MATLAB - SIMULINK I / Stefan Kozak, Slavomir Kajan. Bratislava: Slovak University of Technology, 1999 Matlab / Jela Babušíková. Bratislava: FMFI UK Library and Publishing Center, 2007
Kozák Š., Kajan S., Matlab - Simulink, 1. Slovak University of Technology in Bratislava, 1999. ISBN Dušek F., MatLab and Simulink, University of Pardubice, 2000
mathworks.com/help
Continuous assessment: activity
Examination: group project, practical computer exam
slovak
Format and conversion of variables, vectors and matrices
Programming environment, so-called M-file
Reading from a file and protting data
Creating functions
Graphical GUI environment
20/80
Students will learn the basics of using MATLAB software. They will be able to use MATLAB to calculate some mathematical problems, read files or write to files, plot computed data, create complex functions for reuse and create a graphical user interface GUI for their programs.
To master the fundamentals of the common language and basic technical terms of particular fields of study; with pre-intermediate students emphasis on reading technical texts and presentations of technical articles, application of French Internet websites.
Capelle Guy, Menand Robert: Le Nouveau taxi 1, Hachette FLE Paris, France 2009, ISBN 978-2-01-155548 - 9
test
French language is taught at two levels: beginner and intermediate. Students opt for one of them depending on whether they wish to obtain the fundamentals of the language or wish to maintain and/or improve previous knowledge of French.
100/0
To master the fundamentals of the common language and basic technical terms of particular fields of study; with pre-intermediate students emphasis on reading technical texts and presentations of technical articles, application of French Internet websites.
Capelle Guy, Menand Robert: Le Nouveau taxi 1, Hachette FLE Paris, France 2009, ISBN 978-2-01-155548 - 9
test
The subject continues the program of French language (1) and provides courses of essential and intermediate French language.
100/0
To master the fundamentals of the common language and basic technical terms of particular fields of study (depending on the student's level of German proficiency )
Appropriate study material is supplied by teacher based on the participants’level of German proficiency.
test
German language is taught at three levels: beginner, intermediate and advanced. Students opt for one of them depending on whether they need to learn the fundamentals or maintain and/or improve their previous knowledge.
This course’s focus is to master the fundamentals of the common language and basic technical terms of particular fields of study (depending on the student's level of German proficiency )
100/0
To master the fundamentals of the common language and basic technical terms of particular fields of study (depending on the student's level of German proficiency )
To master the fundamentals of the common language and basic technical terms of particular fields of study (depending on the student's level of German proficiency )
Appropriate study material is supplied by teacher based on the participants’level of German proficiency
test
German language is taught at two levels: beginner and intermediate. Students opt for one of them depending on whether they wish to obtain the fundamentals of the language or wish to maintain and/or improve previous knowledge of German.
This course’s focus is to to master the fundamentals of the common language and basic technical terms of particular fields of study (depending on the student's level of German proficiency )
100/0
To master the fundamentals of the common language and basic technical terms of particular fields of study (depending on the student's level of German proficiency )
To master the fundamentals of general Russian. The language level is A1.
Learning the Cyrillic (Russian) alphabet, gaining basic language competence, building up skills and confidence in dealing with unfamiliar authentic and semi-authentic texts.
The textbook: : Точка Ру A1 (Ольга Долматова, Екатерина Новачац), рracovné karty Падежи 1 (Л.С. Безкоровайная, В.Е. Штыленко).
test
To master the fundamentals of general Russian. The language level is A1.
Learning the Cyrillic (Russian) alphabet, gaining basic language competence, building up skills and confidence in dealing with unfamiliar authentic and semi-authentic texts.
The subject provides a course in Russian language for beginners.
100/0
Basic communication in Russian, developing other Russian language skills - listening comprehension, reading and writing.
To master the fundamentals of general Russian.
Learning the Cyrillic (Russian) alphabet, gaining basic language competence, building up skills and confidence in dealing with unfamiliar authentic and semi-authentic texts.
Textbook: Точка Ру A1 (Ольга Долматова, Екатерина Новачац), рracovné karty Падежи 1 (Л.С. Безкоровайная, В.Е. Штыленко).
test
To master the fundamentals of general Russian.
Learning the Cyrillic (Russian) alphabet, gaining basic language competence, building up skills and confidence in dealing with unfamiliar authentic and semi-authentic texts.
The subject continues the program of Russian language (1) and provides a course of Russian for beginners.
100/0
Basic communication in Russian, developing other Russian language skills - listening comprehension, reading and writing.
Krížom- Krážom Slovenčina 1, additional material to further support the covered topics.
tests
Course prerequisites:
https://fmph.uniba.sk/microsites/kjp/katedra-jazykovej-pripravy/poziadavky-na-udelenie-priebezneho-hodnotenia-aj1aj2aj3-ostatne-kurzy/
The sylabus is targeted at the comprehension of the basics of the Slovak language for the absolute beginners (A1).
100/0
This course is aimed for foreign students to learn the fundamentals of the Slovak language with the focus on basic communication as well as all other language skills- listening comprehension,reading and writing.
Krížom- Krážom Slovenčina 1, additional material to further support the covered topics
tests
Course prerequisites:
https://fmph.uniba.sk/microsites/kjp/katedra-jazykovej-pripravy/poziadavky-na-udelenie-priebezneho-hodnotenia-aj1aj2aj3-ostatne-kurzy/
The sylabus is targeted at the comprehension of the basics of the Slovak language for the absolute beginners (A1) and this course is a follow up course to the Slovak language course 1.
100/0
This course is aimed for foreign students to learn the fundamentals of the Slovak language with the focus on basic communication as well as all other language skills- listening comprehension,reading and writing.
Continual improvement of all language skills focused on communication/speaking, listening comprehension and writing. The emphasis is on discourse, lexicology and morphology, word-bank broadening of communicational English as well as English for specific purposes appropriate for university students. This course is a follow up of the previously taught ESP course.
Appropriate study material is supplied based on the participants’level of English by the lecturer.(Sources- The Guardian, The Herald Morning Sun. The Nine News, The West Australian, BBC News and podcasts, CNN podcasts).
tests, oral presentations, essays
tests, presentations, essays
Course prerequisites:
https://fmph.uniba.sk/microsites/kjp/katedra-jazykovej-pripravy/poziadavky-na-udelenie-priebezneho-hodnotenia-aj1aj2aj3-ostatne-kurzy/
This course’s focus is to broaden spoken/communicational English for students with B2/C1 level of English knowledge.
100/0
Continual improvement of all language skills focused on communication/speaking, listening comprehension and writing. The emphasis is on discourse, lexicology and morphology, word-bank broadening of communicational English as well as English for specific purposes appropriate for university students. This course is a follow up of the previously taught ESP course.
tests
Continual improvement of all language skills focused on communication/speaking, listening comprehension and writing. The emphasis is on discourse, lexicology and morphology, word-bank broadening of communicational/spoken English as well as English for specific purpose appropriate for university students. This course is a follow up of the Conversational English course 1.
Appropriate study material is supplied based on the participants’level of English by the lecturer.(Sources- The Guardian, The Herald Morning Sun. The Nine News, The West Australian, BBC News and podcasts, CNN podcasts).
tests, oral presentations, essays
tests, oral presentations, essays
Course prerequisites:
https://fmph.uniba.sk/microsites/kjp/katedra-jazykovej-pripravy/poziadavky-na-udelenie-priebezneho-hodnotenia-aj1aj2aj3-ostatne-kurzy/
This course’s focus is to broaden spoken/communicational English for students with B2/C1 level of English knowledge( Upper-Intermediate/Lower Advanced).
100/0
Continual improvement of all language skills focused on communication/speaking, listening comprehension and writing. The emphasis is on discourse, lexicology and morphology, word-bank broadening of communicational/spoken English as well as English for specific purpose appropriate for university students. This course is a follow up of the Conversational English course 1.
tests
Improvement of common language, deepening the knowledge of technical terms, reading technical texts, presentations of popular scientific articles.
Capelle Guy, Menand Robert: Le Nouveau taxi 1, Hachette FLE Paris, France 2009, ISBN 978-2-01-155548 - 9
test
The subject provides a course of intermediate French language, covering not only general, but also technical language.
100/0
Improvement of common language, deepening the knowledge of technical terms, reading technical texts, presentations of popular scientific articles.
Menand Robert: Le Nouveau taxi 2, Hachette FLE, Paris, France 2009, ISBN 978-2-01-155551 - 9
test
The subject provides a course of intermediate French covering not only general, but also technical French language.
100/0
Deepening the knowledge of the common language and basic technical terms of particular fields of study (depending on the student's level of German proficiency).
Appropriate study material is supplied by teacher based on the participants’level of German proficiency.
test
The course is a follow-up to the German language (1,2). The subject provides a course of intermediate or advanced German language.
This course’s focus is to deepen the knowledge of the common language and basic technical terms of particular fields of study (depending on the student's level of German proficiency).
100/0
Master the basics of general language and basic professional terminology of individual fields of study (depending on the advanced level of students)
Deepening the knowledge of the common language and basic technical terms of particular fields of study (depending on the student's level of German proficiency).
Appropriate study material is supplied by teacher based on the participants’level of German proficiency.
test
The course is a follow-up to the German language (1-3). It provides a course of intermediate and advanced German language.
This course’s focus is to deepen the knowledge of the common language and basic technical terms of particular fields of study (depending on the student's level of German proficiency).
100/0
Master the basics of general language and basic professional terminology of individual fields of study (depending on the advanced level of students)
Learning the handwritten Russian (Russian Cursive Cyrillic), developing further language skills, gaining knowledge of Russian culture, history and way of life, pre-intermediate to intermediate grammar and vocabulary.
Точка Ру A2 (Ольга Долматова, Екатерина Новачац) a Short Stories in Russian (Olly Richards, Alex Rowlings)
test
Learning the handwritten Russian (Russian Cursive Cyrillic), developing further language skills, gaining knowledge of Russian culture, history and way of life, pre-intermediate to intermediate grammar and vocabulary.
The course "Russian for Intermediate Students" is a follow-up to "Russian for Beginners". The subject of the course is general Russian in the range appropriate to the given level.
100/0
Basic communication in Russian, developing other Russian language skills - listening comprehension, reading and writing.
Learning the handwritten Russian (Russian Cursive Cyrillic), developing further language skills, gaining knowledge of Russian culture, history and way of life, pre-intermediate to intermediate grammar and vocabulary.
Точка Ру A2 (Ольга Долматова, Екатерина Новачац) a Short Stories in Russian (Olly Richards, Alex Rowlings)
test
Learning the handwritten Russian (Russian Cursive Cyrillic), developing further language skills, gaining knowledge of Russian culture, history and way of life, pre-intermediate to intermediate grammar and vocabulary.
