in pathologies underlying metabolic syndrome; grant scheme: VEGA 1/0283/22; years of realization: 2021 – 2023; role of principal investigator in the project: principle investigator

4

name of the project: Biomarkers for severe COVID-19; grant scheme: VEGA 1/0283/22; years of realization: 2022 – 2024; role of principal investigator in the project: co- principle investigator

5

name of the project: Non-neuronal cholinergic system; grant scheme: Bourse de Governement Français; years of realization: 2017 – 2020; project cost: fellowship; role of principal investigator in the project: co-tutor/adviser

VII. - Overview of organizational experience related to higher education and research/artistic/other activities

VII.a - Activity, position VII.b - Name of the institution, board VII.c - Duration
Member of the Subcommittee on Generic Medicines State Institute for Drug Control 09/2009 - 12/2021
Slovak expert for European Medicines Agency (EMA) European Medicines Agency (EMA) 2015 - 2017
Member of the Scientific Board Faculty of Medicine, Masaryk University in Brno, Czech republic 01/2019 - present
Member of the Scientific Board Faculty of Medicine, Slovak Medical University in Bratislava 01/2020 - 11/2023
Evaluator of the accreditation dosiers National Accreditation Bureau for Higher Education, Czech republic 2019 - present
Member of the board for medical sciences The Slovak Research and Development Agency 2021 - present
member of Advisory Board International Advisory Board (IAB) on Cholinergic Mechanisms since 2022
member of Advisory Board International Advisory Board (IAB) on International meeting on Cholinesterases since 2022
Member of the Scientific Board Faculty of Pharmacy, Comenius University since 2023

VIII. - Overview of international mobilities and visits oriented on education and research/artistic/other activities in the given field of study

VIII.a - Name of the institution VIII.b - Address of the institution VIII.c - Duration (indicate the duration of stay) VIII.d - Mobility scheme, employment contract, other (describe)
Eppley Institute, University of Nebraska Medical Center Omaha, NE, USA 10/2001 – 12/2003 visiting researcher
Centre de Recherches du Service de Sante des Armees, Toxicology Dept La Tronche, France 05/2004 – 06/2004 mobility of Comenius University
Charles University, 1st Faculty of Medicine, Institute of Physiology Prague, Czech republic 04/2005 - 05/2005 APVV mobility grant
UFR Biomédicale Paris 5, INSERM U686, Biologie des Jonctions Neuromusculaires Paris, France 10/2005 – 06/2009 post-doc
CNRS UMR 8544, Ecole Normale Supérieure Paris, France 03/2009 – 05/2009 post-doc

IX. - Other relevant facts

IX.a - If relevant, other activities related to higher education or research/artistic/other activities are mentioned
  • Reviewer of grant applications submitted to the Agency for Research and Development Support (since 2014) and grant applications submitted to the Scientific Grant Agency of the Ministry of Education, Science, Research and Sports of the Slovak Republic and the Slovak Academy of Sciences (since 2015);
  • Peer-reviewer of papers submitted to the international CC and IF journals (from many, for example: Journal of Neurology, Neurosurgery, and Psychiatry, IF 7.144, since 2017; Current Alzheimer Research, IF 3.595, since 2018; Current Medicinal Chemistry IF 3.519, from 2010; Chemico-Biological Interactions, IF 3.308, from r. 2005)
  • Associate Editor for the Journal of Alzheimer's Disease (2016);
  • Guidepoint Professional Consultant;
  • Hameln rds., VULM; Gnnosis Consulting expert consultant - toxicological expertise and preclinical drug evaluation;
  • Reviewer of textbooks: Martina Čižmáriková and Peter Takáč (2019): Dosage forms and application routes of drugs with a focus on their importance in human medicine. ISBN 978-80-8152-753-1;
  • Regular contributor to the European Researchers' Night in Bratislava - popularizing science and bringing selected scientific topics closer to children and the general public
Date of last update
2024-09-25