The course "Russian for Intermediate Students" is a follow-up to "Russian for Beginners". The subject of the course is general Russian in the range appropriate to the given level.
100/0
Learning the handwritten Russian (Russian Cursive Cyrillic), developing further language skills, gaining knowledge of Russian culture, history and way of life, pre-intermediate to intermediate grammar and vocabulary.
Krížom-Krážom Slovenčina 2, additional material to further support the covered topics.
tests
Course prerequisites:
https://fmph.uniba.sk/microsites/kjp/katedra-jazykovej-pripravy/poziadavky-na-udelenie-priebezneho-hodnotenia-aj1aj2aj3-ostatne-kurzy/
The sylabus is targeted at the comprehension of all the language skills of the Slovak language , and it is a follow up course to the Slovak language course 2.
100/0
This course is aimed for foreign students to better comprehend all the language skills important to enable correct usage of the Slovak language – listening comprehension, reading, writing and speaking.
Krížom-Krážom Slovenčina 2, additional material to further support the covered topics.
tests
Course prerequisites:
https://fmph.uniba.sk/microsites/kjp/katedra-jazykovej-pripravy/poziadavky-na-udelenie-priebezneho-hodnotenia-aj1aj2aj3-ostatne-kurzy/
The sylabus is targeted at the comprehension of all the language skills of the Slovak language , and it is a follow up course to the Slovak language course 3.
100/0
This course is aimed for foreign students to better comprehend all the language skills important to enable correct usage of the Slovak language – listening comprehension, reading, writing and speaking.
Fyzikálne praktikum IV : Atómová fyzika a detekcia ionizujúceho žiarenia / Matej Florek ... [et al.]. Bratislava : Univerzita Komenského, 1988
Instructions can be found here http://www.dnp.fmph.uniba.sk/~kollar/navodnik.htm
Fyzikálne praktikum III : Optika / Zuzana Chorvátová ...[et al.]. Bratislava : Univerzita Komenského, 1984
Continuous assessment: protocols from completed exercises
Indicative assessment scale: A 90%, B 80%, C 70%, D 60%, E 50%
english
Subjective photometry and light detection, lens imaging, dispersion, properties of optical prism spectrograph, interference, two-beam light interference - Newtonian rings, polarization, sucrose optical activity, refractive index, abbe refractive index measurement by refractometer, light absorption examination, diffraction, Fresnel diffraction of light, Fraunhofer diffraction of light on a slit. Experiments in atomic physics (Franck - Hertz experiment, validation of Stefan-Boltzmann's law, range of alpha particles from Am241 in air), nuclear physics (statistical nature of nuclear processes, determination of gamma ray energy, verification of Compton scattering), applied nuclear physics (measurement of air radioactivity).
100/0
By completing the course, students will gain experimental skills with the used instrumentation. They will make sure of the agreement between experiments and theories that clarify them in the realized experiments.
Biological sequence analysis : Probabilistic models of proteins and nucleic acids / Richard Durbin ... [et al.]. Cambridge : Cambridge University Press, 1998
Understanding bioinformatics / Marketa Zvelebil, Jeremy O. Baum. New York : Garland Science, 2008
Homework assignments (30%), group project (10%), individual project (40%), weekly quizzes (10%), activity at practicals (10%). Grades: A 90%, B 80%, C 70%, D 60%, E 50%. More information on the course website.
Slovak, English
Basic concepts from probability, algorithms and machine learning. Sequencing and assembling genomes. Gene finding. Sequence alignment. Evolutionary models and phylogenetic trees. Comparative and population genomics. RNA structure. Motif finding and gene expression analysis. Protein structure and function. Selected current topics. Life science students will focus on understanding and correct application of these methods on real data.
https://fmfi-compbio.github.io/mbi/
100/0
Students will be familiar with basic problems and methods in bioinformatics; they will be able to choose an appropriate method for a given biological problem and to interpret its results.
Mathematical biology : 1. : An introduction / J. D. Murray. New York : Springer, 2002
Mathematical biology : 2. : Spatial models and biomedical applications / J. D. Murray. New York : Springer, 2003
Keener, J., Sneyd, J., Mathematical physiology: I. Cellular physiology, 2nd. ed., Springer, New York, 2008
Wilkinson, D., Stochastic modelling for systems biology, 2nd ed., Chapman & Hall/CRC, Boca Raton, 2012.
Continuous assessment: homework, exam during the semester
Exam: written and oral
Approximate grading scale: A 90%, B 80%, C 70%, D 60%, E 50%
Slovak, English
Biological modeling with ordinary differential equations: the principle of mass balance, mass action rule, scaling and nondimensionalisation, one-component models (Michaelis-Menten kinetics, gene autoregulation), multi-component models (biological switches, oscillators, epidemiology). Modeling with differential equations with delay. Models with spatial component: the reaction-diffusion systems, the spread of epidemics, pattern formation. Stochastic models: probability balance equation, Gillespie simulation algorithm, stochastic models of gene expression.
Passing this subject, students will gain a basic understanding and overview of methods in biological modeling.
Deepening of knowledge from the area of physical chemistry. Systematization and extension of physico-chemical knowledge from different areas (biochemistry, bioenergetics).
http://www.chem1.com/acad/webtext/virtualtextbook.html
independent work (homeworks - 20% of total score)
Continuous assessment: homework
Exam: oral
The evaluation of the subject takes place in the form of continuous (individual work -20% of total score) and final evaluation (oral exam). Successful completion of the course reflects the student's sufficient orientation in the issue. The course will be graded as provided the student demonstrates compliance with at least 51%. The conditions for successful completion of the course are in accordance with the Study Regulations of FMFI UK
Indicative assessment scale: A 90%, B 80%, C 70%, D 60%, E 50%
english
Thermochemistry, creative, reaction and bond enthalpies, their use. Fundamentals of chemical thermodynamics, chemical potential and its application to the study of equilibrium processes. Fugacity, fugacity coefficient, activity, activity coefficient. Chemical equilibrium, equilibrium constant and its dependence on state variables. Affinity of a chemical reaction, conditions of spontaneous chemical course. reactions. Acid-base reactions and the theory of acids and bases. Galvanic cell, electrode potential, its use for measuring physico-chemical quantities. Introduction to chemical kinetics. Reaction order, methods of determining the reaction order. Reaction mechanisms and their relation to the kinetic equation. Homogeneous and heterogeneous catalysis. Autocatalysis, oscillating reactions.
20/80
The student will have developed a basic apparatus for understanding the physical nature of chemical processes, which may be encountered in other subjects (biochemistry, bioenergetics, plasma physics) as well as with the principles of some analytical methods used e.g. in biophysics.
exam
P. Atkins, Quantum molecular mechanics, Oxford 2007.
P. Zahradník, R. Polák, Elements of Quantum Chemistry, Springer 1990.
Preliminary evaluation: test
Final exam: oral / written
Indicative evaluation scale: A 90%, B 80%, C 70%, D 60%, E 50%
Slovak in combination with English (some of the suggested readings are in English).
Methods of quantum chemistry. Heitler-London method. MO-LCAO method. Hartree-Fock method. Born - Oppenheimer's approximation. Method of density functional. Study of chemical reactivity. Molecules in solution and in the solid phase. Molecular dynamics. Electrical properties of molecules. Magnetic properties of molecules. Collision theories. Getting basic skills with the use of molecular modeling software.
40/60
Get an overview of the possibilities of using quantum-chemical methods to model systems in chemistry and biology.
Biological Imaging and Sensing / T. Furukawa (Ed.). Berlin: Springer, 2004; Chemical sensors and biosensors: Fundamentals and applications / Florinel-Gabriel Banica. Chichester: John Wiley, 2012; Introduction to biosensors: From electric circuits to immunosensors / Jeong-Yeol Yoon. New York: Springer, 2013; Surface-launched acoustic wave sensors: Chemical sensing and thin-film characterization / Michael Thompson and David C. Stone. New York: Wiley Interscience, 1997; Physicochemistry and hydrodynamics of Langmuir-Blodgett depositions: Influence of molecular level forces on the efficiency of deposition of perfectly ordered Langmuir nanofilms / M. Elena Diaz and Ramon L. Cerro. Saarbrücken : VDM Verlag Dr. Müller, 2008; Nanobiotechnology: Concepts, applications and perspectives / edited by Christof M. Niemeyer and Chad A. Mirkin. Weinheim: Wiley-VCH, 2004; The aptamer handbook: Functional oligonucleotides and their applications / edited by Sven Klussmann. Weinheim: Wiley-VCH, 2006.
,
P: semester work and its presentation
Z: test and oral examination (80/20)
Grade scale: A 90%, B 80%, C 70%, D 60%, E 50%
Definition and characteristics of the biosensor. Sensitive biological elements. Methods of immobilization of biological components on various surfaces. Nanotechnologies, methods of surface modification with nanomaterials. Electrochemical biosensors. Optical biosensors. Mass biosensors and thermal biosensors. Applications of biosensors. Methods of studying surfaces using atomic force microscopy (AFM) and atomic force spectroscopy.
By completing the course, the student acquires some knowledge about nanotechnologies, principles of construction and function of biosensors and their applications in biophysics, chemical physics and biomedicine.
C. Hill, Learning scientific programming with Python, 2nd edition, Cambridge University Press, 2020, ISBN 9781108778039; J.M. Zelle, Python programming:An introduction to computer science. Sherwood; Franklin, Beedle & Associates, 2010, ISBN 978-1887902991.
http://en.wikipedia.org/wiki/Object-oriented_programming
http://www.python.org/
http://www.scipy.org/
test
Introduction to practical and effective methods of numerical and application programming needed to solve problems related to biophysics: solving linear algebraic equations, interpolation and extrapolation, fast Fourier transform, Fourier and spectral applications, statistical description of data. Programming of A/D converters. On-line control of experimental equipment. Collection and processing of data from experimental units.
Introduction to the basics of numerical programming methods in biophysics, methods of control of experimental equipment, data acquisition and processing.
oral exam
H. Gould, J. Tobochnik, W. Christian: An introduction to computer simulation methods : Applications to physical systems, San Francisco : Pearson, 2007
D. Frenkel, B. Smit: Understanding Molecular Simulation, Academic Press, 2002
Používateľský manuál a návody (tutorials) k programu GROMACS (https://www.gromacs.org) a Amber (https://www.amdbermd.org)
Laboratory and computer experiment, description of system with many
particles, Verlet and Gear integrator, simple thermostats and barostats,
intermolecular forces, corelation functions, simulations in NpT and NVT
microcanonical ensembles, border conditions, sampling and time step,
comparison of forcefields, system setting for simulations, simulation
convergence, trajcetory analysis - visual inspection, analysis of RMSD,
molecule fluctuations, radial distribution function (RDF), moment of
gyration, dihedral angles, principal component analysis (PCA),
estimation of interacting energies, entropies, analysis of interaction
between parts of simulates system - e.g. hydrogen bonds, parametrisation
of molecules, polarizable forcefields, combined quantum-classic
simulations (QM/MM), simulated annealing, parallel tempering - replica
exchange (REMD)
Familiarization of students with the basics of simulations by molecular
dynamics methods. Simulate simple systems using available software.
To present basic knowledge of experimental methods used in medical practice and medical research
Introduction to physics in modern medicine / Suzanne Amador Kane. Abingdon: Taylor &
Francis, 2003
Biomedical devices and their applications / D. Shi (Ed.). Berlin: Springer, 2004
Methods in modern biophysics / Bengt Nölting. Berlin: Springer, 2006
Introduction to experimental biophysics: Biological methods for physical scientists / Jay Nadeau. Boca Raton: CRC Press, 2012
Biomedical applications of introductory physics / Jack A. Tuszynski, John M. Dixon. Hoboken, N.J.: Wiley, 2002
Final examination: oral exam
Indicative evaluation scale: A 90%, B 80%, C 70%, D 60%, E 50%
Slovak, English
Introduction to laboratory methods (handling of chemicals, preparation of solutions, pH measurement), separation methods of biological samples (electrophoresis, centrifugation, distillation, extraction), introduction to chromatographic methods (paper, thin film, ion exchange , gel, affinity, capillary, gas, HPLC, supercritical), flow cytometry, microscopic techniques (light microscopy, dark field microscopy, phase contrast, polarized microscopy, electron microscopy - SEM, TEM, fluorescence and confocal microscopy), polymerase chain reaction, spectroscopic methods (UV/VIS, fluorescence, circular dichroism, mass, Raman, infrared spectroscopy), ultrasound
0/100
Upon completion, the student will gain knowledge of the principles, basic schemes and applications of experimental physical methods in medical practice and research.
exam
To gain a foundation of knowledge in selected methods of medical physics as well as their applications in the experimental and clinical practice in medicine.
Introduction to physics in modern medicine / Suzanne Amador Kane. Abingdon : Taylor & Francis, 2003
Biomedical devices and their applications / D. Shi (Ed.). Berlin: Springer, 2004
Methods in modern biophysics / Bengt Nölting. Berlin: Springer, 2006
Introduction to experimental biophysics: Biological methods for physical scientists / Jay Nadeau.
Boca Raton: CRC Press, 2012
Biomedical applications of introductory physics / Jack A. Tuszynski, John M. Dixon. Hoboken, N.J.: Wiley, 2002
Final examination: oral exam
Continuous assessment: A 90%, B 80%, C 70%, D 60%, E 50%
Slovak, English
Force microscopes, methods using static and dynamic scattering on colloids (suspensions), stem cells, methods using classical (equilibrium) thermodynamics in the study of biological systems, basics of dosimetry and radiation protection, imaging methods in medicine, radiotherapy, simulation medicine, methods for development drugs and monitoring their distribution in the body, thin films and interfaces, colloids, emulsions and gels, membrane lipid systems, rheology of biological fluids.
0/100
The student 1) will understand the physical principles of methods and devices standardly used in medical practice and / or research, 2) will be able to correctly analyze and interpret the results obtained with respect to experimental conditions or clinical characteristics.
exam
Introduction to practical aspects of methodology in medical physics and methods of data analysis.
Špeciálne praktikum z biomedicínskej fyziky a biofyziky / Libuša Šikurová (ed.). Bratislava 2007 (online)
Základy statistiky pro biomedicínské obory / Jana Zvárová. Praha: Karolinum, 2011 Physical Chemistry for the Chemical and Biological Sciences / Raymond Chang. Sausalito: University Science Books, 2000
Spectroscopy for the biological sciences / Gordon G. Hammes. Hoboken, N.J. : Wiley, 2005
Final evaluation: Assignment of each single practical task
During the semester, it is necessary to complete 5 laboratory exercises and to prepare 5 separate laboratory protocols (max. 10 points for each protocol). Credits will only be awarded to a student with all laboratory exercises completed and all protocols submitted.
Indicative assessment scale: A 45 points, B 40 points, C 35 points, D 30 points, E 25 points
Slovak, English
Quantitative morphology of muscular tissue
Paper chromatography
Spectroscopic quantitative analysis of proteins/nucleic acids
Measurement of quantum fluorescence yield
Laser-induced fluorescence of tissue components in medical diagnostics
Free enthalpy of p-nitrophenol dissociation
100/0
After completing the course, students will be able to work in biophysical, biomedical, chemical, biological laboratories, prepare and evaluate samples, operate instruments, evaluate the data obtained.
assignment of each single practical task
Students being knowledgeable about the methods and instruments, having a working knowledge of their characteristics, and being aware of their applications in the experimental and clinical practice.
Špeciálne praktikum z biomedicínskej fyziky a biofyziky / Libuša Šikurová (ed.). Bratislava 2007 (online).
Bioštatistika: model s náhodnými efektmi / Gejza Wimmer. Bratislava: Univerzita Komenského, 1999,
An Introduction to The Principles of medical imaging / Chris Guy, Dominic Ffytche. London: Imperial College Press, 2005.
Spectroscopy for the biological sciences / Gordon G. Hammes. Hoboken, N.J.: Wiley, 2005.
Final evaluation: Assignment of each single practical task During the semester, it is necessary to complete 5 laboratory exercises and to prepare 5 separate laboratory protocols (max. 10 points for each protocol). Credits will only be awarded to a student with all laboratory exercises completed and all protocols submitted. Indicative assessment scale: A 45 points, B 40 points, C 35 points, D 30 points, E 25 points
Slovak, English
Electron microscopy, High performance liquid chromatography, Preparation of monolayers at the water / air interface, Dimensions and zeta potential of liposomes, IR spectroscopy of biological samples, Density and specific volume of liposomes
100/0
After completing the course, students will be able to work in biophysical, biomedical, chemical, biological laboratories, prepare and evaluate samples, operate instruments, evaluate the data obtained.
assignment of each single practical task
To acquire the fundamental conception about pathological anatomy in the range of needful knowledge for students of Biomedical Physics interdisciplinary study.
To acquire the fundamental conception about possibility knowledge application acquired during the study of Biomedical Physics in human pathological anatomy and experimental pathology, in practise application and science.
Harsh Mohan: Patológia. LIBRARY FM CU
Zaviačič M. (Ed): Kompendium patológie I a II, Bratislava 2002, Univerzita Komenského. Currently content of lectures available at home page of Institute of pathology, prof. Jakubovský home page and RNDr Kopáni home page (in progress).
oral examination
Preliminary examination: oral (during exercise)
Final examination: exam
Indicative evaluation scale: A 90%, B 80%, C 70%, D 60%, E 50%
Slovak, English
Definition of pathology, history, sources of information, basic terminology. Methods in pathology (Autopsy and its significance, Biopsy a its role in detrmination of clinical diagnosis, histology, histochemistry). Optical methods of investigation and possibility of application in pathology (non-polarized and polarized light, fluorescence, phase contrast, differential interference contrast, dark field, confocal, transmission and scanning electron microscopy, transmitted and reflected light). Physical chemistry and its application in pathology (Raman spectroscopy, infrared spectroscopy, secondary ion mass spectroscopy (SIMS), energy-dispersive analysis (EDX). Pathology of the cell (cellular pathology). Pathology of the extracellular matrix. Metabolic and regressive alterations (dystrophy, atrophy, necrosis, death). Disturbances of the blood and lympha. Causes of the diseases. Pathology of the environment. General oncopathology. Selected problems of special oncopathology. Pathology of central nervous system. Pathology of oral cavity and respiratory tract. Pathology of digestive tract. Pathology of cardiovascular system. Pathology of the muscle, bone and joints. Osteoporosis as actual problem of contemporary public health. Pathology of urinary system and genital system. Skin pathology. Pathology of lymphatic and hemopoietic systems. Pathology of the spleen. Pathology of endocrine system. Chronicity test and cancerogenity from pathologist view.
20/80
After completing the course, students will be able to use the acquired knowledge about basic morphological changes in pathological conditions in the physical methods of biomedicine.
examination
Clarification and comprehension of cellular and molecular mechanisms of the origin, development and finishing up of pathological processes going on in a sick organism.
Hulín I. et al.: Patofyziológia a klinická fyziológia pre magisterské a bakalárske štúdium, Bratislava, SAP 2005, 593 s.,
Holzerová J. et al.: Experimentálne modely chorôb. Univerzita Komenského Bratislava, 2003, 113 s.,
Hulín I. et al.: Patofyziológia, 6. prepracované a doplnené vydanie, SAP 2002 - vybrané kapitoly.
orally at seminars
Preliminary examination: tests
Final examination: oral exam
Indicative evaluation scale: A 90%, B 80%, C 70%, D 60%, E 50%
Slovak, English
Pathophysiology of respiratory system, Pathophysiology of blood and haematologic system, Pathophysiology of cardiovascular system, Pathophysiology of kidneys and urinary system, Pathophysiology of endocrine system, Pathophysiology of nervous system, Pathophysiology of gastrointestinal tract, Pathophysiology of bones and joints, Fluid and electrolite disturbances, Disorders of acid-base homeostasis.
20/80
After completing the course, students will be able to use the acquired knowledge about the basic etiopathogenetic mechanisms of pathological conditions in the physical methods of biomedicine.
examination
Biomedicínska informatika - Jana Zvárová a kolektív, Karolinum, I. diel (2002), II. diel (2006), III. diel (2009), IV. diel (2010), V. diel (2013)
Medical Informatics, e-Health, Funfamentals and Applications, Editors: Alain Venot, Anita Burgum, Catherina Quantin, Springer (2014)
Preliminary evaluation: Active participation, semestral project
Final exam: test
Indicative evaluation scale: A 90%, B 80%, C 70%, D 60%, E 50%
Slovak, English
Introduction to health and medical informatics. Healthcare organization. National Health and Administrative Registers. Informatization of society (information society). Information systems and technologies - hospital, ambulance, management of medical facilities, laboratories, examinations, pharmacies. Modern technical equipment of medicine. Industry 4.0, cyber-physical systems, Big Data, Cloud Computing, exponential technologies, augmented and virtual reality in medicine. Open data in medical research. Electronic healthcare implementation program, e-Health, electronic medical record, electronic signature, GDPR. Telemedicine. The human body - a source of biophysical, visual and acoustic information. Visible Human Project, Human Genome Project. News in medical informatics.
30/70
After completing the course, students will be able to work witth basic current information and management technologies used in the medical environment - with computer science, health and management basics of health and medical informatics and e-Health system.
Data a znalosti v biomedicíně a zdravotníctví / editoři Jana Zvárová, Lenka Lhotská, Vladimír Přibík. Praha : Karolinum, 2010
Visualization in medicine : theory, algorithms, and applications / Bernhard Preim, Dirk Bartz. Burlington, Mass. : Morgan Kaufmann, 2007
Introduction to physics in modern medicine / Suzanne Amador Kane. Abingdon : Taylor & Francis, 2003
Biomedical signal image processing / Kayyvan Najarian, Robert Splinter. Boca Raton, Fla. : Taylor & Francis, 2006
Mathematical biology : 2. : Spatial models and biomedical applications / J. D. Murray. New York : Springer, 2003
Preliminary examination: test
Final examination: exam
Indicative evaluation scale: A 90%, B 80%, C 70%, D 60%, E 50%
Slovak, English
Zdrojový text
1 408 / 5 000
Výsledky překladu
1. Introduction: Basic model for medical diagnostics and selected topics from probability. (diagnostic test efficiency, binomial distribution - Bayesian probability, a priori and a posteriori probabilities). 2. The case of Sally Clark: Which probabilities are and which are not relevant. Principles of induction, P (data
H0) ≠ P (H0
data). The most common errors in probabilistic and statistical reasoning. 2. Therapy: results of an intervention in an indeterminate initial state. Measurement of therapy results. James-Stein and hidden variables. To vaccinate or not to vaccinate. Cost-benefit analysis: how the patient counts, how the doctor and how the insurance company. 4. Selected diagnostic methods: Radiodiagnostics (electromagnetic radiation detectors - dynamic range and noise depending on intensity and exposure time - mammography, and again cost-benefit analysis), biochemical diagnostic tests (minimum detectable concentrations - specificity). 6. Evidence base of medicine. What is verified and what is not. Cochrane collaboration. How to read a scientific paper. How to read an article on healthy eating. Measured, perceived and presented effects and risks. This is not a lecture on biostatistics. The student is required to have a basic knowledge of probability theory and practical statistics and the ability to read scientific papers in English. Each student will receive two texts from the professional and daily press for their independent study and will present their findings at a designated lecture.
30/70
After completing the course, students will be able to assess what criteria must meet the statement in order to be considered a verified or plausible fact. Can identify fundamental errors in the presentation of medical knowledge in scientific publications and the mass media. He knows the basic problems of clinical research and epidemiological studies, understands the basic limits of experimental methods and knows where to look for critical points of scientific publication. He verified these skills on a separate analysis of at least two papers from the available literature.
Biophysics for medical applications.
T. Hianik, Structure and physical properties of biomembranes and model membranes. Acta Physica Slovaca, 2006, vol. 56, No. 6, 687-805;
P.F. Dillon, Biophysics: a physiological approach, Cambridge University Press, 2012;
independent work
Cytoskeletal biophysics, cell division, intercellular connections and diseases arising from damage. Types of proteins with a focus on ion channels (IK). Sodium IK and their diseases. Calcium IK and their diseases. Potassium IK and their diseases. Chlorine IK, their diseases and an overview of voltage-dependent IK. Receptors, receptor-regulated channels and their diseases. IK and cytoskeleton. IK, regulated from the cytoplasmic region, intracellular signaling. Small proteins (hormones, neurotransmitters, local mediators). Other proteins, transporters, pumps. Protein disease research. Drugs, toxins.
examination
P.R. Hoskins, K. Martin, A. Thrush (Eds.) Diagnostic ultrasound, 2nd edition, Cambridge University Press, 2010, ISBN 9780511750885; B. Nölting, Methods in modern biophysics, Berlin, Springer, 2006, ISBN 978-3-540-27704-0; D.S. Ballantine, Jr. et al. Acoustic wave sensors: Theory, design, and physico-chemical applications, San Diego : Academic Press, 1997, ISBN 0-12-077460-7.
Mechanisms of acoustic wave propagation in the environment. Relation of acoustic wave propagation velocity with density and environmental compressibility. Piezoelectric effect. Pulse and resonance method for measurement of velocity and absorption of ultrasound. Acoustic biosensors. Ultrasound velocimetry. Ultrasound spectrometry. Acoustic impedance. Surface acoustic waves. Application of acoustics in biophysics and medicine. Diagnostics by ultrasound. Therapeutic ultrasound.
By completing the course, the student acquires a knowledge on the application of ultrasound in medical diagnostics.
Biophysics : An introduction / Roland Glaser. Heidelberg : Springer, 2012.
Klaessig, F.; Marrapese, M. Abe, S. (2011). Nanotechnology Standards. Nanostructure Science and Technology. Springer, New York
Torchilin, V (2006). "Multifunctional nanocarriers". Advanced Drug Delivery Reviews 58 (14): 1532–55.
Types of nanostructures - magnetic nanoparticles, fulleronosomes, transferosomes and liposomes. Physical properties of nanostructures: arrangement of lipid molecules, topological asymmetry, osmotic properties, permeability. Methods of preparation of nanostructures. Methods of optimal incorporation of substances - chemical and physical approaches. The influence of selected factors on the stability of their structure: processes of aggregation, fusion, solubilization, peroxidation and self-oxidation. Conditions for the stability of the nanostructure transmission system in the body. Mechanisms of cell-nanoparticle interaction: fusion, stable adsorption, endocytosis. Use in biophysics as cell model systems. Use in medicine - cancer chemotherapy, antimicrobial therapy, targeted drug delivery, electromagnetic hyperthermia. Application in diagnostics, magnetic nanoparticles as contrast agents in MR.
E. B. Podgoršak: Radiation physics for medical physicists, Heidelberg, 2010.
Interim evaluation: project
Final evaluation: exam
Ionizing radiation. Interaction of particles in the material environment. Effects of ionizing radiation at the level of cells, tissues and organs. Contamination by radioactive substances. Characteristics of clinical changes after irradiation. Repair of radiation damage. Radioprotective substances. Radiation monitoring and personal dosimetry. Radiation accidents and incidents. Care for persons irradiated with ionizing radiation. National regulations and international recommendations for protection against ionizing radiation.
Gaining knowledge about the mechanisms of ionizing radiation at the level of cells, tissues and organs and getting acquainted with the basic principles of radiation protection.
T. Hianik, Structure and physical properties of biomembranes and model membranes. Acta Physica Slovaca, 2006, vol. 56, No. 6, 687-805;
P.F. Dillon, Biophysics: a physiological approach, Cambridge University Press, 2012;
individual work
Structure and properties of nucleic acids. Superspiralization. DNA topology. DNA-protein interactions. DNA/RNA aptamers. The structure of proteins, peptide bond. Protein secondary structure. The types of interactions in macromolecules. The conformation of popypetide chain. Three dimensional structure of proteins. Phase transitions in biopolymers. (coil-globule transitions). The structure of biomembranes and their models. Membrane polymorphism. Phase transitions and membrane mechanical properties The mechanism of membrane conductivity. Passive and active ion transport. Membrane receptors. Mechanisms of mechanoreception and optical reception. Membrane theory of extication. Hodgkin and Huxley model. The structure of muscle and muscle fibers. The Hill experiments. Relation between force and load. Electrochemical coupling of muscle contraction. Theory of muscle contraction.
By completing the course, the student acquires a knowledge on the mechanisms of processes in the living systems on molecular level.
oral exam
Explanation of principles of magnetic resonance and MR imaging in clinical practice.
Literatúra dostupná voľne na webe napr.:
Webb, A.: CHAPTER 1: The principles of Magnetic Resonance, and Associated Hardware, in Magnetic Resonance Technology: Hardware and System Component Design, 2016, pp. 1-47. doi: 10.1039/9781782623878-00001 eISBN: 978-1-78262-387-8
test
General principles of imaging in medical practice. Basic concepts and physical principles of NMR and EPR. NMR spectrum. Relaxation mechanisms. Relationship between high resolution NMR spectrum parameters and compound structure. Multi-pulse NMR spectroscopy. 2D NMR spectroscopy. Principle of NMR imaging. Image parameters and contrast. Special imaging techniques, artifacts. Hardware and specific requirements for in-vivo measurements in humans. Localized spectroscopy and spectroscopic imaging (CSI). Practical demonstration of MR imaging and localized spectroscopy.
examination
Provide introduction to fundamentals of optical spectroscopy and its application in biophysics and biomedicine.
Kováč Š., Leško I., Spektrálne metódy v organickej chémii. Alfa, Bratislava 1980
Ferenčík M., Škárka B., a kol.: Biochemické laboratórne metódy. Alfa, Bratislava 1981
Lapčík Ľ., Pelikán P., Čeppan M.: Fotochemické procesy. Alfa, Bratislava 1989
Prosser V. a kol.: Experimentální metody biofyziky. Academia, Praha 1989
Laser-Tissue Interactions : Fundamentals and Applications / Markolf H. Niemz. Berlin : Springer, 2004
Spectroscopy for the biological sciences / Gordon G. Hammes. Hoboken, N.J. : Wiley, 2005iences / Gordon G. Hammes. Hoboken, N.J. : Wiley, 2005
laboratory work, test
Preliminary examination: laboratory task, test
Final examination: exam
Indicative evaluation scale: A 90%, B 80%, C 70%, D 60%, E 50%
Slovak, English
Electromagnetic radiation spectrum. Energetic states (levels) of molecules. Electronic transitions in molecules. Probabilities of absorption and emission, Einstein coefficients. Transition dipole moments. Absorption of UV VIS radiation, Lambert-Bear-Bouguer law. Information contained in absorption spectra, Frank-Condon principle. Techniques of absorption spectrophotometry. Preparation of samples for optical spectrophotometry. Chromophores. Effect of internal factors on absorption spectra. Effect of external factors on absorption spectra. Absorption of linearly polarized light. Applications of absorption spectroscopy. Fundamentals of formation of excited electronic states of molecules. Information contained in fluorescence spectra. Techniques of spectroflourimetry. Properties of electronically excited molecules. Effect of internal factors on fluorescence spectra. Stokes law, law of mirror symmetry. Quantum yield of fluorescence. Kinetics of luminiscence, lifetime of excited state. Fluorophores. Effect of external factors on fluorescence spectra. Fluorescence quenching, fluorescence anisotropy. Fluorescence probes and labels.
20/80
After completing the course, students will be able to apply optical spectroscopy theoretically and experimentally in research and practice, especially in the fields of biophysics, medicine and biochemistry.
exam
Introduction to Radiological Physics and Radiation Dosimetry / Frank Herbert Attix. Weinheim : Wiley-VCH , 2004
Radiation physics for medical physicists / E. B. Podgoršak. Heidelberg : Springer, 2010
Detekcia a spektrometria žiarenia alfa a beta / Štefan Šáro. Bratislava : Alfa, 1984
Experimentálna jadrová fyzika / Sergej Usačev ... [et al.]. Bratislava : Alfa, 1982
Examination: written and oral examination
Successful written part of the exam is a condition of participation in the oral exam
Share: (written / oral) 70/30
Indicative assessment scale: A 90%, B 80%, C 70%, D 60%, E 50%
Slovak, English
Basic terms and definitions, Interaction of radiation with matter, Detectors of nuclear radiation and elementary particles (Classification of detectors, Methods of signal generation in the detector, Methods of signal collection, Classification according to detector mode), General characteristics of detectors, Gas detectors Signal generation in ionization chamber (pulse), Signal duration, Ionization chamber with grating, Proportional computers (Gas amplification, Proportional computer design, Proportional computer properties, Detection efficiency), Geiger-Muller computers (Geiger discharge, Working gases, Extinguishing , Time characteristics, Efficiency, Utilization)
Coronary detectors. Spark detectors (ID). Scintillation detectors, Semiconductor detectors, Magnetic spectrometry methods, principles of using magnetic field for particle beam separation, focusing effects of magnetic field, spectrometer classification, Applications of detector systems (Radiation camera for healthcare, surface research, slow proton treatment of tumors using heavy particles, identification of isotopes in radioactive fallout, radiocarbon dating, dosimetry).
0/100
After completing the course, students will have an idea of the basic detection methods and detectors of ionizing radiation.
W. R. Leo, Techniques for nuclear and particle physics, Springer Verlag, Berlin, 1996
K. Kleinknecht, Detectors for particle radiation, Cambridge University Press, 1998
electronic text by e-mail
Preliminary examination: evaluation of protocols.
Final examination: presentation of the results.
Indicative evaluation scale: A 90%, B 80%, C 70%, D 60%, E 50%
Slovak, english
Determination of relative intensities of gamma lines using a scintillation detector. Use of liquid scintillation spectrometry for the analysis of alpha and beta radiation spectra. Principles of using a directional scintillation detector. Ge (Li) and HPGe detector characteristics. Methods for determining the peak efficiency of the HPGe detector. Spectrum analysis of a multicomponent radioactive source. Coincidence methods of gamma spectrometry, analysis of the 152Eu decay scheme. Activation analysis method. Spontaneous fission of nuclei (252Cf). Nucleus radius measurement.
80/20
Apply nuclear spectrometry solutions to practical problems.
Introduction to Experimental Biophysics Biological Mehods for Physical Scientists / Jay L.
Nadeau. Boca Raton, Florida: CRP Press, 2018
Methods of Experimental Physics / G. Ehrenstein, H. Lecar (Ed.). London: Academic Press, 1982
Methods in Molecular Biophysics – Structure, Dynamics, Function / Igor N. Serdyuk, Nathan R. Zaccai, Joseph Zaccai. New York: Cambridge University Press, 2007
Preliminary evaluation: Active participation and semestral projects
Indicative evaluation scale: A 90%, B 80%, C 70%, D 60%, E 50%
Slovak, English
During the semester, we visit several laboratories: high-performance liquid chromatography, flow cytometry, microbiology and virology, confocal microscopy, electron microscopy, laboratories of the Slovak Academy of Sciences, laboratories of the laser center and selected clinical institutes.
100/0
Upon completion, the student gets an overview and practical experience with the applications of experimental physical methods in medical practice and research.
BARD, A. FAULKNER, L. Electrochemical Methods: Fundamentals and Applications, 2nd Edition. New York: John Wiley and Sons, Inc., 2001. 833 s. ISBN 0 471 04372 9.
WANG, J., Analytical electrochemistry. Wiley-VCH: New York, 2001, ISBN: 978-0-471-67879-3
VACEK, J. OSTATNÁ, Bioelektrochemie: Nové směry v elektrochemii biologicky významných molekul, Univerzita Palackého v Olomouci, 2020. ISBN 978-244-5763-5.
Preliminary examination: individual work
Final examination: oral exam
Indicative evaluation scale: A 90%, B 80%, C 70%, D 60%, E 50%
Slovak, English
Definition of basic terms in bioelectrochemistry. Phase interfaces, electrical bilayer
Basic electrochemical methods (potentiostatic, galvanostatic and impedance). Interactions of biomolecules with surfaces. Electroanalysis of biopolymers (nucleic acids, proteins, glycans, ..), their structural changes and intermolecular interactions. Basic principles of biosensors operation. Glucose biosensors. Electrochemical applications in medicine. Bioelectrocatalysis, biofuel cells and biocapacitors. Bioenergy.
20/80
Gain knowledge about bioelectrochemical processes, the behavior of biomolecules on charged surfaces, the possibilities of electrochemical detection of medically important molecules, the principles of operation of electrochemical biosensors as well as electrochemical principles in bioenergetics.
To obtain insight into current methods of signal processing and on computer graphics.
Biological Imaging and Sensing / T. Furukawa (Ed.). Berlin : Springer, 2004
The Scientist and Engineer's Guide to Digital Signal Processing / Steven W. Smith. California Technical Pub, 1997
test
Preliminary examination: practical task
Final examination: test
Indicative evaluation scale: A 90%, B 80%, C 70%, D 60%, E 50%
Slovak, English
Image processing: physical principles of image registration, sampling, aliasing; image transformation, resampling, brightness transformations, binary operations; convolution, filtering, edge detectors, morphology and segmentation.
Data visualization: display and visualization of image and multidimensional data, acquisition of basic practical skills in available visualization system.
50/50
After completing the course, students will be able to process signals from biological objects - part 1.
exam
To obtain insight into current methods of signal processing and applications of computer graphics in biophysics and biomedicine.
Biological Imaging and Sensing / T. Furukawa (Ed.). Berlin : Springer, 2004
The Scientist and Engineer's Guide to Digital Signal Processing / Steven W. Smith. California Technical Pub, 1997
test
Preliminary examination: practical task
Final examination: test
Indicative evaluation scale: A 90%, B 80%, C 70%, D 60%, E 50%
Slovak, English
Signal processing: signal types and sources; analog signal preprocessing; signal transmission, transmission and recording; noise and signal filtering; frequency analysis; mathematical modeling and signal fitting (statistical analysis); signal compression and coding.
Applications: optical microscopy, tomography, acoustics, electrophysiology.
50/50
After completing the course, students will be able to process signals from biological objects - part 2.
exam
Biophysics : An introduction / Roland Glaser. Heidelberg : Springer, 2012
test
Subject and history of biomechanics. Cell membrane biomechanics and cell shape. Tissues as biomaterials. Distribution and mechanical properties of solid biomaterials. Liquid biomaterials. Newtonian and Maxwell fluids. Biomechanics of bones and joints. Musculoskeletal system - skeletal muscle system, joints, active movement of the joint, force on the skeletal elements, muscle energy and Hill's equation. Muscle work and muscle machine. Deformation and elastic properties of blood vessels. Analysis of blood velocity in blood vessels - laws of hemodynamics. Mechanical work of the heart. Biomechanics of hearing. Ear resonator system, hydrodynamic. sound transmission and hearing theory. Respiratory mechanics. Breathing resistances and breathing work. Respiratory gas transport. Bohr's equation for the calculation of anatomical dead space. Biophysical aspects of lung cleansing mechanisms.
Explanation of the basic principles of biomechanics in the living system.
exam
Radiation physics for medical physicists / E. B. Podgoršak. Heidelberg : Springer, 2010
Microdosimetry and Its Applications / Harald H. Rossi, Marco Zaider Springer, 1996
The evaluation of the course takes the form of a project which the student defends. The course will be graded with a passing grade provided that the student demonstrates at least 51% compliance.
Grading: A (100-91), B (90-81), C (80-71), D (70-61), E (60-51), Fx (50-0).
Slovak, English
Particle interaction and radiation energy storage in the material environment. Basic microdosimetric quantities. Experimental methods for obtaining microdosimetric spectra. Calculation of linear and specific energy spectra. Dose - effect relationship. Time course of the effects of ionizing radiation. Deterministic effects of ionizing radiation, Stochastic effects of ionizing radiation. Radiation effect of ionizing radiation with high LET (Bragg peak, relationship between LET and RBE, direct and indirect effect of ionizing radiation, radiation fractionation). Mathematical modeling of the dose-effect relationship (intervention and multi-intervention theory, two-way model, threshold-specific energy model, multimutation models, linear quadratic model, assumptions, derivation, utilization limits, survival curves and their interpretation). Exposure to radiation from natural and other sources. Epidemiological studies - a source of information on stochastic effects.
0/100
After completing the course, students will gain basic knowledge of microdosimetry and will be able to apply them to evaluate the radiation risk of ionizing radiation.
Základy buněčné biologie : úvod do molekulární biologie buňky / Bruce Alberts ... [et al.]. Ústí nad Labem : Espero Publ., [2001]
Molecular and cellular biophysics / Jack A. Tuszynski. Boca Raton : Chapman & Hall/CRC, 2008
Essential cell biology / Bruce Alberts ... [et al.]. New York : Garland Science, 2004
Physics in biology and medicine / Paul Davidovits. San Diego : Harcourt Academic Press, 2001
Preliminary examination: test
Final examination: exam
Indicative evaluation scale: A 90%, B 80%, C 70%, D 60%, E 50%
Slovak, English
1. Organization of living systems. Hierarchical systems. Non-cellular, single-celled and multicellular organisms.
2. Cell theory and chemical structure of the cell. Viruses. Prokaryotic and eukaryotic and cell.
3. Internal cell organization and construction principles: membrane, cytoskeletal and memory principle of functional cell organization. Structure and function of individual compartments.
4. Influence of external factors on cell structures.
5. Cell reproduction and cell cycle.
6. Vertical transmission of genetic information and types of reproduction.
7. Gene determination of multicellular organism traits. Basic genetic concepts.
8. Mendel's laws of inheritance. Autosomal and gonosomal inheritance.
9. Human genetics and population genetics.
10. Basic ecological concepts. Abiotic and biotic environmental factors.
11. Ecosystems and regulation in the ecosystem.
12. Mechanisms of evolution of living systems and human development.
30/70
Introduction to the general biology of cells and organisms.
· M. Laroussi et al. (eds.): Plasma medicine: applications of low-temperature gas plasmas in medicine and biology. Cambridge University Press, 2012
· A. Fridman and G. Friedman: Plasma medicine, Wiley 2013
· Z. Machala; K. Hensel; Y. Akishev (Eds.): Plasma for Bio-Decontamination, Medicine and Food Security, NATO Science for Peace and Security Series A: Chemistry and Biology, Springer 2012
· H-R. Metelmann, T. von Woedtke, K-D. Weltmann: Comprehensive Clinical Plasma Medicine, Springer 2018
Electronic texts available on the subject website
Preliminary evaluation: processing of literature on selected topic and its presentation
Final exam: oral
Indicative evaluation scale: A 90%, B 80%, C 70%, D 60%, E 50%
Slovak in combination with English (some of the suggested readings are in English).
Basic concepts of plasma physics, the formation of low-temperature plasma in electric discharges. Low-temperature plasma and pulsed electric fields for biological decontamination and sterilization of microorganisms (bacteria, spores, yeasts, biofilms) in air, water, surfaces, medical instruments, in living organisms. Thermal and chemical methods of disinfection/sterilization. Food spoilage prevention. Medical in-vivo, ex-vivo and in-vitro applications of plasma, plasma surgery, treatment of skin diseases, disinfection and wound healing, tooth decay and root canals. Selective induction of apoptosis and cancer treatment, cell manipulation.
Interaction of liquids with plasma and plasma activated fluids. Cell interaction with plasma, plasma activated liquids and pulsed electric field. Induced cellular and systemic processes in organisms. Importance of reactive oxygen and nitrogen forms, electroporation and electropermabilization of cell membranes. Bio-compatible and antimicrobial plasma surface treatment.
30/70
By completing the course the student will gain a comprehensive overview of the use of plasma and electric discharges, and pulsed electric fields in selected biomedical applications and therapeutic methods and an understanding of their basic principles.
Somorčík, J., Teplička, I. (2015). Štatistika zrozumiteľne. Bratislava : Enigma, 1. vydanie, 2015, 244 s. ISBN 9788081330421.
Základy statistiky pro biomedicínské obory / Jana Zvárová. Praha : Karolinum, 2011
Pekár, S. a Brabec, M. (2009). Moderní analýza biologických dat 1. Zobecněné lineární modely v prostředí R. Praha : Scientia, 1. vydanie, 2009, 225 s. ISBN 978-80-86960-44-9.
Pekár, S. a Brabec, M. (2012). Moderní analýza biologických dat 2. Lineární modely s korelacemi v prostředí R. Brno : Masarykova univerzita, 1. vydanie, 2009, 225 s. ISBN 978-80-210-5812-5.
Waczulíková, I., Slezák, P. (2015). Introductory Biostatistics. Bratislava: Comenius University, 1st Edition, 2015, 147 p. ISBN 978-80-223-3938-4.
Motulsky, H. (2014). Intuitive Biostatistics. New York : Oxford University Press, 3rd Edition, 2014, 540 p. ISBN 987-0-19-994664-8.
H.J. Motulsky and A Christopoulos, Fitting models to biological data using linear and nonlinear regression. A practical guide to curve fitting. 2004, Oxford University Press Inc., New York, 351 pages
Thomas A. Lang, Michelle Secic. How to report statistics in medicine : Annotated guidelines for authors, editors, and reviewers. Philadelphia : American College of Physicians, 1997
-
Preliminary evaluation: presenting homeworks
Final exam: oral / written written and oral exam
Indicative evaluation scale: A 90%, B 80%, C 70%, D 60%, E 50%
Slovak in combination with English (some of the suggested readings are in English)
-
Introduction to the problematics, an overview of basic research hypotheses as well as of experimental and clinical designs. Experimental planning (studies), formulation of working hypothesis, choice and character of factors (inputs), levels of factors, interactions, definition and measurement of response (outcome), sources of variability. Structure and organization of individual experiments, conditions for performing the experiment/study, methods for increasing the accuracy and reliability of the results (sample size, randomization, stratification). Analysis of variance in different experimental settings. Introduction to multivariate approaches. Simulated research situations: Description and analysis of the data set in simulated results, descriptive statistics, testing hypotheses about differences, testing bioequivalence, testing hypotheses about relationships, performance analysis of diagnostic tests. Graphical, tabular and textual presentation of results. Interpretation of results and formulation of research conclusions. The most common mistakes and shortcomings in biomedical research.
https://sluzby.fmph.uniba.sk/moodle/2-FBM-206
50/50
Upon completion, students are familiar with the general principles of scientific research, types of experimental and study designs in interdisciplinary biophysical and biomedical research, and statistical and analytical tools. In simulated research situations and by using active teaching and learning methods, students will learn to work in teams and apply the acquired knowledge in exemplary basic situations from formulating a working hypothesis, methodological scheme, through data collection and processing and interpretation of results in the context of research issues and research questions. Students will gain skills in operating analytical program systems. At the same time they train in the so-called soft skills (communication, argumentation and presentation of teamwork results).
Introduction to physico-chemical mechanisms of action of light on biological objects.
Prosser, V. a kol.: Experimentální metody biofyziky. Academia, Praha, 1989.
Lakowicz, J. R.: Principles of Fluorescence Spectroscopy, Springer, 2006.
Hammes, G. G, Hoboken, N. J.: Spectroscopy for the biological sciences. Wiely, 2005.
Niemz M. H., Laser-Tissue Interactions. Fundamentals and applications. Springer, Berlin,2004.
Fotakis, C., Papazoglou T. G., Kalpouzos, C.: Optics and Lasers in Biomedicine and culture.
Springer, Berlin, 1998.
Lowlor, D. W.: Photosynthesis. Third Edition. BIOS Scientific Publishers, Oxford, 2001.
Súčasné vedecké časopisy.
project
Preliminary examination: project
Final examination: exam
Indicative evaluation scale: A 90%, B 80%, C 70%, D 60%, E 50%
Slovak, English
Subject of photobiophysics. Sunlight penetrating the Earth. Chromophores and fluorophores in biological objects. Non-physiological and physiological photobiological processes. Photoinformation processes. Photosynthesis. Bioluminescence. Principles of phototherapy and photodiagnostics.
50/50
After completing the course, students will be able to use the acquired knowledge about physico-chemical mechanisms of light interaction with biological objects in biomedical applications and research.
exam
Introduction to Radiological Physics and Radiation Dosimetry / Frank Herbert Attix. Weinheim : Wiley-VCH , 2004
J. Šeda a kol.:Dozimetrie ionizujícího záření, SNTL Praha, 1983
J.E.Turner: Atoms, Radiation and Radiation Protection,WILEY-VCH, 2004
Final exam: oral / written
Indicative evaluation scale: A 90%, B 80%, C 70%, D 60%, E 50%
Slovak in combination with English (some of the suggested readings are in English).
The subject and place of dosimetry. Basic dosimetric quantities and relationships between them. Classification of dosimetric quantities and methods. Absolute methods for measuring activity and dose. Radiative equilibrium, Fano's theorem. Bragg-Gray theory of ionization in a cavity. Ionization methods of dosimetry. Tissue equivalence, energy dependence of dosimeters. Integral dosimetry methods, film and thermoluminescence dosimeters, track detectors. Perspectives of using other principles of dosimetry. Effect of radiation on man, cell damage, tissue radiosensitivity, reparation mechanism, stochastic and non-stochastic effects, dose-effect relationship. Principles of radiation protection.
0/100
The students will gain knowledge of basic dosimetric quantities, methods of measuring activity and dose, integral methods of dosimetry, biological effects of ionizing radiation and principles of radiation protection.
J.E. Martin: Physics for Radiation Protection, Wiley-VCH, 2000
W.L.Hendee,et al.: Radiation Therapy Physics, Wiley, 2005
Final exam: written
Indicative evaluation scale: A 90%, B 80%, C 70%, D 60%, E 50%
Slovak in combination with English (some of the suggested readings are in English).
Interaction of radiation with matter. Radionuclide sources of neutrons, alpha, beta and gamma radiation. Low-energy sources of X-radiation. X-ray beam shaping. Isotope therapeutic sources. Medical accelerators: linear electron accelerators, betatrons, cyclotrons, microtrons. Physical principles of radionuclide production. Radionuclides in nuclear medicine. CT, SPECT and PET tomography. Radiological imaging methods. Methods of radiation therapy: proton, neutron, capture, pion and heavy ion therapy.
0/100
Students will acquire basic knowledge about sources of ionizing radiation used in medicine, radiological imaging methods, use of radiation in diagnostics and therapy.
§ 51 of Act. no. 40/1964 Coll. The Civil Code as amended (hereinafter referred to as the “Civil Code”) and the Decree of the Ministry of Health of the Slovak Republic no. 84/2016 Z.z. laying down the defining characteristics of individual types of medical facilities.
Zamestnávanie zdravotníckych pracovníkov / Lenka Freel - 1. vyd. – Bratislava :
Univerzita Komenského, Právnická fakulta, 2020., - 99 s. ISBN: 978 – 80 – 7160 – 553 – 9
Biomedical research legislation:
- Regulation of the Government of the Slovak Republic no. 377/2012 Z. z. laying down requirements for the protection of animals used for scientific or educational purposes, similar to Act 39/2007 Coll. on veterinary care,
- Act No. 576/2004 on health care and on services related to health care, and Additional Protocol to the Convention on Human Rights and Biomedicine concerning Biomedical Research, ratified on 2007,
- Declaration of Helsinki (Ethical Principles of Human Participation Research), Protection of Personality and Medical Law, Convention for the Protection of Human Rights and Dignity of the Human Being with regard to the Application of Biology and Medicine, Convention on Human Rights and Biomedicine etc.
Legislation and documents of World Medical Association Declaration of Helsinki, ethical principles for medical research involving human subjects
Preliminary evaluation: >80% attendance
Slovak in combination with English (some of the suggested readings are in English)
Communication with director or head of the department as well as with the subject guarantor. Familiarization with the content of the Student Inteernship Agreement and with the conditions of professional practice and liability for damage. Completion of necessary health and safety training. Getting acquainted with the infrastructure of the workplace, training in the operation of selected instrumentation and software.
100/0
Students will consolidate their theoretical knowledge through practical experience comprising the student will consolidate theoretical and learn to apply this knowledge to practice in the field of study. They will learn to control instrumentation and operating software.They learn to work in a team, to communicate effectively and to take responsibility. They are trained in the soft skills (communication, argumentation and interpretation of teamwork results).
To master physical principles of electromagnetic diagnostic and therapeutic methods, to get acquainted with basic clinical applications.
Davidovits, P.,: Physics in biology and medicine. Academic Press/Elsevier, London, 5th ed., 2019. ISBN 978-0-12-81371.
MACFARLANE, P.W., OOSTEROM, A., PAHLM, O., KLIGFIELD, P., JANSE, M., CAMM, J. (Eds.): Comprehensive Electrocardiology. London: Springer, 2nd edition, Vol. 4, p. 2308. 2010. ISBN: 978-1-84882-045-6 – vybrané kapitoly.
MALMIVUO, J., PLONSEY, R.: Bioelectromagnetism - Principles and Applications of Bioelectric and Biomagnetic Fields. New York - Oxford: Oxford University Press, p. 641. 1995. ISBN: 978-0-19-505823-9 – vybrané kapitoly (https://www.bem.fi/book/bem.fi).
test
Anatomical and physiological bases of bioelectromagnetism. Bioelectric sources, conductors and their modeling. Theoretical methods in bioelectromagnetism. Electrical and magnetic measurements of electrical activity of nervous tissues and heart. Electrical and magnetic stimulation of nervous tissues and heart. Measurement of internal electrical properties of biological tissues. Other bioelectromagnetic manifestations. Principles of electrical and magnetic treatment methods. Safety and health protection during registration and application of electrical and magnetic signals (microshock, macroshock).
examination
Legislatíva biomedicínskeho výskumu:
- Zákon 39/ 2007 Z.z. o veterinárnej starostlivosti, Nariadenie vlády SR č. 377/2012 a Vyhláška 436/2012, ktoré ustanovujú požiadavky na ochranu zvierat používaných na vedecké alebo vzdelávacie účely,
- Zákon č. 576/2004 Z. z. o zdravotnej starostlivosti, ktorý vymedzuje biomedicínsky výskum,
- Helsinská deklarácia (Etické princípy výskumu s účasťou ľudských subjektov), ochrana osobnosti a medicínske právo, Dohovor o ochrane ľudských práv a dôstojnosti človeka v súvislosti s aplikáciou biológie a medicíny, Dohovor o ľudských právach a biomedicíne,
- Dokumenty Svetovej zdravotníckej organizácie (WHO)
Data a znalosti v biomedicíně a zdravotníctví / editoři Jana Zvárová, Lenka Lhotská, Vladimír Přibík. Praha : Karolinum, 2010
Katz, Michael J. (2009). From Research to Manuscript. A Guide to Scientific Writing. Springer Science + Business Media B.V., 210 p. e-ISBN 978-1-4020-9467-5
Štěpaník J. (2005) Umění jednat s lidmi 2 Komunikace. Grada publishing, Praha, 164 s. ISBN 80-247-0844-2.
Giertlová Klára (2004). Manažovať a koučovať systemicky? Áno. Co/Man, 158 s. ISBN
8089090079.
Plamínek J (2009). Konflikty a vyjednávání. Grada Publishing Praha. 136 s. ISBN 978-80-247-2944-2.
Helcl Z. (2013). Jak zvládnout 77 obtížných situací při prezentacích a přednáškách. Grada Publishing Praha. 224 s. ISBN 978-80-247-4770-5
Corfield Rebecca (2005). Připravujeme životopis. Jak zvýšit své šance na získání zaměstnání, o které se ucházíte (orig. Preparing your own CV. How to improve your chances of getting the job you want.) Ekopress, 130 s. ISBN 8086119939
Corfield R. (2005). Jak úspěšně zvládnout přijímací pohovor. Computer Press, a.s. Brno. 72 s. ISBN 80-251-0688-8.
Preliminary evaluation: homeworks / tests / team work - presentations
Final exam: oral / written presentation of the semestral project
Indicative evaluation scale: A 90%, B 80%, C 70%, D 60%, E 50%
Slovak in combination with English
Basic characteristics of the medical and healthcare environment, system of structure and management of medical facilities, defined powers and responsibilities. The Health Care Act, the Convention on Human Rights and Biomedicine and other EU legal standards for research involving human beings and animals. Ethics in medicine, protection of individual and personal data, professional and medical secrecy, patient vs. client. Basic and clinical research in medicine, work of the ethics committee, application form for the ethics committee, types of studies in biomedical research, procedures for the introduction of new diagnostic and therapeutic methods and related problems: medical, legislative, social, economic. Composition of interdisciplinary teams and reasons for their creation, personality factors of medical and health professionals, rights and obligations. Career planning after graduation, Personality questionnaire - estimation of personality profile and skills. Principles of communication, argumentation and presentation. Job market, job interview, professional CV, motivation letter. Levies.
https://sluzby.fmph.uniba.sk/moodle/2-FBM-236
70/30
After completing the course, students will master the basic principles of communication, argumentation and presentation, they are able to assess the pros and cons of teamwork in the medical and academic environment, the sources of possible conflicts and ways to resolve them.
Medical image processing reconstruction and restoration : Concepts and methods / Jiří Jan. Boca Raton, Fla. : Taylor & Francis, 2006
Biomedical devices and their applications / D. Shi (Ed.). Berlin : Springer, 2004
Selection of current articles in the field of biomedical physics.
Continuous evaluation: presentation of the project
Indicative assessment scale: A 90%, B 80%, C 70%, D 60%, E 50%
Slovak, English
Students will prepare a project and present it at a seminar on the latest trends in the development of physical methods for medical applications.
100/0
After completing the course, students will be able to obtain, present and discuss the latest information on physical methods used in medicine.
To elaborate diploma theses on the assigned issue.
According to the diploma theses.
individual theses
Preliminary examination: individual work evaluated by the supervisor and subsequently by the persons responsible for the study programme
Final examination: based on the status of the diploma thesis
Slovak, English
Preparation of literature survey on the basis of assigned subject of diploma theses aims determination, preparation of materials for selection of the methodic procedure for solution of the subject.
100/0
After completing the course, students will be able to obtain the necessary scientific information from the literature, analysis and synthesis of information. They will also be able to work with specific methods and devices according to the diploma thesis.
theses
Statistical Methods in Medical Research / P. Armitage, G. Berry, J.N.S. Matthews. Malden, Mass. : Blackwell Science, 2002
How to report statistics in medicine : Annotated guidelines for authors, editors, and reviewers / Thomas A. Lang, Michelle Secic. Philadelphia : American College of Physicians, 1997
Základy statistiky pro biomedicínské obory / Jana Zvárová. Praha : Karolinum, 2011
Výber aktuálnych článkov z oblasti diplomovej práce
Preliminary examination: individual work
Final examination: submission of diploma thesis
Slovak, English
Obtaining own results, their discussion, applications.
100/0
After completing the course, students will be able to obtain and discuss their own results and process them in writing.
Presentation of information from scientific literature and own results
According to the Diploma thesis
individual presentation, discussion
Preliminary examination: individual presentation, discussion
Indicative evaluation scale: A 90%, B 80%, C 70%, D 60%, E 50%
Presentation of information from literature and suggestion of topics for the Diploma thesis. Presentation and discussion of techniques and methods (experimental and theoretical) to be used in the thesis. Presentation of results with statistics, discussion.
Presentation of information from scientific literature and own results
According to the Diploma thesis
individual presentation, discussion
Preliminary examination: individual presentation, discussion
Indicative evaluation scale: A 90%, B 80%, C 70%, D 60%, E 50%
Presentation of own results with statistics, discussion.
M. B. Jackson: Molecular and cellular biophysics. Cambridge. Cambridge University Press, 2006
D. G. Nicholls, S. J. Ferguson: Bioenergetics 4th edition. London : Academic Press, 2013
D. Uhríková a kol.: Biofyzika - Vybrané kapitoly, Učebnica pre vysoké školy, Univerzita Komenského v Bratislave, 2015
P. F. Dillon, Biophysics: A physiological approach, Cambridge University Press, 2012;
B. Alberts et al., Základy buněčné biologie: Úvod do molekulární biologie buňky. Espero Publishing, 2001
oral state exam
Slovak, English
1. Structure and function of biopolymers, characteristic types of bonds, polymerization as a chemical process, types of biopolymers
2. Structure, physical properties and function of nucleic acids, genetic code, gene, information transfer
3. Structure, physical properties and function of proteins, peptide bond, types of protein structures
4. Structure, physical properties and function of glycans
5. Principles of cell structural organization, types of organelles and their importance, cell locomotor system, cell growth and division
6. Cell division, intercellular connections, necrosis, apoptosis, excessive cell proliferation (cancer)
7. Membrane biophysics, lipid bilayer, phase transitions, membrane models, role of lipids and proteins in the membrane
8. Passive transport of substances across membranes
9. Active transport of substances across membranes
10. Protein-lipid interactions, ion channels, exchangers, membrane receptors
11. Electrical properties of cells. Rest potential.
12. Physics of nerve impulse, structure of nerve cell, formation of action potential, Hodgkin-Huxley model
13. Synaptic transmission in the neuromuscular junction and in the central nervous system.
14. Molecular mechanisms of memory and learning
15. Muscle contraction, muscle structure, muscle proteins, biophysics of muscle contraction, mechanochemical coupling, basics of muscle regulation
16. Electrical activity of skeletal muscle cells and heart muscle.
17. Cell bioenergetics, mechanisms of membrane phosphorylation
18. Influence of physical factors on biosystems, influence of ionizing and non-ionizing radiation mechanisms
19. Photosynthesis of plants and bacteria
20. Photoreception, mechanisms of vertebrate and invertebrate vision
0/100
The student will repeat the theoretical and experimental methods of medical biophysics will gain the necessary overview.
T. Furukawa (Ed.): Biological Imaging and Sensing. Berlin, Springer, 2004
D. Shi (Ed.): Biomedical devices and their applications. Berlin, Springer, 2004
K. Najarian, R. Splinter.: Biomedical signal and image processing, second edition, CRP Press, Taylor & Francis, 2012
J. B. Pawley (Ed.): Handbook of biological confocal microscopy. New York, Springer, 2006
G. G. Hammes: Spectroscopy for the biological sciences. Wiley on line books, 2005
B. Nölting: Methods in modern biophysics, 3rd edition. Springer Verlag Berlin, 2009
oral state exam
Slovak, English
1. Thin films, micelles, liposomes and interfaces
2. Rheology of biological fluids
3. Microscopic techniques (light, polarized, confocal, electron microscopy)
4. Force microscopes
5. Optical absorption spectroscopy and its applications in cell diagnostics
6. Fluorescence spectroscopy, fluorescence microscopy
7. Mass, Raman, Infrared spectroscopy
8. Turbidimetry, nephelometry, analyzers in hematology - aggregometry
9. Flow cytometry and its use in medicine
10. Stem cells - classification, principle, use in medicine,
11. Separation methods of biological samples: electrophoresis, centrifugation, distillation, extraction
12. Dialysis; Calorimetry (differential scanning, isothermal titration)
13. Chromatographic methods (paper, thin film, ion exchange, gel, affinity, capillary, gas, HPLC)
14. Types of biological signals, their origin, sensing and significance in medicine
15. Statistical analysis of biosignals, mathematical modeling and signal fitting
16. Visualization of biosignals
17. Tomography - principle and types
18. X-ray and CT (computed tomography) - principles and medical applications
19. PET - Positron emission tomography, gammagraphy, scintigraphy
20. SPECT - Single photon emission computed tomography
21. Electrophysiological methods of cell study
22. Methods of recording and analysis of bio-electromagnetic signals
23. Phototherapy and photodiagnostics
24. Ultrasound in medicine
25. Radiotherapy
26. Methods of genetic modulation
27. Medical applications of magnetic resonance
28. Internet portal eHealth, information systems
0/100
Harsh Mohan: Patológia. KNIŽNICA LF UK
Examination: oral state exam
Slovak, English
1. Atrophy, dystrophy, necrosis
2. Hypertrophy, hyperplasia
3. Disorders of ventilation, diffusion and perfusion
4. Types of hypoxia
5. Lung diseases caused by pollutants in the inhaled air
6. Chronic respiratory diseases (bronchitis, emphysema, asthma)
7. Respiratory insufficiency
8. Anemia
9. Leukocyte disorders
10. Contraction-relaxation cycle of the heart muscle
11. Myocardial contractile function, pump function of the heart
12. Hypertrophy of the heart
13. Cardiomyopathy
14. Heart failure
15. Acquired heart defects
16. Congenital heart defects
17. Systemic arterial hypertension
18. Shock states
19. Atherosclerosis
20. Ischemic heart disease, angina pectoris, myocardial infarction
21. Pulmonary hypertension, cor pulmonale
22. Pathophysiology of cerebral circulation, intracranial hemorrhage, cerebral infarction
23. Electrophysiological basis of heart rhythm disorders
24. Disorders of sinusoatrial node function, disorders of A-V conduction, tachyarrhythmias
25. Diseases of the venous system
26. Disorders of glomerular function, glomerulonephritis, glomerulopathy
27. Renal failure
28. Diabetes mellitus
29. Intracranial hypertension
30. Epilepsy
31. Demyelinating and degenerative CNS disease
32. Liver cirrhosis, portal hypertension, ascites, liver failure
33. Jaundice
34. Generalized skeletal disorders
35. Dehydration, hyperhydration
36. Disorders of electrolyte economy (Na +, K +, Ca2 +)
37. Disorders of acid-base balance
38. Pathophysiology of the thyroid gland
39. Pathophysiology of parathyroid glands
0/100
The student will repeat the theoretical foundations of medicine and thus gain the necessary overview.
Introduction to physics in modern medicine / Suzanne Amador Kane. Abingdon : Taylor & Francis, 2003
Statistical Methods in Medical Research / P. Armitage, G. Berry, J.N.S. Matthews. Malden, Mass. : Blackwell Science, 2002
Biomedical signal image processing / Kayyvan Najarian, Robert Splinter. Boca Raton, Fla. : Taylor & Francis, 2006
Exam: Diploma thesis defense
Slovak, English
Presentation, defense and discussion of own results in the field of biomedical physics.
0/100
After completing the course, students will be able to present, defend and discuss their own results in the field of biomedical physics.
Basic practicing and improvement of locomotion skills in various selected sports: aerobics, basketball, volleyball, football, floorball, hockey, badminton, tennis, table tennis, swimming, body building, trampoline jumping, paddling. Development of a harmonic personality in the sense of “kalokagatia” – to cultivate the students´ mental and physical values.
Slovak, English
Practicing of the students´ game skills in collective sports: basketball, volleyball, football, floorball and hockey. Mastering of the basic technique of a particular sport discipline in other sports. In paddling, basic training on still and slightly flowing water. Development of coordination skills, improvement of articular mobility and cardiovascular system.
100/0
Grades: A 90%, B 80%, C 70%, D 60%, E 50%
The condition for the award of 1 or 2 credits is the completion of a multi-day course in its full scope, or the completion of one-day courses in the scope of 4 days. Candidates can apply to the leaders of individual courses. From the presented offer of courses, you can choose the one that suits your interests, abilities and deadlines.
Slovak
KTVŠ does not rent ski equipment.
The student can sign up for the outdoor sports courses offered by the department: skiing, snowboarding. The lessons in the courses are focused on the development of basic and special movement skills and mastering the techniques needed for the sports.
Acquisition and development of basic motor skills and abilities in selected sports: skiing and snowboarding. Mastering the correct technique of performing individual movements, which are necessary for skiing and snowboarding.
Grades: A 90%, B 80%, C 70%, D 60%, E 50%.
The condition for the award of 1 or 2 credits is the completion of a multi-day course in its full scope, or the completion of one-day courses in the scope of 4 days. Candidates can apply to the leaders of individual courses. From the presented offer of courses, you can choose the one that suits your interests, abilities and deadlines.
Slovak
KTVŠ will provide sports equipment.
The student can sign up for the outdoor sports courses offered by the department: water tourism - river rafting, windsurfing, beach volleyball, hiking and other hobby sports. The lessons in the courses are focused on the development of basic and special movement skills and, mastering the techniques needed for the sports.
Creating a positive and lasting relationship with physical activity. Acquisition and mastery of basic motor skills and abilities in outdoor sports: windsurfing, beach volleyball, water tourism - river rafting, hiking and other sports according to interest. Training and improving the technique needed for the sports.
Improvement training in a selected sport aimed at enhancing locomotion skills in the selected sport. To improve the students´ resistance against various vices, stresses and risk factors.
Slovak, English
Practicing of offensive and defensive game combinations and playing with modified rules in collective sports such as basketball, volleyball, football, floorball, hockey. Command of elements of higher difficulty in locomotion skills (swimming - crawl stroke, breast stroke, butterfly stroke, trampoline jumping and aerobics – practicing of areobics compositions, bodybuilding – development of the main muscle groups, paddling on running water. Testing of the level of physical fitness and coordination skills.
100/0
Russell S., Norwig P. (2010). Artificial Intelligence: A Modern Approach, (3rd ed.), Prentice Hall. Available in faculty library.
Marsland S. (2015). Machine Learning: An Algorithmic Perspective, (2nd ed.), CRC Press.
Passing the online course https://course.elementsofai.com/ (in Enlish or Slovak version).
Slovak or English
The course consists of 20 numerical and 5 text-based tasks. Numerical tasks are checked automatically, text-based tasks are evaluated anonymously by students.
1. What is artificial intelligence: related areas, AI philosophy.
2. Troubleshooting and UI: Browsing and troubleshooting, browsing and games
3. Probability and chance, Bayes' theorem, naive Bayesian classification.
4. Machine learning: nearest neighbor classifier, regression.
5. Neural networks: basics, creation, modern techniques.
6. Consequences: on predicting the future, the effects of AI on society, summary.
The student will get acquainted with selected basic concepts of artificial intelligence and their use in solving various practical tasks.
Russell S., Norwig P. (2010). Artificial Intelligence: A Modern Approach, (3rd ed.), Prentice Hall. Available in faculty library.
Marsland S. (2015). Machine Learning: An Algorithmic Perspective, (2nd ed.), CRC Press.
Passing the online course https://course.elementsofai.com/ (in Enlish or Slovak version).
Slovak or English
The course consists of 20 numerical and 5 text-based tasks. Numerical tasks are checked automatically, text-based tasks are evaluated anonymously by students.
1. What is artificial intelligence: related areas, AI philosophy.
2. Troubleshooting and UI: Browsing and troubleshooting, browsing and games
3. Probability and chance, Bayes' theorem, naive Bayesian classification.
4. Machine learning: nearest neighbor classifier, regression.
5. Neural networks: basics, creation, modern techniques.
6. Consequences: on predicting the future, the effects of AI on society, summary.
The student will get acquainted with selected basic concepts of artificial intelligence and their use in solving various practical tasks.
- Teachers' own electronic study materials published on the course website or in the Moodle system
- Gavora, Peter a kol. 2010. Elektronická učebnica pedagogického výskumu. [online]. Bratislava : Univerzita Komenského, 2010. Dostupné na: http://www.e-metodologia.fedu.uniba.sk/ ISBN 978–80–223–2951–4.
- Tharenou, P., Donohue, R. and Cooper, B., 2007. Management research methods. Cambridge University Press.
- Topping, A., 2015: The Quantitative-Qualitative Continium. In: Gerrish, K. and Lathlean, J., The Research Process in Nursing, p. 159-172
- Williamson, K. and Johanson, G. eds., 2017. Research methods: Information, systems, and contexts. Chandos Publishing.
Continuous assessment: active participation in research in an international student team (25%), presentation of work in a workshop (25%), scientific article (50%)
Indicative evaluation scale: A 90 %, B 80 %, C 70 %, D 60 %, E 50 %
English
- Research methodology
- Design and implementation of a research project in an international group (preferably interdisciplinary)
- Methods and tools for collaboration in virtual space, collaboration in science and practice
- Academic writing, presentation of research results through scientific articles; objectives, content and structure of scientific articles; forms of academic publication, publication forums and evaluation of their quality
- Quality assurance and feedback - peer review
- Communication of results through posters or conference presentations
100/0
Students will learn in the team to agree on a common research topic, formulate research questions, determine research methods for the problem, collect and evaluate data, discuss their findings, present research results to the professional public, analyze and evaluate the scientific work of their colleagues, prepare a scientific article suitable for publication
2/1 (lecture / individual work)
Clark, Timothy R., et al. Business Model Generation. Wiley, 2010
The condition for admission to the exam is active participation in at least 80% of the lessons.
The final assessment consists of a presentation of the semester project. To successfully complete the course, it is necessary to achieve at least 50% of the overall score.
Slovak
1. Commercialization of scientific research.
2. Fundamentals of entrepreneurship and startup terminology.
3. Identification of problems and customer needs analysis (design thinking).
4. Technology transfer. Technology Readiness Levels (TRL).
5. Intellectual property and its protection.
6. Market, customer, and market potential of a technological solution.
7. Business Model Canvas. Revenue models.
8. Sources of financing for technological projects.
9. Pitching and communication of the solution.
10. Fundamentals of management and leadership.
11. Innovation support and incubation structures at national and international levels.
0/100
After completing the course, students can describe the possibilities for commercialization of scientific and technological research. They can identify market needs, assess the market potential of a technological solution, and are familiar with the terminology of entrepreneurship, technology transfer, and intellectual property protection. They understand the overall structure of a business plan and the main forms of financing for technological projects. They are familiar with the principles of communication, teamwork, and team leadership and can apply them appropriately in project work and its presentation.
To improve the students´ physical fitness, health and sport performance through sport.
Slovak, English
To improve offensive and defensive game combinations in collective sports. Practicing of tactical and technical elements in individual sports. Compensatory exercises to correct wrong body posture. Stretching. Competition rules in sport disciplines.
100/0
To strengthen the procedural aspect of university sport, stressing its health and psychological importance. To improve the students´ physical fitness.
Slovak, English
Sport training for Faculty Championships in a selected sport with modified rules. Selection of sport-talented students into teams of the Faculty Sport League, University League of Bratislava Faculties, and participation in sport events of the Faculty and University.
100/0